Name of Drug Ascorbic acid Brand Name: Vita-C Dosage/Route: 100300 mg/d in divided doses Drug Class: Vitamins

Mode of Action Increases protection mechanism of the immune system, thus supporting wound healing. Necessary for wound healing and resistance to infection.

Indication Prophylaxis and treatment of scurvy and as a dietary supplement.

Contraindication Use of sodium ascorbate in patients on sodium restriction; use of calcium ascorbate in patients receiving digitalis. Safety during pregnancy (category C) or lactation is not established.

Side effect Nausea, vomiting, diarrhea

Nursing Consideration Take large doses of vitamin C in divided amounts because the body uses only what is needed at a particular time and excretes the rest in urine Megadoses can interfere with absorption of vitamin B12. Note: Vitamin C increases the absorption of iron when taken at the same time as ironrich foods.

Name of Drug Ciftazidime Brand Name: Tazidime Dosage/Route: 400mg IVT q8hr (ANST)

Mode of Action Inhibits synthesis of bacterial cell wall, causing cell death.

Indication CNS infections

Contraindication Side effect Contraindicated to Headache, dizziness, patients with allergies nausea, vomitting to penicillins, cepahlosporins.

Nursing Consideration Assess for liver and renal dysfunction. Culture infection, and arrange sensitivity tests before and during therapy if

Drug Class: Antibiotic Cephalosporin (third generation)

expected response is not seen. Warning: Do not mix with aminoglycoside solutions, administer these drugs separately. Powder and reconstituted solution darken with storage. Have Vit. K available in case hypoprothrombinemia occurs Discontinue if hypersensitivity occurs Teach SO that patients may experience upset stomach or diarrhea but must report severe diarrhea, difficulty breathing, fatigue, pain at injection site.

Name of Drug Vitamin B complex Brand Name: Pharex Dosage/Route: 10-20 tab/ Day TID Drug Class: Vitamins and Minerals

Mode of Action A coenzyme that stimulate metabolic function and is needed for cell replication, hematopoiesis, and nucleoprotein and myelin synthesis.

Indication Pernicious anemia

Contraindication hypersen-sitive to vitamin B12 or cobalt. early Lebers disease

Side effect Itching, burning or pain at injection site

Nursing Consideration BEFORE: Determine reticulocyte count, hct, Vit. B12, iron, folate levels before beginning therapy. Obtain a sensitivity test history before administration Avoid I.V. administration bec. faster systemic elimination will reduce effectiveness of vitamin. DURING: Dont give large doses of vitamin B12 routinely; drug is lost through excretion. Dont mix parenteral preparation in same syringe with other drugs. AFTER: Protect Vit. B12 from light. Dont

refrigerate or freeze. Monitor patient for hypokalemia for first 48 hours, as anemia correct itself.

Name of Drug Generic Name: rifampicin Brand Name: Crisarfam Dosage/Route: 200mg/5mL OD Drug Class: Antiinfectives

Mode of Action Inhibits DNAdependent polymerase, decreases replication.

Indication Maintenance phase treatment of all forms of pulmonary and extra-pulmonary TB; prevention of meningococcal meningitis.

Contraindication Jaundice associated with reduced bilirubin exretion; 1st trimester of pregnancy; premature and newborn infants. Drug-induced liver diseas, impaired liver function.

Side effect Diarrhea, bleeding

Nursing Consideration Perform mycobacterial studies and susceptibility. Assess lung sounds and character and amount of sputum periodically. Monitor patient compliance with treatment regimen. Do not take any medication during therapy w/o consulting physician. Take rifampin on an empty stomach, 1 hour or after meals. This medication will discolor urine, stool,

saliva, tears, sweat, and other body fluid a red-brown color.

Name of Drug Generic Name: isoniazid Brand Name: Norvit Dosage/Route: 200mg/5mL OD Drug Class: Antiinfectives

Mode of Action Inhibits RNA synthesis, decreases tubercle bacilli replication.

Indication Pulmonary and extra pulmonary tuberculosis (TB).

Contraindication Should not be given to patients with drug induced liver disease.

Side effect Various skin eruptions, fever

Nursing Consideration Assess laboratory examinations. Monitor liver/renal function. Instruct patient that compliance with dosage schedule for duration is necessary to gain benefits. Caution patient in alcohol while in therapy may increase risk of liver damage. Tell patient to report peripheral neuritis.

Name of Drug Generic Name: pyrazinamide

Mode of Action

Indication

Contraindication
Acute-liver disease, porphyria, peripheral neuritis, acute gout,

Side effect
Dose-related hepatoxicity, N/V, anorexia,

Nursing Consideration
Assess patients condition before therapy and regularly

Mechanism unknown, Treatment of active tuberculosis in adults highly specific and

and selected children

Brand Name: Mycobak Dosage/Route: 200mg/5ml 6ml OD Drug Class: Antiinfectives

bactericidal for Mycobacterium tuberculosis hominis.

hypersensitivity and pregnancy.

thrombocytopenia, increased serum iron concentration and adverse effects on blood clotting mechanisms.

thereafter to monitor drug effectiveness. Monitor serum uric acid which may be elevated and cause gout symptoms. Regularly assess for hepatoxicity. Regularly assess renal status. Instruct patient to take drug continuously as prescribed. Remind patient to comply with follow-up schedule.

Name of Drug Brand Name: Calmoseptine Cream Dosage/Route: Topical BID Frequency: as needed on affected areas

Mode of Action Calmoseptine Ointment is an analgesic, antiseptic, antipruritic, and skin protectant combination. It works by temporarily relieving itching and pain. It also decreases moisture in the affected area.

Indication Preventing and treating minor skin irritations (eg, caused by cuts, scrapes, minor burns, perspiration, itching, wound drainage).

Contraindication you are allergic to any ingredient in Calmoseptine Ointment you are treating a deep wound or puncture wound

Side effect Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

Nursing Consideration for external use only. Do not get it in your eyes, nose, or mouth. If you get it in any of these areas, rinse at once with cool water. Do not use Calmoseptine Ointment to treat deep wounds or puncture wounds.