Generic Name: acetaminophen and hydrocodone Brand Names: Anexsia, Dolorex Forte, Hycet, Liquicet, Lorcet 10/650, Lorcet

Plus , Lortab 10/500, Lortab 2.5/500, Lortab 5/500, Lortab 7.5/500, Lortab Elixir, Ma xidone, Norco, Polygesic, Stagesic, Vicodin, Vicodin ES, Vicodin HP, Xodol, Xodo l 5, Zamicet, Zydone Subclass:Opioid Combos Adult Dosing . Dosage forms: 5/500 pain, moderate-mod. severe [2.5-10 mg hydrocodone PO q4-6h prn]Max: 1 g/4h and 4 g/day acetaminophen renal dosing [not defined]renal impairment: consider decr. dose hepatic dosing [not defined]hepatic impairment: consider decr. dose Mechanism of Action acetaminophen exact mechanism of action unknown, produces analgesia and anti-pyr etic effects; hydrocodone binds to various opioid receptors, producing analgesia and sedation Hydrocodone is in a group of drugs called narcotic pain relievers. Acetaminophen is a less potent pain reliever that increases the effects of hydro codone. The combination of acetaminophen and hydrocodone is used to relieve moderate to severe pain. side effects feeling anxious, dizzy, or drowsy; mild nausea, vomiting, upset stomach, constipation; headache, mood changes; blurred vision; ringing in your ears; or dry mouth. serious side effects: shallow breathing, slow heartbeat; feeling light-headed, fainting; confusion, fear, unusual thoughts or behavior; seizure (convulsions); problems with urination; or nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools , jaundice (yellowing of the skin or eyes). Contraindications/Cautions . hypersens. to drug/class/compon. caution in elderly pts caution in debilitated pts caution if hepatic impairment caution if renal impairment caution if drug abuse hx caution if alcohol use caution if pulmonary impairment

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