Professional Documents
Culture Documents
Scottish Dental Clinical Effectiveness Programme Dundee Dental Education Centre, Frankland Building, Smalls Wynd, Dundee DD1 4HN Email scottishdental.cep@nes.scot.nhs.uk Tel 01382 425751 / 425771 Website www.scottishdental.org/cep
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1 Introduction ........................................................................................................................ 1 1.1 Scope.................................................................................................................................. 1 1.2 Style and Format.................................................................................................................. 1 1.3 Statement of Intent .............................................................................................................. 2 1.4 Overarching Principles .......................................................................................................... 2 2 Pathways to Providers of Care Decision Support ............................................................. 5 2.1 Patient Presenting with Pain .................................................................................................. 6 2.2 Patient Presenting with Swelling ............................................................................................ 7 2.3 Patient Presenting with Bleeding............................................................................................ 8 2.4 Patient Presenting with Injury Caused by Trauma ................................................................... 9 2.5 Patient Presenting with Altered Sensation or Abnormal Appearance ........................................ 11 2.6 Patient Presenting with Ulceration........................................................................................ 12 2.7 Decision Support Pathway Endpoints.................................................................................... 13 3 Management of Oral Conditions........................................................................................ 15 Common Oral Conditions...................................................................................................... 15 3.1 Pulpitis .............................................................................................................................. 15 3.2 Acute Apical Abscess .......................................................................................................... 16 3.3 Acute Periodontal Conditions ............................................................................................... 17 3.4 Post-extraction Haemorrhage .............................................................................................. 19 3.5 Acute Pericoronitis (including Erupting Teeth in Children)....................................................... 20 3.6 Alveolar Osteitis (Dry Socket) .............................................................................................. 22 3.7 Fractured, Loose or Displaced Tooth Fragments and Restorations........................................... 23 3.8 Oral Ulceration ................................................................................................................... 24 3.9 Ill-fitting or Loose Dentures................................................................................................. 26 3.10 Fractured or Displaced Orthodontic Appliances .................................................................... 27 3.11 Sinusitis ........................................................................................................................... 27 Less Common Oral Conditions.............................................................................................. 29 3.12 Salivary Gland Obstruction or Infection............................................................................... 29 3.13 Bells Palsy ....................................................................................................................... 30 3.14 Injuries to the Mouth, Face and Jaws ................................................................................. 31 3.15 Acute Temperomandibular Joint Conditions......................................................................... 34 3.16 Candidal Infection (Oral Thrush) ........................................................................................ 35 3.17 Intra-oral Swellings and Altered Appearance ....................................................................... 36 Rare Oral Conditions ............................................................................................................ 38 3.18 Trigeminal Neuralgia......................................................................................................... 38 3.19 Anaesthesia, Paraesthesisa, Dysaesthesia ........................................................................... 39 3.20 Osteonecrosis................................................................................................................... 40 3.21 Peri-implantitis ................................................................................................................. 41 3.22 Temporal Arteritis ............................................................................................................. 42 Appendix 1 Guidance Development .................................................................................... 43 Appendix 2 Analgesia .......................................................................................................... 46 Providing Self-help Advice on Managing Dental Pain.................................................................... 46 Analgesic Prescribing for Pain Relief........................................................................................... 47 Appendix 3 Adverse Drug Reactions and Side Effects ........................................................ 52
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1 Introduction
The clinical services provided for patients with acute dental problems are variable (Ball 2008; Anderson et al 2005; Anderson 2000). Some patients may have to reattend for a procedure to be repeated or for alternative treatment because the initial care itself was sub-optimal. Patients attending for unscheduled care with pain or infection that requires a clinical intervention may be prescribed antibiotics inappropriately (Ellison 2008; Runyan 2004; Sweeney 2004). For less frequently encountered problems, such as dental trauma and certain medical conditions, there might be more uncertainty about the care that should or can be provided (Tulip 2008). Notably, a significant proportion of the population only seek dental care when they suffer an acute episode and may initially present to other providers of care (e.g. general medical practitioner, accident and emergency, pharmacy). To address variation in practice and to improve the quality of unscheduled clinical care for patients with acute dental problems, the Scottish Dental Clinical Effectiveness Programme (SDCEP) convened a guidance development group to provide clinical guidance on best practice for the Management of Acute Dental Problems. The draft guidance developed by this multidisciplinary group builds on the Emergency Dental Care guidance published by SDCEP in 2007, the experience of managing dental calls within NHS 24 and research evidence on treatment of the wide range of conditions that may present (SDCEP 2007). Further information about development of this guidance is provided in Appendix 1.
1.1 Scope
The guidance aims to encourage a consistent approach to the management of acute dental problems, provide a standard for the initial management of presenting symptoms for patients with acute dental problems and advise patients on the appropriate subsequent care and/or referral to appropriate treatment providers if applicable. The proposed recommendations for management may be used by NHS Boards to improve the quality of care provided irrespective of when the patient seeks care. The guidance focuses on initial management and subsequent care to address the presenting problem. Longer term care planning is beyond the scope of this guidance. The guidance is designed for use by all sectors directly involved in provision of care for patients with acute dental problems, including general dental practice, community and salaried dental practice, outof-hours services, general medical services, hospital dental services, accident and emergency departments, pharmacies, and the Scottish Ambulance Services. The guidance is applicable to patients of all ages in all population groups, irrespective of the healthcare setting or whether or not they are regular attenders for routine dental care. The guidance is also of relevance to those involved in dental education and undergraduate training.
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influence the choice of care options. Instead the range of issues or approaches to be considered are provided, and clinical detail has been kept to a minimum. References used to inform the guidance text are included at the end of each subsection in Section 3. If no references are listed, the guidance has been based on the opinion of experts and experienced practitioners within the Guidance Development Group. Depending on their current knowledge, users with different professional backgrounds are likely to differ in the way they use the guidance. Some might use the decision support pathways as a means of accessing the appropriate advice on specific conditions. Others might go directly to the advice on specific conditions. Advice on analgesia and adverse drug reactions are provided in Appendices 2 and 3 respectively.
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Therefore, when prescribing drugs, please refer to Appendix 1 of the BNF (www.bnf.org) and BNFC (www.bnfc.org) for comprehensive information on drug interactions.
For more details refer to the SDCEP Oral Health Assessment Guidance (SDCEP 2011B). Good record-keeping underpins the provision of quality patient care (OMalley 2009; British Dental Association 2009). Increasingly, the care of patients is shared among dental team members and between other professionals. Therefore, it is important to ensure all relevant information is available to facilitate the provision of safe, shared care of patients. This might also prove useful in the event of complaints or for medico-legal reasons (MDDUS 2009). For more details visit SDCEPs Practice Support Manual online (SDCEP 2010). References: Anderson R, Thomas DW. Out-of-hours dental services: a survey of current provision in the United Kingdom. British Dental Journal 2000; 188: 269-274. Anderson R, Thomas DW, Phillips CJ. The effectiveness of out-of-hours dental services: I. pain relief and oral health outcome. British Dental Journal 2005; 198: 91-97. Ball GE. Out-of-hours emergency dental services in Scotland a national model. British Dental Journal 2008; 205: 485-487. British Dental Association. Advice sheet B1: ethics in dentistry, BDA Practice Compendium; 2009 (www.bda.org/pct-healthbody/pcts/advicesheet.aspx). Byers J, Lowe T, Goodall CA. Acute cervico-facial infection in Scotland 2010: patterns of presentation, patient demographics and recording of systemic involvement. British Journal of Oral and Maxillofacial Surgery 2011; doi:10.1016/j.bjoms.2011.11.013. Ellison SJ. An outcome audit of three day antimicrobial prescribing for the acute dentoalveolar abscess. British Dental Journal 2011; 2011; 211: 591-4. Ellison SJ. The role of phenoxymethylpenicillin, amoxicillin, metronidazole and clindamycin in the management of acute dentoalveolar abscesses a review. British Dental Journal 2009; 206: 357-362. MDDUS. Essential guide to medical and dental records. Glasgow: The Medical and Dental Defence Union of Scotland; 2009 (www.mddus.com/mddus/resource-library/mddus-booklets/essential-guide-tomedical-and-dental-records.aspx). OMalley D. Clinical examination and record keeping: good practice guidelines, 2nd edition. London: Faculty of General Dental Practitioners (UK); 2009.
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Runyan MS, Brennan MT, Batts JJ et al. Efficacy of Penicillin for dental pain without overt infection. Academic Emergency Medicine 2004; 11: 1268-1271. SDCEP. Drug prescribing for dentistry: dental clinical guidance, 2nd edition. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011A (www.sdcep.org.uk/index.aspx?o=2334). SDCEP. Oral health assessment and review: guidance in brief. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011B (www.sdcep.org.uk/index.aspx?o=2336). SDCEP. Practice support manual 2010 (www.psm.sdcep.org.uk/). SDCEP. Emergency dental care: dental clinical guidance. Dundee: Scottish Dental Clinical Effectiveness Programme, 2007 (www.sdcep.org.uk/index.aspx?o=2335). Sweeney LC, Dave J, Chambers PA, Heritage J. Antibiotic resistance in general dental practice a cause for concern? Journal of Antimicrobial Chemotherapy 2004; 53: 567-576. Tulip DE, Palmer NOA. A retrospective investigation of the clinical management of patients attending an out of hours dental clinic in Merseyside under the new NHS dental contract. British Dental Journal 2008; 205: 659-664.
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An additional ulceration pathway is included in Section 2.6 that is linked to the pain pathway. It is recognised that a patient may present with more than one of these symptoms. In this case, the main or first reported symptom is used as the start point. Pathway key:
Yes
No
Actions for initial assessment or management of the patient Endpoints that indicate the recommended timescale and care provider
Advise optimal analgesia. Avoid stimuli
This number refers to an entry in Section 2.7 of this guidance, which lists conditions that share the presenting symptoms that lead to this endpoint.
When the endpoint is Self-care, the patient should be able to manage the problem without the need for further involvement of a healthcare professional. However, the patient needs to be advised that if the symptoms persist or worsen, they should contact a dentist or general medical practitioner. These flowcharts are included as a means of illustrating pathways to care providers based on presenting symptoms. It is intended to provide a decision support tool based on the information contained within these flowcharts in more user-friendly electronic formats (web-, tablet- and/or smart phone-based). 5
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Assess whether the patient has: 1) atypical jaw pain and any other signs of myocardial infarction (MI), e.g. breathlessness OR 2) exceeded the recommended dose of over the counter pain relief medication with the past 24 hours (noting other factors e.g. child, elderly, lack of food)
Yes
No
Is there swelling? Go to Swelling pathway (Section 2.2)
Yes
Advise chlorhexidine mouthwash, optimal analgesia. If signs of spreading infection, consider prescribing metronidazole or amoxicillin
Urgent Dental Care within 24 hours Self-care unless problem persists or worsens
No
Adult tooth
Is the pain related to an erupting tooth? Is this an adult tooth or teething in a child?
Yes
Yes
Teething
No
No
Has analgesic been taken? Has analgesic controlled the pain?
Urgent Dental Care within 24 hours 2
Yes
No
2
No
Advise optimal analgesia. Avoid stimuli Has the patient had a recent tooth extraction? Advise optimal analgesia, patient to avoid smoking and to maintain good oral hygiene
Yes
Prompt Dental Care within 7 days
or if no improvement in 24 hrs
Yes
No
Is the pain in the face or the mouth? Is the pain from an ulcer? Go to Ulceration pathway (Section 2.6)
Mouth
Yes
Face
Urgent Dental Care within 24 hours 4
No
Advise optimal analgesia Avoid stimuli
Prompt Dental Care within 7 days 2
or if no improvement in 24 hrs
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Assess the degree of swelling: Is the patient having difficulty breathing? Can the patient easily stick tongue out/move tongue? Has the swelling worsened in the last hour?
Yes
No
Is the patient systemically unwell (e.g. rigors, increasing temperature, lethargic)?Note that a child or The patient will require antibiotics. If in nondental setting or dental care is unavailable, consider prescribing antibiotics
Yes
No
Is the Patient also in pain?
Yes
No
Advise the patient to see a dentist within 7 days or sooner if the symptoms worsen or become painful
5
Assess whether the patient has: 1) atypical jaw pain and any other signs of myocardial infarction (MI), e.g. breathlessness OR 2) exceeded the recommended dose of over the counter pain relief medication with the past 24 hours (noting other factors e.g. child, elderly, lack of food)
Yes
No
Go to on Pain pathway (Section 2.1)
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Has the patient had a recent dental extraction or other dental treatment
No
No
Yes
Yes
Advise patient to bite on moistened cotton handkerchief or gauze and maintain constant pressure for 20 minutes. Be aware that bleeding may be more persistent if the patient is taking blood thinners.
Yes
Go to Trauma pathway (Section 2.4)
No
Is the patient systemically unwell?
Emergency Medical Care via NHS24
Yes
No
Several conditions can cause low level bleeding. Assessment by a dentist is required.
7
Yes
No
No
Yes
Yes
Immediate Dental Care ideally within 60 minutes 6
Yes
Has the bleeding stopped? Is the bleeding severe?
Yes
No
No
Self-care unless problem persists or worsens Immediate Dental Care ideally within 60 minutes 6
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Has there been a head injury, loss of consciousness, significant facial trauma, is there uncontrollable Yes bleeding or is the airway compromised?
No
Assess and control any residual bleeding by applying pressure
Yes
Does the patient have large lacerations or lacerations across the tongue?
No
Most small intra-oral lacerations do not require suturing. Advise optimal analgesia and patient to use maintain good oral hygiene
No
Can the patient open and close their jaw and do their teeth/dentures meet together as they did before?
Yes
8
No
Yes
Go to trauma 2 pathway (Section 2.4.2)
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Yes
No
Has a tooth been knocked out? Is this an adult tooth? Place the tooth in milk. Avoid handling the root. Reimplantation has better success within 6 hrs or patient is <16 yrs old
Immediate Dental Care ideally within 60 minutes 8
Yes
Yes
No
No
Advise soft diet and analgesia (if required).
Yes
If available, cover exposed pulp with calcium hydroxide paste Is patient <16 years old or are symptoms severe?
Yes
Yes
No
Urgent dental care within 24 hours 8
No
No
Urgent dental care within 24 hours 8
Yes
Have any teeth moved? Is this an adult tooth?
Yes
Prompt dental care within 7 days 8
Yes
No
No
Advise optimal analgesia, if required
No
In many cases, further treatment is not necessary, but assessment by a dentist within 7 days is recommended. Advise soft diet and analgesia (if required).
8 Prompt dental care within 7 days
10
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Are there signs of stroke? e.g. Facial or Arm weakness, Speech problems Altered (F.A.S.T.) sensation
No
Advise the patient Has the to contact the patient had treatment provider recent dental or other within 7 days or treatment that Yes earlier if the might be the symptoms worsen. cause?
Abnormal appearance
Yes
Emergency Medical Care via NHS24
No
Urgent Dental Care within 24 hours 9
No
No
Prompt Dental Care within 7 days 10
Yes
Yes
Has this been present for more than 3 weeks?
No
Yes
Urgent Dental Care within 24 hours 10
OR
GMP within 24 hours
10
No
Go to Swelling pathway (Section 2.2)
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Has the patient been aware of the ulcer(s) for more than 3 weeks?
Yes
11
No
Is this the first time the patient has had this? There are several possible causes of recurrent painful oral ulceration and this normally requires further investigation by a dentist. Advise optimal analgesia (including topical) and use of chlorhexidine mouthwash*.
12
No
Yes
Does the patient have an underlying medical condition that may be associated with oral ulceration?
11 GMP within 24 hours
Yes
No
Is this a single ulcer?
Yes
Is the patient systemically unwell?
No
No
Yes
Has there been trauma from an adjacent tooth, orthodontic appliance or caused by loose or ill-fitting dentures? Advise optimal analgesia (including topical), use of chlorhexidine mouthwash and, as appropriate: Application of malleable wax to sharp nonYes removable parts of appliance causing trauma Patient to keep dentures out, where possible
A history of multiple painful oral ulceration may be due to herpes virus (or other rarer causes) and should be assessed by a dentist. Advise optimal analgesia (including topical) use of chlorhexidine mouthwash*.
13
No
Has the patient had recent dental treatment with local No anaesthetic? Advise optimal analgesia (including topical) and use of chlorhexidine mouthwash*.
Self-care unless problem persists or worsens
Yes
Ulcer is likely to be caused by trauma to anaesthetised soft tissues. Advise optimal analgesia (including topical) and for patient to avoid further trauma, hot drinks & smoking
Self-care unless problem persists or worsens
* Chlorhexidine mouthwash is not suitable for children under 7 years old because of its taste and their limited ability to rinse without swallowing
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Acute pericoronitis (including teething in children) [3.5] Pulpitis [3.1] Acute apical abscess [3.2] Acute periodontal conditions [3.3] Fractured, loose or displaced tooth fragments or restorations [3.7] Sinusitis [3.11] Osteonecrosis [3.20] Peri-implantitis [3.21]
Alveolar osteitis (Dry socket) [3.6] Pulpitis [3.1] Acute apical abscess [3.2] Acute periodontal conditions [3.3] Oral ulceration [3.8] Sinusitis [3.11] Salivary gland obstruction or infection [3.12] Acute temporomandibular joint conditions [3.15] Candidal infection (Oral thrush) [3.16] Trigeminal neuralgia [3.18] Osteonecrosis [3.20] Temporal arteritis [3.22] Acute apical abscess [3.2] Acute periodontal conditions [3.3] Acute pericoronitis (including teething in children) [3.5] Alveolar osteitis [3.6]
Salivary gland obstruction or infection [3.12] Intra-oral swellings [3.17] Osteonecrosis [3.20] Peri-implantitis [3.21]
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Fractured, loose or displaced tooth fragments or restorations [3.7] 8 Injuries to the mouth, face and jaws [3.14] Bells palsy [3.13] Intra-oral swellings or abnormal appearance [3.17] Trigeminal neuralgia [3.18] Anaesthesia, paraesthesia, dysaesthesia [3.19]
Oral ulceration [3.8] 10 Salivary gland obstruction or infection [3.12] Intra-oral swellings or abnormal appearance [3.17] Oral ulceration (including acute manifestations of malignant or systemic disease and adverse drug reactions or side effects) [3.8] Acute periodontal conditions [3.3] Acute pericoronitis (including teething in children) [3.5] Oral ulceration [3.8] Ill-fitting or loose dentures [3.9] Candidal infection (Oral thrush) [3.16] Intra-oral swellings or abnormal appearance [3.17] Fractured, loose or displaced tooth fragments or restorations [3.7] Oral ulceration [3.8] Ill-fitting or loose dentures [3.9] Fractured or displaced orthodontic appliances [3.10]
11
12
13
14
Common
Less common
Common
Common
Rare
Less common
Rare
Less Common
Acute periodontal conditions [3.3] Fractured, loose or displaced tooth fragments or restorations [3.7] Oral ulceration [3.8] Ill-fitting or loose dentures [3.9] Fractured or displaced orthodontic appliances [3.10] Salivary gland obstruction or infection [3.12] Candidal infection (Oral thrush) [3.16] Intra-oral swellings [3.17]
Common
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Initial management
Recommend analgesia (see Appendix 2). Do not prescribe antibiotics. Advise the patient to seek prompt dental care within 7 days or if analgesia ineffective, seek urgent dental care as soon as possible within 24 hours.
Subsequent Care
Determine if reversible or irreversible pulpitis. Reversible Pulpitis: Site of pain tends to be difficult to identify. Pain is short lasting and tends to decrease or disappear when stimulus (e.g. hot or cold, sweet food or drink) is removed. Consider: Providing a temporary dressing. Restoring the affected tooth.
Irreversible Pulpitis: Pain may be localised to a single tooth, may last for several hours, may be dull and throbbing, and may be worsened by heat. The pain can occur spontaneously, typically keeping the patient awake. Consider: Providing first stage endodontic therapy (pulpotomy for childrens teeth and pulpectomy for adults teeth). Extracting the tooth.
References: Chestnutt IG, Gibson J. Clinical Dentistry, 3rd edition. Edinburgh: Churchill Livingstone, 2007.
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Fedorowicz Z, Keenan JV, Farman AG, Newton T. Antibiotic use for irreversible pulpitis. Cochrane Database of Systematic Reviews 2005, Issue 2. Art. No.: CD004969. DOI: 10.1002/14651858. Levin LG, Law AS, Holland GR, Abbott PV, Roda RS. Identify and define all diagnostic terms for pulpal health and disease states. Journal of Endodontics 2009; 35(12): 1645-57. Mejare IA, Axelsson S, Davidson T, Frisk F, Hakeberg M, Kvist T, Norlund A, Petersson A, Portenier I, Sandberg H, Tranaeus S, Bergenholtz G. Diagnosis of the condition of the dental pulp: a systematic review. International Endodontic Journal 2012; doi: 10.1111/j.1365-2591.2012.02016.x. Mitchell L, Mitchell DA. Oxford Handbook of Clinical Dentistry, 5th edition. Oxford: Oxford University Press, 2009. Scully C (editor). ABC of oral health. Oxford: Wiley-Blackwell, 2000.
Initial management
Determine if the airway is compromised. Airway compromised: The patient is unable to swallow their own saliva or they are unable to push their tongue forward out of their mouth. Send the patient immediately to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Airway not compromised Recommend analgesia (see Appendix 2). Do not prescribe antibiotics unless there are signs of spreading infection (e.g. facial or neck swelling), systemic complications, or for an immunocompromised patient. Advise the patient to seek urgent dental care as soon as possible within 24 hours.
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Subsequent care
Consider: Initiating drainage of the abscess through the affected tooth if possible. If there is an associated fluctuant soft tissue swelling attempt incisional drainage as soon as possible. If able to drain through the tooth irrigate the canal with either 1 5.25 % Sodium Hypochlorite solution or 0.2% chlorhexidine gluconate solution before drying and sealing in non-setting Calcium Hydroxide using a temporary dressing material. Note that drainage is not normally carried out for a primary tooth. If drainage of the abscess through endodontic access is persistent, early recall and repeated cleaning of the canal may be necessary. The tooth should not be left on open drainage. Prescribing appropriate analgesia (NSAIDs) if attempts to drain the infection are inadequate, or if patient or clinician factors preclude immediate initiation of drainage (see Analgesic Prescribing section). Relieving occlusion on the affected tooth, if appropriate. Extracting the tooth, if appropriate (for a primary tooth this is usually considered as the first option; refer to secondary care if the child unable to tolerate pain for adjunctive sedation). Prescribing non-steroidal anti-inflammatory drugs to control post-operative pain following initial endodontic therapy.
References Canadian Collaboration on Clinical Practice Guidelines in Dentistry. Clinical Practice Guideline: Emergency management of an acute apical abscess in adults (full report). www.cccd.ca 2003. Chestnutt IG, Gibson J. Clinical Dentistry, 3rd edition. Edinburgh: Churchill Livingstone, 2007. Matthews DC, Sutherland S, Basrani B. Emergency management of acute apical abscesses in the permanent dentition: a systematic review of the literature. Journal of the Canadian Dental Association 2003; 69: 660. SDCEP. Drug prescribing for dentistry: dental clinical guidance, 2nd edition. Dundee: Scottish Dental Clinical Effectiveness Programme; 2011 (www.sdcep.org.uk/index.aspx?o=2334).
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Periodontal Abscess: Pain and tenderness of gingival tissue Increased tooth mobility Fever and regional lymphadenopathy Presence of swelling on gingiva along lateral side of root Suppuration through fistula or periodontal pocket Perio-Endo Abscess: Generalised periodontal disease may be present with localised pain Swelling +/- suppuration on palpation Deep pocketing to root apex with bleeding on probing
Initial management
Determine if the airway is compromised. Airway compromised: The patient is unable to swallow their own saliva or they are unable to push their tongue forward out of their mouth. Send the patient immediately to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Airway not compromised: Recommend analgesia (see Appendix 2). Do not prescribe antibiotics unless there are signs of spreading infection, systemic complications, or for an immunocompromised patient if signs of necrotizing disease. Advise the patient to seek urgent dental care as soon as possible within 24 hours.
Subsequent Care
Necrotizing periodontal disease: Necrotizing gingivitis (NG: relating to lesions limited to gingival tissue) and Necrotizing periodontitis (NP: where loss of attachment occurred). Consider: Scaling teeth as effectively as symptoms allow. Local anaesthesia may be required. Prescribing chemical plaque control (hydrogen Peroxide and 0.2% chlorhexidine mouthwash). Arranging appropriate therapy with a hygienist, dentist, or periodontist. Giving Oral Hygiene Instruction and, if appropriate, smoking cessation advice.
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Periodontal Abscess Consider: Incision and drainage, if possible. Scaling teeth as effectively as symptoms allow. Local anaesthesia may be required. Prescribing chemical plaque control (hydrogen peroxide and 0.2% chlorhexidine mouthwash). Arranging appropriate therapy with hygienist, dentist or periodontist. Extraction.
Perio-endo lesions: Tend to be associated with a single tooth leading to abscess formation. Consider: Root canal treatment or retreatment. Scaling teeth as effectively as symptoms allow. Local anaesthesia may be required. Prescribing chemical plaque control (hydrogen peroxide and chlorhexidine mouthwash). Arranging appropriate therapy with a hygienist, dentist or periodontist.
References American Academy of Periodontology. Parameter on acute periodontal diseases. Journal of Periodontogy 2000; 71 (5 Suppl): 8636. Chapple ILC, Gilbert. Understanding periodontal diseases: assessment and diagnostic procedures in practice. London: Quintessence Publishing, 2002. Needleman I, Giedrys-Leeper E (editors). Young practitioners guide to periodontology. Bubwith: British Society of Periodontology, 2011. Sutherland S, Matthews DC. Emergency management of acute apical periodontitis in the permanent dentition: a systematic review of the literature. Journal of the Canadian Dental Association 2003; 69: 660. Herrera D, Roldan S, Sanz M. The periodontal abscess: a review. Journal of Clinical Periodontology 2000; 27: 377-86.
Initial management
Gently rinse the mouth once with warm (not hot) water to wash out excess blood. Advise the patient to place a rolled up piece of cotton or a gauze swab moistened with saline or water over the socket and to bite firmly on it. Maintain the pressure for 20 minutes before checking whether the bleeding has stopped. 19
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If necessary, repeat once. If the patient is taking anticoagulant medication send the patient for immediate dental care via NHS 24 ideally within 1 hour. After the bleeding has stopped, advise the patient to avoid drinking alcohol, smoking or exercising for 24 hours and to avoid disturbing the blood clot. If the bleeding fails to stop and is severe, send the patient immediately to emergency medical care via NHS 24. If the bleeding fails to stop, but is not severe, send the patient for immediate dental care via NHS 24 ideally within 1 hour.
Subsequent Care
If application of pressure does not work, find the source of the bleeding. Consider: Applying a haemostatic dressing to the socket (e.g. oxidised cellulose such as Surgicell or haemocollagene sponge). Suturing the wound to achieve good soft-tissue closure and/or to stabilize the socket edges.
If the patient is a child, consider referral to a specialist to investigate underlying pathology. Do not prescribe antibiotics unless there are signs of spreading infection, systemic complications, or for an immunocompromised patient. References SDCEP. Emergency dental care: dental clinical guidance. Dundee: Scottish Dental Clinical Effectiveness Programme, 2007 (www.sdcep.org.uk/index.aspx?o=2335). Cork Emergency Medicine. Post extraction dental ENT/Dental/post_extraction_haemorrhage.html ). haemorrhage (http://handbook.muh.ie/HE-
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Initial management
Determine if the airway is compromised. Airway compromised: The patient is unable to swallow their own saliva or they are unable to push their tongue forward out of their mouth). Send the patient immediately to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Airway not compromised For adults: Recommend analgesia (see Appendix 2). Do not prescribe antibiotics unless there are signs of spreading infection, systemic complications, or for an immunocompromised patient. Advise the patient to rinse their mouth with 0.2% chlorhexidine mouthwash. Advise the patient to seek urgent dental care as soon as possible within 24 hours. For children: Advise analgesia, soft tooth brushing around affected area and rinsing the mouth after food.
Subsequent Care
For adults, consider: Ultrasonic scaling and/or debridement to remove any foreign body lodged around the partially erupted tooth, under local anaesthesia, where possible. Irrigating under damaged tissue with 0.2% chlorhexidine. Extracting the tooth, if there are repeated episodes of pericoronitis associated with the same tooth. Extracting or adjusting an opposing tooth, where there is trauma to the inflamed operculum, if the position of the tooth suggests that it is unlikely to achieve function in future.
References Chestnutt IG, Gibson J. Clinical Dentistry, 3rd edition. Edinburgh: Churchill Livingstone, 2007. SDCEP. Drug prescribing for dentistry: dental clinical guidance, 2nd edition. Dundee: Scottish Dental Clinical Effectiveness Programme; 2011 (www.sdcep.org.uk/index.aspx?o=2334). NICE. Guidance on the extraction of wisdom teeth. www.nice.org.uk, 2000.
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Initial management
Recommend analgesia (see Appendix 2). Advise the patient to avoid smoking and maintain good oral hygiene. Advise the patient to seek urgent dental care as soon as possible within 24 hours.
Subsequent Care
Consider: irrigating with 0.2% chlorhexidine*. applying a suitable material to dress the socket, e.g. Alvogyl.
Do not prescribe antibiotics unless there are signs of spreading infection, systemic complications, or for an immunocompromised patient. * Note that chlorhexidine has been reported as a very rare but potentially serious cause of allergic reaction when used for dry socket irrigation. It should not be used if a patient has a possible history of allergic reaction to chlorhexidine. Dental teams should be fully trained in recognising and managing allergic reactions, including anaphylaxis. References: Chestnutt IG, Gibson J. Clinical Dentistry, 3rd edition. Edinburgh: Churchill Livingstone, 2007. Halab D, Escobar J, Muoz C, Uribe S. Logistic Regression Analysis of Risk Factors for the Development of Alveolar Osteitis. J Oral Maxillofac Surg. 2012 (Epub ahead of print). Kolokythas A, Olech E, Miloro M. Alveolar osteitis: a comprehensive review of concepts and controversies. International Journal of Dentistry 2010; doi:10.1155/2010/249073. Mitchell L, Mitchell DA, McCaul. Oxford handbook of clinical dentistry, 5th edition. Oxford: Oxford University Press, 2009. Noroozi AR, Philbert RF. Modern concepts in understanding and management of the dry socketsyndrome: comprehensive review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 30-35. Medicines and Healthcare products Regulatory Agency. Drug safety update: Chlorhexidine: reminder of potential for hypersensitivity 2012 www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/CON140701
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Loose
or
Displaced
Tooth
Fragments
and
Initial management
If it is known or suspected that the patient has inhaled a piece of tooth, filling or restoration, send the patient immediately to emergency medical care via NHS 24. If the patient has an open cavity or fractured tooth, either provide a temporary dressing or advise the patient to use an emergency temporary repair kit which can be purchased at a pharmacy. Recommend analgesia (see Analgesic Prescribing section). If the painful symptoms are not relieved (see Appendix 2), advise the patient to seek urgent dental care as soon as possible within 24 hours. If pain is relieved or is not a significant component, advise the patient to seek prompt dental care within 7 days.
Subsequent Care
If tooth fragments or fillings, consider: Smoothing any rough edge, removing any loose or displaced tooth fragments or defective fillings. Providing a temporary palliative dressing or permanent filling. Pulp therapy (direct pulp cap, pulpotomy or root canal treatment) if fracture involves the pulp. Extracting if the tooth is not restorable. Recementing the restoration with a temporary or permanent cement, depending on the integrity of the tooth beneath and whether a new restoration is needed. Providing temporary coverage. Making permanent replacements. Providing a new crown for a primary tooth.
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Initial management
Do not examine with ungloved hands because of potential infection risk with viral ulcers. Determine how long the ulceration has been present. Present 3 weeks or more Refer the patient via the local rapid access pathway to investigate potential dysplasia or malignancy or to urgent medical care as soon as possible within 24 hours. Less than 3 weeks Determine whether: this is a single episode or recurrent the patient has an underlying medical condition or is systemically unwell one or multiple ulcers are present there has been trauma from an adjacent tooth or appliance or ill-fitting denture there has been recent dental treatment with local anaesthetic.
If ulceration is recurrent and self-limiting, advise the patient to use 0.2% chlorhexidine mouthwash* and to seek prompt dental care within 7 days. For children, recommend analgesia, soft diet and advise that ulcers are likely to resolve within 1-2 weeks.
If the patient has an underlying medical condition that might be the cause of the ulcer(s), advise them to seek urgent medical care as soon as possible within 24 hours from a general medical practitioner. When there are multiple ulcers present, advise the patient to see a dentist within 7 days. However, if the patient is also systemically unwell, advise them to seek urgent medical care as soon as possible within 24 hours from a general medical practitioner. If ulceration is due to ill-fitting dentures, advise the patient to use 0.2% chlorhexidine mouthwash*, to keep dentures out where possible and to seek prompt dental care within 7 days (also refer to Section 3.9). 24
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If there has been trauma from an adjacent tooth or orthodontic appliance, advise the patient to seek prompt dental care within 7 days (also refer to Section 3.10). If ulceration is likely to be due to trauma to anaesthetised tissue following recent treatment using local anaesthesia, advise the patient to avoid smoking, drinking hot liquids and biting the cheek or lip, and to see a dentist only if symptoms persist for 7 days. If a single ulcer appears not to have been caused by trauma, advise the patient to use 0.2% chlorhexidine mouthwash* until symptoms resolve or if the ulcer fails to heal within a week, to see a dentist within 7 days. Do not prescribe antibiotics unless there are signs of spreading infection, systemic complications, or for an immunocompromised patient. In all of the above cases, recommend analgesia, including prescription of topical analgesics (e.g. benzydamine oromucosal spray, see Appendix 2 ). * Chlorhexidine mouthwash is not suitable for children under 7 years old.
Subsequent Care
Consider: Fixing ill-fitting dentures if appropriate. Prescribing a topical steroid. Referring to the local rapid access pathway to investigate potential dysplasia or malignancy if symptoms persist. Referral to a dermatologist or an oral medicine specialist if vesiculobullous disorder is suspected.
In cases of primary herpetic gingivostamotatitis or herpes zoster infection, if the symptoms are severe or the patient is immunocompromised, consider prescribing antiviral agents (acyclovir or penciclovir), ideally in the early stages. Refer to a general medical practitioner if the patient has an underlying medical condition and is receiving a drug that may be the cause of ulceration. References Mitchell L, Mitchell DA, McCaul L. Oxford Handbook of Clinical Dentistry, 5th edition. Oxford: Oxford University Press 2009. Scully C, Shotts R. Mouth ulcers and other causes of orofacial soreness and pain. BMJ 2000; 321: 1625. Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med 2007; 36(10): 575-80.
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Initial management
Determine if the patient is in need of emergency medical attention. Patient in need of emergency medical attention: Signs of stroke, e.g. facial weakness or distortion, arm weakness, speech problems; rapid onset of these symptoms (F.A.S.T). Send the patient immediately to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Not in need of urgent medical attention Recommend analgesia (see Appendix 2). Advise the patient to remove their denture to ease discomfort. If the patient experienced discomfort after having the denture fitted following tooth extraction, advise the patient to return to dentist who fitted the denture. Advise the patient to seek prompt dental care within 7 days.
Subsequent Care
Consider: Providing temporary relining of dentures. Making new dentures. Referring to local rapid access pathway to investigate potential malignancy.
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March 2012
Initial management
If it is known or suspected that the patient has inhaled or ingested parts of a fractured appliance or the airway is compromised, send the patient immediately to emergency medical care via NHS 24. Remove any removable components of the fractured appliance. Apply malleable wax firmly onto any sharp, non-removable parts of the appliance causing trauma to the oral soft tissues. This may be orthodontic wax, or as a first-aid measure, the soft wax used to wrap cheeses can be moulded between fingers to form a soft ball (ensure that the patient does not have any allergy to dairy products before doing this). Advise the patient to seek prompt dental care within 7 days.
Subsequent Care
Consider: Removing or trimming loose or displaced arch wire of a fixed appliance. Adjusting or removing any fractured or distorted clasps or other wire components of a removable appliance. Trimming and smoothing any sharp sections of the acrylic base-plate of a removable appliance.
3.11 Sinusitis
Brief description of condition
Sinusitis, also known as rhinosinusitis, refers to inflamed sinuses, almost always accompanied by inflamed adjacent mucosa. The most common trigger is a viral upper respiratory tract infection. Sinusitis is a generally self-limiting condition that has an average duration of 2.5 weeks. Only around 2% of sinusitis cases are complicated by bacterial infections. Toothache arising from upper posterior teeth can be difficult to distinguish from sinusitis.
March 2012
Symptoms that worsen or persist after a week or are severe, particularly when accompanied by fever, fatigue or purulent discharge, possibly indicate bacterial infection.
Initial management
Recommend analgesia (see Appendix 2). If there are no signs of bacterial infection: Advise the patient to use steam inhalation (though due to risk of scalding this is not recommended for children). Advise the patient to see a general medical practitioner if symptoms worsen or last for more than a week.
If bacterial infection is present: Prescribe antibiotics (see SDCEP Drug Prescribing guidance). Consider prescribing oral corticosteroids as an adjunct to antibiotics in symptom relief.
Subsequent Care
Advise the patient to see a general medical practitioner if symptoms worsen or persist. References Ahovuo-Saloranta A, Rautakorpi UM, Borisenko OV, Liira H, Williams JW, Makela M. Antibiotics for acute maxillary sinusitis. Cochrane Database of Systematic Reviews 2008, Issue 2.Art.No.:CD000243. DOI:10.1002/14651858.CD000243.pub2. Ah-See KW, Evans AS. Sinusitis and its management. BMJ 2007; 334: 358-361. Garbutt JM, Banister C, Spitznagel E, Piccirillo JF. Amoxicillin for acute rhinosinusitis: a randomized controlled trial. JAMA 2012; 307(7): 685-92. SDCEP. Drug prescribing for dentistry: dental clinical guidance, 2nd edition. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011 (www.sdcep.org.uk/index.aspx?o=2334). Scully C. Medical problems in dentistry, 6th edition. Edinburgh: Churchill Livingstone, 2010. Shaikh N, Wald ER, Pi M. Decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Cochrane Database of Systematic Reviews 2010, Issue 12. Art. No.CD007909. DOI:10.1002/14651858.CD007909.pub2. Venekamp RP, Thompson MJ, Hayward G, Heneghan CJ, Del Mar CB, Perera R, Glasziou PP, Rovers MM. Systemic corticosteroids for acute sinusitis. Cochrane Database of Systematic Reviews 2011, Issue 12. Art. No.: CD008115. DOI: 10.1002/14651858.CD008115.pub2. Zalmanovici Trestioreanu A, Yaphe J. Intranasal steroids for acute sinusitis. Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD005149. DOI: 10.1002/14651858.CD005149.pub3.
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Initial management
Determine if the patient has a salivary gland obstruction or infection, which may represent or be associated with systemic sepsis. Infection: Acute gland pain or acute episode of chronic persistent gland pain, (does not fluctuate with meal times), erythema, severe symptoms, systemically unwell, bilateral or unilateral parotid swelling with fever (this also may be associated with mumps*). Recommend analgesia (see Appendix 2). Advise the patient to seek urgent medical care as soon as possible within 24 hours. * If the patient is young (e.g. less than 21 years) and experiences bilateral or unilateral parotid swelling, is systematically unwell and has low grade pyrexia, the patient may have mumps. Prescribe analgesia. Advise the patient to avoid spread of infection by staying at home. Refer to general medical practitioner for urgent medical care as soon as possible within 24 hours (notifiable disease). Obstruction without infection (major salivary glands): Intermittent pain and swelling, typically within an hour of meal times, then subsiding without erythema or fever. Recommend analgesia (see Appendix 2). Advise the patient to drink plenty of fluids if experiencing dry mouth. Obstruction without infection (minor salivary glands): Usually a small localised swelling as a result of trauma (mucocele) that often discharges spontaneously. Advise the patient to see a dentist within 7 days. If systemically unwell or there is a history of diabetes, advise the patient to seek urgent medical care as soon as possible within 24 hours. Otherwise, advise the patient to seek urgent dental care as soon as possible within 24 hours.
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Subsequent Care
Refer to an oral and maxillofacial surgeon if symptoms persist. If additional symptoms emerge (e.g. enlarging mass, facial weakness) refer the patient to urgent care as soon as possible within 24 hours from an oral and maxillofacial surgeon. Consider investigating dry mouth with blood tests. Consider surgical removal of persistent mucoceles or referral to an oral and maxillofacial surgeon
Initial management
Determine if there is need of emergency medical attention. Patient in need of emergency medical attention: Signs of stroke, e.g. facial weakness or distortion, arm weakness, speech problems; rapid onset of these symptoms (F.A.S.T). Send the patient immediately to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Patient not in need of emergency medical attention Protect the eye with a patch, eye lubricants, and possibly tape eyelids closed at night. Advise the patient to seek urgent medical care as soon as possible within 24 hours. Prescribe prednisolone (25 mg per day for 10 days) if within the first 72 hours of onset.
Subsequent Care
Refer the patient to general medical practitioner for onward referral to a specialist, if required.
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References Chen N, Zhou M, He L, Zhou D, Li N. Acupuncture for Bells palsy. Cochrane Database of Systematic Reviews 2010, Issue 8. Art. No.: CD002914. Lockhart P, Daly F, Pikethly M, Comerford N, Sullivan F. Antiviral treatment for Bells palsy (idiopathic facial paralysis). Cochrane Database of Systematic Reviews 2009, Issue 4. Art No.:CD001869. McAllister K, Walker D, Donnan PT, Swan I. Surgical interventions for the early management of Bells palsy. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD007468. Salinas RA, Alvarez G, Daly F, Ferreira J. Corticosteroids for Bells palsy (idiopathic facial paralysis). Cochrane Database of Systematic Reviews 2010, Issue 3. Art No.:CD001942. Sullivan FM, Swan IRC, Donnan PT, Morrison JM, Smith BH, McKinstry B, Davenport RJ, Vale LD, Clarkson JE et al. Early treatment with prednisolone or acyclovir in Bells Palsy. New England Journal of Medicine 2007; 357: 1598-607.
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March 2012
Initial management
Determine if the patient is in need of urgent medical attention: Patient is in need or emergency medical attention: bleeding is severe and will not stop within 15-30 minutes; if there has been significant facial trauma or if the patient has had a head injury or loss of consciousness; inhalation of tooth or tooth fragment. Send the patient to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Be aware of risk of cervical spine injury in deciding whether to move a patient. Patient NOT in need of emergency medical attention. Clean the affected area by rinsing gently with mild antiseptic and if foreign object(s) are present in the mouth, remove them. Apply ice packs to soft tissue injury and swelling. Apply digital pressure to stop any bleeding. (i) DENTO-ALVEOLAR INJURIES If a permanent (NOT primary) tooth has been knocked out, advise the patient to see a dentist within the hour and follow this procedure: Handle the tooth by its crown (the white part), avoid touching the root. If the tooth is dirty, wash it briefly (10 seconds) under cold running water. If it is feasible, replant the tooth in its socket and then bite gently on a handkerchief to hold it in position. If this is not feasible, store the tooth for transportation to the dentist in milk (not water). Alternatively transport the tooth in the mouth, keeping it between molars and the inside of the cheek. Note that primary teeth should not be replanted.
If a permanent tooth (or teeth) has been moved out of its usual position, advise the patient to see a dentist for assessment within 24 hours. If a primary tooth (or teeth) has been displaced, advise the patient to seek prompt dental care within 7 days. Advise the parent/carer to alter the childs diet to include soft food. If a permanent tooth fracture involves the dental pulp, advise the patient to seek urgent dental care as soon as possible within 24 hours. If the patient is a child or is in severe pain, then consider referral for immediate dental care via NHS 24 ideally within 1 hour. If Calcium Hydroxide paste is available this may be used to cover the exposed dental pulp as a first aid measure. First apply a small amount of local anaesthetic with a swab and dry gently. Then apply the paste. If a permanent tooth fracture involves only enamel and dentine, advise the patient to use desensitising toothpaste on the exposed dentine as a first aid measure and to see a dentist for assessment within 24 hours. Consider recommending analgesia (see Appendix 2). Do not prescribe antibiotics. (ii) MAXILLO-FACIAL FRACTURES AND SOFT TISSUE INJURIES If a bony fracture is suspected, send the patient to emergency medical care via NHS 24. Do not prescribe antibiotics at the initial assessment. If the patient has lacerations inside the mouth that: involve the attached gingival (hard gum) tissue and are greater than ~1 cm in length; involve the outside of the lip (greater than ~1 cm in length) or cross the vermillion border on to the facial skin;
send the patient for immediate dental care via NHS 24 ideally within 1 hour. Otherwise, further operative care is not usually required, but advise the patient to maintain good oral hygiene and to use 0.2% chlorhexidine mouthwash*. * Chlorhexidine mouthwash is not suitable for children under 7 years old. 32
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Subsequent care
Subsequent care depends on the diagnosed condition and whether the tooth is primary or permanent. Refer to the Dental Trauma Guide www.dentaltraumaguide.org for detailed advice on the management of a wide range of injuries and conditions that result from trauma. (i) DENTO-ALVEOLAR INJURIES Consider: Radiographic examination for complete diagnosis. Addressing permanent tooth fractures or loss of permanent tooth structure by restoring the tooth or bonding the tooth fragment to the tooth. Pulp capping, partial pulpotomy or, particularly for a primary tooth, extraction. Applying a flexible splint for up to 1-4 weeks, after replanting a permanent tooth. Instructing the patient to adhere to a soft food diet for 7 days and for a longer period if primary tooth is involved.
Advise the patient to maintain good oral hygiene. Follow local child protection procedures if there is any suspicion that this was a non-accidental injury to the child, taking into consideration the behaviour of the patient and the parent/carer. (ii) MAXILLO-FACIAL FRACTURES AND SOFT TISSUE INJURIES These conditions require specialist care and are normally managed by oral and maxillofacial surgery teams.
References Advanced Trauma Life Support (ATLS) guideline (www.gpnotebook.co.uk/simplepage.cfm?ID=1509556199). Advanced Trauma Life Support. In: Mitchell L, Mitchell DA, McCaul L. Oxford Handbook of Clinical Dentistry, 5th edition. Oxford: Oxford University Press 2009; pp452-453. Oregon State DOC Health Services. Dental Protocol for Oral Lacerations (www.oregon.gov/DOC/OPS/HESVC/docs/protocols/Dental_protocols/Oral_Lacerations_Level_2.pdf?ga =t). Flores MT, Andersson L, Andreason JO, Bakland LK, Malmgren B, Bourguignon C, DiAngelis A, Hicks L, Sigurdsson A, Trope M, Tsukiboshi M, von Arx T. Guidelines for the management of traumatic dental injuries. I. fractures and luxations of permanent teeth. Dental Traumatology 2007; 23: 66-71. Flores MT, Andersson L, Andreason JO, Bakland LK, Malmgren B, Bourguignon C, DiAngelis A, Hicks L, Sigurdsson A, Trope M, Tsukiboshi M, von Arx T. Guidelines for the management of traumatic dental injuries. II. Avulsion of permanent teeth. Dental Traumatology 2007; 23: 130-136. Flores MT, Malmgren B, Andersson L, Andreason JO, Bakland LK, Barnett F, Bourguignon C, DiAngelis A, Hicks L, Sigurdsson A, Trope M, Tsukiboshi M, von Arx T. Guidelines for the management of traumatic dental injuries. III. Primary teeth. Dental Traumatology 2007; 23: 196-202. Harris J, Sidebotham P, Welbury R, Townsend R, Green M, Goodwin J. Child protection and the dental team: an introduction to safeguarding children in dental practice. Sheffield: Committee of Postgraduate Dental Deans and Directors; 2006 (www.cpdt.org.uk). Kullman L, Sane MA. Guidelines for dental radiography immediately after a dento-alveolar trauma, a systematic literature review. Dental Traumatology 2011: doi: 10.1111/j.1600-9657.2011.01099.x. Maguire S, Hunter B, Hunter L, Sibert JR, Mann M, Kemp AM et al. Diagnosing abuse: a systematic review of torn frenum and other intra-oral injuries. Archives of Disease in Childhood 2007;92:1113-7. The Dental Trauma Guide. www.dentaltraumaguide.org Welbury R, Gregg T. Managing dental trauma in practice. London: Quintessence Publishing, 2006.
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For dislocated jaw: Unable to move jaw Jaw is displaced in open position
Initial management
Dislocated jaw: Send the patient to emergency medical care via NHS 24. Recommend analgesia (see Appendix 2). Other temperomandibular joint conditions: Recommend analgesic/anti-inflammatory drugs (see Appendix 2). Consider both the benefits and potential harms of prescribing a short course of diazepam to relax muscles (for adults only see Appendix 2). Advise the patient to use local heat packs or ice packs to relieve the symptoms. Advise the patient to have a soft diet, to avoid chewing gum and to rest their jaw. Advise the patient to seek prompt dental care within 7 days.
Subsequent Care
Consider making an occlusal splint for the patient. Monitor symptoms in follow-up appointment(s). Consider referring the patient for specialist opinion if the above measures do not improve symptoms. References: Al-Ani MZ, Davies SJ, Gray RJM, Sloan P, Glenny AM. Stabilisation splint therapy for temporomandibular pain dysfunction syndrome. Cochrane Database of Systematic Reviews 2004, Issue 1. Art. No.: CD002778. DOI: 10.1002/14651858.CD002778.pub2. Chestnutt IG, Gibson J. Clinical Dentistry, 3rd edition. Edinburgh: Churchill Livingstone, 2007.
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Guo C, Shi Z, Revington P. Arthrocentesis and lavage for treating temporomandibular joint disorders. Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD004973. DOI: 10.1002/14651858.CD004973.pub2. Koh H, Robinson P. Occlusal adjustment for treating and preventing temporomandibular joint disorders. Cochrane Database of Systematic Reviews 2003, Issue 1. Art. No.: CD003812. DOI: 10.1002/14651858.CD003812. List T, Axelsson S. Management of TMD: evidence from systematic reviews and meta-analyses. Journal of Oral Rehabilitation 2010; 430-51. Mujakperuo HR, Watson M, Morrison R, Macfarlane TV. Pharmacological interventions for pain in patients with temporomandibular disorders. Cochrane Database of Systematic Reviews 2010, Issue 10. Art. No.: CD004715. DOI: 10.1002/14651858.CD004715.pub2. SDCEP. Drug prescribing for dentistry: dental clinical guidance, 2nd edition. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011 (www.sdcep.org.uk/index.aspx?o=2334).
Initial management
If a patient is using a corticosteroid inhaler, in the first instance, advise them to rinse their mouth with water or brush their teeth immediately after using the inhaler. For superficial infections, prescribe systemic fluconazole (one 50 mg capsule per day for seven days) or miconazole oromucosal gel for topical application; Note that fluconazole interacts with many drugs. If fluconazole or miconazole are contraindicated, prescribe nystatin (1 ml of 100,000 units/ml oral suspension four times daily for seven days).
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Subsequent Care
Monitor symptoms at follow-up appointments. If the patient does not respond to appropriate local measures and a course of drug treatment, or there is no identifiable cause, refer the patient to the patients general medical practitioner for further investigation or to a dental specialist. Fungal infections in immunocompromised patients with serious systemic disease require assessment by the patients general medical practitioner. References: SDCEP. Drug prescribing for dentistry: dental clinical guidance, 2nd edition. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011 (www.sdcep.org.uk/index.aspx?o=2334).
Initial management
Determine if the airway is compromised. Airway is compromised: Speech swallowing or breathing are restricted, the patient is unable to swallow their own saliva or they are unable to push their tongue forward out of their mouth. Send the patient immediately to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Airway is not compromised: If a lump has been present unchanged for weeks, advise the patient to seek prompt dental care within 7 days. If the swelling is ulcerated or has begun to increase in size rapidly, advise the patient to seek urgent dental or medical care as soon as possible within 24 hours. Determine how long the altered appearance has been present. More than 3 weeks: refer the patient via the local rapid access pathway to investigate potential dysplasia or malignancy or to a doctor or dentist within 24 hours. Less than 3 weeks: advise the patient to see a dentist within 7 days. 36
March 2012
Subsequent Care
Monitor symptoms at follow-up appointments. Record altered appearance on a mouth map or with a digital camera. Consider referral to an oral and maxillofacial surgeon or an oral medicine specialist. For red and white patches and pigmented areas, if lesion does not resolve in 3 weeks refer the patient via the local rapid access pathway to investigate potential dysplasia or malignancy or to doctor or dentist within 24 hours.
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March 2012
Initial management
Recommend analgesia (see Appendix 2). Prescribe Carbamazepine (100mg two or three times per day) without delay. Advise the patient to seek urgent medical care within 24 hours from a general medical practitioner.
Subsequent Care
Monitor symptoms and response to medication at follow-up appointments and titrate the dose. Monitor for adverse effects by ordering a full blood count and liver function tests. If unresponsive or intolerant of drug therapy, refer to a specialist for further assessment. References: Chestnutt IG, Gibson J. Clinical Dentistry, 3rd edition. Edinburgh: Churchill Livingstone, 2007. NHS Inform. www.nhsinform.co.uk SDCEP. Drug prescribing for dentistry: dental clinical guidance, 2nd edition. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011 (www.sdcep.org.uk/index.aspx?o=2334). Yang M, Zhou M, He L, Chen N, Zakrzewska JM. Non-antiepileptic drugs for trigeminal neuralgia. Cochrane Database of Systematic Reviews 2011, Issue 1. Art. No.: CD004029. DOI: 10.1002/14651858.CD004029.pub3. Zakrzewska JM, AkramH. Neurosurgical interventions for the treatment of classical trigeminal neuralgia. Cochrane Database of Systematic Reviews 2011, Issue 9. Art. No.: CD007312. DOI: 10.1002/14651858.CD007312.pub2.
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Initial management
Determine if there is need of emergency medical attention. Patient in need of emergency medical attention: Signs of stroke, e.g. facial weakness or distortion, arm weakness, speech problems; rapid onset of these symptoms (F.A.S.T). Send the patient immediately to emergency medical care via NHS 24 or if the patient is not safe to move call 999. Patient not in need of emergency medical attention: If the patient has recently had an injection, extraction, surgery, botox treatment or treatment for trauma, advise the patient to contact the treatment provider within 7 days, or earlier if the symptoms worsen. Otherwise, advise them to see seek urgent medical care within 24 hours from a general medical practitioner. If there are signs of spreading infection, prescribe antibiotics.
Subsequent Care
Treat the underlying cause, if known. Monitor symptoms at follow-up appointments and refer to a specialist if required. References Lockhart PB, Meechan JG, Nunn J (editors). Dental care of the medically complex patients, 5th edition. Wright (An imprint of Elsevier Science Limited), 2004.
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3.20 Osteonecrosis
Brief description of condition
Exposed avascular bone. Patients taking a bisphosphonate drug (e.g for osteoporosis) may be at increased risk of developing osteonecrosis of the jaw.
Initial management
Recommend analgesia (see Appendix 2). Advise the patient to rinse their mouth with 0.2% chlorhexidine mouthwash. If of recent onset, advise the patient to see urgent dental or medical care as soon as possible within 24 hours for assessment. If chronic, ensure review within 7 days by a doctor or dentist. Do not prescribe antibiotics unless there is a discharge.
Subsequent Care
Minimise the need for extractions and avoid minor oral surgery. Refer to an oral medicine specialist or an oral and maxillofacial surgeon to establish diagnosis and treatment that may include: identifying relevant systemic factors, bisphosphonates, other fixed drug eruptions, history of radiotherapy. investigating potential malignancy. surgical debridement and tension free closure. medical management or reconstruction with vascularised bone. liaison with a general medical practitioner or a specialist to replace associated medication, e.g. bisphosphonates.
References SDCEP. Oral health management of patients prescribed bisphosphonates: clinical guidance. Dundee: Scottish Clinical Effectiveness Programme 2011 (www.sdcep.org.uk/index.aspx?o=3017). Moretti F, Pelliccioni GA, Montebugnoli L, Marchetti C. A prospective clinical trial for assessing the efficacy of a minimally invasive protocol in patients with bisphosphonate-associated osteonecrosis of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 777-82.
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3.21 Peri-implantitis
Brief description of condition
Inflammation affecting the soft and hard tissues around implants, leading to loss of bone support.
Initial management
Recommend analgesia (see Appendix 2). Do not prescribe antibiotics unless there are signs of spreading infection, systemic complications, or for an immunocompromised patient. Recommend good oral hygiene. Advise the patient to see a dentist within 7 days or within 24 hours if analgesia is ineffective.
Subsequent Care
Assess the patients progress including radiographic assessment to evaluate bone loss and monitor the outcome of treatment. Give appropriate oral hygiene instruction. Consider non-surgical debridement with carbon fibre or plastic curettes and irrigating the pocket with 0.2% chlorhexidine. Consider surgical debridement and implant decontamination with saline or 0.2% chlorhexidine. In severe cases, consider regenerative surgery with barrier membranes with or without autogenous bone grafts or bone substitute or surgical removal of the implant. References: Heitz-Mayfield LJ. Diagnosis and management of peri-implant diseases. Aust Dent J. 2008 Jun;53 Suppl 1:S43-8. Lang NP, Berglundh T on Behalf of Working Group 4 of the Seventh European Workshop on Periodontology: Periimplant diseases: where are we now? Consensus of the Seventh European Workshop on Periodontology. Journal of Clinical Periodontology 2011: 38 (Suppl. 11): 178-181. doi: 10.1111/j.1600-051X.2010.01674.x.
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Initial management
Refer the patient to urgent medical care as soon as possible within 24 hours because high dose cotrico-steriod prescription without delay is likely to be required.
Subsequent Care
Prescribe systemic cortico-steroids without delay (prednisolone, 60mg daily). Order blood tests without delay to assess C-reactive protein, plasma viscosity or erythrocyte sedimentation rate (ESR) before the patient starts taking prednisolone. Monitor symptoms and response to treatment at follow-up appointments to assess to determine further prednisolone dose. References: Chestnutt IG, Gibson J. Clinical Dentistry, 3rd edition. Edinburgh: Churchill Livingstone, 2007. Dasgupta B on behalf of the Giant Cell Arteritis Guideline Development Group. Concise guidance: diagnosis and management of giant cell arteritis. Clinical Medicine 2010; 10: 4: 381-6. Medscape. http://emedicine.medscape.com/article/1201429-overview Pub med www.ncbi.nlm.nih.gov/pubmedhealth
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Margaret Madden Charles Maran Avril Neilson Emma OKeefe Derek Richards David Ricketts Verena Toedtling Richard Welbury
Day time call handler, NHS Lothian Specialist in Periodontics, Edinburgh Dental Institute Consultant in Oral Surgery, Dundee Dental Hospital and School Specialty Registrar in Dental Public Health, NHS Fife Consultant in Dental Public Health, South East Scotland Professor of Cariology & Conservative Dentistry, Univerisity of Dundee Clinical Lecturer and Honorary Specialist Registrar in Oral Surgery at University of Manchester Professor of Paediatric Dentistry, University of Glasgow
March 2012
Systematic Reviews. This guidance is based on guidelines, systematic reviews and other published literature listed at the end of each subsection and the opinion of experts and experienced practitioners. A consultation draft of this guidance is sent to individuals and bodies with a specific interest in the management of patients with acute dental problems in a variety of healthcare settings, and to those involved in the organisation of dental services and dental education in Scotland. To obtain feedback from the end-users of the guidance, dentists, general medical practitioners and pharmacists in Scotland are notified that the consultation draft is available on the SDCEP website or on request, and invited to comment. Following completion of the consultation period, all comments will be reviewed and considered to inform further development of the guidance. Further information about the methodology used to develop this guidance will be available on our website: www.scottishdental.org/cep. Declarations of interest are made by all contributors to SDCEP. Details are available on request.
Steering Group
The Steering Group oversees all the activities of the SDCEP and includes representatives of each guidance development group and the dental institutions in Scotland.
Jeremy Bagg (Chairman) Graham Ball Jan Clarkson Tony Anderson Dafydd Evans Alice Miller Jim Newton Nigel Pitts Derek Richards Nigel Robb Mark Hector Alan Whittet David Wray Chairman of the National Dental Advisory Committee; Head of Glasgow Dental School and Professor of Clinical Microbiology, University of Glasgow Consultant in Dental Public Health, South East Scotland Director, Scottish Dental Clinical Effectiveness Programme; Programme Director, Professor of Clinical Effectiveness, University of Dundee Acting Clinical Director, Edinburgh Postgraduate Dental Institute Senior Lecturer and Consultant in Paediatric Dentistry, Dundee Dental Hospital and School, University of Dundee General Dental Practitioner, Duns, Borders; VT Adviser, NHS Education for Scotland Director of Aberdeen Dental School; Professor, University of Aberdeen Professor of Dental Health; Director, Dental Health Services Research Unit, University of Dundee Specialist Advisor to the Programme Development Team; Consultant in Dental Public Health, South East Scotland; Director of the Centre for Evidence-Based Dentistry, Oxford Reader and Honorary Consultant in Restorative Dentistry, School of Oral and Dental Sciences, University of Bristol Dean for Dentistry and Professor of Oral Health of Children, University of Dundee General Dental Practitioner, Longniddry; Dental Practice Adviser, NHS Lothian Professor of Oral Medicine, University of Glasgow Dental School
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Appendix 2 Analgesia
Providing Self-help Advice on Managing Dental Pain
The delivery of advice on managing dental pain requires suitable training. Give the patient the following advice on the use of self-help measures, including ibuprofen and/or paracetamol to relieve pain. Avoid stimuli that precipitate or worsen the pain such as hot or cold foods or cold air. Holding cooled water or crushed ice around the tooth can help some types of dental pain. Severe pain from the mouth or teeth sometimes feels worse when lying flat; therefore, try lying propped up as this might ease the pain. Use painkillers that have successfully provided pain relief for you in the past without adverse effects. Avoid taking aspirin as a painkiller if there is bleeding. Swallow tablets. Do not place tablets next to the affected area because this can damage the tissue. Remind the patient to follow the directions on the packet for dosage and advice on precautions in some medical conditions. For example, patients with asthma should avoid ibuprofen. Advise the patient to call back if the advice provided proves inadequate.
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Odontogenic Pain
For mild to moderate odontogenic or post-operative pain, an appropriate 5-day regimen is: Paracetamol Tablets, 500 mg Send: 40 tablets For children: Paracetamol Tablets or Soluble Tablets, 500 mg, or Oral Suspension*, 120 mg/5 ml or 250 mg/5 ml 6 months 2 years 2 4 years 4 6 years 6 - 8 years 8 - 10 years 10 - 18 years 120 mg four times daily (max. 4 doses in 24 hours) 180 mg four times daily (max. 4 doses in 24 hours) 240 mg four times daily (max. 4 doses in 24 hours) 250 mg four times daily (max. 4 doses in 24 hours) 375 mg four times daily (max. 4 doses in 24 hours) 500 mg four times daily (max. 4 doses in 24 hours)
Label:
NB: Advise patient that paracetamol can be taken at 4-hourly intervals but not to exceed the recommended daily dose (maximum of 4 g for adults). Overdose with paracetamol is dangerous because it can cause hepatic damage that is sometimes not apparent for 46 days; as little as 1015 g taken within 24 hours can cause severe hepatocellular necrosis. Transfer patients who have taken an overdose to hospital (for more information see the British National Formulary; www.bnf.org). Childrens doses are in line with the BNFC and also reflect guidance from MHRA on more exact paracetamol dosing for children. *Sugar-free preparation is available.
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For mild to moderate odontogenic, post-operative or inflammatory pain, an appropriate 5-day regimen is: Ibuprofen Tablets, 400 mg Send: Label: 20 tablets 1 tablet four times daily, preferably after food For children: Ibuprofen Oral Suspension, 100 mg/5 ml or ibuprofen tablets, 200 mg 6 months 1 year 14 years 47 years 710 years 1012 years 1218 years 50 mg four times daily, preferably after food 100 mg three times daily, preferably after food 150 mg three times daily, preferably after food 200 mg three times daily, preferably after food 300 mg three times daily, preferably after food 300400 mg four times daily, preferably after food
NB: In adults, the dose of ibuprofen can be increased, if necessary, to a maximum of 2.4 g daily. Avoid use in those with a hypersensitivity to aspirin or any other NSAID, including those in whom attacks of asthma, angioedema, urticaria or rhinitis have been precipitated by aspirin or any other NSAID. Avoid use in patients with previous or active peptic ulcer disease, unless a proton pump inhibitor is co-prescribed (see below), and use with caution in the elderly, patients with allergic disorders, pregnant women, nursing mothers, those taking oral anticoagulants such as warfarin, those with coagulation defects, those with an inherited bleeding disorder, and those with renal, cardiac or hepatic impairment. *Sugar-free preparation is available.
In cases where paracetamol or ibuprofen alone is not effective, both paracetamol and ibuprofen can be given alternately (i.e. ibuprofen can be taken first and then paracetamol 2 hours later, and so on, using the normal daily doses given in the prescription boxes above). This regimen controls ongoing pain and pyrexia without exceeding the recommended dose or frequency of administration for either drug.
For mild to moderate odontogenic or inflammatory pain, an appropriate 5-day regimen is: Aspirin Dispersible Tablets, 300 mg Send: 40 tablets For children: <16 years Do not use in children because, rarely, it can cause Reyes syndrome As for adults
Label:
16 years
NB: Advise patient that aspirin can be taken at 4-hourly intervals but not to exceed the recommended daily dose. In adults and children 16 years and over, up to 3 tablets (900 mg) can be given in one dose (maximum daily dose of 4 g). Do not prescribe aspirin following a dental extraction or other minor surgery. Avoid use in those with a known allergy to aspirin or hypersensitivity to aspirin or any other NSAID, including those in whom attacks of asthma, angioedema, urticaria or rhinitis have been precipitated by aspirin or any other NSAID. Avoid use in patients with previous or active peptic ulcer disease and use with caution in the elderly, patients with allergic disorders, pregnant women, nursing mothers, those taking oral anticoagulants such as warfarin, those with coagulation defects, those with an inherited bleeding disorder, and those with renal, cardiac or hepatic impairment. Aspirin is not licensed for use in children under 16 years (see Section 1.2).
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Diclofenac is also effective against moderate inflammatory or post-operative pain. An appropriate 5-day regimen is: Diclofenac Sodium Tablets, 50 mg Send: Label: 15 tablets 1 tablet three times daily For children: Not recommended for dental use in children
NB: Advise patient not to exceed the recommended daily dose (maximum of 150 mg). Avoid use in those with a hypersensitivity to aspirin or any other NSAID, including those in whom attacks of asthma, angioedema, urticaria or rhinitis have been precipitated by aspirin or any other NSAID. Avoid use in patients with previous or active peptic ulcer disease, unless a proton pump inhibitor is co-prescribed (see below), and use with caution in the elderly, patients with allergic disorders, pregnant women, nursing mothers, those taking oral anticoagulants such as warfarin, those with coagulation defects, those with an inherited bleeding disorder, and those with renal, cardiac or hepatic impairment. Diclofenac tablets are enteric coated and are therefore slower to act. Diclofenac tablets of >25 mg are not licensed for use in children.
In patients who have a history of previous or active peptic ulcer disease and require a NSAID for the treatment of odontogenic pain, an appropriate 5-day regimen to prevent gastric problems is: Lansoprazole Capsules, 15 mg Send: Label: 5 capsules 1 capsule once daily For children: Not licensed for children
NB: Use with caution in patients with liver disease, in pregnancy and in patients who are breast-feeding.
or
NB: Use with caution in patients with liver disease, in pregnancy and in patients who are breast-feeding.
Trigeminal Neuralgia If a patient with trigeminal neuralgia presents in primary care, control quickly by treatment with carbamazepine. A positive response confirms the diagnosis. Make an urgent referral to a specialist or the patients general medical practitioner for a full blood count and liver function tests to monitor for adverse effects, assess the response and titrate the dose. An appropriate 10-day regimen is: Carbamazepine Tablets, 100 mg Send: Label: 20 tablets 1 tablet twice daily For children: Not relevant for children
NB: Advise patient to space out doses as much as possible throughout the day. Carbamazepine has the potential to react with multiple other medicines; check appendix 1 of BNF for interactions. Carbamazepine can cause reversible blurring of vision, dizziness and unsteadiness (dose-related).
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Other Facial Pain Acute temporomandibular dysfunction might respond to analgesics such as ibuprofen or a short course of diazepam as a muscle relaxant. However, as benzodiazepines are addictive and susceptible to abuse only the minimum number of tablets required should be prescribed. An appropriate 5-day regimen is: Diazepam Tablets, 2 mg Send: Label: 15 tablets 1 tablet 3 times daily For children: Not recommended because it has an unpredictable effect in children
NB: The dose can be increased if necessary to 15 mg daily. Halve the adult dose for elderly or debilitated patients. Advise all patients that they should not drive.
Oral Ulceration Local analgesics cannot relieve pain continuously but are helpful in severe pain (e.g. major aphthae) to enable eating or sleeping. Lidocaine 5% ointment can be directly applied to the ulcer or lidocaine 10% solution, provided as a spray, can be applied to the ulcer using a cotton bud. Benzydamine hydrochloride mouthwash or spray can also reduce mucosal discomfort. An appropriate regimen is a choice of: Benzydamine Mouthwash, 0.15% Send: 300 ml For children: <12 years Not recommended for use because of local anaesthetic properties As for adults
Label:
12 years
NB: Advise patient that benzydamine mouthwash can be diluted with an equal volume of water if stinging occurs. Advise patient to spit out mouthwash after rinsing. The mouthwash is usually given for not more than 7 days.
or
Benzydamine Oromucosal Spray, 0.15% Send: Label: 30 ml 4 sprays onto affected area every 1 hours
For children: Benzydamine Oromucosal Spray, 0.15% 6 months 6 years 618 years 1 spray per 4 kg bodyweight (max. 4 sprays) every 1 hours 4 sprays every 1 hours
NB: In adults and children of 12 years and over, up to 8 sprays of benzydamine oromucosal spray can be applied at any one time.
or
Lidocaine Ointment, 5% Send: Label: 15 g Rub sparingly and gently on affected areas
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NB: Advise patient to take care with the application to avoid producing anaesthesia of the pharynx before meals as this might lead to choking.
or
Lidocaine Spray, 10% Send: Label: 50 ml Apply as necessary with a cotton bud For children: As for adults
NB: Advise patient to take care with the application to avoid producing anaesthesia of the pharynx before meals as this might lead to choking. Lidocaine Spray, 10%, is not licensed for oral ulceration.
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Table 1 Drug-related oral health side effects Symptoms Dry mouth Drugs potentially implicated Refer to Table 2 below Initial management Maintain good oral hygiene, and use fluoride mouthwash. Take frequent sips of cold water. Suck ice-cubes. Use sugar-free chewing gum to help stimulate saliva production. Limit caffeine and alcohol intake, which have a diuretic effect. Where lips are dry and/or cracked, apply lip balm or petroleum jelly. Drooling Anticholinesterases e.g. neostigmine, pyridostigmine Clozapine Pilocarpine Taste disturbance ACE inhibitors Aspirin Amiodarone Buprenorphine Carbimazole Chlorhexidine Clofibrate Ethambutol Griseofulvin Gold salts Imipramine Lithium carbonate Lincomycin Levodopa Metformin Metronidazole Penicillamine Reassure the patient of benign nature of the condition. If problem persists, advise patient to contact their GP. Advise patient to contact their GP. Subsequent care If dry mouth becomes troublesome or difficult to manage, artificial saliva products may be considered, for use as required. Patients are more susceptible to candidal infection, therefore consider treatment with an appropriate antifungal agent where necessary. If problem persists, advise patient to contact their GP.
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Gingival overgrowth
Oral ulceration
NSAID Nicorandil Beta blockers Methotrexate Cytotoxic drugs Sulphonamides Sulfasalazine Anticonvulsants (such as phenobarbital, phenytoin carbamazepine) Allopurinol Penicillin
Maintain good oral hygiene. Symptomatic relief can be obtained through use of chlorhexidine mouthwash or topical corticosteroids. if suspected ADR or blood dyscrasias, refer patient to their GP immediately.
If ulcer(s) have persisted beyond 10 days, or are severe or recurrent, advise patient to contact their GP.
Maintain good oral hygiene. Advise on use of antifungal oral gel. If candidal infection is severe, consider use of systemic antifungal agent. If patient using inhaled corticosteroids, advise rinsing their mouth and throat with water after use, and confirm good inhaler technique.
Reassure the patient of benign nature of the condition. Advise that condition will resolve once treatment has stopped.
Maintain good oral hygiene. Use of chlorhexidine mouthwash should not be limited to a few weeks only.
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If the nature of the condition is confirmed as drug-related i.e. nonmalignant, reassure the patient of benign nature of the condition. Advise patient to contact their GP.
Bishphosphonates
Advise patient on need to be vigilant for signs/ symptoms of condition. Where confirmed, and in absence of any infection, advise on use of analgesics +/- antiseptic mouthwashes (used twice a day). Where infection present, wound or pus samples must be taken (for sensitivity testing) before prescribing systemic antimicrobials in accordance with Health Board prescribing policy.
Discuss care of patient with their GP, and need for continued treatment with bisphosphonate. Consider need for surgical management.
Table 2 Drug groups known to cause symptoms of dry mouth Analgesics (opioid) Antidepressants (tricyclic) Antidepressants (SSRI) Antiemetics Anticonvulsants Antihistamines (sedating) Antimanic drugs Antimigraine drugs Antimuscarinic drugs CNS stimulants Parkinson's disease drugs Antipsychotics Antispasmodics Beta-blockers Diuretics e.g. Morphine, oxycodone e.g. Amitriptyline, clomipramine e.g. Citalopram, fluoxetine e.g. Hyoscine hydrobromide e.g. Carbamazepine, gabapentin e.g. Chlorphenamine, promethazine e.g. Lithium carbonate, lithium citrate e.g. Pizotifen, clonidine e.g. Orphenadrine, procyclidine, trihexyphenidyl, Ipratropium, tiotropium e.g. atomoxetine, methylphenidate e.g. Levodopa e.g. Clozapine, Olanzapine, phenothiazines e.g. Baclofen, Oxybutynin, solifenacin e.g. Atenolol, propranolol e.g. Furosemide
NB: Drug-induced dry mouth is often caused by the anticholinergic properties of drugs. The above drug groups are not a comprehensive list of drugs that are associated with dry mouth, as many other drugs can cause these symptoms.
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Appendix 3 References Data from manufacturers' summary of products monograph data (http://emc.medicines.org.uk). Joint National Formulary. British National Formulary no.62. Pharmaceutical Press, September 2011. Scully C, Kalantzis A. Oxford Handbook of Dental Patient Care, 2nd edition. Oxford: Oxford University Press, 2005. care - oral problems Management. Clinical Knowledge Summaries www.cks.nhs.uk/palliative_cancer_care_oral. Stillman P, Edwards C. Major illness or major disease? The clinical pharmacist in the community, 4th edition. London: Pharmaceutical Press, 2006. Meleti M, Vescovi P, Mooi WJ, et al. Pigmented lesions of the oral mucosa and perioral tissues: a flowchart for the diagnosis and some recommendations for the management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 105: 606-16. McLeod NMH, Patel V, Kusanale A, et al. Bisphosphonate osteonecrosis of the jaw: a literature review of UK policies versus international policies on the management of bisphosphonate osteonecrosis of the jaw. Br J Oral Maxillofac Surg 2011; 49: 335-42.
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