]Heart Abbre viatio n

Secreted hormone

From cells

Effect

Atrialnatriuretic peptide Brain natriuretic peptide

Reduce blood pressure by: ANP Cardiac myocytes reducing systemic vascular resistance, reducing blood water, sodium and fats (To a lesser degree than ANP) reduce blood pressure by: BNP Cardiac myocytes reducing systemic vascular resistance, reducing blood water, sodium and fats

Adipose tissue
Secreted hormone From cells Effect

decrease of appetite and increase of metabolism. Leptin (Primarily) Adipocytes Signals to eat more when fat storages are low and eat less when fat storages are high

adiponectin

Adipocytes

glucose regulation and fatty acid oxidation.

Liver
Abbrevia tion

Secreted hormone

From cells

Effect

Insulin-like growth factor (or somatomedin) (Primarily)

insulin-like effects IGF Hepatocytes regulate cell growth and development vasoconstriction

Angiotensinogen and angiotensin Thrombopoietin

Hepatocytes Hepatocytes

release of aldosterone from adrenal cortex, its a dipsogen. stimulates megakaryocytes to produce platelets
[3]

Kidney
Secreted hormone From cells Effect

Renin (Primarily)

Juxtaglomerular cells

Activates the renin-angiotensin system by producing angiotensin I of angiotensinogen

Erythropoietin (EPO)

Extraglomerular mesangial cells

Stimulate erythrocyte production

Cacitriol (1,25 dihydroxyvitamin D3) Thrombopoietin

Active form of vitamin D3 Increase absorption of calcium and phosphate from gastrointestinal tract and kidneys ,inhibit release of PTH stimulates megakaryocytes to produce platelets[3]

PDGFs are mitogenic during early developmental stages, driving the proliferation of undifferentiated mesenchyme and some progenitor populations. During later maturation stages, PDGF signalling has been implicated in tissue remodelling and cellular differentiation, and in inductive events involved in patterning and morphogenesis.

EGF results in cellular proliferation, differentiation, and [5] survival. EGF is a low-molecular-weight polypeptide first purified from the mouse submandibular gland, but since then found in many human tissues including submandibular gland, parotid gland. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion

NGF is critical for the survival and maintenance of sympathetic and sensory neurons. Without it, these neurons [5] undergoapoptosis. Nerve growth factor causes axonal growth.

It also functions as a signaling molecule