Generic Name: fluticasone nasal Brand Names: Flonase, Veramyst Subclass:Nasal Sprays, Corticosteroid Adult Dosing .

Dosage forms: 27.5 mcg/spray allergic rhinitis [2 sprays/nostril qd]Max: 2 sprays/nostril/day; Info: decr. to 1 spray/nostril q d if sx controlled renal dosing [no adjustment] hepatic dosing [not defined]severe impairment: caution advised Mechanism of Action exact mechanism of anti-inflammatory action unknown; inhibits multiple inflammat ory cytokines; produces multiple glucocorticoid and mineralocorticoid effects Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation. Fluticasone nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies Common Reactions headache nasopharyngitis epistaxis pyrexia pharyngolaryngeal pain cough Serious Reactions nasal ulcer nasal/oral candidiasis growth suppression (peds pts) IOP incr. glaucoma cataracts hypercorticism adrenal suppression hypersensitivity rxn anaphylaxis Drug Interactions . Avoid/Use Alternative boceprevir conivaptan HIV protease inhibitors telaprevir Contraindications/Cautions . hypersens. to drug/class/compon. nasal septal ulcer, unhealed unhealed nasal surgery or trauma wound

caution caution caution caution caution caution caution caution caution

if if if if if if if if if

local or systemic infxn, untreated TB infxn ocular HSV infxn measles or varicella exposure IOP incr. glaucoma cataracts adrenal suppression/hypercorticism adrenal insufficiency

MAO inhibitor use w/in 14 days pts <6 yo Tourette syndrome or family hx motor tics agitation cardiac structural abnormalities cardiomyopathy arrhythmias, severe CAD, severe glaucoma caution if cardiovascular dz or hx caution if HTN caution if psychosis caution if bipolar disorder caution if seizure hx or risk caution if substance abuse hx caution if hyperthyroidism caution if PKU (phenylalanine-containing forms)