Agents Classified by The IARC Monographs

Agents Classified by the IARC Monographs, Volumes 1107
CAS No
Agent
026148-68-5
000083-32-9
025732-74-5
000075-07-0
000075-07-0
A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)
Acenaphthene
Acepyrene (3,4-dihydrocyclopenta[cd]pyrene)
Acetaldehyde
Acetaldehyde associated with consumption of alcoholic
beverages
Acetamide
Acetaminophen (see Paracetamol)
Aciclovir
Acid mists, strong inorganic
Acridine orange
Acriflavinium chloride
Acrolein
Acrylamide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Acrylic acid
Acrylic fibres
Acrylonitrile
Acrylonitrile-butadiene-styrene copolymers
Actinomycin D
Adriamycin
AF-2 [2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide]
Aflatoxins
Aflatoxin M1
Agaritine
Alcoholic beverages
Aldicarb
Aldrin
Allyl chloride
Allyl isothiocyanate
Allyl isovalerate
Alpha particles (see Radionuclides)
Aluminium production
000060-35-5
000103-90-2
059277-89-3
000494-38-2
008018-07-3
000107-02-8
000079-06-1
000079-10-7
000107-13-1
000050-76-0
023214-92-8
003688-53-7
001402-68-2
006795-23-9
002757-90-6
000116-06-3
000309-00-2
000107-05-1
000057-06-7
002835-39-4
Group
000915-67-3 Amaranth
004657-93-6 5-Aminoacenaphthene
Year
2B
3
3
2B
1
40, Sup 7
92
92
36, Sup 7, 71
100E
1987
2010
2010
1999
2012
2B
7, Sup 7, 71
1999
3
1
3
3
3
2A
76
54, 100F
16, Sup 7
13, Sup 7
63
60
2000
2012
1987
1987
1995
1994
3
3
2B
3
3
2A
19, Sup 7, 71
19, Sup 7
71
19, Sup 7
10, Sup 7
10, Sup 7
1999
1987
1999
1987
1987
1987
2B
1
2B
3
1
3
3
3
3
3
31, Sup 7
56, 82, 100F
56
31, Sup 7
44, 96, 100E
53
5, Sup 7
36, Sup 7, 71
73
36, Sup 7, 71
1987
2012
1993
1987
2012
1991
1987
1999
1999
1999
34, Sup 7,
100F
8, Sup 7
16, Sup 7
2012
1
3
3
Volume
1987
1987

CAS No
Agent
000117-79-3
000060-09-3
000097-56-3
000150-13-0
000092-67-1
2-Aminoanthraquinone
para-Aminoazobenzene
ortho-Aminoazotoluene
para-Aminobenzoic acid
4-Aminobiphenyl
3
2B
2B
3
1
000081-49-2
000082-28-0
000712-68-5
000099-57-0
000121-88-0
000119-34-6
000121-66-4
002432-99-7
000061-82-5
1-Amino-2,4-dibromoanthraquinone
1-Amino-2-methylanthraquinone
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
2-Amino-4-nitrophenol
2-Amino-5-nitrothiazole
11-Aminoundecanoic acid
Amitrole
(NB: Overall evaluation downgraded to Group 3 with
Ampicillin
Amsacrine
Androgenic (anabolic) steroids
Anaesthetics, volatile
Angelicin plus ultraviolet A radiation
Aniline
ortho-Anisidine
para-Anisidine
Anthanthrene
Anthracene
Anthranilic acid
Anthraquinone
Antimony trioxide
Antimony trisulfide
Apholate
para-Aramid fibrils
Aramite
Areca nut
Aristolochic acid
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
Aristolochic acid, plants containing
000069-53-4
051264-14-3
000523-50-2
000062-53-3
000090-04-0
000104-94-9
000191-26-4
000120-12-7
000118-92-3
000084-65-1
001309-64-4
001345-04-6
000052-46-0
024938-64-5
000140-57-8
000313-67-7
000313-67-7
Group
Volume
Year
2B
3
2B
3
3
3
3
3
3
27, Sup 7
8, Sup 7
8, Sup 7
16, Sup 7
1, Sup 7, 99,
100F
101
27, Sup 7
7, Sup 7
57
57
16, Sup 7
31, Sup 7
39, Sup 7
79
1987
1987
1987
1987
2012
in prep
1987
1987
1993
1993
1987
1987
1987
2001
3
2B
2A
3
3
3
2B
3
3
3
3
2B
2B
3
3
3
2B
1
1
50
76
Sup 7
11, Sup 7
40, Sup 7
27, Sup 7
73
27, Sup 7
92
92
16, Sup 7
101
47
47
9, Sup 7
68
5, Sup 7
85, 100E
82, 100A
1990
2000
1987
1987
1987
1987
1999
1987
2010
2010
1987
in prep
1989
1989
1987
1997
1987
2012
2012
82, 100A
2012

CAS No
Agent
Group
007440-38-2 Arsenic and inorganic arsenic compounds
064436-13-1 Arsenobetaine and other organic arsenic compounds that

are not metabolized in humans
Art glass, glass containers and pressed ware
(manufacture of)
001332-21-4 Asbestos (all forms, including actinolite, amosite,
013768-00-8 anthophyllite, chrysotile, crocidolite, tremolite)
(NB: Mineral substances (e.g. talc or vermiculite) that
012172-73-5
contain asbestos should also be regarded as
017068-78-9 carcinogenic to humans.)
012001-29-5
012001-28-4
014567-73-8
001912-24-9 Atrazine
012174-11-7 Attapulgite (see Palygorskite)
000492-80-8 Auramine
Auramine production
000151-56-4 Aziridine
(NB: Overall evaluation upgraded to Group 2B with
001072-52-2 2-(1-Aziridinyl)ethanol
000800-24-8 Aziridyl benzoquinone
000103-33-3 Azobenzene
000202-94-8 11H-Benz[bc]aceanthrylene
000202-33-5 Benz[j]aceanthrylene
supporting mechanistic and other relevant data)
000211-91-6 Benz[l]aceanthrylene
000225-11-6 Benz[a]acridine
Year
23, Sup 7,
100C
100C
2012
58
1993
14, Sup 7,
100C
2012
73
1999
1, Sup 7, 99,
100F
Sup 7, 99,
100F
13, Sup 7
50
2012
2A
2B
1
012192-57-3 Aurothioglucose
000320-67-2 Azacitidine
000115-02-6 Azaserine
000446-86-6 Azathioprine
Volume
3
2A
2B
1
2012
2012
1987
1990
1987
2012
2B
10, Sup 7
26, Sup 7,
100A
9, Sup 7, 71
3
3
3
3
2B
9, Sup 7
9, Sup 7
8, Sup 7
92
92
1987
1987
1987
2010
2010
3
3
92
32, Sup 7,
103
1999
2010
in prep

CAS No
Agent
Group
000225-51-4 Benz[c]acridine
000192-97-2
000105-11-3
000094-36-0
000140-11-4
001694-09-3
007440-41-7
32, Sup 7,
103
92
29, Sup 7.
100F
29, Sup 7,
99, 100F
99, 100F
in prep
3
3
3
2B
3
2B
2B
3
3
3
2B
3
3
2B
92
92
92
92
92
92
92
92
92
92
63
103
92
92
2010
2010
2010
2010
2010
2010
2010
2010
2010
2010
1995
in prep
2010
2010
2B
1
101
92, 100F
in prep
2012
3
3
3
3
2B
1
92
29, Sup 7, 71
36, Sup 7, 71
40, Sup 7, 71
16, Sup 7
58, 100C
2010
1999
1999
1999
1987
2012
85, 100E
85, 100E
2012
2012
2B
1
000092-87-5 Benzidine
000119-61-9
000050-32-8
Year
000056-55-3 Benz[a]anthracene
000071-43-2 Benzene
000214-17-5
000196-78-1
000203-33-8
000205-99-2
000203-12-3
000205-82-3
000207-08-9
000238-84-6
000243-17-4
000205-12-9
000271-89-6
000239-35-0
000191-24-2
000195-19-7
Volume
Benzidine, dyes metabolized to

Benzo[b]chrysene
Benzo[g]chrysene
Benzo[a]fluoranthene
Benzo[b]fluoranthene
Benzo[ghi]fluoranthene
Benzo[j]fluoranthene
Benzo[k]fluoranthene
Benzo[a]fluorene
Benzo[b]fluorene
Benzo[c]fluorene
Benzofuran
Benzo[b]naphtho[2,1-d]thiophene
Benzo[ghi]perylene
Benzo[c]phenanthrene
Benzophenone
Benzo[a]pyrene
Benzo[e]pyrene
para-Benzoquinone dioxime
Benzoyl peroxide
Benzyl acetate
Benzyl violet 4B
Beryllium and beryllium compounds
Beta particles (see Radionuclides)
Betel quid with tobacco
Betel quid without tobacco
1
1
2010
2012
2012
2012

CAS No
002168-68-5
003296-90-0
000111-44-4
000494-03-1
Agent
Group
Biomass fuel (primarily wood), indoor emissions from

household combustion of
Bis(1-aziridinyl)morpholinophosphine sulfide
2,2-Bis(bromomethyl)propane-1,3-diol
Bis(2-chloroethyl)ether
N,N-Bis(2-chloroethyl)-2-naphthylamine (see
Chlornaphazine)
Bischloroethyl nitrosourea (BCNU)
1,2-Bis(chloromethoxy)ethane
1,4-Bis(chloromethoxymethyl)benzene
Bis(chloromethyl)ether; chloromethyl methyl ether
(technical-grade)
000154-93-8
013483-18-6
056894-91-8
000542-88-1
000107-30-2
000108-60-1 Bis(2-chloro-1-methylethyl)ether
002386-90-5 Bis(2,3-epoxycyclopentyl)ether
000117-81-7 Bis(2-ethylhexyl) phthalate (see Di(2-ethylhexyl)
phthalate)
001675-54-3 Bisphenol A diglycidyl ether (Araldite)
Bisulfites
008052-42-4 Bitumens, extracts of steam-refined and air-refined;
steam-refined, cracking-residue and air-refined
bitumens
(see Bitumens, occupational exposures)
Bitumens, occupational exposure to hard bitumens and
their emissions during mastic asphalt work
064742-93-4 Bitumens, occupational exposure to oxidized bitumens
and their emissions during roofing
008052-42-4 Bitumens, occupational exposure to straight-run bitumens
064741-56-6 and their emissions during road paving
BK polyomavirus (BKV)
011056-06-7 Bleomycins
000129-17-9 Blue VRS
Boot and shoe manufacture and repair (see Leather dust,
Benzene)
Bracken fern
003844-45-9 Brilliant Blue FCF, disodium salt
005589-96-8 Bromochloroacetic acid
083463-62-1 Bromochloroacetonitrile
000075-27-4 Bromodichloromethane
000074-96-4 Bromoethane
Volume
Year
2A
95
2010
3
2B
3
9, Sup 7
77
9, Sup 7, 71
1987
2000
1999
2A
3
3
1
26, Sup 7
15; Sup 7, 71
15; Sup 7, 71
4, Sup 7,
100F
1987
1999
1999
2012
3
3
41, Sup 7, 71
47, 71
1999
1999
3
3
47, 71
54
35, Sup 7
1999
1992
1987
2B
103
in prep
2A
103
in prep
2B
103
in prep
2B
2B
104
26, Sup 7
in prep
1987
16, Sup 7
25, Sup 7
1987
1987
2B
3
2B
3
2B
3
40, Sup 7
16, Sup 7
101
52, 71
52, 71
52, 71
1987
1987
in prep
1999
1999
1999

CAS No
Agent
Group
000075-25-2 Bromoform
000055-98-1 Busulfan
3
1
000106-99-0
000055-98-1
000111-76-2
057018-52-7
000141-32-2
025013-16-5
000128-37-0
000085-68-7
003068-88-0
000096-48-0
007440-43-9
000331-39-5
000058-08-2
000056-25-7
000105-60-2
002425-06-1
000133-06-2
000063-25-2
000086-74-8
1,3-Butadiene
1,4-Butanediol dimethanesulfonate (see Busulfan)
2-Butoxyethanol
1-tert-Butoxypropan-2-ol
n-Butyl acrylate
Butylated hydroxyanisole (BHA)
Butylated hydroxytoluene (BHT)
Butyl benzyl phthalate
beta-Butyrolactone
gamma-Butyrolactone
Cadmium and cadmium compounds
Caffeic acid
Caffeine
Calcium carbide production
Cantharidin
Caprolactam
Captafol
Captan
Carbaryl
Carbazole
020073-24-9 3-Carbethoxypsoralen
001333-86-4 Carbon black
Carbon electrode manufacture
000056-23-5 Carbon tetrachloride
003567-69-9 Carmoisine
Carpentry and joinery
053973-98-1 Carrageenan, degraded (Poligeenan)
009000-07-1 Carrageenan, native
000120-80-9 Catechol
Chimney sweeping (see Soot)
000075-87-6 Chloral
000302-17-0 Chloral hydrate
Year
52, 71
4, Sup 7,
100A
97, 100F
1999
2012
3
3
3
2B
3
3
2B
3
1
2B
3
3
3
4
2A
88
88
39, Sup 7, 71
40, Sup 7
40, Sup 7
73
11, Sup 7, 71
11, Sup 7, 71
58, 100C
56
51
92
10, Sup 7
39, Sup 7, 71
53
2006
2006
1999
1987
1987
1999
1999
1999
2012
1993
1991
2010
1987
1999
1991
3
3
2B
30, Sup 7
12, Sup 7
32, Sup 7,
71, 103
40, Sup 7
65, 93
92
20, Sup 7, 71
8, Sup 7
25, Sup 7
31, Sup 7
31, Sup 7
15, Sup 7, 71
92
63, 106
84, 106
1987
1987
in prep
3
2B
2A
2B
3
2B
2B
3
2B
2A
2A
Volume
2012
1987
2010
2010
1999
1987
1987
1987
1987
1999
2010
in prep
in prep

CAS No
Agent
Group
000305-03-3 Chlorambucil
010599-90-3 Chloramine
000056-75-7 Chloramphenicol
000057-74-9 Chlordane
000143-50-0 Chlordecone (Kepone)
006164-98-3 Chlordimeform
000115-28-6 Chlorendic acid
Chlorinated drinking-water
Chlorinated paraffins of average carbon chain length C12
and average degree of chlorination approximately 60%
000098-87-3 alpha-Chlorinated toluenes (benzal chloride,
000098-07-7 benzotrichloride, benzyl chloride) and benzoyl chloride
(combined exposures)
000100-44-7
000098-88-4
000494-03-1 Chlornaphazine
000107-14-2
000106-47-8
000510-15-6
000124-48-1
077439-76-0
000075-45-6
000075-00-3
013010-47-4
013909-09-6
000593-70-4
000067-66-3
000107-30-2
000513-37-1
000563-47-3
000088-73-3
000121-73-3
000100-00-5
Chloroacetonitrile
para-Chloroaniline
Chlorobenzilate
Chlorodibromomethane
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
Chlorodifluoromethane
Chloroethane
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
(Methyl-CCNU) (see Semustine)
Chlorofluoromethane
Chloroform
Chloromethyl methyl ether (see Bis(chloromethyl)ether;
chloromethyl methyl ether)
1-Chloro-2-methylpropene
3-Chloro-2-methylpropene
Chloronitrobenzenes
Volume
Year
2012
3
2A
26, Sup 7,
100A
84
50
2B
2B
3
2B
3
2B
79
20, Sup 7
30, Sup 7
48
52
48
2001
1987
1987
1990
1991
1990
2A
29, Sup 7, 71
1999
2012
3
2B
3
3
2B
3
3
2A
4, Sup 7,
100A
52, 71
57
30, Sup 7
52, 71
84
41, Sup 7, 71
52, 71
26, Sup 7
1999
1993
1987
1999
2004
1999
1999
1987
3
2B
41, Sup 7, 71
73
1999
1999
2B
3
3
63
63
65
1995
1995
1996
2004
1990

CAS No
005131-60-2
000095-83-0
000126-99-8
000101-21-3
000054-05-7
001897-45-6
000095-69-2
000095-79-4
000075-88-7
054749-90-5
000057-88-5
007440-47-3
016065-83-1
018540-29-9
000218-01-9
000532-82-1
006373-74-6
000523-44-4
006459-94-5
000569-61-9
001937-37-7
002602-46-2
002429-74-5
016071-86-6
001936-15-8
002425-85-6
059865-13-3
051481-61-9
000087-29-6
015663-27-1
000518-75-2
006358-53-8
000637-07-0
Agent
Group
Chlorophenols (see Polychlorophenols)

Chlorophenoxy herbicides
4-Chloro-meta-phenylenediamine
4-Chloro-ortho-phenylenediamine
Chloroprene
Chloropropham
Chloroquine
Chlorothalonil
4-Chloro-ortho-toluidine
5-Chloro-ortho-toluidine
2-Chloro-1,1,1-trifluoroethane
Chlorozotocin
Cholesterol
Chromium, metallic
Chromium (III) compounds
Chromium (VI) compounds
Chrysene
Chrysoidine
CI Acid Orange 3
CI Acid Orange 20
CI Acid Red 114
CI Basic Red 9
CI Direct Black 38 (see Benzidine, dyes metabolized to)
CI Direct Blue 6 (see Benzidine, dyes metabolized to)
CI Direct Blue 15
CI Direct Brown 95 (see Benzidine, dyes metabolized to)
CI Orange G
CI Pigment Red 3
Ciclosporin (see Cyclosporine)
Cimetidine
Cinnamyl anthranilate
Cisplatin
Citrinin
Citrus Red No. 2
Clofibrate
Volume
Year
2B
3
2B
2B
3
3
2B
2A
3
3
2A
41, Sup 7
27, Sup 7
27, Sup 7
71
12, Sup 7
13, Sup 7
73
77, 99
77, 99
41, Sup 7, 71
50
1987
1987
1987
1999
1987
1987
1999
2010
2010
1999
1990
3
3
3
1
2B
3
3
3
2B
2B
31, Sup 7
49
49
49, 100C
92
8, Sup 7
57
8, Sup 7
57
57, 99
1987
1990
1990
2012
2010
1987
1993
1987
1993
2010
2B
57
1993
3
3
8, Sup 7
57
1987
1993
3
3
2A
50
77
26, Sup 7
1990
2000
1987
3
2B
3
40, Sup 7
8, Sup 7
66
1987
1987
1996

CAS No
Agent
Group
000050-41-9 Clomiphene citrate

Clonorchis sinensis (infection with)
Coal, indoor emissions from household combustion of
Coal dust
Coal gasification
008007-45-2 Coal tars (see Coal-tar distillation)
008007-45-2 Coal-tar distillation
065996-93-2 Coal-tar pitch
007440-48-4 Cobalt and cobalt compounds
(NB: Evaluated as a group)
007440-48-4 Cobalt metal with tungsten carbide
012070-12-1
007440-48-4 Cobalt metal without tungsten carbide
010026-24-1 Cobalt sulfate and other soluble cobalt(II) salts
068603-42-9 Coconut oil diethanolamine condensate
Coffee (urinary bladder)
(NB: There is some evidence of an inverse relationship
between coffee drinking and cancer of the large bowel;
coffee drinking could not be classified as to its
carcinogenicity to other organs)
Coke production
Continuous glass filament (see Glass filament)
010380-28-6 Copper 8-hydroxyquinoline
000191-07-1 Coronene
000091-64-5 Coumarin
008001-58-9 Creosotes
000102-50-1 meta-Cresidine
000120-71-8 para-Cresidine
004170-30-3 Crotonaldehyde
008002-05-9 Crude oil
000098-82-8 Cumene
014901-08-7 Cycasin
000139-05-9 Cyclamates (sodium cyclamate)
012663-46-6 Cyclochlorotine
000108-94-1 Cyclohexanone
000202-98-2 4H-Cyclopenta[def]chrysene
027208-37-3 Cyclopenta[cd]pyrene
3
1
1
3
1
Volume
Year
1987
2012
2012
1997
2012
1987
2012
2012
2B
21, Sup 7
61, 100B
95, 100E
68
92, 100F
35, Sup 7
92, 100F
35, Sup 7,
100F
52
2A
86
2006
2B
2B
2B
2B
86
86
101
51
2006
2006
in prep
1991
1
1
1991
92, 100F
2012
3
3
3
2A
3
2B
3
3
2B
2B
3
3
3
3
2A
15, Sup 7
32, Sup 7
77
92
27, Sup 7
27, Sup 7
63
45
101
10, Sup 7
73
10, Sup 7
47, 71
92
92
1987
1987
2000
2010
1987
1987
1995
1989
in prep
1987
1999
1987
1999
2010
2010

CAS No
Agent
Group
007099-43-6
000050-18-0
006055-19-2
059865-13-3
079217-60-0
004342-03-4
005160-02-1
000117-10-2
000080-08-0
020830-81-3
000050-29-3
001163-19-5
052918-63-5
000083-63-6
000613-35-4
002303-16-4
000615-05-4
000101-80-4
000099-56-9
005307-14-2
000095-80-7
000095-70-5
000439-14-5
000334-88-3
000226-36-8
5,6-Cyclopenteno-1,2-benzanthracene
Cyclophosphamide
3
1
92
26, Sup 7,
100A
2010
2012
Cyclosporine
50, 100A
2012
2B
3
2B
3
2B
2B
3
3
3
2B
3
2B
2B
3
3
2B
3
3
3
2B
26, Sup 7
57
50
24, Sup 7
10, Sup 7
53
48, 71
53
8, Sup 7
16, Sup 7
30, Sup 7
79
29, Sup 7
16, Sup 7
57
16, Sup 7
16, Sup 7
66
7, Sup 7
32, Sup 7,
103
32, Sup 7,
103
1987
1993
1990
1987
1987
1991
1999
1991
1987
1987
1987
2001
1987
1987
1993
1987
1987
1996
1987
in prep
2B
103
in prep
3
2A
92
92
2010
2010
3
2B
92
32, Sup 7,
103
69
Dacarbazine
D & C Red No. 9
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone)
Dapsone
Daunomycin
DDT (4,4'-Dichlorodiphenyltrichloroethane)
Decabromodiphenyl oxide
Deltamethrin
Diacetylaminoazotoluene
N,N'-Diacetylbenzidine
Diallate
2,4-Diaminoanisole
4,4'-Diaminodiphenyl ether
1,2-Diamino-4-nitrobenzene
1,4-Diamino-2-nitrobenzene
2,4-Diaminotoluene
2,5-Diaminotoluene
Diazepam
Diazomethane
Dibenz[a,h]acridine
000224-42-0 Dibenz[a,j]acridine
000224-53-3 Dibenz[c,h[acridine
000215-58-7 Dibenz[a,c]anthracene
000053-70-3 Dibenz[a,h]anthracene
000224-41-9 Dibenz[a,j]anthracene
000194-59-2 7H-Dibenzo[c,g]carbazole
000262-12-4 Dibenzo-para-dioxin
2A
10
Volume
Year
in prep
2010
in prep
1997

CAS No
Agent
005385-75-1
000207-83-0
000192-47-2
000192-65-4
000189-64-0
000189-55-9
000191-30-0
Dibenzo[a,e]fluoranthene
13H-Dibenzo[a,g]fluorene
Dibenzo[h,rst]pentaphene
Dibenzo[a,e]pyrene
Dibenzo[a,h]pyrene
Dibenzo[a,i]pyrene
Dibenzo[a,l]pyrene
Dibenzo[e,l]pyrene
Dibenzothiophene
Dibromoacetic acid
Dibromoacetonitrile
1,2-Dibromo-3-chloropropane
2,3-Dibromopropan-1-ol
Dichloroacetic acid
Dichloroacetonitrile
Dichloroacetylene
meta-Dichlorobenzene
ortho-Dichlorobenzene
para-Dichlorobenzene
3,3'-Dichlorobenzidine
trans-1,4-Dichlorobutene
3,3'-Dichloro-4,4'-diaminodiphenyl ether
1,2-Dichloroethane
Dichloromethane (Methylene chloride)
2,6-Dichloro-para-phenylenediamine
1,2-Dichloropropane
1,3-Dichloro-2-propanol
1,3-Dichloropropene (technical-grade)
Dichlorvos
Dicofol
Didanosine
Dieldrin
1,2:3,4-Diepoxybutane (see Monographs on 1,3Butadiene)
Diesel engine exhaust (see Engine exhaust, diesel)
Diesel fuels, distillate (light)
000192-51-8
000132-65-0
000631-64-1
003252-43-5
000096-12-8
000096-13-9
000079-43-6
003018-12-0
007572-29-4
000541-73-1
000095-50-1
000106-46-7
000091-94-1
000110-57-6
028434-86-8
000107-06-2
000075-09-2
000609-20-1
000078-87-5
000096-23-1
000542-75-6
000062-73-7
000115-32-2
069655-05-6
000060-57-1
001464-53-5
Group
11
Volume
3
3
3
3
2B
2B
2A
92
92
92
92
92
92
92
3
3
2B
2B
2B
2B
2B
3
3
3
3
2B
2B
3
2B
2B
2B
3
3
2B
2B
2B
3
3
3
92
103
101
52, 71, 101
20, Sup 7, 71
77
84, 106
52, 71
39, Sup 7, 71
73
73
73
29, Sup 7
15, Sup 7, 71
16, Sup 7
20, Sup 7, 71
71
39, Sup 7
41, Sup 7, 71
101
41, Sup 7, 71
53
30, Sup 7
76
5, Sup 7
11, Sup 7
45
Year
2010
2010
2010
2010
2010
2010
2010
2010
in prep
in prep
in prep
1999
2000
in prep
1999
1999
1999
1999
1999
1987
1999
1987
1999
1999
1987
1999
in prep
1999
1991
1987
2000
1987
1987
1989

CAS No
Agent
Group
000111-42-2
000103-23-1
000117-81-7
001615-80-1
000056-53-1
Diesel fuel, marine

Diethanolamine
Di(2-ethylhexyl) adipate
Di(2-ethylhexyl)phthalate
1,2-Diethylhydrazine
Diethylstilbestrol
000064-67-5 Diethyl sulfate

000105-55-5 N,N'-Diethylthiourea
000101-90-6 Diglycidyl resorcinol ether
000641-48-5 Dihydroaceanthrylene
000094-58-6 Dihydrosafrole
000794-93-4 Dihydroxymethylfuratrizine (see also Panfuran S)
002973-10-6 Diisopropyl sulfate
000828-00-2 Dimethoxane
000119-90-4 3,3'-Dimethoxybenzidine (ortho-Dianisidine)
000091-93-0 3,3'-Dimethoxybenzidine-4,4'-diisocyanate
000060-11-7 para-Dimethylaminoazobenzene
000140-56-7 para-Dimethylaminoazobenzenediazo sodium sulfonate
025962-77-0 trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2furyl)-vinyl]-1,3,4-oxadiazole
022975-76-4 4,4'-Dimethylangelicin plus ultraviolet A radiation
004063-41-6 4,5'-Dimethylangelicin plus ultraviolet A radiation
000087-62-7 2,6-Dimethylaniline (2,6-Xylidine)
000121-69-7 N,N-Dimethylaniline
000075-60-5 Dimethylarsenic acid
000119-93-7 3,3'-Dimethylbenzidine (ortho-Tolidine)
000079-44-7 Dimethylcarbamoyl chloride
000068-12-2 Dimethylformamide
000057-14-7 1,1-Dimethylhydrazine
000540-73-8 1,2-Dimethylhydrazine
000868-85-9 Dimethyl hydrogen phosphite
12
Volume
Year
2B
45
2B
3
2B
2B
1
in prep
2000
in prep
1999
2012
2A
77, 101
77
77, 101
4, Sup 7, 71
21, Sup 7,
100A
54, 71
3
2B
3
2B
3
2B
3
2B
3
2B
3
2B
79
36, Sup 7, 71
92
10, Sup 7
24, Sup 7
54, 71
15, Sup 7
4, Sup 7
39, Sup 7
8, Sup 7
8, Sup 7
7, Sup 7
2001
1999
2010
1987
1987
1999
1987
1987
1987
1987
1987
1987
3
3
2B
3
2B
2B
2A
Sup 7
Sup 7
57
57
100C
1, Sup 7
12, Sup 7, 71
1987
1987
1993
1993
2012
1987
1999
3
2B
2A
47, 71
4, Sup 7, 71
4, Sup 7, 71
1999
1999
1999
48, 71
1999
1989
1999

CAS No
Agent
Group
022349-59-3 1,4-Dimethylphenanthrene
000077-78-1 Dimethyl sulfate
105735-71-5 3,7-Dinitrofluoranthene
022506-53-2 3,9-Dinitrofluoranthene
075321-20-9 1,3-Dinitropyrene
000101-25-7 Dinitrosopentamethylenetetramine
000121-14-2 2,4-Dinitrotoluene
000123-91-1 1,4-Dioxane
000492-17-1 2,4'-Diphenyldiamine
002475-45-8 Disperse Blue 1
002832-40-8 Disperse Yellow 3
000097-77-8 Disulfiram
001143-38-0 Dithranol
040762-15-0 Doxefazepam
000562-10-7 Doxylamine succinate
082413-20-5 Droloxifene
Dry cleaning (occupational exposures in)
000150-69-6 Dulcin
Dyes metabolized to benzidine (see Benzidine, dyes
metabolized to)
Electric fields, extremely low-frequency
Electric fields, static
000072-20-8 Endrin
Engine exhaust, diesel
Engine exhaust, gasoline
015086-94-9 Eosin
000106-89-8 Epichlorohydrin
000106-88-7 1,2-Epoxybutane
000141-37-7 3,4-Epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6methylcyclo-hexanecarboxylate
13
Volume
Year
3
2A
92
4, Sup 7, 71
2010
1999
2B
2B
2B
2B
2B
3
2B
2B
3
2B
3
2B
3
3
3
3
3
3
2B
3
65, 105
65, 105
46, 105
46, 105
46, 105
11, Sup 7
65
65
65
11, Sup 7, 71
16, Sup 7
48
48
12, Sup 7
13; Sup 7
66
79
66
63
12, Sup 7
in prep
in prep
in prep
in prep
in prep
1987
1996
1996
1996
1999
1987
1990
1990
1987
1987
1996
2001
1996
1995
1987
3
3
3
1
2B
3
2A
80
80
5, Sup 7
46, 105
46, 105
15, Sup 7
11, Sup 7, 71
2002
2002
1987
in prep
in prep
1987
1999
2B
47, 71
1999
11, Sup 7, 71
1999

CAS No
Agent
Group
002443-39-2 cis-9,10-Epoxystearic acid

Epstein-Barr virus
066733-21-9 Erionite
3
1
1
029975-16-4 Estazolam
Estrogen therapy, postmenopausal
Estrogen-progestogen menopausal therapy (combined)
Estrogen-progestogen oral contraceptives (combined)
(NB: There is also convincing evidence in humans that
these agents confer a protective effect against cancer in
the endometrium and ovary)
000064-17-5 Ethanol in alcoholic beverages
000536-33-4 Ethionamide
000140-88-5 Ethyl acrylate
000100-41-4 Ethylbenzene
000051-79-6 Ethyl carbamate (Urethane)
000074-85-1 Ethylene
000106-93-4 Ethylene dibromide
000075-21-8 Ethylene oxide
000420-12-2 Ethylene sulfide
000096-45-7 Ethylenethiourea
000103-11-7 2-Ethylhexyl acrylate
000062-50-0 Ethyl methanesulfonate
000759-73-9 N-Ethyl-N-nitrosourea
005456-28-0 Ethyl selenac
020941-65-5 Ethyl tellurac
033419-42-0 Etoposide
033419-42-0 Etoposide in combination with cisplatin and bleomycin
015663-27-1
011056-06-7
000097-53-0 Eugenol
14
Volume
Year
1999
2012
2012
3
1
1
1
11, Sup 7, 71
70, 100B
42, Sup 7,
100C
66
72, 100A
72, 91, 100A
72, 91, 100A
1
3
2B
2B
2A
3
2A
96, 100E
13, Sup 7
39, Sup 7, 71
77
7, Sup 7, 96
60
15, Sup 7, 71
2012
1987
1999
2000
2010
1994
1999
97, 100F
2012
3
3
11, Sup 7
79
1987
2001
3
2B
2A
60
7, Sup 7
17, Sup 7
1994
1987
1987
3
3
1
12, Sup 7
12, Sup 7
76, 100A
1987
1987
2012
76, 100A
2012
36, Sup 7
1987
1996
2012
2012
2012

CAS No
Agent
000314-13-6
002353-45-9
051630-58-1
014484-64-1
001309-37-1
Evans blue
Fast Green FCF
Fenvalerate
Ferbam
Ferric oxide
Firefighter (occupational exposure as a)
Fission products, including strontium-90
Flat-glass and specialty glass (manufacture of)
Fluometuron
Fluoranthene
Fluorene
Fluorescent lighting
Fluorides (inorganic, used in drinking-water)
5-Fluorouracil
Foreign bodies (see Surgical implants and other foreign
bodies)
Formaldehyde
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
Frying, emissions from high-temperature
Fuel oils, distillate (light)
Fuel oils, residual (heavy)
Fumonisin B1
Furan
Furazolidone
Furfural
Furniture and cabinet making (see Wood dust)
Furosemide (Frusemide)
Fusarium graminearum, F. culmorum, and F.
crookwellense, toxins derived from (zearalenone,
deoxynivalenol, nivalenol, and fusarenone X)
Fusarium moniliforme, toxins derived from (fumonisin B1,
fumonisin B2, and fusarin C)
Fusarium sporotrichioides, toxins derived from (T-2 toxin)
Gallium arsenide (see Arsenic and inorganic arsenic
compounds)
Gamma-Radiation (see X- and Gamma-Radiation)
Gasoline
Gasoline engine exhaust (see Engine exhaust, gasoline)
002164-17-2
000206-44-0
000086-73-7
016984-48-8
000051-21-8
000050-00-0
003570-75-0
116355-83-0
000110-00-9
000067-45-8
000098-01-1
000054-31-9
116355-83-0
001303-00-0
Group
15
Volume
Year
3
3
3
3
3
2B
1
3
3
3
3
3
3
3
8, Sup 7
16, Sup 7
53
12, Sup 7
1, Sup 7
98
100D
58
30, Sup 7
92
92
55
27, Sup 7
26, Sup 7
1987
1987
1991
1987
1987
2010
2012
1993
1987
2010
2010
1992
1987
1987
1
2B
2A
3
2B
2B
2B
3
3
88, 100F
7, Sup 7
95
45
45
82
63
31, Sup 7
63
25, Sup 7
50
56
2012
1987
2010
1989
1989
2002
1995
1987
1995
1987
1990
1993
56
1993
56
86, 100C
1993
2012
45
1989
3
3
2B
3
2B

CAS No
Agent
Group
025812-30-0 Gemfibrozil
Glass filament, continuous
067730-11-4 Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'd]imidazole)
067730-10-3 Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
000765-34-4 Glycidaldehyde
000556-52-5 Glycidol
005431-33-4 Glycidyl oleate
007460-84-6 Glycidyl stearate
000126-07-8 Griseofulvin
004680-78-8 Guinea Green B
016568-02-8 Gyromitrin
001317-60-8 Haematite
Haematite mining (underground)
002784-94-3
033229-34-4
002871-01-4
059820-43-8
000076-44-8
000118-74-1
000087-68-3
000067-72-1
000070-30-4
000142-83-6
000680-31-9
Hair colouring products (personal use of)

Hairdresser or barber (occupational exposure as a)
HC Blue No. 1
HC Blue No. 2
HC Red No. 3
HC Yellow No. 4
Helicobacter pylori (infection with)
Hepatitis B virus (chronic infection with)
Hepatitis C virus (chronic infection with)
Hepatitis D virus
Heptachlor
Hexachlorobenzene
Hexachlorobutadiene
Hexachlorocyclohexanes
Hexachloroethane
Hexachlorophene
2,4-Hexadienal
Hexamethylphosphoramide
High-temperature frying (see Frying)
Hot mate (see Mate, hot)
Household combustion of biomass fuel (see Biomass
fuel, indoor emissions from household combustion of)
16
Volume
Year
3
3
2B
66
43, 81
40, Sup 7
1996
2002
1987
2B
2B
2A
40, Sup 7
11, Sup 7, 71
77
1987
1999
2000
3
3
2B
3
3
3
1
11, Sup 7
11, Sup 7
79
16, Sup 7
31, Sup 7
1, Sup 7
1, Sup 7,
100D
57, 99
57, 99
57
57
57
57
61, 100B
59, 100B
59, 100B
59
79
79
73
20, Sup 7
73
20, Sup 7
101
15, Sup 7, 71
1987
1987
2001
1987
1987
1987
2012
3
2A
2B
3
3
3
1
1
1
3
2B
2B
3
2B
2B
3
2B
2B
2010
2010
1993
1993
1993
1993
2012
2012
2012
1994
2001
2001
1999
1987
1999
1987
in prep
1999

CAS No
023255-93-8
000086-54-4
000302-01-2
007647-01-0
000058-93-5
007722-84-1
000123-31-9
000129-43-1
001689-82-3
000148-24-3
026782-43-4
000127-07-1
000193-39-5
022398-80-7
Agent
Group
Household combustion of coal (see Coal, indoor

emissions from household combustion)
Human herpesvirus type 4 (see Epstein-Barr virus)
Human herpesvirus type 8 (see Kaposi sarcoma
herpesvirus)
Human immunodeficiency virus type 1 (infection with)
Human immunodeficiency virus type 2 (infection with)
Human papillomavirus genus beta (except types 5 and 8)
and genus gamma
Human papillomavirus types 5 and 8 (in patients with
epidermodysplasia verruciformis)
Human papillomavirus types 6 and 11
Human papillomavirus types 16, 18, 31, 33, 35, 39, 45,
51, 52, 56, 58, 59
(NB: The HPV types that have been classified as
carcinogenic to humans can differ by an order of
magnitude in risk for cervical cancer)
Human papillomavirus types 26, 53, 66, 67, 70, 73, 82
Human papillomavirus types 30, 34, 69, 85, 97
(NB: Classified by phylogenetic analogy to the HPV
genus alpha types classified in Group 1)
Human papillomavirus type 68
Human T-cell lymphotropic virus type I
Human T-cell lymphotropic virus type II
Hycanthone mesylate
Hydralazine
Hydrazine
Hydrochloric acid
Hydrochlorothiazide
Hydrogen peroxide
Hydroquinone
1-Hydroxyanthraquinone
4-Hydroxyazobenzene
8-Hydroxyquinoline
Hydroxysenkirkine
Hydroxyurea
Hypochlorite salts
Indeno[1,2,3-cd]pyrene
Indium phosphide
(NB: Overall evaluation upgraded to Group 2A)
Insulation glass wool
17
Volume
Year
1
2B
3
67, 100B
67
90, 100B
2012
1996
2012
2B
100B
2012
90, 100B
64, 90, 100B
2012
2012
2B
2B
100B
100B
2012
2012
2A
1
3
3
3
2B
3
3
3
3
2B
3
3
3
3
3
2B
2A
100B
67, 100B
67
13, Sup 7
24, Sup 7
4, Sup 7, 71
54
50
36, Sup 7, 71
15, Sup 7, 71
82
8, Sup 7
13, Sup 7
10, Sup 7
76
52
92
86
2012
2012
1996
1987
1987
1999
1992
1990
1999
1999
2002
1987
1987
1987
2000
1991
2010
2006
43, 81
2002
3
1

CAS No
Agent
Group
Involuntary smoking (see Tobacco smoke, second-hand)

010043-66-0 Iodine-131 (see Radioiodines)
Ionizing radiation (all types)
076180-96-6 IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)
Iron and steel founding (occupational exposure during)
009004-66-4
009004-51-7
001338-16-5
015503-86-3
000054-85-3
003778-73-2
000078-79-5
000067-63-0
000120-58-1
006870-67-3
000520-18-3
000501-30-4
000303-34-4
000105-74-8
007439-92-1
005141-20-8
Iron-dextran complex
Iron-dextrin complex
Iron sorbitol-citric acid complex
Isatidine
Isonicotinic acid hydrazide (Isoniazid)
Isophosphamide
Isoprene
Isopropyl alcohol
Isopropyl alcohol manufacture using strong acids
Isopropyl oils
Isosafrole
Jacobine
JC polyomavirus (JCV)
Jet fuel
Kaempferol
Kaposi sarcoma herpesvirus
Kojic acid
Lasiocarpine
Lauroyl peroxide
Lead
Lead compounds, inorganic
Lead compounds, organic
(NB: Organic lead compounds are metabolized at least
in part, to ionic lead both in humans and animals. To the
extent that ionic lead, generated from organic lead, is
present in the body, it will be expected to exert the
toxicities associated with inorganic lead.)
Leather dust
Leather goods manufacture
Leather tanning and processing
Light Green SF
18
1
2A
1
2B
3
3
3
3
3
2B
3
1
3
3
3
2B
3
3
1
3
2B
3
2B
2A
3
1
3
3
3
Volume
Year
100D
56
2012
1993
34, Sup 7,
100F
2, Sup 7
2, Sup 7
2, Sup 7
10, Sup 7
4, Sup 7
26, Sup 7
60, 71
15, Sup 7, 71
Sup 7, 100F
15, Sup 7, 71
10, Sup 7
10, Sup 7
104
45
31, Sup 7
70, 100B
79
10, Sup 7
36, Sup 7, 71
23, Sup 7
87
23, Sup 7, 87
2012
100C
25, Sup 7
25, Sup 7
16, Sup 7
1987
1987
1987
1987
1987
1987
1999
1999
2012
1999
1987
1987
in prep
1989
1987
2012
2001
1987
1999
1987
2006
2006
2012
1987
1987
1987

CAS No
Agent
Group
005989-27-5 d-Limonene
Lumber and sawmill industries (including logging)
021884-44-6 Luteoskyrin
Madder root (Rubia tinctorum)
000632-99-5 Magenta
Magenta production
Magnetic fields, extremely low-frequency
Magnetic fields, static
Malaria (caused by infection with Plasmodium falciparum
in holoendemic areas)
000121-75-5 Malathion
000123-33-1 Maleic hydrazide
000542-78-9 Malonaldehyde
012427-38-2 Maneb
000551-74-6 Mannomustine dihydrochloride
Mate
Mate, hot
068006-83-7 MeA-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
013045-94-8 Medphalan
000071-58-9 Medroxyprogesterone acetate
077094-11-2 MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
077500-04-0 MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
000108-78-1 Melamine
000148-82-3 Melphalan
000050-44-2 6-Mercaptopurine
007439-97-6 Mercury and inorganic mercury compounds
Merkel cell polyomavirus (MCV)
000531-76-0 Merphalan
Metabisulfites
000060-56-0 Methimazole
000059-05-2 Methotrexate
000072-43-5 Methoxychlor
000298-81-7 Methoxsalen (8-methoxypsoralen) plus ultraviolet A
radiation
19
Volume
73
Year
1999
3
3
3
2B
1
2B
3
2A
25, Sup 7
10, Sup 7
82
57, 99, 100F
57, 99, 100F
80
80
104
1987
1987
2002
2012
2012
2002
2002
in prep
3
3
3
3
3
3
2A
2B
3
2B
2B
2B
3
30, Sup 7
4, Sup 7
36, Sup 7, 71
12, Sup 7
9, Sup 7
51
51
40, Sup 7
9, Sup 7
21, Sup 7
56
56
73
1987
1987
1999
1987
1987
1991
1991
1987
1987
1987
1993
1993
1999
9, Sup 7,
100A
26, Sup 7
58
104
9, Sup 7
54
79
26, Sup 7
20, Sup 7
24, Sup 7,
100A
2012
1
3
3
2A
2B
3
3
3
3
1
1987
1993
in prep
1987
1992
2001
1987
1987
2012

CAS No
Agent
Group
000484-20-8 5-Methoxypsoralen
000096-33-3 Methyl acrylate
073459-03-7 5-Methylangelicin plus ultraviolet A radiation
000124-58-3 Methylarsonic acid
000075-55-8 2-Methylaziridine (Propyleneimine)
000592-62-1 Methylazoxymethanol acetate
000074-83-9 Methyl bromide
001634-04-4 Methyl tert-butyl ether
000598-55-0 Methyl carbamate
000074-87-3 Methyl chloride
003351-28-8 1-Methylchrysene
000099-80-9 N-Methyl-N,4-dinitrosoaniline
000101-14-4 4,4'-Methylenebis(2-chloroaniline) (MOCA)
000838-88-0 4,4'-Methylene bis(2-methylaniline)
000101-77-9 4,4'-Methylenedianiline
000101-68-8 4,4'-Methylenediphenyl diisocyanate
000093-15-2 Methyleugenol
033543-31-6 2-Methylfluoranthene
001706-01-0 3-Methylfluoranthene
000078-98-8 Methylglyoxal
000693-98-1 2-Methylimidazole
000822-36-6 4-Methylimidazole
000074-88-4 Methyl iodide
000108-10-1 Methyl isobutyl ketone
Methylmercury compounds
000080-62-6 Methyl methacrylate
000066-27-3 Methyl methanesulfonate
000129-15-7 2-Methyl-1-nitroanthraquinone (uncertain purity)
20
Volume
Year
2A
40, Sup 7
1987
3
3
2B
2B
2B
3
3
3
3
3
3
3
3
2B
3
3
1
39, Sup 7, 71
Sup 7
100C
9, Sup 7, 71
10, Sup 7
41, Sup 7, 71
73
12, Sup 7
41, Sup 7, 71
92
92
92
92
92
92
1, Sup 7
57, 99, 100F
1999
1987
2012
1999
1987
1999
1999
1987
1999
2010
2010
2010
2010
2010
2010
1987
2012
2B
2B
3
2B
3
3
3
2B
2B
3
2B
2B
4, Sup 7
39, Sup 7
19, Sup 7, 71
101
92
92
51
101
101
41, Sup 7, 71
101
58
1987
1987
1999
in prep
2010
2010
1991
in prep
in prep
1999
in prep
1993
3
2A
60
7, Sup 7, 71
1994
1999
2B
27, Sup 7
1987

CAS No
Agent
Group
Volume
2A
4, Sup 7
1987
2A
17, Sup 7
1987
2B
3
3
3
3
3
3
2B
4, Sup 7
60
30, Sup 7
92
40, Sup 7
8, Sup 7
12, Sup 7
101
1987
1994
1987
2010
1987
1987
1987
in prep
000056-04-2 Methylthiouracil
000443-48-1 Metronidazole
000101-61-1 Michlers base [4,4 -methylenebis(N,N-dimethyl)benzenamine]
000090-94-8 Michlers ketone [4,4 -Bis(dimethylamino)benzophenone]
101043-37-2 Microcystin-LR
Microcystis extracts
Mineral oils, highly-refined
Mineral oils, untreated or mildly treated
2B
2B
2B
79
13, Sup 7
27, Sup 7, 99
2001
1987
2010
2B
99
2010
2B
3
3
1
2010
2010
1987
2012
002385-85-5 Mirex
000050-07-7 Mitomycin C
065271-80-9 Mitoxantrone
Modacrylic fibres
000096-24-2 3-Monochloro-1,2-propanediol
000315-22-0 Monocrotaline
000150-68-5 Monuron
MOPP and other combined chemotherapy including
alkylating agents
000110-91-8 Morpholine
003795-88-8 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2oxazolidinone
000083-66-9 Musk ambrette
000081-15-2 Musk xylene
000505-60-2 Mustard gas (see Sulfur mustard)
2B
2B
2B
3
2B
2B
3
1
94
94
33, Sup 7
33, Sup 7,
100F
20, Sup 7
10, Sup 7
76
19, Sup 7
101
10, Sup 7
53
Sup 7, 100A
3
2B
47, 71
7, Sup 7
1999
1987
65
65
1996
1996
000070-25-7 N-Methyl-N-nitro-N-nitrosoguanidine (MNNG)

000684-93-5 N-Methyl-N-nitrosourea
000615-53-2 N-Methyl-N-nitrosourethane
090456-67-0 N-Methylolacrylamide
000298-00-0 Methyl parathion
000832-69-9 1-Methylphenanthrene
085878-63-3 7-Methylpyrido[3,4-c]psoralen
000493-52-7 Methyl red
000144-34-3 Methyl selenac
000098-83-9 -Methylstyrene
21
3
3
Year
1987
1987
2000
1987
in prep
1987
1991
2012

CAS No
Agent
000055-98-1
003771-19-5
000091-20-3
002243-62-1
003173-72-6
111189-32-3
000203-20-3
000193-09-9
000134-32-7
000091-59-8
Myleran (see Busulfan)

Nafenopin
Naphthalene
1,5-Naphthalenediamine
1,5-Naphthalene diisocyanate
Naphtho[1,2-b]fluoranthene
Naphtho[2,1-a]fluoranthene
Naphtho[2,3-e]pyrene
1-Naphthylamine
2-Naphthylamine
Group
2B
2B
3
3
3
3
3
3
1
000086-88-4 1-Naphthylthiourea (ANTU)

000139-94-6 Nithiazide
Neutron radiation
(NB: Overall evaluation upgraded to Group 1 with
007440-02-0 Nickel, metallic and alloys
Nickel compounds
Nickel refining (see Nickel compounds)
000061-57-4 Niridazole
Nitrate or nitrite (ingested) under conditions that result in
endogenous nitrosation
000139-13-9 Nitrilotriacetic acid and its salts
000602-87-9 5-Nitroacenaphthene
000099-59-2 5-Nitro-ortho-anisidine
000091-23-6 2-Nitroanisole
000602-60-8 9-Nitroanthracene
017117-34-9 3-Nitrobenzanthrone
000098-95-3 Nitrobenzene
020268-51-3 7-Nitrobenz[a]anthracene
063041-90-7 6-Nitrobenzo[a]pyrene
000092-93-3 4-Nitrobiphenyl
007496-02-8 6-Nitrochrysene
001836-75-5 Nitrofen (technical-grade)
000892-21-7 3-Nitrofluoranthene
000607-57-8 2-Nitrofluorene
000059-87-0 Nitrofural (Nitrofurazone)
000067-20-9 Nitrofurantoin
22
Volume
Year
24, Sup 7
82
27, Sup 7
19, Sup 7, 71
92
92
92
4, Sup 7
4, Sup 7, 99,
100F
30, Sup 7
31, Sup 7
75, 100D
1987
2002
1987
1999
2010
2010
2010
1987
2012
2B
2A
49
49, 100C
11
13, Sup 7
94
1990
2012
1976
1987
2010
2B
73
1999
2B
3
2B
3
2B
2B
3
3
3
2A
2B
3
2B
3
3
16, Sup 7
27, Sup 7
65
33, Sup 7
105
65
46
46
4, Sup 7
46, 105
30, Sup 7
33, Sup 7
46, 105
50
50
3
3
1
2B
1
1987
1987
2012
1987
1987
1996
1987
in prep
1996
1989
1989
1987
in prep
1987
1987
in prep
1990
1990

CAS No
Agent
000555-84-0
000531-82-8
000051-75-2
000126-85-2
000075-52-5
000086-57-7
000581-89-5
020589-63-3
000079-46-9
005522-43-0
000789-07-1
057835-92-4
037620-20-5
071267-22-6
000924-16-3
001116-54-7
000055-18-5
1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
Nitrogen mustard
Nitrogen mustard N-oxide
Nitromethane
1-Nitronaphthalene
2-Nitronaphthalene
3-Nitroperylene
2-Nitropropane
1-Nitropyrene
2-Nitropyrene
4-Nitropyrene
N'-Nitrosoanabasine (NAB)
N'-Nitrosoanatabine (NAT)
N-Nitrosodi-n-butylamine
N-Nitrosodiethanolamine
N-Nitrosodiethylamine
N-Nitrosodimethylamine
N-Nitrosodiphenylamine
para-Nitrosodiphenylamine
N-Nitrosodi-n-propylamine
N-Nitrosofolic acid
N-Nitrosoguvacine
N-Nitrosoguvacoline
N-Nitrosohydroxyproline
3-(N-Nitrosomethylamino)propionaldehyde
3-(N-Nitrosomethylamino)propionitrile
N-Nitrosomethylethylamine
N-Nitrosomethylvinylamine
N-Nitrosomorpholine
N'-Nitrosonornicotine (NNN) and 4-(NNitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)
N-Nitrosopiperidine
N-Nitrosoproline
000062-75-9
000086-30-6
000156-10-5
000621-64-7
029291-35-8
055557-01-2
055557-02-3
030310-80-6
085502-23-4
060153-49-3
010595-95-6
004549-40-0
000059-89-2
016543-55-8
064091-91-4
000100-75-4
007519-36-0
Group
23
Volume
Year
2B
2B
2A
2B
2B
3
3
3
2B
2A
3
2B
3
3
2B
2B
2A
7, Sup 7
7, Sup 7
9, Sup 7
9, Sup 7
77
46
46
46
29, Sup 7, 71
46, 105
46
46, 105
37, Sup 7, 89
37, Sup 7, 89
17, Sup 7
17, Sup 7, 77
17, Sup 7
1987
1987
1987
1987
2000
1989
1989
1989
1999
in prep
1989
in prep
2007
2007
1987
2000
1987
2A
17, Sup 7
1987
3
3
2B
3
3
3
3
3
2B
2B
2B
2B
1
27, Sup 7
27, Sup 7
17, Sup 7
17, Sup 7
85
85
17, Sup 7
85
85
17, Sup 7
17, Sup 7
17, Sup 7
89, 100E
1987
1987
1987
1987
2004
2004
1987
2004
2004
1987
1987
1987
2012
2B
3
17, Sup 7
17, Sup 7
1987
1987

CAS No
Agent
Group
000930-55-2 N-Nitrosopyrrolidine
013256-22-9 N-Nitrososarcosine
000088-72-2 2-Nitrotoluene
000099-08-1 Nitrotoluenes
000099-99-0
000099-55-8 5-Nitro-ortho-toluidine
000804-36-4 Nitrovin
118399-22-7 Nodularins
Non-arsenical insecticides (occupational exposures in
spraying and application of)
025038-54-4 Nylon 6
000303-47-9 Ochratoxin A
022966-79-6 Oestradiol mustard
Oestrogen (see Estrogen)
002646-17-5 Oil Orange SS
Opisthorchis felineus (infection with)
Opisthorchis viverrini (infection with)
Oral contraceptives, combined estrogen-progestogen
(see Estrogen-progestogen oral contraceptives)
000523-44-4 Orange I (see CI Acid Orange 20)
001936-15-8 Orange G (see CI Orange G)
000604-75-1 Oxazepam
000129-20-4 Oxyphenbutazone
Painter (occupational exposure as a)
Paint manufacture (occupational exposure in)
012174-11-7 Palygorskite (Attapulgite) (long fibres, > 5 micrometres)
012174-11-7 Palygorskite (Attapulgite)(short fibres, < 5 micrometres)
000794-93-4 Panfuran S (containing dihydroxymethylfuratrizine)
000103-90-2 Paracetamol (Acetaminophen)
010048-32-5 Parasorbic acid
000056-38-2 Parathion
000149-29-1 Patulin
Paving and roofing with coal-tar pitch (see Coal-tar pitch)
000090-65-3 Penicillic acid
057465-28-8 3,4,5,3,4-Pentachlorobiphenyl (PCB-126)
(see Polychlorinated biphenyls, dioxin-like, with a TEF
according to WHO)
24
2B
2B
2A
Volume
Year
17, Sup 7
17, Sup 7
101
1987
1987
in prep
65
1996
3
3
3
2A
48
31, Sup 7
94
53
1990
1987
2010
1991
3
2B
3
19, Sup 7
56
9, Sup 7
1987
1993
1987
2B
3
1
8, Sup 7
61
61, 100B
1987
1994
2012
2B
3
1
3
2B
3
2B
3
3
3
3
66
13, Sup 7
47, 98, 100F
47
68
68
24, Sup 7
73
10, Sup 7
30, Sup 7
40, Sup 7
92
10, Sup 7
100F
1996
1987
2012
1989
1997
1997
1987
1999
1987
1987
1987
2010
1987
2012
3
1

CAS No
Agent
Group
057117-31-4 2,3,4,7,8-Pentachlorodibenzofuran
000076-01-7 Pentachloroethane
000087-86-5 Pentachlorophenol (see Polychlorophenols)
052645-53-1 Permethrin
000198-55-0 Perylene
060102-37-6 Petasitenine
Petroleum refining (occupational exposures in)
Petroleum solvents
Pickled vegetables (traditional in Asia)
000062-44-2 Phenacetin
Phenacetin, analgesic mixtures containing
000085-01-8 Phenanthrene
000136-40-3 Phenazopyridine hydrochloride
000156-51-4 Phenelzine sulfate
000103-03-7 Phenicarbazide
000050-06-6 Phenobarbital
000108-95-2 Phenol
000077-09-8 Phenolphthalein
000063-92-3 Phenoxybenzamine hydrochloride
000050-33-9 Phenylbutazone
000108-45-2 meta-Phenylenediamine
000106-50-3 para-Phenylenediamine
000122-60-1 Phenyl glycidyl ether
000135-88-6 N-Phenyl-2-naphthylamine
000090-43-7 ortho-Phenylphenol
000057-41-0 Phenytoin
105650-23-5 PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)
014596-37-3 Phosphorus-32, as phosphate
000213-46-7 Picene
001918-02-1 Picloram
000051-03-6 Piperonyl butoxide
007440-07-5 Plutonium
053973-98-1 Poligeenan (see Carrageenan, degraded)
009003-01-4 Polyacrylic acid
25
Volume
Year
100F
2012
41, Sup 7, 71
53, 71
53
92
31, Sup 7
45
47
56
24, Sup 7,
100A
1999
1999
1991
2010
1987
1989
1989
1993
2012
Sup 7, 100A
92
24, Sup 7
24, Sup 7
12, Sup 7
79
47, 71
76
24, Sup 7
13, Sup 7
16, Sup 7
16, Sup 7
47, 71
16, Sup 7
73
66
56
78, 100D
92
53
30, Sup 7
78, 100D
2012
2010
1987
1987
1987
2001
1999
2000
1987
1987
1987
1987
1999
1987
1999
1996
1993
2012
2010
1991
1987
2012
19, Sup 7
1987
3
3
3
2A
3
2B
1
1
3
2B
3
3
2B
3
2B
2B
3
3
3
2B
3
3
2B
2B
1
3
3
3
1
3

CAS No
Agent
Group
059536-65-1 Polybrominated biphenyls

supporting evidence from other relevant data, namely
mechanistic similarity with polychlorinated biphenyls
classified in Group 1)
001336-36-3 Polychlorinated biphenyls
009010-98-4
009002-88-4
009016-87-9
009011-14-7
009003-07-0
009003-53-6
009002-84-0
009009-54-5
009003-20-7
009002-89-5
009002-86-2
009003-39-8
003564-09-8
003761-53-3
004548-53-2
023746-34-1
007758-01-2
002955-38-6
029069-24-7
000053-03-2
Polychlorinated biphenyls, dioxin-like, with a Toxicity

Equivalency Factor (TEF) according to WHO (PCBs 77,
81, 105, 114, 118, 123, 126, 156, 157, 167, 169, 189)
strong supporting evidence from other relevant data)
Polychlorinated dibenzo-para-dioxins (other than 2,3,7,8tetrachlorodibenzo-para-dioxin)
Polychlorinated dibenzofurans
(see 2,3,4,7,8-Pentachlorodibenzofuran)
Polychlorophenols and their sodium salts (mixed
exposures)
Polychloroprene
Polyethylene
Polymethylene polyphenyl isocyanate
Polymethyl methacrylate
Polypropylene
Polystyrene
Polytetrafluoroethylene
Polyurethane foams
Polyvinyl acetate
Polyvinyl alcohol
Polyvinyl chloride
Polyvinyl pyrrolidone
Ponceau 3R
Ponceau MX
Ponceau SX
Potassium bis(2-hydroxyethyl)dithiocarbamate
Potassium bromate
Prazepam
Prednimustine
Prednisone
Printing inks
Printing processes (occupational exposures in)
26
Volume
Year
2A
41, Sup 7,
107
in prep
in prep
18, Sup 7,
107
107
69
1997
69
1997
2B
53, 71
1999
3
3
3
3
3
3
3
3
3
3
3
3
2B
2B
3
3
2B
3
3
3
3
2B
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7, 71
8, Sup 7
8, Sup 7
8, Sup 7
12, Sup 7
73
66
50
26, Sup 7
65
65
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1999
1996
1990
1987
1996
1996
in prep

CAS No
Agent
Group
000366-70-1 Procarbazine hydrochloride

Proflavine salts
Progestins
Progestogen-only contraceptives
000051-02-5 Pronetalol hydrochloride
001120-71-4 1,3-Propane sultone
000122-42-9 Propham
000057-57-8 beta-Propiolactone
000627-12-3 n-Propyl carbamate
000115-07-1 Propylene
000075-56-9 Propylene oxide
000051-52-5 Propylthiouracil
087625-62-5 Ptaquiloside
Pulp and paper manufacture
000129-00-0 Pyrene
000110-86-1 Pyridine
085878-62-2 Pyrido[3,4-c]psoralen
000058-14-0 Pyrimethamine
000117-39-5 Quercetin
000106-51-4 para-Quinone
000082-68-8 Quintozene (Pentachloronitrobenzene)
Radiofrequency electromagnetic fields1
Radioiodines, including iodine-131
Radionuclides, alpha-particle-emitting, internally
deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
Radionuclides, beta-particle-emitting, internally deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
013233-32-4 Radium-224 and its decay products
010043-92-2 Radon-222 and its decay products
Refractory ceramic fibres
000050-55-5 Reserpine
27
Volume
2A
26, Sup 7
3
2B
2B
3
2B
3
2B
3
3
2B
2B
3
3
3
3
3
3
3
3
3
2B
1
1
24, Sup 7
Sup 7
72
13, Sup 7
4, Sup 7, 71
12, Sup 7
4, Sup 7, 71
12, Sup 7
60
60
79
40, Sup 7
25, Sup 7
92
77
40, Sup 7
13, Sup 7
73
15, Sup 7, 71
5, Sup 7
102
78, 100D
78, 100D
1
1
1
1
2B
3
Year
1987
1987
1987
1999
1987
1999
1987
1999
1987
1994
1994
2001
1987
1987
2010
2000
1987
1987
1999
1999
1987
in prep
2012
2012
78, 100D
2012
78, 100D
78, 100D
78, 100D
43, 78, 100D
43, 81
24, Sup 7
2012
2012
2012
2012
2002
1987

CAS No
Agent
000108-46-3
000480-54-6
000081-88-9
000989-38-8
023246-96-0
013292-46-1
026308-28-1
Resorcinol
Retrorsine
Rhodamine B
Rhodamine 6G
Riddelliine
Rifampicin
Ripazepam
Rubber manufacturing industry
Group
3
3
3
3
2B
3
3
1
023537-16-8 Rugulosin
Rock (stone) wool
008047-67-4 Saccharated iron oxide
000081-07-2 Saccharin and its salts
000094-59-7 Safrole
Salted fish, Chinese-style
000085-83-6 Scarlet Red
Schistosoma haematobium (infection with)
Schistosoma japonicum (infection with)
Schistosoma mansoni (infection with)
007782-49-2 Selenium and selenium compounds
000563-41-7 Semicarbazide hydrochloride
013909-09-6 Semustine [1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1nitrosourea, Methyl-CCNU]
000480-81-9 Seneciphylline
002318-18-5 Senkirkine
015501-74-3 Sepiolite
068308-34-9 Shale oils
000138-59-0
007631-86-9
014808-60-7
000122-34-9
007758-19-2
000148-18-5
000132-27-4
Shiftwork that involves circadian disruption

Shikimic acid
Silica, amorphous
Silica dust, crystalline, in the form of quartz or cristobalite
Simazine
Slag wool
Sodium chlorite
Sodium diethyldithiocarbamate
Sodium ortho-phenylphenate
28
Volume
Year
1999
1987
1987
1987
2002
1987
1996
2012
3
3
3
3
15, Sup 7, 71
10, Sup 7
16, Sup 7
16, Sup 7
10, Sup 7, 82
24, Sup 7
66
28, Sup 7,
100F
40, Sup 7
43, 81
2, Sup 7
73
2B
1
3
1
2B
3
3
3
1
10, Sup 7
56, 100E
8, Sup 7
61, 100B
61
61
9, Sup 7
12, Sup 7
Sup 7, 100A
1987
2012
1987
2012
1994
1994
1987
1987
2012
10, Sup 7
31, Sup 7
68
35, Sup 7,
100F
98
40, Sup 7
68
68, 100C
73
43, 81
52
12, Sup 7
73
1987
1987
1997
2012
3
3
3
1
2A
3
3
1
3
3
3
3
2B
1987
2002
1987
1999
2010
1987
1997
2012
1999
2002
1991
1987
1999

CAS No
000052-01-7
010048-13-2
018883-66-4
007664-93-9
010098-97-2
000100-42-5
009003-54-7
009003-55-8
000096-09-3
000108-30-5
000842-07-9
003118-97-6
000085-86-9
006416-57-5
006368-72-5
000127-69-5
000095-06-7
000057-68-1
000723-46-6
007446-09-5
000505-60-2
Agent
Group
Solar radiation
Soot (as found in occupational exposure of chimney
sweeps)
Special-purpose fibres such as E-glass and '475' glass
fibres
Spironolactone
Sterigmatocystin
Streptozotocin
Stress (see Volume 100)
Strong-inorganic-acid mists containing sulfuric acid (see
Acid mists)
Strontium-90 (see Fission products)
Styrene
Styrene-acrylonitrile copolymers
Styrene-butadiene copolymers
Styrene-7,8-oxide
Succinic anhydride
Sudan I
Sudan II
Sudan III
Sudan Brown RR
Sudan Red 7B
Sulfafurazole (Sulfisoxazole)
Sulfallate
Sulfamethazine
Sulfamethoxazole
Sulfites
Sulfur dioxide
Sulfur mustard
Sunlamps and sunbeds (see Ultraviolet-emitting tanning

devices)
002783-94-0 Sunset Yellow FCF
29
1
1
Volume
Year
2012
2012
2B
55, 100D
35, Sup 7,
100F
81
3
2B
2B
79
10, Sup 7
17, Sup 7
2001
1987
1987
2B
3
3
2A
60, 82
19, Sup .7
19, Sup 7
60
2002
1987
1987
1994
3
3
3
3
3
3
3
2B
3
15, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
24, Sup 7
30, Sup 7
79
1987
1987
1987
1987
1987
1987
1987
1987
2001
3
3
3
1
79
54
54
9, Sup 7,
100F
2001
1992
1992
2012
8, Sup 7
1987
2002

CAS No
022571-95-5
014807-96-6
014807-96-6
014807-96-6
010540-29-1
001401-55-4
000846-50-4
029767-20-2
008001-50-1
015721-02-5
001746-01-6
000630-20-6
Agent
Group
Surgical implants and other foreign bodies:

- Polymeric implants prepared as thin smooth film (with
the exception of poly(glycolic acid))
- Metallic implants prepared as thin smooth films
- Implanted foreign bodies of metallic cobalt, metallic
nickel and an alloy powder containing 66-67% nickel,
13-16% chromium and 7% iron
Surgical implants and other foreign bodies:
- Organic polymeric materials (as a group)
- Orthopaedic implants of complex composition
- Cardiac pacemakers
- Silicone breast implants
- Implanted foreign bodies of metallic chromium or
titanium and of cobalt-based, chromium-based and
titanium-based alloys, stainless steel and depleted
uranium
- Dental materials
- Ceramic implants
SV40 polyomavirus
Symphytine
Talc containing asbestiform fibres (see Asbestos)
Talc not containing asbestos or asbestiform fibres
Talc-based body powder (perineal use of)
Tamoxifen
(NB: There is also conclusive evidence that tamoxifen
reduces the risk of contralateral breast cancer in breast
cancer patients)
Tannic acid and tannins
Tea
Temazepam
Teniposide
Terpene polychlorinates (Strobane)
2,2',5,5'-Tetrachlorobenzidine
2,3,7,8-Tetrachlorodibenzo-para-dioxin
1,1,1,2-Tetrachloroethane
Year
2B
74
1999
74
1999
3
3
3
2B
1
104
31, Sup 7
42, Sup 7
42, Sup 7, 93
93
66, 100A
3
3
3
2A
10, Sup 7
51
66
76
3
3
1
2B
5, Sup 7
27, Sup 7
69, 100F
41, Sup 7,
71, 106
20, Sup 7,
71, 106
63, 106
30, Sup 7
19, Sup 7, 71
000079-34-5 1,1,2,2-Tetrachloroethane
2B
000127-18-4 Tetrachloroethylene (Perchloroethylene)

022248-79-9 Tetrachlorvinphos
000116-14-3 Tetrafluoroethylene
2A
3
2B
30
Volume
in prep
1987
1987
2010
2010
2012
1987
1991
1996
2000
1987
1987
2012
in prep
in prep
in prep
1987
1999

CAS No
Agent
Group
Volume
Year
3
2B
2B
3
3
2B
2B
1
2B
3
3
1
2B
1
1
1
3
2B
1
3
2B
48, 71
65
48
51
51
7, Sup 7
27, Sup 7
50, 100A
79
79
53
78, 100D
47, 93
89, 100E
83, 100E
83, 100E
47, 71
39, Sup 7, 71
77, 99, 100F
66
79
1999
1996
1990
1991
1991
1987
1987
2012
2001
2001
1991
2012
2010
2012
2012
2012
1999
1999
2012
1996
2001
000299-75-2
Tetrakis(hydroxymethyl)phosphonium salts
Tetranitromethane
Textile manufacturing industry (work in)
Theobromine
Theophylline
Thioacetamide
4,4'-Thiodianiline
Thiotepa
Thiouracil
Thiourea
Thiram
Thorium-232 and its decay products
Titanium dioxide
Tobacco, smokeless
Tobacco smoke, second-hand
Tobacco smoking
Toluene
Toluene diisocyanates
ortho-Toluidine
Toremifene
Toxaphene (Polychlorinated camphenes)
Toxins derived from certain Fusarium species (see
Fusarium)
Treosulfan
2012
000052-68-6
000817-09-4
000076-03-9
000545-06-2
000071-55-6
000079-00-5
000079-01-6
000096-18-4
000102-71-6
001954-28-5
001582-09-8
090370-29-9
000137-17-7
000088-05-1
Trichlorfon
Trichlormethine (Trimustine hydrochloride)
Trichloroacetic acid
Trichloroacetonitrile
1,1,1-Trichloroethane
1,1,2-Trichloroethane
Trichloroethylene
1,2,3-Trichloropropane
Triethanolamine
Triethylene glycol diglycidyl ether
Trifluralin
4,4',6-Trimethylangelicin plus ultraviolet A radiation
2,4,5-Trimethylaniline
2,4,6-Trimethylaniline
3
2B
2B
3
3
3
1
2A
3
3
3
3
3
3
26, Sup 7,
100A
30, Sup 7
50
84, 106
52, 71
20, Sup 7, 71
52, 71
63, 106
63
77
11, Sup 7, 71
53
Sup 7
27, Sup 7
27, Sup 7
000509-14-8
000083-67-0
000058-55-9
000062-55-5
000139-65-1
000052-24-4
000141-90-2
000062-56-6
000137-26-8
007440-29-1
013463-67-7
000108-88-3
026471-62-5
000095-53-4
089778-26-7
008001-35-2
31
1987
1990
in prep
1999
1999
1999
in prep
1995
2000
1999
1991
1987
1987
1987

CAS No
Agent
003902-71-4
000118-96-7
000217-59-4
000068-76-8
000545-55-1
000051-18-3
000115-96-8
038571-73-2
000126-72-7
4,5',8-Trimethylpsoralen
2,4,6-Trinitrotoluene
Triphenylene
Tris(aziridinyl)-para-benzoquinone (Triaziquone)
Tris(1-aziridinyl)phosphine oxide
2,4,6-Tris(1-aziridinyl)-s-triazine
Tris(2-chloroethyl) phosphate
1,2,3-Tris(chloromethoxy)propane
Tris(2,3-dibromopropyl) phosphate
Tris(2-methyl-1-aziridinyl)phosphine oxide
Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
Trypan blue
Tungsten carbide with cobalt metal (see Cobalt metal
with tungsten carbide)
000057-39-6
062450-06-0
062450-07-1
000072-57-1
012070-12-1
007440-48-4
000066-75-1
001314-62-1
000128-66-5
000143-67-9
002068-78-2
000108-05-4
000593-60-2
000075-01-4
009003-22-9
000100-40-3
000106-87-6
Group
Ultraviolet radiation (wavelengths 100-400 nm,

encompassing UVA, UVB, and UVC)
Ultraviolet-emitting tanning devices
Uracil mustard
Urethane (see Ethyl carbamate)
Vanadium pentoxide
Vat Yellow 4
Vinblastine sulfate
Vincristine sulfate
Vinyl acetate
Vinyl bromide
(NB: (1) Overall evaluation upgraded to Group 2A
based on mechanistic and other relevant data;
(2) For practical purposes, vinyl bromide should be
considered to act similarly to the human carcinogen
vinyl chloride.)
Vinyl chloride
Vinyl chloride-vinyl acetate copolymers
4-Vinylcyclohexene
4-Vinylcyclohexene diepoxide
32
Volume
Year
3
3
3
3
3
3
3
3
2A
40, Sup 7
65
92
9, Sup 7
9, Sup 7
9, Sup 7
48, 71
15, Sup 7, 71
20, Sup 7, 71
1987
1996
2010
1987
1987
1987
1999
1999
1999
3
2B
2B
2B
9, Sup 7
31, Sup 7
31, Sup 7
8, Sup 7
1987
1987
1987
1987
100D
2012
1
2B
100D
9, Sup 7
2012
1987
2B
3
3
3
2B
2A
86
48
26, Sup 7
26, Sup 7
63
39, Sup 7,
71, 97
2006
1990
1987
1987
1995
2008
1
3
2B
2B
97, 100F
19, Sup 7
60
60
2012
1987
1994
1994

CAS No
Agent
000075-02-5 Vinyl fluoride

(NB: (1) Overall evaluation upgraded to Group 2A
based on mechanistic and other relevant data;
(2) For practical purposes, vinyl fluoride should be
considered to act similarly to the human carcinogen
vinyl chloride.)
000075-35-4 Vinylidene chloride
009011-06-7 Vinylidene chloride-vinyl chloride copolymers
000075-38-7 Vinylidene fluoride
000088-12-0 N-Vinyl-2-pyrrolidone
025013-15-4 Vinyl toluene
012001-79-5 Vitamin K substances
Welding fumes
(NB: Volume 100D concluded that there is sufficient
evidence for ocular melanoma in welders)
013983-17-0 Wollastonite
Wood dust
Wood smoke (see Biomass fuel, indoor emissions from
household combustion)
X- and Gamma-Radiation
001330-20-7 Xylenes
000095-68-1 2,4-Xylidine
000095-78-3 2,5-Xylidine
000085-84-7 Yellow AB
000131-79-3 Yellow OB
007481-89-2 Zalcitabine
000315-18-4 Zectran
001318-02-1 Zeolites other than erionite (clinoptilolite,
phillipsite,mordenite, non-fibrous Japanese zeolite,
synthetic zeolites)
030516-87-1 Zidovudine (AZT)
012122-67-7 Zineb
000137-30-4 Ziram
1
Includes radiofrequency electromagnetic fields from wireless phones
Last update: 10 April 2013
33
Group
Volume
Year
2A
63, 97
2008
3
3
3
3
3
3
2B
39, Sup 7, 71
19, Sup 7
39, Sup 7, 71
19, Sup 7, 71
60
76
49
1999
1987
1999
1999
1994
2000
1990
3
1
68
62, 100C
1997
2012
1
3
3
3
3
3
2B
3
3
75, 100D
47, 71
16, Sup 7
16, Sup 7
8, Sup 7
8, Sup 7
76
12, Sup 7
68
2012
1999
1987
1987
1987
1987
2000
1987
1997
2B
3
3
76
12, Sup 7
53
2000
1987
1991

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Agents Classified by the IARC Monographs, Volumes 1107