DRUG STUDY

DRUG NAME GENERIC NAME:

Paracetamol

CLASSIFICATION MECHANISM OF ACTION

Analgesic Inhibits CNS prostaglandin synthesis with minimal effects on peripheral prostaglandin synthesis

INDICATION
Symptomatic relief of pain

CONTRAINDICATION SIDE EFFECTS

Renal Insufficiency Anemia Allergy to the drug Minimal GI upset Constipation Drowsiness Liver Damage

NURSING RESPONSIBILITIES
Take with food or milk to minimize GI upset. Raise siderails Advise patient too much intake may cause liver.

BRAND NAME:
Biogesic

DOSAGE:
500 mg 1 tab for 4 hrs. PRN

DRUG NAME GENERIC NAME:

Metformin

CLASSIFICATION MECHANISM OF ACTION

Hormone and synthetic substitute; antidiabetic Decreases Hepatic Glucose production, decreases Intestinal absorption of glucose, and Increases Peripheral uptake and utilization of glucose.

INDICATION
Treatment for type 2 diabetic clients.

CONTRAINDICATION SIDE EFFECTS

Hypersensitivity to the drug. Renal disease or dysfunction. Alcoholism Acute or chronic acidosis. Abnormal hepatic function Hypoglycemia

NURSING RESPONSIBILITIES
Monitor blood glucose level periodically. Tell patient it will cause a metallic taste: should subside. Consume Plenty of fluids; report when vomiting is severe. Take in with food to decrease GI upset.

BRAND NAME:
Glucophage

Causes metallic taste \ Nausea and Vomiting Abdominal discomfort or pain Flatulence

DOSAGE:
500 mg 1tab After meals

DRUG NAME
GENERIC NAME: Coamoxiclav

CLASSIFICATION MECHANISM OF ACTION

Penicillin B-lactam antibiotic w/ Blactamase inhibitor Spectrum. Augmentin works by inhibiting the synthesis of bacterial cell walls.

INDICATION
Acute exacerbations of chronic bronchitis (adequately diagnosed) Community acquired pneumonia Cystitis Pyelonephritis Bone and joint infections, in particular osteomyelitis Intra-abdominal infections Female genital infections.

CONTRAINDICATION SIDE EFFECTS

Hypersensitivity History of Jaundice or hepatic dysfunction associated with amoxicillin/clauvan ate. Severe renal impairment. Diarrhea Nausea and vomiting Rash Itching/Swelling

NURSING RESPONSIBILITIES
Take medicine with food. Notify physician.

BRAND NAME: Augmentin DOSAGE: 1 gm IV for 12 hrs.

DRUG NAME
GENERIC NAME: Saxagliptin

CLASSIFICATION MECHANISM INDICATION CONTRAINDICATION SIDE OF ACTION EFFECTS

Dipeptidyl peptidase 4 inhibitors Inhibits the breakdown of incretin hormones [glucagon-like peptide-1 (GLP1) and glucosedependent insulinotropic polypeptide (GIP)]. Prescribed for Type 2 diabetes. Patients with Type 1 diabetes. High blood ketone levels. Hypersensitivity. Hypoglycemia Acute pancreatitis

NURSING RESPONSIBILITIES
Monitor blood sugar level. Observe carefully for s/s of pancreatitis; if suspected discontinue drug administration.

BRAND NAME: Onglyza DOSAGE: 2.5g 1 tab Daily after breakfast

DRUG NAME
GENERIC NAME: Pioglitazone BRAND NAME: Actos

CLASSIFICATION MECHANISM OF ACTION

Antidiabetic Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver.

INDICATION
Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

CONTRAINDICATION SIDE EFFECTS

Hypersensitivity to the drug. Congestive heart failure Liver problems Low blood sugar Dizziness

NURSING RESPONSIBILITIES
Avoid activities that requires alertness. Take once daily regarding to meals.

Increase risk for bone fracture in women Nausea and vomiting, loss of appetite, lack of energy.

DOSAGE: 15 mg tab daily After lunch

Discontinue administration of the drug.

DRUG NAME

CLASSIFICATION MECHANISM INDICATION OF ACTION

Suppresses gastric acid secretion by inhibiting the H+, K+-ATPase enzyme system [the acid (proton H+) pump] in the parietal cells. Indicated for shortterm active duodenal ulcer. Short-term active benign active ulcer. treatment of heartburn and other symptoms associated with GERD(Gastroesophag eal Reflux Disease)

CONTRAINDICATION SIDE EFFECTS

Lactation Use as a long term drug for duodenal ulcer disease. Abdominal pain. Diarrhea Nausea and vomiting. Dizziness Rash

NURSING RESPONSIBILITIES
Ask client to report any changes in urinary elimination, pain or discomfort. Avoid alcohol and OTC agents as well as foods known to cause GI upset. Avoid activities that require mental alertness. Ask client if allergic to the drug.

GENERIC Proton pump inhibitor NAME: Omeprazole BRAND NAME: Prilosec

DOSAGE: 1 tab Once a day

DRUG NAME
GENERIC NAME: Amlodipine + Telmisartan BRAND NAME: Twynsta

CLASSIFICATION MECHANISM OF ACTION

Calcium channel blocker and an angiotensin II receptor antagonist. Amlodipine as a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle and Telmisartan blocks the vasoconstrictor and aldosteronesecreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues

INDICATION

CONTRAINDICATION SIDE EFFECTS NURSING RESPONSIBILITIES

Hypersensitivity on both components of the drug. Pregnancy and lactation. Presence of biliary obstruction. Dizziness and lightheadedne ss. Diarrhea Vomiting Low blood pressure Edema Advise patient to rise up slowly from the bed. Report prolonged diarrhea and vomiting to the physician. Monitor Blood pressure.

Hypertension

DOSAGE: 1 Tab daily