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20115820 World Health Digest Medical Periodieal

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[1] .[J].
, 2005, 20(16) : 43-44.

16

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R331.3A1672-5085201120-0093-06

[1-5]



O2CO2 PHNMDA
O2ATP
5-10
O2


A Review of <Timer Role of Blood Circulation When Brain Processing information>
Abstract After publish of < Storing and Re-engineering of Models of Cerebral Information Process >and
<Timer Role of Blood Circulation when Brain Processing Information>, some peers fed back that those papers are
hard to understand. In order to make the theory easier to be understood, this paper gives a brief review of [1-5],
including four parts. Part 1 gives a brief review of evidences that support blood circulation has timing control
function when brain processing information: (1) Because the diameters of capillaries can be smaller than a pyramid
cell, artery blood can engender concentration differences of matters brought by itself in a spatial precision of a
single cell. (2)Because blood vessels can relatively maintain their modal stability in a time scale of second, the sub
networks that formed by microcirculation mechanism when processing different information have relative stability
and changeability. (3)Transport speeds of some matters (e.g. O2, CO2) from capillaries to tissue (or from tissue to
capillaries) are quick enough, so that concentration differences of these matters can be engendered as soon as artery
blood arrives. (4)Concentration differences that have been engendered are able to effect information processing. For
example, H+ can depress NMDA receptors; O2 effects the production of ATP. (5) One will lost conscious 5-10
seconds after stop of blood supply, this time scale is same with active periods of micro arteries and capillaries.(6)Some
matters brought by artery blood are bottle neck matters of biochemical reactions, e.g. O2.(7)EEG phenomena
that are mentioned in the EEG model we have built. Part 2 gives a brief review of the EEG model that we have
built. With the help of some math tools from artificial intelligence area (e.g. Structure risk minimization etc.),
Part 3 explains why timing control function of blood circulation is important when brain processing information
efficiently; and explains why physiology structures and mechanisms that are able to organize respective sub networks
(e.g. language mechanism, hippocampus formation etc.) when brain processing different information are important
when brain processing information efficiently. Part 4 introduces some viewpoints of model of process storing and
recalling.
Key wordsmodel of process storing and recalling EEG blood circulation timing control Structure risk
minimization time cognition information process CNS micro circulation

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[1-5]

[1-5]1
[6]

,O2C O24
P H
NMDA[7]O2
, A T P5

5-10[6]
6
O27

2
3H Z

4
5
6
balance traces switching
7
[1-5]

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20115820 World Health Digest Medical Periodieal

Fig.1 Abstract modeling of thickness wave of


matters brought by artery blood, wave and AMS of
wave

2
Fig.2 Domain of Concentration wave define domain
of wave

20115820 World Health Digest Medical Periodieal

5
Fig.5 Basic framework of EEG model

3
Fig.3 Domain of Concentration wave define domain
of AMS of wave

6 23HZ
Fig.6 About formation of 23HZ wave

7
Fig.7 Concept of balance traces switching
3

Fig.4 Decrease of concentration of matters brought


by artery blood result in decrease of amplitude of AMS

8
Fig.8 Illusion about how brain processing a graphic
* GG

* When brain processing a piece of information (e.g.


a graphic G pop up in our mind), its required
that some special cells are active (tag with red), and
other cells are depressed (tag with blue or white).

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Arrival of artery blood can increase activity differences


among red cells and blue cells, and among cells inside
and outside area G.
3.1

[10]

[11]

3.2
,

1[11]

2H o p f i e l d[11]
Hopfield
[12]Hopfield

Hopfield
Hopfield
3
[11]
9

Fig.9 Microcirculation system has the capability


of organizing respective sub networks when processing

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20115820 World Health Digest Medical Periodieal

different information

3.3

3.3.1
(1

10

10
Fig.10 When modeling, just need to consider
t h e c e l l-c o n n e c t i o n-c h a n g i n g s t h o s e a r e l a r g e r
enough, because just them can survive kinds of forget
mechanisms
(2

(3

11

11
Fig.11 Treat network with reactive circuits as a set
of networks without reactive circuits
3.3.2
(1

1213

20115820 World Health Digest Medical Periodieal

12
Fig.12 Illustration of neural network training

13 2
Fig.13 Illustration of neural network training 2
(2

(3
V C3.3.1

(43.3.1

(5
14

14

Fig.14 The illustration about how timing control


function of blood circulation organize respective sub
networks when brain processing different information
4
(1

(2
O2C O2
5-H T

5-H T

LSD
(3

(4


[1]
[J]2007(3)432-435439.
X i e Q i n, W a n g Y i-r o n g. S t o r i n g a n d R eengineering of Models of Cerebral Information Process [J].
Progress of Modern Biomedicine, 2007,(3):432-435,439.
[2]
[J]2008(6)1152-1159.
Xie Qin. Timer Role of Blood Circulation When
Brain Processing Information [J].Progress of Modern
Biomedicine, 2008, (6):1152-1159.
[3] [Z]www.sciam.com.

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20115820 World Health Digest Medical Periodieal

cn2006.
Xie Qin. Model of Process Storing and Recalling [Z].
www.sciam.com.cn, 2006.
[4] [C]

2007:144.
Xie Qin. A Viewpoint about origin and meaning of
EEGs[C].Proceedings of the 7th Biennial Meeting and the
5th Congress of the Chinese Society for Neuroscience.
Beijing: Science Press, 2007:144.
[5]
[C]
:, 2009: 135.
Xie Qin. A Review of <Timer Role of Blood
Circulation When Brain Processing Information>[C].
Proceedings of the 8th Biennial Meeting of the Chinese
Society for Neuroscience. Beijing: Science Press. 2009:
135.
[6] (8
)[M]:. 2005: 503-504.
Y a o T a i, C a o J i-m i n, F a n X i a o-l i, e t a l.
Physiology (Textbook for 8-year students of Medical)[M].
Beijing: Peoples Medical Publishing House. 2005:
503-504.
[7] [M]:

. 2002: 121.
Guan Xin-min, Han Ji-sheng, et al. Medical
Neurobiology [M]. Beijing: Peoples Medical Publishing
House. 2002: 121.
[8] . [M]:
. 2005.
Okuma T(Author),Zhou Jin-hua(Translator).Clinical
Electroencephalogram [M].Beijing: Tsinghua Publishing
house. 2005.
[9] . [M]:
.1984.
H u a n g Y u a n-g u i, W u S h e n g-l i n g.C l i n i c a l
E l e c t r o e n c e p h a l o g r a m [M].X i a n: S h a n x i S c i e n c e
Publishing House.1984.
[10] Ramura S, Tateishi M. Capabilities of FourLayered Feedforward NN, Four Layers Versus Three
Layers[J]. IEEE Trans NN, 1997, 2(8):251-255.
[11]
[M]:.2004.
Yan Ping-fan, Zhang Chang-shui. Artificial Neural
Networks and Evolutionary Computing[M]. Beijing:
Tsinghua Publishing House. 2004.
[12] B r a c k J. O n t h e N u m b e r o f S p u r i o u s
Memories in the Hopfield Model[J]. IEEE Trans, 1990,
IT-36:393-397.

032200

R521A1672-5085201120-0098-02
X 2009720107X

0.19%
020

Abstract Objective: X-ray examination, to understand the incidence of TB in our city. Methods: Hospital
from July 2009 to July 2010 Department of Radiology, X-ray examination was initially diagnosed as TB statistics for
verification, one by one category list. Results: The new TB patients who inspected the number of total 0.19%, the
overall incidence is relatively low. Conclusion: the state of TB prevention of newborn children has invested heavily,
making the 0-20 age group the proportion of TB patients was significantly reduced. On the other hand, due to the
constant improvement of medical conditions and the development of a reasonable and timely application of anti-TB
drugs, so patients can find and control the disease earlier, received better treatment.

200971201071
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200972010734377
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75.3%
1.2.2
212109
51.4%10348.6%1:1647
39060.27%25739.72%
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WORLD HEALTH DIGEST


2011,8(20)

http://d.g.wanfangdata.com.cn/Periodical_zwjkwz201120078.aspx

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