Tumor marker

Associated tumor types

Alpha fetoprotein (AF germ cell tumor, hepatocellular carcinoma[5] P)

CA15-3

breast cancer[6]

CA27-29

breast cancer

CA19-9

Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer.[7]

CA-125

Mainly ovarian cancer,[8] but may also be elevated in for example endometrial cancer, fallopian tube cancer,lung cancer, breast cancer and gastrointestinal cancer.[9] May also increase in endometriosis.[10]

Calretinin

mesothelioma, sex cord-gonadal stromal tumour, adrenocortical carcinoma, synovial sarcoma[5]

Carcinoembryo gastrointestinal cancer, cervix cancer, lung cancer, ovarian nic antigen cancer, breast cancer, urinary tract cancer[5]

CD34

hemangiopericytoma/solitary fibrous tumor, pleomorphic lipoma, gastrointestinal stromal tumor,dermatofibrosarcoma protuberans[5]

CD99

Ewing sarcoma, primitive neuroectodermal tumor, hemangiopericytoma/solitary fibrous tumor, synovial

sarcoma, lymphoma, leukemia, sex cord-gonadal stromal tumour[5]

CD117

gastrointestinal stromal tumor, mastocytosis, seminoma[5]

Chromogranin

neuroendocrine tumor[5]

Cytokeratin (var Many types of carcinoma, some types of sarcoma[5] ious types)

Desmin

smooth muscle sarcoma, skeletal muscle sarcoma, endometrial stromal sarcoma[5]

Epithelial membrane protein (EMA)

many types of carcinoma, meningioma, some types of sarcoma[5]

Factor vascular sarcoma[5] VIII, CD31 FL1

Glial fibrillary acidic glioma (astrocytoma, ependymoma)[5] protein (GFAP)

Gross cystic disease fluid breast cancer, ovarian cancer, salivary gland cancer[5] protein (GCDF P-15)

HMB-45

melanoma, PEComa (for example angiomyolipoma), clear cell carcinoma, adrenocortical carcinoma[5]

Human chorionic gestational trophoblastic disease, germ cell tumor, carcinoma[5] gonadotropin (h CG)

immunoglobulin lymphoma, leukemia[5]

inhibin

sex cord-gonadal stromal tumour, adrenocortical carcinoma, hemangioblastoma[5]

keratin (various carcinoma, some types of sarcoma[5] types)

PTPRC (CD45) lymphoma, leukemia, histiocytic tumor[5]

lymphocyte marker(various lymphoma, leukemia[5] types

MART1 (Melan-A)

melanoma, steroid-producing tumors (adrenocortical carcinoma, gonadal tumor)[5]

Myo D1

rhabdomyosarcoma, small, round, blue cell tumour[5]

muscle-specific myosarcoma (leiomyosarcoma, rhabdomyosarcoma)[5] actin(MSA)

neurofilament

neuroendocrine tumor, small-cell carcinoma of the lung[5]

neuron-specific neuroendocrine tumor, small-cell carcinoma of the lung, breast enolase (NSE) cancer[5]

placental alkaline seminoma, dysgerminoma, embryonal carcinoma[5] phosphatase (P LAP)

prostateprostate[5] specific antigen

S100 protein

melanoma, sarcoma (neurosarcoma, lipoma, chondrosarcoma), astroc ytoma, gastrointestinal stromal tumor, salivary gland cancer, some types of adenocarcinoma, histiocytic tumor (dendritic cell,macrophage)[5]

smooth muscle gastrointestinal stromal tumor, leiomyosarcoma, PEComa[5] actin(SMA)

synaptophysin

neuroendocrine tumor[5]

thyroglobulin

thyroid cancer (but not in medullary thyroid cancer)[5]

thyroid transcription factor-1

all types of thyroid cancer, lung cancer[5]

Tumor M2-PK

colorectal cancer,[11] Breast cancer,[12][13] renal cell carcinoma[14][15] Lung cancer,[16][17] Pancreatic cancer,[18] Esophageal Cancer,[19] Stomach Cancer,[19]Cervical Cancer,[20] Ovarian Cancer,[21]

vimentin

sarcoma, renal cell carcinoma, endometrial cancer, lung carcinoma, lymphoma, leukemia, melanoma[5]