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    chapter 7

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
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    27 views58 pages

    Chap 7 S

    Uploaded by

    Bradley Christmas
    chapter 7

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 58

    Essential Cell Biology

    Third Edition

    Chapter 7 From DNA to Protein: How Cells Read the Genome



    Copyright Garland Science 2010

    The Interna*onal Gene*cally Engineered Machine (iGEM) Compe**on is a worldwide Synthe*c Biology compe**on aimed at undergraduate university students.

    130 Teams
    In 2010!
    (but no UCSB )

    Summary of Achievements

    Characterization of new  mammalian activators & repressors
    Complex mammalian  logic circuit

    Computational design of multicellular behavior


    Adhesion of mammalian cells


    Engineering of Notch-Delta communication system


    Figure 7-1 Essential Cell Biology ( Garland Science 2010)

    NOTE: [mRNA] weakly correlates


    with [protein]

    Figure 7-2 Essential Cell Biology ( Garland Science 2010)

    DNA Microarrays Can be Used to Measure mRNA species Abundance

    There are two primary differences between DNA and RNA


    Figure 7-3 Essential Cell Biology ( Garland Science 2010)

    Figure 7-5 Essential Cell Biology ( Garland Science 2010)

    Table 7-4 Essential Cell Biology ( Garland Science 2010)

    Figure 7-7 Essential Cell Biology ( Garland Science 2010)

    Efcient transcription enables many transcripts to be made from one gene simultaneously

    Figure 7-8 Essential Cell Biology ( Garland Science 2010)

    Table 7-1 Essential Cell Biology ( Garland Science 2010)

    In bacteria sigma factors direct RNApol to promoters


    Figure 7-9 Essential Cell Biology ( Garland Science 2010)

    The sequence features of promoters are conserved


    Figure 7-10 Essential Cell Biology ( Garland Science 2010)

    Consensus -10 and -35 sequences


    Figure 7-11 Essential Cell Biology ( Garland Science 2010)

    Table 7-2 Essential Cell Biology ( Garland Science 2010)

    Figure 7-12 Essential Cell Biology ( Garland Science 2010)

    Figure 7-13 Essential Cell Biology ( Garland Science 2010)

    Figure 7-14 Essential Cell Biology ( Garland Science 2010)

    Figure 7-16a Essential Cell Biology ( Garland Science 2010)

    Figure 7-16b Essential Cell Biology ( Garland Science 2010)

    Figure 7-17 Essential Cell Biology ( Garland Science 2010)

    Figure 7-18 Essential Cell Biology ( Garland Science 2010)

    Figure 7-20 Essential Cell Biology ( Garland Science 2010)

    Figure 7-21 Essential Cell Biology ( Garland Science 2010)

    Figure 7-22 Essential Cell Biology ( Garland Science 2010)

    Figure 7- 23a Essential Cell Biology ( Garland Science 2010)

    Figure 7-23b Essential Cell Biology ( Garland Science 2010)

    Figure 7-24 Essential Cell Biology ( Garland Science 2010)

    Figure 7-25 Essential Cell Biology ( Garland Science 2010)

    Figure 7-28 Essential Cell Biology ( Garland Science 2010)

    Figure 7-29 (part 1 of 2) Essential Cell Biology ( Garland Science 2010)

    Figure 7-29 (part 2 of 2) Essential Cell Biology ( Garland Science 2010)

    Figure 7-30 Essential Cell Biology ( Garland Science 2010)

    Figure 7-31 Essential Cell Biology ( Garland Science 2010)

    Figure 7-32 Essential Cell Biology ( Garland Science 2010)

    Figure 7-33 (part 2 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-33 (part 3 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-33 (part 4 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-33 (part 5 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-34 Essential Cell Biology ( Garland Science 2010)

    Figure 7-35 (part 1 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-35 (part 2 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-35 (part 3 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-35 (part 4 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-35 (part 5 of 5) Essential Cell Biology ( Garland Science 2010)

    Figure 7-36 Essential Cell Biology ( Garland Science 2010)

    Figure 7-37 Essential Cell Biology ( Garland Science 2010)

    Figure 7-37 (part 1 of 3) Essential Cell Biology ( Garland Science 2010)

    Figure 7-37 (part 2 of 3) Essential Cell Biology ( Garland Science 2010)

    Figure 7-37 (part 3 of 3) Essential Cell Biology ( Garland Science 2010)

    Figure 7-38 Essential Cell Biology ( Garland Science 2010)

    Ribosomes are recruited to the Kozak Sequence


    Table 7-3 Essential Cell Biology ( Garland Science 2010)

    Figure 7-40 Essential Cell Biology ( Garland Science 2010)

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