Liver As Endocrine - Stuart White

Dr.
Stuart White July 26, 2012

1
Mentoring the Mentors
1
Mentoring the Mentor Mentoring the Mentor
Stuart White, DC, DACBN, CCN
Whole Health Associates
1406 Vermont
Houston, Texas 77006
713/522-6336
stuartwhite@wholehealthassoc.com
www.wholehealthassoc.com
www.doctorofthefuture.org
2
Mentor goals:
! To declare what is possible and establish a
commitment to that possibility
! Address personal and professional barriers
limiting the ability to serve
! Evolution of vision/mission/ethics that drive
success
! Create immediate action steps to apply
learning and growth
! Construct the round table of applied
trophologists
3
Mentoring the mentor:
! Who are the mentors? Practitioners
! Who are we mentoring? Patients and
GAP
! Whats the purpose? Optimized life
! How does it work? Whatever you
learn you teach someone else (anyone
else)
! Whos is included? Self selection, you
pick yourself
Page 1
Dr. Stuart White July 26, 2012
4
10
7 Pillars of Healing
7 Unified Mechanisms of Health
!Endocrine/Hormonal
!Glycemic Management
!pH Bioterrain
!Inflammatory status
!Immune burdens
!Circulatory Status
!Digestive Potency
11
1 -The Endocrine Axis
!Systemic activation of healing and
repair
!7 glandular levels
!Estrogen dominance is due to
deficient liver cleansing promote
Phase I & II detoxification
!PMGs first, liver support second,
lifestyle modification third, herbal
support fourth, HRT final step
12 12 12 12
Stressors Stressors Stressors Stressors Hormonal/endocrine Hormonal/endocrine Hormonal/endocrine Hormonal/endocrine adaptation adaptation adaptation adaptation Glandularfatigue & i mbalance Glandularfatigue & i mbalance Glandularfatigue & i mbalance Glandularfatigue & i mbalance
Depletion of organ reserve andnutrient/mineral substrates Depletion of organ reserve andnutrient/mineral substrates Depletion of organ reserve andnutrient/mineral substrates Depletion of organ reserve andnutrient/mineral substrates
Reduced homeostatic mechanisms Reduced homeostatic mechanisms Reduced homeostatic mechanisms Reduced homeostatic mechanisms
Enhanced physiology/personality Enhanced physiology/personality Enhanced physiology/personality Enhanced physiology/personality
#1 Core Physiologic Principle #1 Core Physiologic Principle #1 Core Physiologic Principle #1 Core Physiologic Principle
Stress hyper/hypo reactivity Stress hyper/hypo reactivity Stress hyper/hypo reactivity Stress hyper/hypo reactivity
Altered psychoneuroimmunologicmechanisms Altered psychoneuroimmunologicmechanisms Altered psychoneuroimmunologicmechanisms Altered psychoneuroimmunologicmechanisms
Restoredadaptivemechanisms Restoredadaptivemechanisms Restoredadaptivemechanisms Restoredadaptivemechanisms
Symptoms Symptoms Symptoms Symptoms physical/personality modulation physical/personality modulation physical/personality modulation physical/personality modulation Increasedglandular strength/resilience Increasedglandular strength/resilience Increasedglandular strength/resilience Increasedglandular strength/resilience
Diseasediagnosis Diseasediagnosis Diseasediagnosis Diseasediagnosis chronic progression chronic progression chronic progression chronic progression
Medical Intervention Medical Intervention Medical Intervention Medical Intervention Drugs & Surgery Drugs & Surgery Drugs & Surgery Drugs & Surgery Increasedorgan reserve Increasedorgan reserve Increasedorgan reserve Increasedorgan reserve repletion of substrates repletion of substrates repletion of substrates repletion of substrates
Death Death Death Death
Nutrient Nutrient Nutrient Nutrient
repletion repletion repletion repletion
target target target target
fortification fortification fortification fortification
Page 2
5
13
14
Liver as endocrine:
! The liver is essential to endocrine health as it
breaks down conjugated hormones promoting a
more accurate body concept of hormonal status
! Estrogen dominance is conceptually seen as a
reduction of estrogen synthesis due to a
misperceived of abundance when it is not being
broken down by the liver this of course results in a
secondary reduction of progesterone production
due to the reduced effect of priming the
progesterone receptors by estrogen
! The health and efficiency of the liver directly
participates in hormonal balance in this way
15
Liver as endocrine:
! The liver also synthesizes protein bound iodine
which in turn promotes thyroid physiology, so many
thyroid imbalances are up-regulated by increasing
liver activity
! To attempt to define the livers function if futile as it
has been estimated at having over 30,000 individual
actions
! So rather than trying to describe and support so
many different functions it is wiser to view the liver
status as essential to overall endocrine balance
! For this reason to achieve balancing endocrine
activity in anyone the liver must be supported and
addressed
Page 3
6
16
Liver Where to begin:
! One of the most popular starting places doctors
choose to begin modulating health function is with
the SP Purification Program (21 days) this is in
fact a liver detox and unburdening program
specifically promoting both Phase I and II
detoxification the liver is cleansed, weight is
reduced, and a metabolic/endocrine reboot is
accomplished
! There are many other ways to gradually and
incrementally up-regulate liver status that can be
considered as an ongoing way to promote health
and transformation
17
Liver sequentially enhanced:
! A F Betafood
! Choline
! Betacol
! Livaplex
! Livco
! Livton
! Albizia
! Parasite cleansing (Zymex II, Multizyme,
Wormwood)
18
Liver cleansing step by step:
! A F Betafood 10/day - cholagogue promoting bile
synthesis and delivery
! Choline 6/day begin second month with A F
Betafood and further emulsify fats and therefore bile
action
! Betacol 6/day Follow A F Betafood program with
this promoting cleansing of highly alkaline guanidine
from liver
! Collinsonia Root 6/day Promotes increased
vascular dilation in hepatic and peripheral
circulation very useful in reducing liver congestion
Page 4
7
19
Liver cleansing step by step:
! Livaplex 6/day combination product including A
F Betafood, Hepatrophin, Betacol, Spanish Black
Radish, Chezyn, Antronex used for general liver
support and cleansing and may be seen as a next
step to liver sequential up-regulation
! Livco 4/day Promotes Phase I & II detoxification
and helps with viral burdens in the liver
! Livton 4/day Promotes bile production and
delivery (cholagogue) supporting normal digestive
actions and preventing bile and bowel stasis
! Albizia 4/day Supports the Kupfer cells in the
liver which release histamine and thus reduce
histaminic burden and body sensitivity
Estrogen Dominance - Widespread
! Defined as deficient, normal, or excessive levels of
estrogen with too little progesterone to balance the
estrogen common in both cycling and menopausal
women, and andropausal men
!Caused by cortisol(pregnenelone) steal, HRT & BC pill,
adrenal fatigue, hypothyroidism, high glycemic diet, trans-
fatty acids, xenoestrogens, obesity (estrogen is made in
the fat cells)
!Symptoms may include: anxiety, anger, agitation, mood
swings, depression, dysmenorrhea, water retention,
fibrocystic breasts & tenderness, migraines, food
cravings, fibromyalgic discomfort, acne, loss of
mentation, mid-body fat gain, cold extremities (estrogen
blocks thyroid), dysglycemia, loss of libido, infertility,
insomnia, osteoporosis, PCOS, uterine fibroids,
autoimmunity, breast or uterine cancer
Estrogen Ultimate Phase I/II Detoxification
! For hormones to dance with other hormones it must have a flexible
response pattern = be able to increase/decrease rapidly
! Estrogen building up imbalances menstruation, pregnancy, lactation
(following menopause dance continues to prolong life, supporting structural,
cardiac, and neurological functions)
! Cytochrome P450 enzyme system is used to eliminate drugs, toxins,
unwanted substances, biological agents, and estrogens body views
estrogen as a toxin because it allows such a small number of estrogen
molecules to be active, unlike testosterone, DHEA, progesterone
! Phase I (P450) oxidation, reduction, hydrolysis, hydration, dehalogenation
= increased polarity, less lipid-soluble, reactive oxygen intermediates with
potential for secondary tissue damage sticky reactive molecules
(antioxidant needs)
! Phase II sulfation, methylation, glucuronidation = polar water-soluble bile
and urine (sulfation, homocysteine support, and gut symbiotic bacteria +
soluble fiber are essential fuels)
! Phase III (Antiporter) a recirculation process not yet accepted scientifically,
active efflux pump decreasing intracellular concentration of xenobitoics
allowing for a second-pass with the detox enzymes located at or near the
cell membrane (more concentrated presence in cancer cells, liver, kidney,
pancreas, intestines, brain, testes)
Page 5
8
Detox Phase I & II
Textbook of Functional Medicine: David S. Jones, Institute for Functional Medicine: Gig Harbor, WA.: Page 278
23
Effects of Estrogens
!Tissue Proliferative
Effects
!Breast tissue proliferation
!Vaginal tissue
proliferation
!Skin, nail, and hair
proliferation
!Parietal cells (HCL)
!Other Effects
!Antagonist effects on
proinflammatory
transcriptional factors
!Modulation of nitric oxide
!Direct antioxidative
effects
!Immune system
modulation
24
Conditions that Increase in Risk with
Perimenopause and Menopause
!Cardiovascular Disease and Stroke
!Osteoporosis
!Dementia and Alzheimers
!Arthritis
!Autoimmune Disease
Page 6
9
25
!If there is a decline in
estradiol levels in a female
patient in perimenopause the
inflammatory cytokine system
is upregulated and may stay
upregulated even after
estrogen levels are restored.
Phase I & II
detoxification
occur
principally in
the liver, while
Phase I, II, &
III occur in
every cell the
liver
determines the
foundational
capacity to
cleanse
27
The secret formula for encouraging a healthy 2 to 16 ratio
! 1-O-FERULOYL-BETA-D-GLUCOSE Leaf:
! 1-O-P-COUMAROYL-BETA-D-GLUCOSE Leaf:
! 1-O-P-SINAPOYL-BETA-D-GLUCOSE Leaf:
! 2-HYDROXY-BUT-3-ENYL-GLUCOSINOLATE Leaf:
! 4-METHOXY-INDOL-3-YL-METHYL-GLUCOSINOLATE Leaf:
! ALLYL-ISOTHIOCYANATE Seed:
! ALPHA-LINOLENIC-ACID Leaf 990 - 7,069 ppm
! ALPHA-TOCOPHEROL Leaf 4 - 63 ppm
! ANTEISO-HEPTACOSAN-1-OL Fl ower:
! ANTEISO-MONTANYL-ALCOHOL Leaf:
! ANTEPENTACOSAN-1-OL Leaf:
! ARACHIDONIC-ACID Leaf 10 - 71 ppm
! ARGININE Leaf 2,030 - 14,494 ppm
! ASCORBIC-ACID Leaf 720 - 6,069 ppm
! ASHLeaf 13,700 - 97,818 ppm
! BETA-CAROTENE Leaf 5 - 41 ppm
! BORONLeaf 57 ppm; Stem 21 ppm;
! CAFFEIC-ACID Leaf 34 ppm;
! CALCIUM Leaf 395 - 3,177 ppm
! CARBOHYDRATES Leaf 89,600 - 639,744 ppm
! CITRIC-ACID Leaf:
! COPPERLeaf 1 - 5 ppm
! COUMESTROL Shoot 400 ppm;
! CYSTINE Leaf 220 - 1,571 ppm
! FAT Leaf 2,000 - 28,560 ppm
! FERULIC-ACID Leaf 10 ppm;
! FIBERLeaf 15,100 - 107,814 ppm
! FOLACINLeaf 0.56 - 4 ppm
! FUMARIC-ACID Leaf:
! HEPTACOSAN-1-OL Fl ower:
! HEXACOSAN-1-OL Leaf:
! HISTIDINE Leaf 760 - 5,426 ppm
! INDOLE-3-ACETONITRILE Shoot:
! INDOLE-3-CARBINOL Shoot:
! INDOLE-3-CARBOXALDEHYDE Shoot:
! INDOLE-3-CARBOXYLIC-ACID Shoot:
! INDOYL-3,3'-DIMETHANE-CARBOXYLIC-ACID Shoot:
! IRONLeaf 9 - 136 ppm
! ISOHEXACOSAN-1-OL Leaf:
! ISOLEUCINE Leaf 1,320 - 9,425 ppm
! ISOOCTACOSAN-1-OL Leaf:
! KILOCALORIES Leaf 430 - 3,070 /kg
! LEUCINE Leaf 1,520 - 10,853 ppm
! LINOLEIC-ACIDLeaf 450 - 3,213 ppm
! LYSINE Leaf 1,540 - 10,996 ppm
ISOHEXACOSAN-1-OL Leaf:
ISOLEUCINE Leaf 1,320 - 9,425 ppm
ISOOCTACOSAN-1-OL Leaf:
KILOCALORIES Leaf 430 - 3,070 /kg
LEUCINE Leaf 1,520 - 10,853 ppm
LINOLEIC-ACIDLeaf 450 - 3,213 ppm
LYSINE Leaf 1,540 - 10,996 ppm
MAGNESIUM Leaf 230 - 1,642 ppm
MALIC-ACIDLeaf:
MANGANESE Leaf 3 - 24 ppm
METHIONINE Leaf 320 - 2,285 ppm
MOLYBDENUM Leaf 0.9 ppm; Stem 0.36 ppm;
MONTANYL-ALCOHOL Leaf:
NIACIN Leaf 6 - 64 ppm
OCTACOSAN-1-OL Leaf:
OLEIC-ACIDLeaf 190 - 1,357 ppm
OXALATE Leaf 3,600 - 25,704 ppm
P-COUMARIC-ACID Leaf 12 ppm;
PALMITIC-ACIDLeaf 530 - 3,784 ppm
PALMITOLEIC-ACIDLeaf 20 - 142 ppm
PANTOTHENIC-ACIDLeaf 3.1 - 22 ppm
PENTACOSAN-1-OL Leaf:
PHENYLALANINE Leaf 980 - 6,997 ppm
PHOSPHORUS Leaf 690 - 4,927 ppm
PHYTOSTEROLS Leaf 240 - 1,710 ppm
POTASSIUM Leaf 3,670 - 29,343 ppm
PROP-2-ENYL-GLUCOSINOLATE Leaf:
PROTEINLeaf 32,580 - 250,000 ppm
QUERCETINSprout Seedl i ng 25 ppm;
QUINIC-ACID Leaf:
RIBOFLAVINLeaf 0.4 - 10 ppm
RUTINShoot 20 ppm;
SEC-BUTYL-ISOTHIOCYANATE Seed:
SELENIUM Leaf 0.024 ppm; Stem0.012 ppm;
SINAPIC-ACID Leaf 107 ppm;
SODIUM Leaf 221 - 1,990 ppm
STEARIC-ACIDLeaf 30 - 214 ppm
SUCCINIC-ACID Leaf:
TETRACOSAN-1-OL Leaf:
THIAMINLeaf 1.3 - 11 ppm
THREONINE Leaf 1,200 - 8,568 ppm
TRIACONTAN-1-OL Leaf:
TRYPTOPHANLeaf 370 - 2,642 ppm
VALINE Leaf 1,550 - 11,067 ppm
VIT-B-6 Leaf 2.2 - 16 ppm
WATERLeaf 846,000 - 945,500 ppm
ZINC Leaf 10 - 157 ppm
Brussel Sprouts
Cruciferous Complete
Page 7
10
Detox Phase I & II
Textbook of Functional Medicine: David S. Jones, Institute for Functional Medicine: Gig Harbor, WA.: Page 278
Needs
Homocysteine
support, B2, B3,
B6, Glutathione,
AA, Flavonoids,
Phospholipids
Needs
Homocysteine
support, Glycine,
Taurine,
Glutamine, NAC,
Cysteine,
Methionine
Stepping Forward
It is doing and not simply knowing
Risking based on reason
Passion because of possibility
30
Case Study Steve
Auto-immune resolution
! 37 years old,
Page 8
11
Megan Autoimmune, ADD, Addict
!Presented 10/10 for IBS, Rheumatoid Arthritis, ADD
and insomnia. Tried everything and finally ended up
taking methyltrexate, Vivance and Folic Acid
Symptom free in two months, and in five months no
longer wants to smoke no suggestions just
biochemical platform to live from
!Biochemistry changes the choices we think we are
making
32
Bone health
A circulatory perspective:
! The classic view of osteoarthritis(OA) and bone
health status is based on the concept of
demineralization and yet this does not address the
localized effect of OA and the resistive response in
the nutritional patient
! So this discussion will speculate about a different
etiology for OA and bone health which does seem
to respond quickly to nutritional intervention
! This is first based on ideas elaborated by Kerry
Bone and subsequent application of these
perspectives clinically with many patients and
outcomes observed
33
Bone circulation:
! An Australian researcher was developing a large
computer model database he queried it with
certain risk factors known to associate with the
typical vascular issues of incidence in the society
(e.g. Type A personality, smoking) he expected
the computer model to show a certain percentage of
vascular heart disease it did but it also revealed
an incidence of OA 400% greater than CAD so he
sought cadaver confirmation of what the statistics
were suggesting
! The osseous microvasculature supplying blood to
the bone was plaqued and blocked in OA
suggesting a loss of nutrient supply to the bone for
ongoing osteoblastic buildup
Page 9
12
34
Bone circulation:
! This in turn resulted in a osteonecrosis and bone
compression and then the characteristic
hypertrophic lipping and spurring in response
! Because the vascular pathways supplying blood to
bone is through hard channels incapable of dilation
the bone clinically shows vascular obstruction 4
times more than the heart
! So with vascular renewal programs and oral
chelation efforts reduction in OA symptoms are able
to be observed within 3-4 weeks, with therapeutic
intervention requiring 3-6 months to achieve
maximal improvement
! Remember bone remodeling has a half life of 5
years, and thus changes can be expected for at
least that time
35
Bone circulation protocol:
! Oral chelation:
!Garlic Forte 2/day
!Cayenne 2/day
!Cyruta 6/day
! Promoting osteoblastic remodeling:
!Biost 6/day
!Cataplex D 6/day
!Gotu Kola Complex 2/day
!Bone Complex 2/day
36
Review - Therapeutic Rationale
This is the reason why we do and dont do
Therefore it is the reason why the patient will do or not what
you recommend
It is the source of hope and the starting place
The functional practitioner serves from this rationale in all
endeavors, and it becomes the practice style making
incursions into disease conditions based on a rationale and
an accountable procedure
this expands the practice and builds practitioner
confidence
Have a reason for what you recommend!
Page 10
13
Sequential Intervention
! By giving hope through discussion of therapeutic rationale and then
accountably determine if the therapy had efficacy it is possible to initiate
activity that may assist a person to make the changes that result in healing
! Sequential intervention and accountable follow-up can show what has
worked and what may still need to be employed
! Sequentially detoxify the liver to promote endocrine balance
! Allow every condition to become a strategic consideration of possible
etiology and therapeutic rationale people are in search of experts reveal
yourself
! The comprehensive nature of nutritional therapy means there is always more
physiology to optimize and support leaving an individual constantly refining
as long as they wish to further improve their status
! If the practitioner is accountable s/he will be allowed to experiment with
reasonable ideas
38
Change the world
It wants to
Change the world
It wants to
Page 11
Purification & Weight Management
800-848-5061
www.standardprocess.com
L3700
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Refresh. Replenish. Rejuvenate.
Purification and Weight Management Programs
Founded in 1929 by Dr. Royal Lee,
Standard Process has been a leader in the field
of natural whole food supplements for more than 75
years. Dr. Royal Lee believed that, The quality of a
whole food supplement is dependent on the quality of
the manufacturing process. This remains the
foundation of the Standard Process doctrine today.
Owned and operated by relatives of Dr. Lee,
Standard Process manufactures its supplements from
start to finish at its facility located in the heartland of
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companys 1,000 acres of farmland and continuing
through the final stages of our unique processing,
Standard Process provides the highest
quality food supplements available.
The History & Principles Of
Standard Process
Page 12
Challenging? Of course. Rewarding? Absolutely.
What is Purification?
Purification is merely the internal cleansing and
detoxification of your body. Think of it as
spring cleaning for your insides.
It requires making new, healthier choices for yourself. You
will be discontinuing fast foods, processed convenience
foods, and sugar-laden snacks, which place an unnecessary
load on your body. Say goodbye to cheeseburgers, French
fries, salt, sugar, and dairy products. Say hello to whole,
unprocessed, preservative-free foods, lots of pure spring
water, tasty shakes, and whole food supplements.
In the process, you will learn about your body and its
needs. Youre also likely to shed some extra weight.
Rid yourself of accumulated sludge. And expel energy-
zapping wastes.
How is Purification Different
than any Other Diet?
Fad diets sell a lot of books, but they ignore the way our
bodies actually work. Gaining the weight back (plus a
little extra) is all too common.
Standard Process purification and weight management
programs are different. They are not diets. They are
programs that help you live a healthier life.
They use whole food supplements to help your body
purify and rebuild itself. Naturally. From the inside out.
Youll also be supporting all of your organ systems that
play a role in purification.
Depending upon the program you choose, you may find
yourself eating foods that may be new to you. As a result,
youll be enjoying some new tastes, new textures, and a
whole new you.*
*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Your Bodys Junk Drawer
You probably have a junk drawer at home.
It holds a mishmash of nuts and bolts, some old
keys, a pair of pliers, a night-light bulb, and a
roll of duct tape.
Your body also collects junk. This junk
comes from the food you eat, the water you
drink, and the air you breathe. It includes
pesticides, heavy metals, chemicals, caffeine,
pollution, and preservatives.
Also, simply living creates wastes. As you read
this, your body is making ammonia and carbon
dioxide. These and other poisons are created
by the workings of each cell.
Its the job of your liver, lymphatic system,
kidneys, lungs, intestines, blood, and skin to
filter these toxins from your body. When
overloaded, your body becomes inefficient.
Like a furnace with a clogged filter, it collects
toxins.
If these toxins arent eliminated, your well-
being is compromised. Have you experienced:
Weight gain
Feeling tired or fatigued
Poor digestion
Difficulty sleeping
Food cravings
Mental fog
Moodiness
Low libido
If you answered yes to any of the above,
you would likely benefit from a Standard
Process purification and weight
management program.*
Ready for a
healthier you?
Ask your health care
professional for
more details and
get started today!
Page 13
Please copy for your patients.
800-558-8740 | standardprocess.com These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
A-F Betafood
Contains Many Nutrients, Including Betaine, to Protect the Liver

and Enhance Its Function
The whole food beet ingredients in A-F Betafood contain two important
phytonutrients, betalains and betaine, to support and protect the liver. Betalains
are the pigments found in beets that are generally protective to the liver and
colon and also protect the body against oxidative stress. Betaine has been shown
in laboratory and animal studies to protect cells, proteins, and enzymes from
environmental stress and support important metabolic functions of the liver and
kidneys. A-F Betafood also contains many essential vitamins and minerals to
support overall healthy functioning of the liver and the body.

How A-F Betafood Keeps You Healthy
Promotes healthy liver function
The betaine in A-F Betafood is an effective lipotrophic agent, which promotes
the transportation and use of fats, helping to prevent the accumulation of fat in
the liver.

Maintains healthy metabolic function
The B-vitamin complex, found in nutritional yeast, is a family of vitamins that
work together to metabolize fats, carbohydrates, and proteins. Vitamin B
6

supports the metabolism of carbohydrates by facilitating glycogen breakdown.
Iodine is required to produce the two hormones in the thyroid gland responsible
for regulating the bodys rate of metabolism, reproductive functions, and growth
and development. Magnesium is needed to metabolize carbohydrates and fats
for energy, and is a cofactor for ATP metabolism. ATP is needed to produce the
energy that is required for metabolic processes throughout the body.
Provides many essential nutrients to support overall health

Calcium and magnesium are essential to bone health and several enzymatic
reactions in the body. Calcium is necessary for blood coagulation,
vasoconstriction and vasodilation, nerve impulse transmission, muscle
contraction, hormone secretion, maintenance and function of cell membranes,
and membrane permeability. Magnesium supports DNA synthesis, the synthesis
of the antioxidant enzyme glutathione, and the transport of ionizable calcium
and potassium across cell membranes.

Promotes cellular health
Beets are rich in folate, a nutrient that supports the production and maintenance
of new cells. Potassium maintains cell-membrane integrity. Vitamin A supports
healthy cellular growth and helps the body maintain healthy mucous membranes.
Vitamin B6 supports the formation and function of red blood cells. The essential
fatty acids (EFAs), like those found in axseed oil, mixed tocopherols, and soybean
lecithin, support cell structure.
A
-
F

B
e
t
a
f
o
o
d

Introduced in 1951
Content:
90 tablets
360 tablets
Suggested Use: Two tablets per meal,
or as directed.
Supplement Facts:
Serving Size: 2 tablets
Servings per Container: 45 or 180
Amount
per Serving %DV
Calories 2
Total Carbohydrate 1 g <1%*
Sugars 1 g
Vitamin A 3,000 IU 60%
Vitamin B
6
0.3 mg 15%
Iodine 40 mcg 25%
*Percent Daily Values (DV) are based on a
2,000-calorie diet.
Proprietary Blend: 546 mg
Carrot (root), beet (root), oat our, dried beet
(leaf) juice, defatted wheat (germ), calcium
lactate, magnesium citrate, bovine liver,
nutritional yeast, bovine kidney, bovine prostate,
alfalfa our, bovine orchic extract, bovine
liver-fat extract, axseed-oil extract, mixed
tocopherols (soy), and soybean lecithin.
Other Ingredients: Honey, calcium stearate,
arabic gum, starch, sucrose (beets),
vitamin A palmitate, prolamine iodine (zein),
ascorbic acid, and pyridoxine hydrochloride.
Two tablets supply approximately: 170 mg
beet-leaf juice and beet powder and 130 mg
carrot powder.
Warning: Women who are pregnant, may
become pregnant, or are lactating should
limit their intake of vitamin A (retinol) and
use vitamin A products only as directed by a
qualied health care professional. Consumption
of large amounts of vitamin A (retinol) has been
linked to serious health problems.
Sold through health care professionals.
Page 14
800-558-8740 | standardprocess.com 2008 Standard Process Inc. 2012 Standard Process Inc. ( This is a subsequent edition of the work published in 2008.) All rights reserved. T0775 1/12
A-F Betafood
What Makes A-F Betafood Unique

Product Attributes
Ingredients are derived from whole food sources
The combination of whole foods along with their vitamin complexes
promotes the healthy transport and metabolism of blood fats and supports
healthy processing of fats in the liver
The minerals and vitamins present in beets work together with other ingredients
in A-F Betafood to promote healthy liver metabolism and cellular function
Carrot root and beet root and juice provide naturally occurring antioxidants,
vitamins, and betaine
Multiple nutrients from a variety of plant and animal sources

Extracts from bovine tissues provide nutrients and support to the
corresponding tissues in humans
Vitamins, minerals, and nutrients from plants and animal tissues work
synergistically for maximum effect
Certied Organic Farming

A healthy ecosystem is created by using organic farming techniques, such as
rotating crops, fertilizing the soil with nutrient-rich cover crops and byproducts
from our processing, practicing strict weed-control standards, and continually
monitoring the health of our plants
Assures the soil is laden with minerals and nutrients
Ensures plants are nutritionally complete and free from synthetic pesticides
Manufacturing and Quality-Control Processes
Upon harvesting, nutrient-rich plants are immediately washed and
promptly processed
Preserves nutritional integrity
Low-temperature, high-vacuum drying technique
Preserves the enzymatic vitality and nutritional potential of ingredients
Not disassociated into isolated components
The nutrients in A-F Betafood are processed to remain intact, complete
nutritional compounds
Degreed microbiologists and chemists in our on-site laboratories continually
conduct bacterial and analytical tests on raw materials, product batches, and
nished products
Ensures consistent quality and safety
Vitamin and mineral analyses validate product content and specications
Assures high-quality essential nutrients are delivered
Whole Food Philosophy
Our founder, Dr. Royal Lee, challenged
common scientic beliefs by choosing a
holistic approach of providing nutrients
through whole foods. His goal was to provide
nutrients as they are found in naturein a
whole food state where he believed their
natural potency and efcacy would be
realized. Dr. Lee believed that when nutrients
remain intact and are not split from their
natural associated synergistsknown and
unknownbioactivity is markedly enhanced
over isolated nutrients. Following this
philosophy, even a small amount of a whole
food concentrate will offer enhanced
nutritional support, compared to an isolated
or fractionated vitamin. Therefore, one should
examine the source of nutrients rather than
looking at the quantities of individual
nutrients on product labels.
Studies on nutrients generally use large doses and these studies, some
of which are cited below, are the basis for much of the information we
provide you in this publication about whole food ingredients. See the
supplement facts for A-F Betafood
.
Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004
Sep;80(3):539-49.
Food and Nutrition Board Institute of Medicine. (1997). Calcium. In Dietary
Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D,
and Fluoride ( pp. 71-145). Washington D.C.: National Academy Press.
Food and Nutrition Board Institute of Medicine. (1997). Magnesium. In
Dietary Reference Intakes: Calcium, Phosphorus, Magnesium,
Vitamin D, and Fluoride (pp. 190-249). Washington D.C.: National
Academy Press.
Food and Nutrition Board, Institute of Medicine. Folic Acid. Dietary
Reference Intakes: Thiamin, Riboavin, Niacin, Vitamin B
6
, Vitamin
B
12
, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National
Academy Press; 1998:193-305.
Food and Nutrition Board, Institute of Medicine. Potassium. In Dietary
Reference Intakes for Water, Potassium, Sodium, Chloride, and
Sulfate. Washington, D. C.: National Academies Press; 2004:173-246.
Gliszczynska-Swiglo, A, Szymusiak, H, and Malinowska, P. Betanin, the main
pigment of red beet: molecular origin of its exceptionally high free radical-
scavenging activity. Food Addit Contam, 2006. 23(11): p. 1079-87.
Hetzel, B. S., Clugston, G.A. (1999). Iodine. In M. Shils, Olson, J.A., Shike,
M., Ross, A.C. (Ed.), Modern Nutrition in Health and Disease (9th ed.,
pp. 253-264). Baltimore: Williams & Wilkins.
Institute of Medicine. Dietary Reference Intakes for Energy,
Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and
Amino Acids. Washington, D. C.: National Academies Press; 2002.
Kanner, J, Harel, S, and Granit, R. Betalains--a new class of dietary
cationized antioxidants. J Agric Food Chem, 2001. 49(11): p. 5178-85.
Lee, CH, Wettasinghe, M, Bolling, BW, Ji, LL, and Parkin, KL. Betalains,
phase II enzyme-inducing components from red beetroot (Beta vulgaris
L.) extracts. Nutr Cancer, 2005. 53(1): p. 91-103.
Leklem JE. Vitamin B
6
. In: Machlin L, ed. Handbook of Vitamins. New York:
Marcel Decker Inc; 1991:341-378.
McCormick DB. Vitamin B
6
. In: Bowman BA, Russell RM, eds. Present
Knowledge in Nutrition. Vol. I. Washington, D.C.: International Life
Sciences Institute; 2006:269-277.
Peterson LN. Potassium in nutrition. In: ODell BL, Sunde RA, eds.
Handbook of nutritionally essential minerals. New York: Marcel
Dekker, Inc; 1997:153-183.
Ross AC. Vitamin A and retinoids. In: Shils M, ed. Nutrition in Health and
Disease. 9th ed. Baltimore: Williams & Wilkins; 1999:305-327.
Trumbo, P., Yates, A. A., Schlicker, S., & Poos, M. (2001). Dietary reference
intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine,
iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J Am
Diet Assoc, 101(3), 294-301.
Page 15
800-558-8740 | standardprocess.com
GF

This product contains less than 10 parts per million of gluten per serving size or less than 20 parts per million per the suggested use listed on each product label. V

Vegetarian (Lacto-ovo)
These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Choline
Helps Your Body Metabolize Fats and Support
Nervous System Function
Choline is an important vitamin-like substance that makes up a large portion
of all cell membranes and is necessary for the body to transport different fats in
the bloodstream. Choline is especially known for its ability to help keep the liver
free from fatty buildup. Choline is also a key component of two important
elements of the nervous system, acetylcholine and sphingomyelin, both
necessary for the normal functioning of the nervous system.
How Choline Keeps You Healthy

Supports healthy nervous system function
Choline and calcium are needed to transmit nerve impulses from the brain
throughout the central nervous system. Choline enhances brain function
and memory.
Keeps your heart and liver healthy

Fat is automatically transported out of the liver during the same process in
which choline becomes lecithin. The primary function of choline is to
metabolize fats throughout the body.
Maintains cellular health

Choline furnishes an essential structural component of many biological
membranes. Choline donates methyl groups that are necessary in order to
synthesize other important compounds needed for various physiological
processes.
C
h
o
l
i
n
e
Introduced in 1947
GF

V
Content:
90 tablets
Suggested Use: One tablet per meal,
or as directed.
Supplement Facts:
Serving Size: 1 tablet
Servings per Container: 90
Amount
per Serving %DV
Calories 2
Choline 175 mg
Ingredients: Choline bitartrate, honey, and
calcium stearate.
Excellent source of choline.
Page 16
Choline
What Makes Choline Unique
Product Attributes
A supplement form of choline provides consistent bioavailability
Choline levels vary considerably in food, making it difcult to determine the
amount of choline actually available for utilization by the body

nished products
Studies on nutrients generally use large doses and these studies,
some of which are cited below, are the basis for much of the
information we provide you in this publication about whole food
ingredients. See the supplement facts for Choline.
Anderson L.E. 1998. Mosbys Medical, Nursing, & Allied Health
Dictionary. 5th ed. Mosby: St. Louis. 246, 326.
Balch J.F., Balch P.A. 1997. Prescription for Nutritional Healing. 2nd
ed. Avery Publishing Group: Garden City Park. 17, 23, 55.
Berdanier C.D. 1995. Advanced Nutrition Micronutrients. CRC Press:
Boca Raton.130-133,158-172.
Blusztajn J.K., et al. Imprinting of hippocampal metabolism of choline
by its availability during gestation: implications for cholinergic
neurotransmission. Paris Journal of Physiology. Jun-Aug 1998;
92(3-4): 199-203.
Caamano J., et al. Effects of CDP-choline on cognition and cerebral
hemodynamics in patients with Alzheimers disease. Methods Find
Exp Clin Pharmacol. Apr 1994; 16(3): 211-218.
Corona GL., et al. Clincal and biochemical responses to therapy in
Alzheimers disease and multi-infarct dementia. Eur Arch Psychiatry
Neurol Sci. 1989; 239(2): 79-86.
Darvesh S., et al. Cholinesterases in cardiac ganglia and modulation of
canine intrinsic cardiac neuronal activity. Journal of the Autonomic
Nervous System. Jul 15 1998; 71(2-3): 75-84.
Denda A., et al. Inhibition by piroxicam of oxidative DNA damage, liver
cirrhosis and development of enzyme-altered nodules caused by a
choline-decient, L-amino acid-dened diet in rats. Carcinogenesis.
Oct 1997; 18(10): 1921-1930.
Denda A., et al. Prevention by inhibitors of arachidonic acid cascade of
liver carcinogenesis, cirrhosis and oxidative DNA damage caused
by a choline-decient, L-amino acid-dened diet in rats. Mutation
Research. Jun 18 1998; 402(1-2): 279-288.
Emmert J.J., et al. Hepatic betaine-homocysteine methyltransferase
acitivity in the chicken is inuenced by dietary intake of sulfur amino
acids, choline and betaine. Journal of Nutrition. Aug 1996; 126(8):
2050-2058.
Geiger J., et al. The effect increased choline levels on the synthesis and
release of acetycholine in heart atria in white rats. Bratisl Lek Listy.
Dec 1992; 93(12): 610-614.
Ghoshal A.K. New insight into the biochemical pathology of liver in choline
deciency. Critical Review of Biochemical Molecular Biology.
1995; 30(4): 263-273.
Giovannini M.G., et al. Effect of subchronic treatment with metrifonate
and tacrine on brain cholinergic function in aged F344 rats. European
Journal of Pharmacology. Jul 31 1998; 354(1): 17-24.
Hacker H.J., et al. Pyruvate kinase isoenzyme shift from L-type to M2-type
is a late event in hepatocarcinogenesis induced in rats by a choline-
decient/DL-ethionine-supplemented diet. Carcinogenesis. Jan
1998; 19(1): 99-107.
Holmes-McNary M.Q., et al. Choline and choline esters in human and rat
milk and in infant formulas. American Journal of Clinical Nutrition.
Oct 1996; 64(4): 572-56.
Kenney J.L., Carlberg K.A. The effect of choline and myo-inositol on liver
and carcass fat levels in aerobically trained rats. International Journal
of Sports Medicine. Feb 1995; 16(2): 114-116.
Kobayashi E., et al. Inhibitory effects of N,N-diphenyl-p-phenylenediamine
on the early stage of the enhanced hepatocarcinogenesis caused by
coadministration of ethionine and a choline-decient L-amino acid-
dened diet in rats. Exp Toxicol Pathol. Jun 1996; 48(4): 275-282.
Lindmar R., et al. Characterization of choline efux from the perfused
heart at rest and after muscarine receptor activation. Naunyn
Schmiedibergs Arch Pharmacol. Mar 1986; 332(3): 224-229.
Machlin L.J. 1984. Handbook of Vitamins. Marcel Dekker, Inc.: New
York. 550-561.
Mock T., et al. Effects of fatty acids on phosphatidylcholine biosynthesis
in isolated hamster heart. Biochemical Cellular Biology. May 1986;
64(5): 413-417.
Nakae D., et al. Production of both 8-hydroxydeoxyguanosine in liver DNA
and gamma-glutamyltransferase-positive hepatocellular lesions in
rats given a choline-decient, L-amino acid-dened diet. Japanese
Journal of Cancer Research. Nov 1990; 81(11): 1081-1084.
Pieri C. Chronic choline treatment improves the in vivo membrane
permeability of old hepatocytes to Rb+. Boll Soc Ital Biol Sper. Oct
1989; 65(10): 909-915.
Pitchford P. 1993. Healing with Whole Foods. North Atlantic Books:
Berkeley. 122, 177-185.
Rabkin S.W. Effect of exogenous CDP-choline on choline metabolism in
isolated adult rat ventricular myocytes under normoxic and hypoxic
conditions. Cellular Biochemical Function. Jun 1993; 11(2):
137-143.
Rabkin S.W. Effects of chlorpromazine and trifuluoperazine on choline
metabolism and phosphatidylcholine biosynthesis in cultured chick
heart cells under normoxic and anoxic conditions. Biochemical
Pharmacology. Jul 15 1989; 38(14): 2349.
Sandmann J., et al. The effects of phorbol esters on choline phospholipid
hydrolysis inheart andbrain. EuropeanJournal of Pharmacology. Mar 13
1990; 188(2-3): 89-95.
Sardesai V.M. 1998. Introduction to Clinical Nutrition. Marcel Dekker,
Inc.: New York. 79-84, 233-235.
Scheider W.L. 1983. Nutrition, Basic Concepts and Applications.
McGraw-Hill Book Company: New York. 202-203, 222-224.
Sesca E., et al. Choline feeding depresses the phospholipase C activity in
the regenerating liver of female rats. Boll Soc Ital Biol Sper. Nov-Dec
1996; 72(11-12): 325-329.
Sesca E., et al. The delay in rat liver regeneration by choline is associated
to alteration in C-myc expression. Boll Soc Ital BiolSper. Jul-Aug
1996; 72(7-8): 217-222.
Sheard N.F., et al. Plasma choline concentration in humans fed
parenterally. American Journal of Clinical Nutrition. Feb 1986;
43(2): 219-224.
Sheard N.F., Zeisel S.H. Choline: an essential dietary nutrient? Nutrition.
Jan-Feb 1989; 5(1): 1-5.
Shils M.E., Young V.R. 1988. Modern Nutrition in Health and Disease.
7th ed. Lea & Febiger: Philadelphia. 142-154, 440-449.
Shinozuka H., et al. Choline deciency and chemical carcinogenesis. Adv
Exp Med Biol. 1986; 206, 253-267.
Sugiyama T., et al. Enhancing effect of a choline-decient diet on
alterations of hepatic drug-matabolizing enzymes ini hepatitis- and
hepatoma-predisposed rats (LEC rats). Japanese Journal of Cancer
Research. Apr 1991; 82(4): 390-396.
Tamura K., et al. Inhibition by N-(4-hydroxyphenyl) retinamide and
all-trans-retinoic acid of exogenous and endogenous development
of putative preneoplastic, glutathione S-transferase placental form-
positive lesions in the livers of rats. Carcinogenesis. Nov 1997;
18(11): 2133-2141.
Tsujiuchi T. Increased telomerase activity in hyperplastic nodules and
hepatocellular carcinomas induced by a choline-decient L-amino
acid-dened diet in rats. Japanese Journal of Cancer Research.
Nov 1996; 87(11): 1111-1115.
Tver D.F., Percy R. 1989. The Nutrition and Health Encyclopedia. 2nd
ed. Van Nostrand Reinhold: New York. 117-118, 86-88, 266.
Unelius L., et al. Choline+ is a low-afnity ligand for alpha
1-adrenoceptors. Journal of Biochemical Pharmacology. Oct 7
1994; 48(7): 1519-1523.
West Suitor C.J., Crowley F., Merrily R.N. 1984. Nutrition, Principles and
Application in Health Promotion. 2nd ed. J.B. Lippincott Company:
Philadelphia. 49, 65-66.
Wilson E.D., Fisher K.H., Fuqua M.E. 1965. Principles of Nutrition. 2nd
ed. John Wiley & Sons: New York. 136-150, 308-309.
Yokota K., et al. Effects of a choline-decient diet and a hypolipidemic
agent on single glutathione S-transferase placental form-positive
hepatocytes in rat liver. Japanese Journal of Cancer Research. Feb
1990; 81(2): 129-134.
1999 Standard Process Inc. 2012 Standard Process Inc. ( This is a subsequent edition of the work published in 1999.) All rights reserved. T2565 1/12
Page 17
Betacol
Promotes Healthy Liver, Cardiovascular, and Cellular Function

Betacol contains Tillandsia usneoides, a source of important phytochemicals that
contribute to cardiovascular and cellular health. Several bioactive compounds,
including vitamin C, carotene, and 3-hydroxy-3-methylglutaric acid (HMG), are
found in Tillandsia usneoides. Vitamins, minerals, and phytochemicals in Betacol
work at the cellular level to maintain healthy blood glucose and cholesterol levels
in individuals with normal levels. Betaine in Betacol is important for healthy
liver function, especially the metabolism of fat.
How Betacol Keeps You Healthy

Promotes healthy liver function
Betaine is a lipotrophic agent that promotes transportation and metabolism of
fats, helping to prevent the accumulation of fat in the liver. Several studies
demonstrate betaines unique ability to support a healthy liver.
Supports cardiovascular health

Tillandsia usneoides supports arterial health by helping to maintain normal
serum cholesterol levels in individuals with normal levels. HMG, the bioactive
compound in Tillandsia usneoides, has been shown in several studies to help
support cardiovascular health factors. Several studies have conrmed that HMG
operates at the enzymatic level in the kidney and intestine. Studies also indicate
that HMG may help maintain healthy cardiovascular function. Betacol contains
vitamin B
6
, which is important for red-blood-cell formation and helps maintain
optimum homocysteine levels in the blood. Vitamin B
6
is well documented for
its ability to support the heart muscle and associated blood vessels.
Promotes healthy cellular function

Vitamin B
6
is required to synthesize the nucleic acids RNA and DNAthe
molecules that carry the genetic instructions for normal cellular growth and
reproduction. Betacol also contains niacin, which functions as a coenzyme that is
key to cellular respiration, carbohydrate and protein metabolism, and lipid
synthesis. Niacin is a hydrogen acceptor, combining with hydrogen atoms as they
are removed from the food we eat. Once this occurs, the coenzyme continues
transferring these atoms to other compounds in a series of complex oxidation
reactions. Several studies indicate that extracts from Tillandsia usneoides contain
compounds capable of reducing serum glucose. HMG may also help support
liver function.
B
e
t
a
c
o
l

Introduced in 1946
Content:
40 capsules
Suggested Use: One capsule per meal,
or as directed.
Supplement Facts:
Serving Size: 1 capsule
Amount
per Serving %DV
Calories 2
Niacin 10 mg 50%
Vitamin B
6
2 mg 100 %
Tillandsia usneoides, soy (bean), bovine liver
PMG extract, betaine hydrochloride, calcium
lactate, defatted wheat (germ), potassium
bicarbonate, choline bitartrate, inositol,
disodium phosphate, bovine adrenal Cytosol
extract, oat our, and ascorbic acid.
Other Ingredients: Gelatin, water, niacinamide,
pyridoxine hydrochloride, colors, and calcium
stearate.
Page 18
Betacol
What Makes Betacol Unique

Product Attributes
A distinctive product that contains choline
Choline is essential to metabolize fat cholesterol, proteins, and carbohydrates
effectively
Multiple nutrients from a variety of plant and animal sources

Extracts from bovine tissues provide nutrients and support to the
corresponding tissues in humans
Contains Protomorphogen
extracts
Standard Process uses a unique manufacturing method of deriving tissue cell
determinants from animal glands and organs
Help provide cellular support and rehabilitation to the corresponding human
tissues
Important antigenic properties of nucleoprotein-mineral determinants are the
foundation of the product

nished products
supplement facts for Betacol
.
Dictionary. 5th ed. St. Louis, MO: Mosby: 1366.
Arny N.P. Spanish Moss and Ball Moss. University of Florida: Cooperative
Extension Service Institute of Food and Agricultural Sciences. Online.
21 May 2000.
Balch J.F., Balch Phyllis A. 1997. Prescription for Nutritional Healing. 2nd
ed. Garden City Park, NY: Avery Publishing Group: 15-16.
Berdanier C.D. 1995. Advanced Nutrition Micronutrients. Boca Raton,
FL: CRC Press: 94-105.
Coffee C.J. 1998. Metabolis. 1st ed. Madison, CT: Fence Creek
Publishing: 69.
Costa M., Di Stasi L.C., Kirizawa M., et al. 1989. Screening in mice of some
medicinal plants used for analgesic purposes in the state of Sao Paulo,
part II. J Ethnopharmacol. 27(1-2): 25-33.
Di Padova C., Bosisio E., Cighetti G., et al. 1982. 3-Hydroxy-3-methylglutaric
acid (HMGA) reduces dietary cholesterol induction of saturated bile in
hamster. Life Sci. 30(22): 1907-1914.
Duke J. USDA ARS NGRL. Phytochemical and Ethnobotanical Database.
Beltsville, MD: Beltsville Agricultural Research Center. Online. 22
May 2000.
Guyton A.C., Hall J.E. 1997. Human Physiology and Mechanisms of
Disease. 6th ed. Philadelphia, PA: W.B. Saunders Company: 589.
Kirschmann J.D. 1979. Nutrition Almanac. Revised ed. New York, NY:
McGraw-Hill Book Company: 25-27.
Labate M.E., Dam R. 1980. Effect of 3-hydroxy-3-methylglutaric acid on
cholesterol metabolism in female Japanese quail. Poult Sci 59(2):
383-389.
Lupien P.J., Moorjani S., Brun D., et al. 1979. Effects of 3-hydroxy-3-
methylglutaric acid on plasma and low-density lipoprotein cholesterol
levels in familial hypercholesterolemia. J Clin Pharmacol. 19(2-3):
120-126.
Moorjani S., Lupien P.J. 1977. Effect in vitro of 3-hydroxy-3-methylglutaric
acid on the synthesis of mevalonate and its precursors. Arch Int Physiol
Biochim 85(1): 1-10.
Murakami T., Nagamura Y., Hirano K. 1998. The recovering effect of betaine
on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol
44(2): 249-255.
Pitchford P. 1993. Healing With Whole Foods. Revised ed. Berkeley, CA:
North Atlantic Books: 122, 402-403.
Savoie L.L., Lupien P.J. 1975. Organ distribution of 3-hydroxy-3-
methylglutaric acid, a potential anticholesterolemic agent. Can J Physiol
Pharmacol 53(4): 638-643.
Savoie L.L., Lupien P.J. 1975. Preliminary toxicological investigations of
3-hydroxy-3-methylglutaric acid (HMG). I: Study of acute toxicity and
of teratogenic activity in rats and mice. Arzneimittelforschung 25(8):
1284-1286.
7th ed. Philadelphia, PA: Lea and Febiger: 370-381.
Tillandsia usenoides. Ecology and Evolutionary Biology Conservatory.
Online. 17 May 2000.
Tver D.F., Russell P. 1989. The Nutrition and Health Encyclopedia. 2nd
ed. New York, NY: Van Nostrand Reinhold: 366-368, 445-446.
Van Niekerk J.L., Hendriks T., Gevers-Leuven, J.A., et al. 1984. The lipid-
lowering effects of 3-hydroxy-3-methylglutaric acid and bile acid drainage
in WHHL rabbits. Clin Sci 67(4): 439-444.
Wilson E.D., Fisher K.H., Fuqua M.E. 1965. Principles of Nutrition. 2nd ed.
New York, NY: John Wiley & Sons, Inc: 290-294.
Witherup K.M., McLaughlin J.L., Judd R.L., et al. 1995.
Identication of 3-hydroxy-3-methylglutaric acid ( HMG) as a
hypoglycemic principle of Spanish moss (Tillandsia usneoides).
J Nat Prod 58( 8): 1285-1290.
Yousufzai S.Y., Siddiqi M. 1976. 3-Hydroxy-3-methylglutaric acid and triton-
induced hyperlipidemia in rats. Experientia 32(9): 1178-1179.
Yousufzai S.Y., Siddiqi M. 1977. Serum and liver lipid responses to
3-hydroxy-3-methylglutaric acid in rats on different carbohydrate diets.
Lipids 12(3): 262-266.
Page 19
Introduced in 1969
Content:
90 capsules
or as directed.
Supplement Facts:
Amount
per Serving %DV
Calories 3
Niacin 2.8 mg 15%
Vitamin B
6
0.8 mg 40%
Iron 2.7 mg 15%
Iodine 9.6 mcg 6%
Zinc 5.5 mg 35%
Copper 109 mcg 6%
Bovine liver PMG
extract, Spanish black

radish (root), bovine liver, calcium lactate,
carrot (root), Tillandsia usneoides, beet (root),
dried beet (leaf) juice, oat our, betaine
hydrochloride, magnesium citrate, choline
bitartrate, soy (bean), potassium bicarbonate,
bovine kidney, bovine prostate, bovine adrenal
Cytosol
extract, defatted wheat (germ),

bovine liver fat extract, bovine orchic extract,
ascorbic acid, axseed oil extract, and mixed
tocopherols (soy).
Other Ingredients: Gelatin, zinc liver chelate,
iron liver chelate, water, calcium stearate,
niacinamide, copper liver chelate, colors,
pyridoxine hydrochloride, arabic gum, starch,
sucrose (beets), vitamin A palmitate, and
prolamine iodine (zein).
Warning: Accidental overdose of iron-
containing products is a leading cause of
fatal poisoning in children under 6. Keep this
product out of reach of children. In case of
accidental overdose, call a doctor or poison
control center immediately.
Livaplex
A Multi Food-Based Formula for the Liver

The liver is the bodys largest organ and performs more than 500 different
functions including the synthesis and utilization of carbohydrates, fats, and
proteins, the metabolism and excretion of toxins from the body, and the storage
of glycogen and several other nutrients. Livaplex is a special formula comprised
of several Standard Process ingredients designed to support the liver. This
product encourages healthy bile production and ow, the breakdown of fats,
liver-detoxication support, and the improvement of blood ow through the
liver. In addition, zinc, copper, and iron enhance the ability of the liver to
function normally.
How Livaplex Keeps You Healthy

Provides several essential vitamins and minerals to support cellular health and
metabolism of macronutrients
Vitamin A supports healthy cellular growth and helps the body maintain healthy
mucous membranes. At the cellular level, zinc supports DNA synthesis, cell
signaling, and supports protein and cell structure and function. Zinc also plays a
role in releasing hormones and supporting nerve impulse transmission. Copper
is involved in producing cellular energy, supporting the bodys natural
antioxidant functions, and aiding in iron metabolism. Iron is required for
oxygen transport and storage, energy metabolism, and many nutrient
interactions. The B vitamins are important building blocks for many metabolic
processes throughout the body. Vitamin B6 supports the metabolism of
carbohydrates through its facilitation of glycogen breakdown and niacin aids
in carbohydrate, protein, and lipid synthesis. B6 is also important for the
formation and function of red blood cells. Iodine is a trace mineral required for
thyroid-hormone synthesis.
Supports the livers natural antioxidant functions

The liver is essential in eliminating toxins from the body. Cruciferous vegetables,
like Spanish black radish, contain phytochemicals that stimulate enzymatic
activity required to support liver detoxication.

Supports digestive function
Betaine hydrochloride provides a supplemental source of hydrochloric acid
(HCl), an acid found in the gastric juice of the stomach, to help breakdown food
during digestion.
L
i
v
a
p
l
e
x
Page 20
provide you in this publication about whole food ingredients.
See the supplement facts for Livaplex
.
Bender, DA. Novel functions of vitamin B
6
. Proc Nutr Soc, 1994. 53(3):
p. 625-30.
Cervantes-Laurean D, McElvaney NG, Moss J. Niacin. In: Shils M, Olson JA,
Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th
ed. Baltimore: Williams & Wilkins; 1999:401-411.
Cousins, R. J. (2006). Zinc. In B. A. Bowman, Russell, R.M. (Ed.), Present
Knowledge in Nutrition (9th ed., Vol. 1, pp. 445-457). Washington
D.C.: ILSI Press.
Dakshinamurti, S, Dakshinamurti, K., Vitamin B
6
, in Handbook of Vitamins,
J. Zempleni, Rucker, R.B., McCormick, D.B., Suttie, J.W., Editor. 2007,
CRC Press (Taylor & Francis Group): New York. p. 315-359.
Dunn, J. T. (1998). Whats happening to our iodine? J Clin Endocrinol
Metab, 83(10), 3398-3400.
Hanlon, P. R., Webber, D. M., & Barnes, D. M. (2007). Aqueous extract
from Spanish black radish (Raphanus sativus L. var. niger) induces
detoxication enzymes in the HepG2 human hepatoma cell line. J Agric
Food Chem, 55(16), 6439-6446.
Harris, E. D. (1997). Copper. In B. L. ODell, Sunde, R.A. (Ed.), Handbook
of nutritionally essential minerals (pp. 231-273). New York: Marcel
Dekker, Inc.
Hetzel, B. S., Clugston, G.A. (1999). Iodine. In M. Shils, Olson, J.A., Shike,
M., Ross, A.C. (Ed.), Modern Nutrition in Health and Disease (9th ed.,
pp. 253-264). Baltimore: Williams & Wilkins.
Jacob R, Swenseid M. Niacin. In: Ziegler EE, Filer LJ, eds. Present
Knowledge in Nutrition. 7th ed. Washington D.C: ILSI Press;
1996:185-190.
Leklem, JE, Vitamin B
6
, in Handbook of Vitamins, L. Machlin, Editor. 1991,
Marcel Decker Inc: New York. p. 341-378.
Lugasi, A., Blazovics, A., Hagymasi, K., Kocsis, I., & Kery, A. (2005).
Antioxidant effect of squeezed juice from black radish (Raphanus
sativus L. var niger) in alimentary hyperlipidaemia in rats. Phytother
Res, 19(7), 587-591.
Mackey, AD, Davis, S.R., Gregory, J.F., Vitamin B
6
, in Modern Nutrition in
Health and Disease, M.E. Shils, Shike, M., Ross, A.C., Caballero, B.,
Cousins, R.J., Editor. 2006, Lippincott Williams & Wilkins: Philadelphia.
p. 452-461.
McCormick, DB, Vitamin B
6
, in Present Knowledge in Nutrition, B.A.
Bowman, Russell, R.M., Editor. 2006, International Life Sciences
Institute: Washington, D.C. p. 269-277.
Trumbo, P., Yates, A. A., Schlicker, S., & Poos, M. (2001). Dietary reference
intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine,
iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J Am
Diet Assoc, 101(3), 294-301.
Turnlund, J. R. (2006). Copper. In M. E. Shils, Shike, M., Ross, A.C.,
Caballero, B., Cousins, R.J. (Ed.), Modern Nutrition in Health and
Disease (10th ed., pp. 289-299). Philadelphia: Lippincott Williams
& Wilkins.
Uauy, R., Olivares, M., & Gonzalez, M. (1998). Essentiality of copper in
humans. Am J Clin Nutr, 67(5 Suppl), 952S-959S.
Yip, R., Dallman, P.R. . (1996). Iron. In E. E. Ziegler, Filer, L.J. (Ed.), Present
Knowledge in Nutrition (7th ed., pp. 277-292). Washington D.C.:
ILSI Press.
Livaplex
What Makes Livaplex Unique

Product Attributes
Multiple nutrients and minerals from a variety of plant and animal sources
Extracts from bovine tissues provide cellular support and rehabilitation
to the corresponding tissues in humans
extracts
Standard Process uses a unique manufacturing method of deriving tissue
cell determinants from animal glands and organs

promptly processed
The nutrients in Livaplex are processed to remain intact, complete
nished products
Page 21
Passion Flower (Passiora incarnata)
A Phytotherapists Passion
Philosopher and teacher Rudolf Steiner once
said that, for every human illness, somewhere
in the world there exists a plant which is the
cure. I believe that there is a healing potential
locked inside plants which is integral with their
evolution, just as it is part of human evolution to
learn to tap this wonderful gift of Nature.
Associate Professor Kerry Bone
MediHerb Co-Founder and
Director of Research and Development
Quality is our Passion
* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
LivCo
LivCo
is a unique combination of Schisandra berries, concentrated Milk

Thistle seed and Rosemary leaf. Schisandra berries have been used as
a tonic in traditional Chinese medicine.
1
Clinical trials suggest that to
be effective Milk Thistle products should contain substantial levels of
the important plant constituents: avanolignans (collectively known as
silymarin). The main avanolignans are silybin, silychristin and silydianin.
In these trials, concentrated Milk Thistle seed extract was used to support
liver function.
2
*
How LivCo
Keeps You Healthy

Aids in the elimination of toxins and cleanses the liver
Milk Thistle has been used traditionally to aid in the elimination of toxins
and cleanse the liver.
3
*
One of the things that helps Milk Thistle achieve this is due to whats
called enterohepatic circulation the circulation that occurs between the
intestine and the liver:
3,4
after the avanolignans in Milk Thistle are swallowed they are
absorbed in the intestine
then excreted from the liver in the bile
and then they are reabsorbed in the intestine*
This means that the cells of the liver are in contact with the
avanolignans at a higher concentration than the level reached in the
bloodstream.
3,4
It is the contact at the cellular level of the liver that is
important (see next).*
Protects liver tissue
Milk Thistle and Schisandra help protect liver tissue.
1,5
Constituents of
Schisandra known as lignans are likely to be important for this activity.
Schisandra lignans may do this by enhancing the normal production of
the antioxidant glutathione in the liver.
1
* (See over page Antioxidant
Protection.)
The avanolignans of Milk Thistle help to ensure the integrity of the liver
cell:
from the damaging effects of excessive free radicals
5,6

by eliminating toxins
5
*
The avanolignans of Milk Thistle also provide support by increasing the
normal rate of synthesis of structural and functional proteins in liver cells.
This helps the livers normal repair process.
5
This increase in the normal
synthesis of proteins is also one of the ways Schisandra helps protect liver
tissue.
1
*
Supplement Facts
Serving size: 1 tablet
Servings per container: 40, 120
Amount per Serving %DV
Calories 2
Calcium 97 mg 9%
Schisandra fruit 6:1 extract 167 mg

from Schisandra chinensis fruit 1.0 g
Rosemary leaf 5:1 extract 100 mg

from Rosmarinus ofcinalis leaf 500 mg
Milk Thistle seed 70:1 extract 30 mg

from Silybum marianum seed 2.1 g
Containing avanolignans
calc. as silybin 24 mg
Daily Value (DV) not established.

Other ingredients: Calcium acid phosphate, cellulose, maltodextrin, sodium
starch glycollate, hypromellose, sorbitol and magnesium stearate.
Caution: Contraindicated in pregnancy. Contraindicated during lactation unless
otherwise directed by a qualied health care professional. In anemia and
cases where iron supplementation is required, do not take simultaneously
with meals or iron supplements.
Product No Content
M1360 40 Tablets
M1365 120 Tablets
LivCo
M1360 / M1365
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MediHerb products are developed
by experts and leaders in the eld of
herbal therapy, using scientic evidence
and hundreds of years of traditional
knowledge.
Kerry Bone and over 20 health care
professionals work within MediHerb
while still managing their own
clinical practices, plus we consult
with an advisory board of health care
professionals from around the world.
Our products are made using only
the highest quality ingredients which
are extensively tested for purity and
potency. The MediHerb manufacturing
plant operates to a strictly regulated
pharmaceutical standard and is regularly
audited by the Therapeutic Goods
Administration (similar to the FDA), the
same body that audits conventional
pharmaceutical manufacturing facilities.
The comprehensive regulations in
Australia mean that you receive a
safe and effective product that has
been manufactured to pharmaceutical
standards.
We know from our experience as health
care professionals that the quality
of a product you take makes a huge
difference to the health outcome you
experience. We dedicate ourselves
to researching and making the best
possible products to deliver health
solutions that work.
Exclusive United States Distributor for MediHerb
800-558-8740 www.standardprocess.com
www.mediherb.com
Supports healthy liver function and digestive health
Rosemary leaf has been used traditionally to support healthy liver function and when the
digestion requires support.
7
*
Provides antioxidant protection
Antioxidants help protect cells from the damaging effects of excessive free radicals. Free radicals
are highly reactive substances created in the body that may affect cells.*
As well as protecting liver cells directly from the damaging effects of excessive free radicals, the
avanolignans of Milk Thistle may also provide broader antioxidant protection. They may do this
by enhancing the normal production of some of the bodys antioxidants: superoxide dismutase
and the glutathione system.
1
This means that the avanolignans may provide antioxidant
protection for other body tissues as well as the liver.*
What Makes LivCo
Unique
LivCo
is unique in the professional herbal products industry because:

It is a liver support product that also provides antioxidant protection
The label states exactly how much each tablet contains of the important plant constituents
(avanolignans)
MediHerb tests the quantity of avanolignans in Milk Thistle raw material
Unique Manufacture & Analytical Testing
Quality and safety ensured
Manufactured in Australia to the high standards of international pharmaceutical Good
Manufacturing Practice
Raw materials and nished product are subjected to tough quality standards, including use
of the latest and most relevant chemical analysis methods
References
1
American Herbal Pharmacopoeia. Schisandra Berry Schisandra chinensis: Analytical, Quality Control, and Therapeutic Monograph. American
Herbal Pharmacopoeia, Santa Cruz, October 1999.
2
Blumenthal M, Brinckmann J, Wollschlaeger B. The ABC Clinical Guide to Herbs. American Botanical Council, Austin, Texas, 2003.
3
Rainone F. Am Fam Physician 2005; 72(7): 1285-1288
4
Faulstich H, Jahn W, Wieland T. Arzneim Forsch 1980; 30(3): 452-454
5
Wellington K, Jarvis B. BioDrugs 2001; 15(7): 465-489
6
Fraschini F, Demartini G, Esposti D. Clin Drug Invest 2002; 22(1): 51-65
7
ESCOP Monographs: The Scientic Foundation for Herbal Medicinal Products, 2nd Edn. ESCOP, European Scientic Cooperative on Phytotherapy,
Exeter, 2003.
TM1360 05/11 MediHerb
2011. All rights reserved.

Page 23
Livton
Complex: Sustainable Liver Toning

Livton
Complex is a unique combination of concentrated Milk Thistle

seed extract, Globe Artichoke leaf, Dandelion root, Bupleurum root and
Fringe Tree stem bark.*
The importance of the liver
A poorly functioning liver can have a wide-ranging effect on health
eg sluggish digestion, constipation and digestive issues such as food
intolerances. The liver is actively involved in the processing of what we
ingest (take into our body). It also has to deal with any pollutants that we
are exposed to. Alcohol, drug medications (eg painkillers, contraceptive
pill) and a diet high in fat may put the liver under stress.
1
*
Closely associated with the liver is the gallbladder. The liver makes bile
which is stored in the gallbladder. Bile plays an important role in fat
digestion and absorption. It also helps with excretion of several important
waste products from the blood.
2
*
What is a liver tonic?
A tonic is popularly thought of as something that makes you feel better,
stronger or healthier. Natural clinicians use liver tonics to improve the
tone, vigor and function of the liver.
3
Improving the tone assists with the
proper functioning of the liver tissues providing healthy responses when
challenged.*
Spring tonics have been used for centuries and were often based
upon liver herbs, to ensure that, after a winter of unhealthy food the
liver would be strengthened. They helped in cleansing and refreshing
the whole body. Because the modern diet is often less than ideal a
spring tonic is useful at any time of the year.
4
Spring or liver tonics are
recommended when the liver is under stress or not functioning well.
3
*
Why use herbal products from an environmentally-responsible
manufacturer?
Herbal products are made from living plants. It is very important
that as consumers and manufacturers we do all we can to ensure
the continuation of these important plant species. Many species
are threatened by destruction of their habitat and by unsustainable
harvesting. One plant under threat is Fringe Tree (Chionanthus virginica)
which is native to the United States. It is a large shrub or small tree that
can grow to about 20 feet (6 m) and has showy, creamy white owers.
The bark of the root has been used therapeutically. But harvest of the root
bark often results in death of the tree.*
One strategy to solve destructive harvesting is use a different part of the
plant (eg leaves, twigs or stem) instead of the underground parts. But it
is necessary to evaluate the differences and similarities between various
parts of the same plant with respect to chemical composition. This is
called a phytochemical comparison.
5
*

Supplement Facts
Servings per container: 40, 120
Calories 2
Calcium 40 mg 4%
Globe Artichoke leaf 4:1 extract 200 mg

from Cynara scolymus leaf 800 mg
Dandelion root 4:1 extract 100 mg

from Taraxacum ofcinale root 400 mg
Milk Thistle fruit 70:1 extract 100 mg

from Silybum marianum fruit 7.0 g
Containing avanolignans calculated as
silybin 80 mg
Bupleurum root 4.5:1 extract 66.7 mg

from Bupleurum falcatum root 300 mg
Fringe Tree stem bark 5:1 extract 32 mg

from Chionanthus virginica stem bark 160 mg

Other ingredients: Calcium acid phosphate, cellulose, hypromellose,
magnesium stearate, silica and sodium starch glycollate.
Caution: Contraindicated in pregnancy. Contraindicated during lactation unless
otherwise directed by a qualied health care professional. Contraindicated in
closure of the gallbladder. In anemia and cases where iron supplementation
is required, do not take simultaneously with meals or iron supplements. Use
only with professional supervision in gallstones.
Product No Content
M1372 40 Tablets
M1378 120 Tablets
Livton
Complex
M1372 / M1378
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Page 24
knowledge.
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www.mediherb.com
MediHerbs Research & Development team conducted a phytochemical comparison and found
that there would be no loss of quality in switching from the root bark to the stem bark.
6
In
addition to this proactive example, MediHerb also has an active company policy regarding
endangered and threatened medicinal plants.*
How Livton
Complex Keeps You Healthy

Supports healthy liver and gallbladder function
Dandelion root, Globe Artichoke, Milk Thistle seed and Bupleurum are traditional liver tonics.
1,7

These herbs and Fringe Tree root bark have been used traditionally to support healthy liver and
gallbladder function.
1,3,8
A review of controlled clinical trials found that concentrated Milk Thistle
seed extract may support liver function by helping ensure the integrity of the liver cell.
9
*
Encourage healthy digestive function and assimilation
Many herbs that are used to support liver function also encourage healthy digestive function.
1

One of the main reasons is that all these herbs, except Bupleurum, assist the normal ow of bile
from the liver and/or the gallbladder.
1,3
An uncontrolled trial found that Globe Artichoke extract helped in those with mild digestive
problems. Signicant improvement was found after 2 months compared to before treatment for:
10
inability to nish a regular meal
fullness after eating or slow digestion
What Makes MediHerb Livton
Complex Unique
Livton
Complex from MediHerb is unique in the professional herbal products industry because:
It states on the label exactly how much each tablet contains of the important plant
constituents (avanolignans)
Top quality and sustainably wildcrafted Dandelion root and Fringe Tree stem bark are used in
the manufacture of this tablet
MediHerb tests the quantity of avanolignans in Milk Thistle raw material, and ensures the
avanolignans are retained in the product throughout manufacture
MediHerb developed an accurate chemical analysis to assess the true level of avanolignans
It contains Fringe Tree stem bark to help ensure continuity of supply and sustainable
environmental practice
Unique extraction method using cold percolation for the Dandelion root, Bupleurum and
Fringe Tree components of this tablet (this protects the delicate plant constituents, ensuring
a full range of constituents)
Raw materials and nished product are subjected to tough quality standards, including use
References
1
Mills S, Bone K. Principles and Practice of Phytotherapy: Modern Herbal Medicine. Churchill Livingstone, Edinburgh, 2000.
2
Guyton AC, Hall JE. Textbook of Medical Physiology, 10th Edn. W.B. Saunders, Philadelphia, 2000.
3
Bone K. Clinical Guide to Blending Liquid Herbs. Herbal Formulations for the Individual Patient. Churchill Livingstone, USA, 2003.
5
Hoffmann D. The Complete Illustrated Holistic Herbal: A Safe and Practical Guide to Making and Using Herbal Remedies. Element Books,
Rockport 1996.
5
Zschocke S, Rabe T, Taylor JL et al. J Ethnopharmacol 2000; 71 (1-2): 281-292
5
Penman KG, Bone KM, Lehmann RP. Information on le. MediHerb Research Laboratories, 3/85 Brandl Street, Eight Mile Plains, Brisbane,
Queensland, 4113, Australia, 2006.
7
World Health Organization. Medicinal Plants in the Republic of Korea. WHO Regional Ofce for the Western Pacic, Manilla, 1998.
8
Huang KC. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, 1993.
9
Crocenzi FA, Roma MG. Curr Med Chem 2006; 13 (9): 1055-1074
9
Marakis G, Walker AF, Middleton RW et al. Phytomedicine 2002; 9 (8): 694-699

Page 25
Albizia Complex: Seasonal Stress Relief
Albizia Complex is a unique combination of Albizia bark, Chinese Skullcap
root and Feverfew leaf and stem to maintain normal upper respiratory
tract and skin function.*
Albizia lebbek grows naturally in many parts of the world especially
India, parts of the Himalayas and Burma. It is also cultivated and used
for its timber and as a fodder plant.
1
The bark has been used traditionally
in India for centuries.
2
Chinese Skullcap (botanical name Scutellaria
baicalensis) has been used traditionally for centuries in China for a wide
range of applications.
3
*
Feverfew was rst used in ancient Greece and was much favored by the
Renaissance herbalists. It is said that Feverfew received the botanical
species name parthenium because the herb was used in saving the
life of a man who fell from the Parthenon (the main temple on the
Acropolis at Athens), when it was being built between 447 and 432 BC.
4,5

Contemporary interest in Feverfew arose from the British public who
used it in the late 1970s which was reported in newspapers.
6
Studies
conducted in the late 1990s revealed that top quality Feverfew extracts
should contain substantial levels of the important plant constituent
parthenolide.
7
*
How Albizia Complex Keeps You Healthy
Assists in maintaining healthy breathing passages
Albizia has been used traditionally to support healthy nasal and bronchial
passages to support free and clear breathing.
2,8
Chinese Skullcap and
Feverfew have been used traditionally to support healthy breathing.
9,10
*
Maintains normal upper respiratory tract and skin function
Chinese Skullcap is one of the most widely used Chinese herbs to support
health in the upper respiratory tract.
11,12
Albizia has been used traditionally
to promote healthy skin.
2,13
*
Promotes a normal response to occasional seasonal stresses
Anecdotal reports in the 1980s indicate that Feverfew provided support
for the upper respiratory tract during occasional seasonal stresses.
14
By
supporting healthy nasal and bronchial passages Albizia promotes a
normal response to occasional seasonal stresses.*
Support a normal immune response
The results of a controlled clinical trial suggest that Albizia supports the
body in producing a healthy prole of white blood cells when under
stress.
15
*
Supplement Facts
Servings per container: 40
Calories 2
Calcium 40 mg 4%
Chinese Skullcap root 4:1 extract 200 mg

from Scutellaria baicalensis root 800 mg
Albizia bark 8:1 extract 100 mg

from Albizia lebbek bark 800 mg
Feverfew leaf & stem 5:1 extract 10 mg

from Tanacetum parthenium
leaf & stem 50 mg

Other ingredients: Calcium acid phosphate, cellulose, sodium starch glycollate,
silica, hypromellose and magnesium stearate.
Caution: Contraindicated in individuals with known hypersensitivity to
feverfew, parthenolide or other members of the daisy family. Not to be used
during pregnancy and lactation unless otherwise directed by a qualied health
care professional.
Product No Content
M1100 40 Tablets
Albizia Complex
M1100
A
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www.mediherb.com
What Makes Albizia Complex Unique
Albizia Complex is unique in the professional herbal products industry because:
MediHerb tests raw materials for the quantity of:

parthenolide in Feverfew

MediHerb tests the quantity of parthenolide in Feverfew raw material

MediHerb conducts extensive testing to ensure the correct species of Scutellaria is used
for Chinese Skullcap raw material

Raw materials and nished product are subjected to tough quality standards

Unique extraction method using cold percolation for the Albizia and Chinese Skullcap
components of this tablet (this protects the delicate plant constituents, ensuring a full range
of constituents)
References
1
Prinsen JH. Trop Grasslands 1986; 20(2): 7883
2
Tripathi RM, Sen PC, Das PK. J Ethnopharmacol 1979; 1(4): 385-396
3
Bensky D, Clavey S, Stoger E. Chinese Herbal Medicine: Materia Medica, 3rd Edn. Eastland Press, Seattle, 2004.
4
Barker J. The Medicinal Flora of Britain and Northwestern Europe: A Field Guide including plants commonly cultivated in the region. Winter
Press, West Wickham, 2001.
5
Le Strange R. A History of Herbal Plants. Angus & Robertson, London, 1977.
6
Johnson ES. Feverfew (Overcoming common problems). London, Sheldon Press, 1984.
7
McKenna DJ, Jones K, Hughes K et al. Botanical Medicines: The Desk Reference for Major Herbal Supplements, 2nd Edn. New York, Haworth
Herbal Press, 2002.
8
Tripathi RM, Biswas M, Das PK. J Res Indian Med Yoga Homoeopath 1977; 12(3): 37-41
9
Chang HM, But PP. Pharmacology and Applications of Chinese Materia Medica. World Scientic, Singapore, 1987.
10
Grieve M. A Modern Herbal. First published 1931, reprinted Dover Publications, New York, 1971.
11
Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Springer-Verlag, Berlin, 1992.
12
Huang KC. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, 1993.
13
Kapoor LD. CRC Handbook of Ayurvedic Medicinal Plants. CRC Press, Boca Raton, 1990.
14
Britt J, Keen L. Feverfew. London, Century, 1987.
15
Mukhopadhyay B, Nagaraju K, Sharma KR. J Res Edu Indian Med 1992; 11: 17-23

Page 27
Wormwood Complex
Wormwood Complex is a unique combination of Wormwood herb, Black
Walnut green hulls, Stemona root and Clove Bud essential oil.*
The importance of healthy intestinal ora
Not all bacteria are bad, in fact some bacteria are necessary for our
survival and live in our intestine.
1
The human gastrointestinal tract (mainly
the lower end known as the colon or large bowel) is the natural habitat
for a large and diverse population of microorganisms (called ora),
mainly bacteria. The intestine of an adult contains up to 500 different
species of bacteria. Scientists even think there may also be some species
that have not yet been identied. In normal healthy circumstances the
relationship is mutually benecial for both partners: bacteria and host
(you!).
2
*
Major functions of the intestinal ora include:
2
*
activities that result in the release of absorbable nutrients and
substances that can be used for energy
protection of the host against invasion by alien ora
A healthy lower gastrointestinal tract contributes to a healthy intestinal
environment and helps maintain proper gastrointestinal ora.*
How Wormwood Complex Keeps You Healthy
Cleanses the lower gastrointestinal tract
In Western civilization, Wormwood has been known since ancient times
to cleanse the lower gastrointestinal tract (especially the large intestine).
References to this plant appear in the writings of the ancient Egyptians, in
early Syrian texts and in the Bible. Early European texts refer to it for this
purpose and as a tonic. (It is said to have been brought to central Europe
from the south by the early Christian monks.) Wormwood was published
in an ofcial list of therapeutic plants in Canada in 1868, and in the United
States in 1830. Wormwood is now used traditionally around the world.
3-7
*
Stemona root and the green hull of Black Walnut fruit are used
traditionally to help cleanse the lower gastrointestinal tract.
8-10
*
Supports healthy bowel function
Clove Bud essential oil has been used traditionally to support healthy
bowel function. It may do this by helping produce regular peristaltic
action. (Peristalsis is the process by which the contents of the
gastrointestinal tract are pushed along (propelled). The muscular layers
of the gastrointestinal tract do this by producing alternating contractions.)
By making peristalsis more regular Clove Bud essential oil helps cleanse
the bowel.
11,12
The normal propulsive action also helps to maintain proper
intestinal ora.
2
*
Supplement Facts
Calories 2
Calcium 18 mg 2%
Stemona root 5:1 extract 200 mg

from Stemona sessilifolia root 1.0 g
Black Walnut green hulls 4:1 extract 25 mg

from Juglans nigra green hulls 100 mg
Wormwood herb 4:1 extract 25 mg

from Artemisia absinthium herb 100 mg
Clove bud (Syzygium aromaticum)
essential oil 20 mg

Other ingredients: Cellulose, silica, calcium acid phosphate, sodium starch
glycollate, hypromellose and magnesium stearate.
Caution: Contraindicated in pregnancy and lactation.
Product No Content
M1490 120 Tablets
Wormwood Complex
M1490
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The intestinal ora also break down undigested matter in the feces, which produces gases. This
can contribute to atulence (or wind).
1
Clove Bud essential oil has been used traditionally in
this way to support healthy bowel function.
10,12
*
Wormwood has been used to support healthy bowel function by promoting efcient
gastrointestinal elimination.
4
*
Stimulates digestion
Wormwood is traditionally used to stimulate digestion and promote the healthy ow of digestive
enzymes. The ability of Wormwood to do this also supports healthy bowel function and a healthy
intestinal environment.
4,5,13
*
What Makes Wormwood Complex Unique
Wormwood Complex is unique in the professional herbal products industry because:
Top quality organically grown Wormwood and wildcrafted Black Walnut Hulls are used in the
manufacture of this tablet
MediHerb tests the quantity of essential oil in Wormwood raw material
The formula was prepared after research in 2002 in conjunction with Australian university
and government scientists, who investigated how the individual ingredients and formula
might benet intestinal health and help maintain proper intestinal ora in sheep
Unique extraction method using cold percolation for the Wormwood and Black Walnut Hulls
components of this tablet (this protects the delicate plant constituents, ensuring a full range
of constituents)
References
1
Lazaroff M. The Complete Idiots Guide to Anatomy & Physiology. Alpha, Indianapolis, 2004.
2
Guarner F. Digestion 2006; 73(Suppl 1): 5-12
3
Quinlan MB, Quinlan RJ, Nolan JM. J Ethnopharmacol 2002; 80(1): 75-83
4
Holmes P. The Energetics of Western Herbs: Treatment Strategies Integrating Western and Oriental Herbal Medicine, Volume 1, Revised 3rd Edn.
Snow Lotus Press, Boulder, 1997.
5
British Herbal Medicine Associations Scientic Committee. British Herbal Pharmacopoeia. BHMA, Bournemouth, 1983.
6
Erichsen-Brown C. Medicinal and Other Uses of North American Plants: A Historical Survey with Special Reference to the Eastern Indian Tribes.
First published 1979, reprinted Dover Publications, New York, 1989.
7
Boyle W. Ofcial Herbs: Botanical Substances in the United States Pharmacopoeias 18201990. Buckeye Naturopathic Press, East Palestine, Ohio,
1991.
8
World Health Organization. Medicinal Plants in Viet Nam. WHO Regional Ofce for the Western Pacic, Manilla, 1990.
9
Pei SJ. J Ethnopharmacol 1985; 13(2): 121-137
10
Felter HW, Lloyd JU. Kings American Dispensatory. 18th Edn, 3rd revision, Volume 1. First published 1905, reprinted Eclectic Medical Publications,
Portland, 1983.
11
Brunton TL. A Textbook of Pharmacology, Therapeutics, and Materia Medica. Adapted to the United States Pharmacopoeia by FH Williams.
MacMillan and Co, London, 1885.
12
Reynolds JEF (ed). Martindale: The Extra Pharmacopoeia, 26th Edn, The Pharmaceutical Press, London, 1973.
13
Mills S. The Dictionary of Modern Herbalism. Thorsons, London, 1989.

Page 29
GF

This product contains less than 10 parts per million of gluten per serving size or less than 20 parts per million per the suggested use listed on each product label.
Zymex

II
Contains Important Digestive Enzymes to Support Healthy
Gastrointestinal Function
The word enzyme comes from Greek words that mean in yeast. Enzymes were
given this name when they were discovered while scientists were studying the
process of fermentation.
Enzymes help sustain life. Almost every chemical reaction that takes place in all
living cells of plants, animals, humans, and even of some bacteria begins by the
stimulation of some specic enzyme. Enzymes are catalysts, meaning they speed
up chemical reactions without changing themselves. They are the catalysts that
set off multitudes of specic activities and processes throughout the human
body. While hundreds of different enzymes have been discovered to date, each
enzyme performs a singular function. Although the enzymes are each
responsible for initiating a process that only that particular enzyme can
accomplish, they are related to one another enough to allow classication into
one of six categories. The proteolytic enzymes, for example, work to break down
proteins in the digestive tract.
How Zymex II Keeps You Healthy
Promotes healthy digestive function
As food is taken into the mouth and begins its journey down the alimentary
tract, it is met by a series of different enzymes. Each is responsible to initiate a
different chemical reaction in the digestive process and each is dependent upon a
certain acid or alkaline environment in order to perform its respective function.
The human body requires adequate amounts of these digestive enzymes in order
to break down ingested nutrients into substances suitable for absorption. The
proteolytic enzymes work in the digestive system and at the cellular level to help
digest proteins. Zymex II contains the proteolytic enzymes papain and
bromelain, which are historically isolated from papaya and pineapple,
respectively. In addition to proteolytic enzymes, Zymex II also contains amylase,
another hydrolytic enzyme that triggers the process of breaking down starch into
smaller carbohydrate molecules. Zymex II also contains lipase, an enzyme
produced by organs of the digestive system to stimulate the breakdown of lipids.
Provides alkaline-based digestive support for the acid-sensitive individual

All enzymes, whether of the proteolytic variety or not, are extremely sensitive to
acid and alkaline surroundings. Zymex II contains bromelain and papain. Both
enjoy an optimum pH value of between 6 and 7.5 and remain stable in
temperatures of up to 60 and 80 C. These characteristics offer the acid-sensitive
individual digestive support without adding acid to the body.
Z
y
m
e
x

I
I
Introduced in 1958
GF
Content:
40 capsules
150 capsules
Suggested Use: Two capsules between meals,
twice daily, or as directed.
Supplement Facts:
Serving Size: 2 capsules
Amount
per Serving %DV
Calories 4
Total Carbohydrate 1 g <1%*
2,000-calorie diet.
Defatted almond (nut), g (fruit), papain,
bromelain, amylase, lipase, and cellulase.
Other Ingredients: Gelatin, water, maltodextrin,
and colors.
Page 30
Zymex

II
What Makes Zymex II Unique
Product Attributes
Contains proteolytic enzymes and synergists
Papain and bromelain supported by other enzymes like amylase and lipase, as
well as the whole food synergists almond and g
Does not contain pancreatin or betaine hydrochloride
Developed for the acid-sensitive individual

The nutrients in Zymex II are processed to remain intact, complete
nished products
supplement facts for Zymex
II.
Dictionary. 5th ed. St. Louis, MO: Mosby: 80, 946.
Balch J.F., Balch P.A. 1997. Prescription for Nutritional Healing. 2nd
ed. Garden City Park, NY: Avery Publishing Group: 87, 108-109, 341,
354, 361.
Canaan S., et al. 1999. Gastric lipase: crystal structure and activity.
Biochemical Biophysical Acta 1441(2-3): 197-204.
Clemetson C.A., et al. 1978. Estrogens in food: the almond mystery.
International Journal of Gynaecology and Obstetrics 15(6): 515-521.
Han W.G., et al. 1999. QM/MM study of the active site of free papain and
of the NMA-papain complex. Journal of Biomolecular Structural
Dynamics 16(5): 1019-1032.
Henderson T.R., et al. 1998. Effect of pasteurization on long chain
polyunsaturated fatty acid levels and enzyme activities of human milk.
Journal of Pediatrics 132(5): 876-878.
Luz S., et al. 1997. Current concepts of digestion and absorption of
carbohydrates. Arq Gasterenterol 34(3): 175-185.
Monograph: Bromelain. Alternative Medicine Review. 1998. 3(4):
302-305.
Monter B., et al. 1991. Kinetically controlled synthesis of dipeptides using
cin as biocatalyst. Biotechnological Applications in Biochemistry
14(2): 183-191.
Ohmori T., Yang R.Y. 1996. Self-sustained pH oscillations in immobilized
proteolytic enzyme systems. Biophysical Chemistry 59(1-2): 87-94.
Pitchford P. 1993. Healing with Whole Foods, Oriental Traditions and
Modern Nutrition. Revised ed. Berkeley, CA: North Atlantic Books: 127,
130, 148, 178, 492, 578, 581-582, 618.
Spiller G.A., et al. 1998. Nuts and plasma lipids: an almond-based diet
lowers LDL-C while preserving HDL-C. Journal of the American
College of Nutrition 17(3): 285-290.
Page 31
GF

Introduced in 1963
GF
Content:
40 capsules
150 capsules
or as directed.
Supplement Facts:
Amount
per Serving %DV
Calories 2
Cholesterol 5 mg 2%
Fig (fruit), defatted almonds, pancreatin (3x),
fatty acids, bromelain, lipase, cellulase, papain,
and amylase.
Other Ingredients: Gelatin, lactose (milk),
maltodextrin, water, colors, and calcium
stearate.
Each capsule supplies approximately: 175 mg
pancreatin (3x).
Multizyme
Contains Digestive Enzymes to Support the Proper Breakdown

and Absorption of Proteins, Carbohydrates, Sugars, and Fats
Enzymes are protein molecules that catalyze, or jump-start, nearly all
biochemical activity in the body. Enzymes are needed to digest food, produce
energy inside cells, activate the brain, help the body maintain cells, tissues, and
organs, plus support other functions of the body. Without enzymes, many
chemical reactions in the body would not be supported. Enzymes have unique
chemical structures and perform specic tasks, so one enzyme cannot substitute
for another. Enzymes fall into two main categories: digestive or metabolic. The
digestive enzymes work in the intestinal tract to break down the foods we eat, so
nutrients can be absorbed into the blood for use in the body. Digestive enzymes
are divided into amylases, proteases, and lipases. Amylases are found in saliva
and pancreatic juice. The sole responsibility of amylases is to break down
carbohydrates and sugars for absorption. Proteases are found in pancreatic,
stomach, and intestinal juices and are responsible for digesting proteins. Lipases
break down fats and are found in the stomach and pancreatic juices, as well as in
foods that contain fat. The body procures some enzymes from food. Raw foods
from both plant and animal sources provide the greatest percentage of enzymes,
since heat and cooking can destroy these sensitive molecules. Digestive enzymes
enable our bodies to obtain optimal nutritional benet from the foods we eat.
Multizyme is an enzyme supplement that can aid in digestion.
How Multizyme Keeps You Healthy

Supports the proper and efcient breakdown of foods and absorption of nutrients
While the solid foods and liquids we eat every day contain the vital nutrients our
bodies need to operate normally, they are of no use unless they can be absorbed
into the bloodstream. Digestive enzymes ensure that proteins, carbohydrates,
sugars, and fats are chemically transformed into molecules that can be absorbed
and used by the tissues of the body.
Figs and almonds contribute fatty acids, ber, and vitamins and minerals that
encourage healthy digestion. The proteolytic enzyme pancreatin is a concentrate
of important pancreatic enzymes needed to break down dietary proteins, fats,
and starch into amino acids, glycerol and fatty acids, and simple sugars,
respectfully. Bromelain and papain are proteolytic enzymes from plants that help
the body digest proteins. Lipases trigger lipid breakdown while cellulases work
together to hydrolyze cellulose. Amylase sparks the hydrolysis of starch into
smaller mono- and polysaccharide carbohydrate molecules. Together, enzymes
in Multizyme work synergistically to encourage the efcient breakdown of food
in the digestive tract and enhance the absorption of vital nutrients.
M
u
l
t
i
z
y
m
e
Page 32
supplement facts for Multizyme
.
Dictionary. 5th ed. St. Louis, MO: Mosby: 80, 290, 619, 946, 1193,
1196.
Balch J.F., Balch P.A. Prescription for Nutritional Healing. 2nd ed. Garden
City Park, NY: Avery Publishing Group: 47-48.
Boyer P.D. 1971. The Enzymes. 3rd ed. New York, NY: Academic Press:
485-546.
Dressler D., Potter H. 1991. Discovering Enzymes. New York, NY: Scientic
American Library: 7-13.
Fisher M., LaChance P. 1999. Nutrition & Health Aspects of Almonds.
Modesto, CA: Almond Board of California: 1-7.
Fraser G.E. 1999. Nut consumption, lipids, and risk of a coronary event.
Clinical Cardiology 22(7): III11-III15.
Fruton J.S. 1999. Proteins, Enzymes, Genes the Interplay of Chemistry
and Biology. New Haven, CT: Yale University Press: 223.
Goodwin T.W., Harris J.I., Hartley B.S. 1964. Structure and Activity of
Enzymes. New York, NY: Academic Press.
Harrow B. 1950. One Family: Vitamins, Enzymes, Hormones.
Minneapolis, MN: Burgess Publishing Company: 55-74.
Laidler K.J. 1954. Introduction to the Chemistry of Enzymes. New York,
NY: McGraw-Hill Book Company, Inc: 1-2, 34-59.
Masson M. 1995. Fortschr Med 113(19): 303-306.
Mazda T., et al. 1995. Use of standardized protease enzymes for antibody
screening of blood donor samples with the microplate system
AutoAnalyzer. Transfusion Medicine 5(1): 43-50.
Metzig C., et al. 1999. Bromelain proteases reduce human platelet
aggregations in vitro, adhesion to bovine endothelial cells and thrombus
formation in rat vessels in vivo. In Vivo 13(1): 7-12.
Mihalyi E. 1972. Application of Proteolytic Enzymes to Protein Structure
Studies. Cleveland, OH: CRC Press: 39-101.
Monograph: Bromelain. 1998. Alternative Medicine Review 3(4):
302-305.
Nuts Are Back! Mediterranean Diet Pyramid Says Eat Nuts Daily.
1998-2000. Sacramento, CA: Blue Diamond Growers: 1-4.
Palmer T. 1995. Understanding Enzymes. 4th ed. New York, NY: Prentice
Hall/Ellis Horwood: 3-11, 74.
Pitchford P. 1993. Healing With Whole Foods. Revised ed. Berkeley, CA:
North Atlantic Books: 50, 68, 78, 163, 227, 275, 578.
Price N.C., Stevens L. 1989. Fundamentals of Enzymology. 2nd ed.
Oxford, NY: Oxford University Press: 473.
Samuelson A. Phytochemicals In Nuts: New Science With Great
Promise. California Almond Board: Ketchum Public Relations.
Spiller G.A., Bruce B. 1997. Nuts and healthy diets. Vegetarian Nutrition
1(1): 12-16.
Starley I.F., et al. 1999. The treatment of paediatric burns using topical
papaya. Burns 25(7): 636-639.
Subbarayan P.R., et al. 1997. Report on a patient with paroxysmal cold
hemoglobinuria. International Journal of Hematology 65(2): 165-167.
Turk B., et al. 1997. Structural and functional aspects of papain-like
cysteine proteinases and their protein inhibitors. Biological Chemistry
378(3-4): 141-150.
Whitaker J.R. 1994. Principles of Enzymology for the Food Sciences.
2nd ed. New York, NY: Marcel Dekker, Inc: 469-493, 499-511.
Multizyme
What Makes Multizyme Unique

Product Attributes
Combines multiple digestive enzymes with fatty acids and ber to stimulate
the proper digestion of macronutrients and support gastrointestinal health

nished products
Page 33
GF

Collinsonia Root
Combines Strong Antioxidant Properties With a
Natural Afnity to Support Vascular Tissue
Different parts of the collinsonia plant can be taken internally or applied
topically, depending on the indication for use. The Chinese have used different
parts of Collinsonia canadensis for centuries to help support the liver, lungs,
colon, and brous tissue surrounding the heart. The benecial chemical
elements found in collinsonia root include saponins, resin, tannin, organic acid,
and mucilage.
How Collinsonia Root Keeps You Healthy

Supports healthy blood vessel tone and uid levels
Collinsonia encourages vascular tissue contraction and moves blood or body
uids through the vessels to maintain healthy uid levels.
Promotes digestive efciency

Collinsonia has historically been used to help support gastrointestinal health.
Helps maintain heart and lung health

Similar to its ability to help move blood and body uids, collinsonia also helps
maintain heart and lung health. Collinsonia works to keep mucus membranes
healthy, which in turn helps the lungs work more efciently.
Helps maintain a healthy urinary system

Collinsonia naturally helps the body eliminate excess uid and byproducts from
tissues throughout the body. These cleansing characteristics give collinsonia the
ability to help maintain a healthy environment in the urinary system.
C
o
l
l
i
n
s
o
n
i
a

R
o
o
t
Introduced in 1955
GF
Content:
150 capsules
Suggested Use: Two capsules with a full
glass of water twice a day, between meals,
or as directed.
Supplement Facts:
Serving Size: 2 capsules
Amount
per Serving %DV
Calories 3
Collinsonia (Root) 600 mg
Ingredients: See Supplement Facts.
Other Ingredients: Gelatin, water, calcium
stearate, and colors.
Page 34
Collinsonia Root
What Makes Collinsonia Root Unique
Product Attributes
Each capsule supplies 300 mg of collinsonia-root powder
All the benets of whole foods in a convenient form
The nutrients in Collinsonia Root are processed to remain intact, complete
nished products
supplement facts for Collinsonia Root.
Dictionary. 5th ed. St. Louis, MO: Mosby: 59, 107, 139, 246, 1056,
1406, 1448.
Duke J.A., Foster S. 1990. Medical Plants ( Eastern/Central), Peterson
Field Guides. Boston, MA: Houghton Mifin: 112-113.
Frawley D., Lad V. 1992. The Yoga of Herbs. 3rd ed. Twin Lakes, WI:
Lotus Press: 215.
Hoffmann D.L. 1995. The New Holistic Herbal. Britain: Barnes & Noble
(special edition by arrangement with Elemental Book Limited): 235.
Lewis W.H., Elvin-Lewis P.F. 1977. Medical Botany: Plants affecting
Mans Health. New York, NY: John Wiley & Sons: 312-313.
Stevens J.F., et al. 1999. A novel 2-hydroxyavone from Collinsonia
canadensis. J Nat Prod 62(2): 392-394.
Tierra M. 1988. Planetary Herbology. Boston, MA: Lotus Press: 283-284.
Winston D. 1999. Herbal Therapeutics: Specic Indications For Herbs &
Herbal Formulas. 6th ed. Herbal Therapeutics Research Library: 37.
Page 35
GF

Introduced in 1998
GF
Content:
90 capsules
Suggested Use: One capsule per day,
or as directed.
Supplement Facts:
Amount
per Serving %DV
Calories 3
Vitamin K 4 mcg 4%
Potassium 10 mg <1%
Kale 300 mg
Brussels sprouts 300 mg
Other Ingredients: Gelatin, water, calcium
stearate, and colors.
Contains Organically Grown, Minimally Processed

Kale and Brussels Sprouts
Research demonstrates that cruciferous vegetables, such as kale and Brussels
sprouts, contain important phytonutrients that help protect against free radicals,
the highly unstable molecules that can damage cells and genetic material.
Cruciferous vegetables are nutrient-dense foods packed with many essential
vitamins, minerals, and antioxidants. Cruciferous vegetables also contain
important health-promoting nutrients like carotenoids and other phytochemicals
that stimulate enzymatic activity to support liver detoxication.

How Cruciferous Complete Keeps You Healthy
Furnishes many nutrients to support health
Cruciferous Complete contains kale and Brussels sprouts, which contain a broad
spectrum of micronutrients, including vitamins B
6
, C, and K; dietary ber;
copper; calcium; and potassium. A class of plant pigments, called carotenoids, is
also found in crucifers. These pigments, including beta carotene and lutein, serve
important roles within the body. Beta carotene is a precursor to vitamin A, while
lutein is found in abundance in the retina of the eye. Carotenoids and other
phytochemicals also have antioxidant properties and can protect cells from
damage of excess reactive oxygen species.
Provides antioxidant support

The health-promoting phytochemicals in cruciferous vegetables protect cells
against free-radical damage and have been shown in the laboratory to alter the
metabolic pathways responsible for the metabolism of hormones in cultured
cells and in mice.

Induces liver detoxication enzymes
Cruciferous vegetables contain highly active phytochemicals called
glucosinolates. In laboratory cell cultures and mice, products left from the
breakdown of glucosinolates stimulate the phase I and phase II liver enzymes,
two biochemical pathways in the liver involved in converting toxins into
harmless substances that can easily be excreted from the body.

C
r
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c
i
f
e
r
o
u
s

C
o
m
p
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e
Page 36
What Makes Cruciferous Complete Unique

Product Attributes
Each capsule supplies 300 mg each of organically grown kale and
Brussels sprouts
Unique Processing
promptly processed
The nutrients in Cruciferous Complete are processed to remain intact,
complete nutritional compounds
nished products
supplement facts for Cruciferous Complete.
Auborn, K. J., Fan, S., Rosen, E. M., Goodwin, L., Chandraskaren, A.,
Williams, D. E., et al. (2003). Indole-3-carbinol is a negative regulator of
estrogen. J Nutr, 133(7 Suppl), 2470S-2475S.
Hecht, S. S. (1999). Chemoprevention of Cancer by Isothiocyanates,
Modiers of Carcinogen Metabolism. J. Nutr., 129(3), 768.
Hecht, S. S. (2000). Inhibition of carcinogenesis by isothiocyanates. Drug
Metab Rev, 32(3-4), 395-411.
Holick, C. N., Michaud, D. S., Stolzenberg-Solomon, R., Mayne, S. T.,
Pietinen, P., Taylor, P. R., et al. (2002). Dietary carotenoids, serum beta-
carotene, and retinol and risk of lung cancer in the alpha-tocopherol,
beta-carotene cohort study. Am J Epidemiol, 156(6), 536-547.
Holst, B., Williamson, G. (2004). A critical review of the bioavailability of
glucosinolates and related compounds. Nat Prod Rep, 21(3), 425-447.
Institute of Medicine Food and Nutrition Board. (2000). Beta-carotene and
other carotenoids. In Dietary reference intakes for vitamin C, vitamin
E, selenium, and carotenoids (pp. 325-400). Washington D.C.:
National Academy Press.
International Agency for Research on Cancer. (1998). IARC Handbooks
of Cancer Prevention: Carotenoids. Lyon: International Agency for
Research on Cancer.
Johnston, N. (2004). Sulforaphane halts breast cancer cell growth. Drug
Discovery Today, 9(21), 908.
Keck, A.-S., & Finley, J. W. (2004). Cruciferous Vegetables: Cancer
Protective Mechanisms of Glucosinolate Hydrolysis Products and
Selenium. Integr Cancer Ther, 3(1), 5-12.
Krinsky, N. I., Landrum, J. T., & Bone, R. A. (2003). Biologic mechanisms
of the protective role of lutein and zeaxanthin in the eye. Annu Rev Nutr,
23, 171-201.
Kristal, A., Lampe JW. (2002). Brassica vegetables and prostate cancer risk:
a review of the epidemiological evidence. Nutr Cancer, 42(1), 1-9.
Liu, R. H. (2004). Potential Synergy of Phytochemicals in Cancer Prevention:
Mechanism of Action. J. Nutr., 134(12), 3479S-3485.
Mares-Perlman, J. A., Millen, A. E., Ficek, T. L., & Hankinson, S. E. (2002).
The body of evidence to support a protective role for lutein and zeaxanthin
in delaying chronic disease. Overview. J Nutr, 132(3), 518S-524S.
Munday, R., & Munday, C. M. (2004). Induction of phase II detoxication
enzymes in rats by plant-derived isothiocyanates: comparison of allyl
isothiocyanate with sulforaphane and related compounds. J Agric Food
Chem, 52(7), 1867-1871.
Olson, J. A. (1999). Carotenoids and human health. Arch Latinoam Nutr,
49(3 Suppl 1), 7S-11S.
Rao, A. V., & Rao, L. G. (2007). Carotenoids and human health. Pharmacol
Res, 55(3), 207-216.
Telang, N. T., Katdare, M., Bradlow, H. L., Osborne, M. P., & Fishman, J.
(1997). Inhibition of proliferation and modulation of estradiol metabolism:
novel mechanisms for breast cancer prevention by the phytochemical
indole-3-carbinol. Proc Soc Exp Biol Med, 216(2), 246-252.
van Poppel, G., Verhoeven, D. T., Verhagen, H., & Goldbohm, R. A.
(1999). Brassica vegetables and cancer prevention. Epidemiology and
mechanisms. Adv Exp Med Biol, 472, 159-168.
Verhoeven, D. T., Goldbohm, R. A., van Poppel, G., Verhagen, H., van den
Brandt, P. A. (1996). Epidemiological studies on Brassica vegetables and
cancer risk. Cancer Epidemiol Biomarkers Prev, 5(9), 733-748.
Walters, D. G., Young, P. J., Agus, C., Knize, M. G., Boobis, A. R.,
Gooderham, N. J., et al. (2004). Cruciferous vegetable consumption
alters the metabolism of the dietary carcinogen 2-amino-1-methyl-
6-phenylimidazo[4,5-b]pyridine (PhIP) in humans. Carcinogenesis,
25(9), 1659-1669.
Young, A. J., & Lowe, G. M. (2001). Antioxidant and prooxidant properties of
carotenoids. Arch Biochem Biophys, 385(1), 20-27.
Zhang, Y. (2004). Cancer-preventive isothiocyanates: measurement of
human exposure and mechanism of action. Mutat Res, 555(1-2),
173-190.
Ziegler, R. G. (1989). A review of epidemiologic evidence that carotenoids
reduce the risk of cancer. J Nutr, 119(1), 116-122.
Page 37
Passion Flower (|o|h^|o ||co||o|o)
||||^^|e| o|J |eoc|e| |oJ^|l '|e||e| ^|ce
o|J ||o| l^| eve|y |o|o| ||||e ^|ew|e|e
|| ||e w^||J ||e|e e|| o |o|| w||c| | ||e
co|e. | |e||eve ||o| ||e|e | o |eo||| ^|e|||o|
|^c|eJ |||Je |o|| w||c| | |||e|o| w||| ||e||
ev^|o||^| |o| o || | o|| ^l |o|o| ev^|o||^| |^
|eo|| |^ |o ||| w^|Je|lo| |l| ^l No|o|e.
Garlic Forte: Active Release
Garlic clove (or bulb) has been used therapeutically for over 3500 years.
ll | a|o uec || mol cu|lu|e o l|e wo||c lo |ov|ce a c|l||cl|ve havo|
to food.
1,2
There is much written about the history of garlic use. Garlic
was fed to laborers in ancient Egypt, perhaps to help them maintain their
strength. During some of the earliest Olympic Games (in ancient Greece)
athletes were fed garlic before they competed. During the Middle Ages
garlic became available in Europe after the Roman legions moved north.
Garlic was grown in monasteries during Medieval times. Garlic grew
freely in the woods of North America and native Americans used garlic in
their tea.
3
*
Garlic constituents: the all important organic sulfur compounds
Garlic is a complex herb, and contains hundreds of constituents. Many
of these constituents give garlic its characteristic smell; they are sulfur-
containing organic compounds. By 1998 it became apparent from clinical
luc|e l|al o| ol|ma| ecac,, a|||c |ocucl |ou|c co|la|| u|la|l|a|
levels of the important sulfur compound alliin.
4
There are many types
of garlic products available on the market: fresh (raw) garlic, dried
garlic (garlic powder), garlic oils and aged garlic extract. The range of
constituents in these products varies, as does the amount of important
constituents. Only raw garlic and very carefully dried garlic powder
contain alliin, aged garlic extract does not.
5
*
When a garlic clove is crushed, or when dried garlic powder gets wet
the odorless alliin is broken down by the enzyme alliinase. Alliin is then
converted into allicin and other strong smelling sulfur compounds.
4
*
Garlic products: is the allicin available for absorption in the body?
Because stomach acid can degrade alliinase, quality garlic powder
products should be enterically coated. This type of coating protects
the tablet (and the enzyme, alliinase) from being broken down in the
stomach. (If alliinase became degraded, allicin would not be produced
from alliin.) When enterically coated, the tablet survives intact and enters
the intestine. Providing the tablet has a properly formulated coating, it is
able to break down in the non-acidic environment of the small intestine
and the enzymatic reaction can occur. Allicin is produced and can then
be absorbed in the large intestine. If the enteric coating cannot break
down in the intestine, allicin will not be produced, and then cannot
be absorbed.
2
It is possible in the laboratory to measure the amount
of allicin released from garlic tablets. This is called under simulated
gastrointestinal conditions.
6
*
Supplement Facts
Calories 2
Calcium 90 mg 9%
Garlic Bulb 12:1 extract 300 mg

from Allium sativum bulb 3.6 g
Containing alliin 12 mg

Other ingredients: Calcium hydrogen phosphate, cellulose, sodium starch
glycollate, garlic bulb powder, enteric coating, magnesium stearate, silica and
d-alpha-tocopherol.
Caution: Contraindicated in known cases of allergy to Garlic. Contraindicated
in lactation. Not to be used during pregnancy unless otherwise directed by a
(ua||ec |ea|l| ca|e |oe|o|a|.
Product No Content
M1285 40 Enteric Coated Tablets
Garlic Forte
M1285
Alliin: The compound found in raw and
carefully dried garlic powder
Allicin: The active ingredient formed from
alliin in the small intestine
Alliinase: The delicate enzyme required for the
conversion of alliin to allicin
G
a
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c

F
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M
1
2
8
5
Page 38
Why use top quality herbal products from a reliable manufacturer?
Co|ume| |eec lo |e co|ce|l o l|e ||le||l, o l|e |e||a| ma|uaclu|e| lo e|u|e l|al l|e
product contains the stated amount of important constituents. Labels of garlic products that report
allicin content are probably reporting potential allicin not actual allicin. So the amount of allicin
delivered to the body is not guaranteed.
2
The amount of alliin converted to allicin can be as little
as 10%. Conversion depends on the amount and activity of the alliinase.
7
*
The activity of alliinase may be substantially decreased, for example, by:
8
*
processing garlic bulb into a powder (eg with the use of heat)
the presence of other compounds in the tablet
incorrect disintegration of the tablet (because of its coating)
But there are more quality issues that consumers need to be concerned with, such as:*
How much alliin is in the raw material?
Is the enzyme (alliinase) present and able to do the conversion (alliin allicin)?
Will the alliinase survive the acidic environment of the stomach (is the tablet enteric-coated?)
If enteric-coated, will the tablet disintegrate correctly in the intestine liberating the (protected)
alliinase, allowing the conversion to occur and providing the allicin for absorption?
How Garlic Forte Keeps You Healthy
Supports cardiovascular system health
Garlic has been used traditionally to support cardiovascular health.
3
Many clinical trials have been
co|cuclec lo ||vel|ale l|ee eecl o a|||c, |ul l|e |eu|l a|e co|h|cl||,
6
probably because
of the unknown quality of the garlic products that were evaluated.
1
But more importantly, because
the allicin release from the tablets was not known.
6
*
An analysis of the results of 29 placebo-controlled trials to November 2007 found that garlic helps
maintain normal cholesterol and triglyceride levels already within a normal range.
9
One of these
trials, which found positive results, reported the amount of allicin released from the tablet under
simulated gastrointestinal conditions: 9.6 mg of allicin in the daily dose.
5,10
Several trials using top
(ua||l, a|||c la||el u||||ec ||ce l|| cale |ave co||mec l|| acl|v|l,.
11-13
*
Alliin
Alliinase
Allicin
Reaction of Garlic powder with
alliinase to form allicin by HPLC
Peak due to alliin
has disappeared
due to conversion
to allicin
The top diagram illustrates
the chemical conversion of
alliin to allicin by alliinase.
The bottom diagram
illustrates how the alliin
to allicin conversion can
be verhed usng hgh
Performance Liquid
Chromatography (hPLC).
hPLC s a sophstcated
testing method used
routneIy by Medherb.
Page 39
The brand of garlic tablet used in most of the clinical trials from 1994 to 2000 was tested
by researchers from Utah in 2001. They found that the allicin release under simulated
gastrointestinal conditions varied from 14% to 18% of the allicin potential. (Allicin potential
is the amount that should be released based on the alliin content.)
5,6
These results strongly
suggest that to be effective, garlic tablets need to be standardized for alliin content and
release allicin under simulated gastrointestinal conditions.*
Garlic also supports the cardiovascular system in other ways.*
Double-blind, placebo-controlled trials have shown that allicin-releasing garlic powder
helps the blood to have healthy platelet function.
14,15
Healthy platelet function is
|ecea|, o| a |ea|l|, ||ooc how a|c l|e co|l||u|| |ea|l| o l|e ||ooc vee|.
Double-blind, placebo-controlled trials conducted to the end of June 2008 found that
standardized garlic powder tablets helped maintain normal blood pressure already within
a normal range.
16
*
Sla|ca|c|ec a|||c owce| la||el wa a|o ou|c lo |m|ove ||ooc how lo l|e ||| a|c
tissues in healthy volunteers.
14,17
*
Another well-designed trial and further research has found that garlic helps keep the walls
of the blood vessels healthy in a similar way to HDL-cholesterol. (HDL-cholesterol is the good
cholesterol in your body.)
18,19
*
Promotes health in the gastrointestinal system
Population studies that involved people in Italy and Switzerland (19912004) found that garlic
in the diet was associated with a healthy gastrointestinal tract (mouth, pharynx, esophagus,
larynx and large bowel). The analysis compared the health of people eating high amounts of
garlic with those eating none or a low amount.
20
Scientists think that the sulfur compounds in
a|||c a|e |mo|la|l o| l|ee |e|ec|a| eecl.
21
*
During World War I garlic was used to help ensure intestinal health in soldiers stationed in
the Balkans.
22
In 1941, an American clinician conducted an unblinded, controlled trial and
ou|c a|||c |e|ec ma||la|| |oe| al|o||lel||a| ho|a || l|oe w|l| a ||lo|, o oo|
gastrointestinal function.
23
In a 1991 uncontrolled trial in Egypt, it was found that garlic
promoted intestinal health and normal stools in children.
24
*
Enhances immune system response and promotes healthy lung function
|u||| l|e |l ce|lu|,, l|e oc|a| /|m, |,|c|a| ||oco||ce ec|ec l|al a|||c |e la|e|
by Roman soldiers to support a healthy response in the lungs.
25
More recently, garlic has been
used traditionally to support healthy lung function. It may do this by stimulating the mucous
membranes and promoting healthy secretions in the lung.
26-28
*
In the 1980s Russian newspapers advised the chewing of raw garlic to enhance normal
immune response in the upper respiratory tract.
26
In World War II, the Soviet army also used
garlic to enhance normal immune response.
29
Volunteers taking a garlic tablet were more
likely to stay healthy during the winter months and have healthy respiratory tract function
than those taking placebo. This randomized, double-blind study was conducted in England and
published in 2001.
30
*
P|ov|des ant|ox|dant suppo|t and he|ps no|ma| metaho||c detox|cat|on
Antioxidants help protect cells from the damaging effects of excessive free radicals. Free
radicals are highly reactive substances created in the body that may injure cells.*
Garlic taken for 1-2 months improved the level and activity of antioxidant enzymes in the red
blood cells of healthy volunteers.
31,32
*
keea|c| uel l|al ue o a|||c uo|lec l|e |oc, |o|ma| celo:|cal|o| |ocee o
potentially detrimental dietary substances in healthy volunteers.
33
*
Page 40
|, e:e|l a|c |eace| || l|e e|c o
|e||a| l|e|a,, u|| c|e|l|c ev|ce|ce
a|c |u|c|ec o ,ea| o l|ac|l|o|a|
knowledge.
|oe|o|a| wo|| w|l||| |ec||e||
w|l| a| acv|o|, |oa|c o |ea|l| ca|e
|oe|o|a| |om a|ou|c l|e wo||c.
a|e e:le||ve|, lelec o| u||l, a|c
ole|c,. |e |ec||e|| ma|uaclu|||
|a|maceul|ca| ma|uaclu||| ac|||l|e.
ae a|c eecl|ve |ocucl l|al |a
|ee| ma|uaclu|ec lo |a|maceul|ca|
standards.
\e ||ow |om ou| e:e||e|ce a |ea|l|
ca|e |oe|o|a| l|al l|e (ua||l,
o a |ocucl ,ou la|e ma|e a |ue
c|e|e|ce lo l|e |ea|l| oulcome ,ou
www.mediherb.com
What Makes MediHerb Garlic Forte Unique
Garlic Forte is unique in the professional herbal products industry because:
The label states exactly how much each tablet contains of the important plant
constituent (alliin)
MediHerb tests the quantity of alliin in garlic raw material
MediHerb tests that alliinase is present and active in garlic raw material
MediHerbs testing ensures the alliin and alliinase are retained in the product throughout
manufacture
MediHerbs testing also ensures that the alliinase is protected from stomach acid by correct
enteric coating, and the tablet disintegrates under simulated gastrointestinal conditions to
release allicin
kaw male||a| a|c |||ec |ocucl a|e u|eclec lo lou| (ua||l, la|ca|c, ||c|uc|| ue
References
1
Rahman K, Lowe GM. J Nutr 2006; 136(3 Suppl): 736S-740S
2
Cronin JR. Altern Complement Ther 2001; 7(3): 166-170
3
Rivlin RS. J Nutr 2001; 131(3s): 951S-954S
4
Lawson LD, Bauer R (eds). Phytomedicines of Europe: Chemistry and Biological Activity. ACS Symposium Series 691. American Chemical
Society, Washington DC, 1998.
5
Lawson LD, Gardner CD. J Agric Food Chem 2005; 53(16): 6254-6261
6
Lawson LD, Wang ZJ, Papadimitriou D. Planta Med 2001; 67(1): 13-18
7
Product Review: Garlic Supplements. Initial Posting: 21 June 2006, updated: 4 September 2006. Available by subscription from
www.consumerlab.com. Accessed 15 November 2006.
8
Lawson LD, Wang ZJ. J Agric Food Chem 2001; 49(5): 2592-2599
9
Reinhart KM, Talati R, White CM et al. Nutr Res Rev 2009; 22(1): 39-48
10
Kannar D, Wattanapenpaiboon N, Savige GS et al. J Am Coll Nutr 2001; 20(3): 225-231
11
Sobenin IA, Andrianova IV, Demidova ON et al. J Atheroscler Thromb 2008; 15(6): 334-338
12
Sobenin IA, Pryanishnikov VV, Kunnova LM et al. Lipids Health Dis 2010; 9: 119
13
Sobenin IA, Nedosugova LV, Filatova LV et al. Acta Diabetol 2008; 45(1): 1-6
14
Kiesewetter H, Jung F, Pindur G. Int J Clin Pharmacol Ther Toxicol 1991; 29(4): 151-155
15
Kiesewetter H, Jung F, Jung EM et al. Eur J Clin Pharmacol 1993; 45(4): 333-336
16
Reinhart KM, Coleman CI, Teevan C et al. Ann Pharmacother 2008; 42(12): 1766-1771
17
Anim-Nyame N, Sooranna SR, Johnson MR et al. J Nutr Biochem 2004; 15(1): 30-36
18
Koscielny J, Klussendorf D, Latza R et al. Atherosclerosis 1999; 144(1): 237-249
19
Vastag B. JAMA 2002; 288(11): 1342
20
Galeone C, Pelucchi C, Levi F et al. Am J Clin Nutr 2006; 84(5): 1027-1032
21
Sengupta A, Ghosh S, Bhattacharjee S. Asian Pac J Cancer Prev 2004; 5(3): 237-245
22
Harris JC, Cottrell SL, Plummer S et al. Appl Microbiol Biotechnol 2001; 57(3): 282-286
23
Weiss E. Med Rec 1941; 153: 404-408
24
Soffar SA, Mokhtar GM. J Egypt Soc Parasitol 1991; 21(2): 497-502
25
Farbman KS, Barnett ED, Bolduc GR et al. Pediatr Infect Dis J 1993; 12(7): 613-614
26
Bolton S, Null G, Troetel WM. Am Pharm 1982; NS22(8): 40-43
27
British Herbal Medicine Associations Scientific Committee. British Herbal Pharmacopoeia. BHMA, Bournemouth, 1983.
28
Felter HW, Lloyd JU. Kings American Dispensatory. 18th Edn, 3rd revision. First published 1905, reprinted Eclectic Medical Publications,
Portland, 1983.
29
Dietz DM, Varcelotti JR, Stahlfeld KR. Burns 2004; 30(6): 612-613
30
Josling P. Adv Ther 2001; 18(4): 189-193
31
Avci A, Atli T, Ergder IB et al. Gerontology 2008; 54(3): 173-176
32
Grune T, Scherat T, Behrend H et al. Phytomed 1996; 2(3): 205-207
33
Mei X, Lin X, Liu J et al. Acta Nutr Sin 1989; 11: 141-146

Page 41
GF


Cayenne Pepper
Cayenne Pepper Works as an Effective Catalyst
for Herbal and Nutritional Supplementation
Cayenne pepper, a member of the Capsicum species, can be used to enhance
avor and turn up the heat in some of our favorite dishes, or it can be ingested
for a number of health-supporting purposes. The use of cayenne pepper dates
back some 9,000 years. The Aztec Indians referred to this type of pepper as
chilli, and many Native Americans have used cayenne pepper both in cooking
and for health. Native to tropical climates, the rst archeological evidence of this
peppers cultivation was discovered in Mexico, dating back nearly 7,000 years.
Cayenne pepper was later introduced in Europe and nally transported to most
tropical, subtropical, and temperate zones around the globe. The health-related
history of cayenne pepper began with traditional Indian Ayurvedic practitioners
and continued with the Chinese, Japanese, and Korean traditional practices. The
vitamins, minerals, and compounds found in cayenne pepper work to cleanse
the system and promote overall health and well-being.
How Cayenne Pepper Keeps You Healthy

Maintains a healthy digestive system
Cayenne pepper supports digestive system function by helping to cleanse the
digestive tract and reduce gas buildup. Cayenne stimulates gastric juice output.
Gastric juice works to help break down foods in the stomach and acts as a
natural digestive agent.
Maintains healthy circulation

Cayenne pepper helps support healthy circulation and helps increase peripheral
circulation in particular. Cayenne pepper contains vitamin E, a heart-healthy
antioxidant, in a stable form. Vitamins C and K are nutrients associated with
healthy hemostatic activity. Cayenne pepper contains these nutrients plus other
synergistic cofactors that help support healthy blood ow.
Enhances metabolic efciency

Capsaicin, an important compound in cayenne pepper, helps boost energy
expenditure in the body, thereby increasing the basal metabolism rate.
Strengthens the immune system

Cayenne pepper is one of the better botanical sources of vitamin C and is often
used to induce intense sweating. Cayenne pepper also contains folic and
pantothenic acids, plus the vitamins A and B complex.
Enhances the efcacy of other herbal and nutritional supplements

Cayenne pepper is a catalyst for other herbs, primarily due to its oleoresin
content, transporting them quickly to where they are needed most.
C
a
y
e
n
n
e

P
e
p
p
e
r
Introduced in 2001
GF

V
Content:
150 capsules
Suggested Use: One capsule per day,
or as directed.
Supplement Facts:
Amount
per Serving %DV
Calories 2
Cayenne Pepper 350 mg
(Capsicum annuum)
35,000 Scoville units
Other Ingredients: Cellulose, water, and
calcium stearate.
Caution: Exceeding recommended dosage may
cause stomach irritation. Keep out of reach of
children. Avoid contact with injured or open
skin. Avoid use during pregnancy and lactation.
Contraindicated with pepper, celery, mugwort,
and birch-pollen allergies.
Page 42
Cayenne Pepper
What Makes Cayenne Pepper Unique
Product Attributes
Each capsule contains 350 mg (35,000 Scoville units) of cayenne pepper
The nutrients in Cayenne Pepper are processed to remain intact, complete
nished products
supplement facts for Cayenne Pepper.
Dictionary. 5th ed. St. Louis, MO: Mosby: 258.
Balch J.F., Balch P.A. 1997. Prescription for Nutritional Healing. 2nd ed.
Garden City Park, NY: Avery Publishing Group: 67.
Borrelli F., Izzo A.A. 2000. The plant kingdom as a source of anti-ulcer
remedies. Phytotherapy Research 14(8): 581-591.
Cayenne. http://www.herbsrst.com/NewsLetters/0299cayenne.html.
Online. 24 Oct 2000.
Iorizzi M., et al. 2001. New glycosides from Capsicum annum L. var.
acuminatum. Isolation, structure determination, and biological activity.
Journal of Agriculture and Food Chemistry 49(4): 2022-2029.
Mills S., Bone K. Principles and Practice of Phytotherapy. New York,
NY: Churchhill Livingstone: 13, 41-42, 141, 171, 175, 178,
203, 215.
Pitchford P. 1993. Healing with Whole Foods, Oriental Traditions and
Modern Nutrition. Revised ed. Berkeley, CA: North Atlantic Books: 29,
350, 352, 354.
Rau E. 2000. Treatment of acute tonsillitis with a xed-combination herbal
preparation. Advanced Therapy: 17(4): 197-203.
Tsuchiya H. 2001. Biphasic membrane effects of capsaicin, an active
component in Capsicum species. Journal of Ethnopharmacology
75(2-3): 295-299.
Yoshioka M., et al. 2001. Combined effects of red pepper and caffeine
consumption on 24 h energy balance in subjects given free access to
foods. Br J Nutr 85(2): 203-211.
Page 43
GF

Cyruta
Made From Buckwheat, Containing Powerful Antioxidants

Buckwheat (Fagopyrum esculentum) is typically thought of as a food. Even
though the seeds are used as cereal, the plant is not one of the cereal grasses but
rather a herbaceous plant. Rich in protein (especially lysine, which is uncommon
in most cereal grains), buckwheat also contains vitamins B and E, calcium, and
phosphorus. Buckwheat is easily digestible. It has more iron, copper, and
magnesium than wheat.
How Cyruta Keeps You Healthy

Buckwheat contains rutin, a powerful antioxidant
Buckwheat contains rutin, a phytochemical of the avonoid group and a
powerful antioxidant. Rutin protects the body against a variety of damaging
oxidative toxins, especially those released by the body from mineral-ber
irritation. By itself, rutin is a more potent free-radical eliminator than either
vitamin C or vitamin E. Synergistically, the three work together to create an
antioxidant powerhouse.
Antioxidants rutin and quercetin help support the skin

Because it is exposed, the skin is particularly vulnerable to environmental
damage, especially from the suns rays. Rutin and quercetin protect the skin and
nerves from oxidative damage.
Soluble ber and rutin found in buckwheat help maintain the cardiovascular system
The soluble ber in buckwheat can help maintain a proper balance between
high- and low-density lipoproteins. Furthermore, rutin prevents the oxidation of
low-density lipoprotein in artery walls. As an antioxidant, rutin also minimizes
oxidative damage in red blood cells, especially to delicate cell walls and to
important fats embedded in those walls, and to essential oxygen-carrying
hemoglobin. Rutin also helps keep blood thin, thus encouraging its free ow
through the circulatory system, primarily in peripheral arterial systems.
Quercetin helps maintain orderly cell growth in breast and other tissues
Quercetin attaches to type-II estrogen-binding sites and helps prevent protein
kinase C activation, a cause of undesirable cell division and growth.
C
y
r
u
t
a
Introduced in 1948
GF
Content:
90 tablets
or as directed.
Supplement Facts:
Serving Size: 1 wafer
Amount
per Serving %DV
Calories 2
Vitamin C 3 mg 4%
Dried buckwheat (leaf) juice, buckwheat (seed),
inositol, oat our, and bovine adrenal Cytosol
extract.
Each tablet supplies approximately:
245 mg buckwheat leaf juice and seed and
80 mg inositol.
Other Ingredients: Honey, ascorbic acid, and
calcium stearate.
Page 44
Cyruta
What Makes Cyruta Unique

Product Attributes
Each tablet supplies 245 mg buckwheat leaf juice and seed
Contains 80 mg of inositol to maintain capillary health

promptly processed
The nutrients in Cyruta are processed to remain intact, complete
nished products
supplement facts for Cyruta
.
Affany A., Salvayre R., Douste-Blazy L. 1987. Comparison of the Protective
Effect of Various Flavonoids Against Lipid Peroxidation of Erythrocyte
Membranes (induced by cumene hydroperoxide). Fundam Clin Pharmacol
1(6): 451-457.
Belcaro G., Errichi B.M., et al. 1989. Treatment of acute supercial
thrombosis and follow up by computerized thermography. Vasa 18(3):
227-234.
Belcaro G., Rulo A., Candiani C. 1989. Evaluation of the microcirculatory
effects of Venoruton in patients with chronic venous hypertension by
Laserdoppler owmetry, transcutaneous PO2 and PCO2 measurements,
leg volumetry and ambulatory venous pressure measurements. Vasa
18(2): 146-151.
Bijlani R.L., Sud S., Sahi A., et al. 1985. Effect of Sieved Buckwheat
(Fagopyrum esculentum) Flour Supplementation on Lipid Prole and
Glucose Tolerance. Indian J Physiol Pharmacol 29(2): 69-74.
Cappelli R., Pecchi S., et al. 1987. Efcacy of O-(?-Hydroxyethyl)-
Rutosides at High Dosage in Counteracting the unwanted activity of
Oral Contraceptives on Venous Function. Int J Clin Pharmacol Res 7(4):
291-299.
de Francischi M.L., Salgado J.M., Leitao R.F. 1994. Chemical, nutritional
and technological characteristics of buckwheat and non-prolamine
buckwheat ours in comparison of wheat our. Plant Foods Hum Nutr
46(4): 323-329.
Ekestrom S., Sonnenfeld T., Lund F. 1984. The Effect of O-(?-Hydroxyethyl)-
Rutosides on Central Haemodynamics During and After Aortocoronary
Bypass Surgery. Scand J Thorac Cardiovasc Surg 18(3): 255-258.
Grinberg L.N., Rachmilewitz E.A., Newmark H. 1994. Protective Effects
of Rutin Against Hemoglobin Oxidation. Biochem Pharmacol 48(4):
643-649.
He J., Klag M.J., Whelton P.K., et al. 1995. Oats and buckwheat intakes and
cardiovascular disease risk factors in an ethnic minority of China.
Am J Clin Nutr 61(2): 366-372.
Jelnes R., Gaardsting O., Holm A. 1986. Improvement of Subcutaneous
Nutritional Blood Flow in the Forefoot by Hydroxyethylrutosides in Patients
with Arterial Insufciency: Case Studies. Angiology 37(3 Pt 1): 198-202.
Korkina L.G., Durnev A.D., et al. 1992. Oxygen radical-mediated mutagenic
effect of asbestos on human lymphocytes: suppression by oxygen radical
scavengers. Mutat Res 265(2): 245-253.
Mistry K.J., Krishna M., Bhattacharya R.K. 1997. Modulation of Aatoxin
B1 Activated Protein Kinase C by Phenolic Compounds. Cancer Lett
121(1): 99-104.
Moser M., Ranacher G., Wilmot T.J., et al. 1984. A Double-Blind Clinical
Trial of Hydroxyethylrutosides in Menieres Disease. J Laryngol Otol
98(3): 265-272.
Negre-Salvayre A., Affany A., Hariton C., et al. 1991. Additional
Antilipoperoxidant Activities of Alpha-Tocopherol and Ascorbic Acid
on Membrane-Like Systems Are Potentiated by Rutin. Pharmacology
42(5): 262-272.
Negre-Salvayre A., Mabile L., Delchambre J., et al.. 1995. Tocopherol,
Ascorbic Acid, and Rutin Inhibit Synergistically the Copper-Promoted LDL
Oxidation and the Cytotoxicity of Oxidized LDL to Cultured Endothelial
Cells. Biol Trace Elem Res 47(1-3): 81-94.
Negre-Salvayre A., Salvayre R. 1992. Quercetin Prevents the Cytotoxicity
of Oxidized LDL on Lymphoid Cell Lines. Free Radic Biol Med 12(2):
101-106.
Piantelli M., Maggiano N., et al. 1995. Tamoxifen and Quercetin Interact with
Type II Estrogen Binding Sites and Inhibit the Growth of Human Melanoma
Cells. J Invest Dermatol 105(2): 248-253.
Piller N.B., Morgan R.G., Casley-Smith J.R. 1988. A double-blind, cross-over
trial of o-(?-hydroxyethyl)-rutosides (benzo-pyrones) in the treatment of
lymphoedema of the arms and legs. Br J Plast Surg 41(1): 20-27.
Ranelletti F.O., Ricci R. 1992. Growth-Inhibitory Effect of Quercetin and
Presence of Type-II Estrogen-Binding Sites in Human Colon-Cancer Cell
Lines and Primary Colorectal Tumors. Int J Cancer 50(3): 486-492.
Sadzuka Y., Sugiyama T., et al. 1997. Protective effect of avonoids on
doxorubicin-induced cardiotoxicity. Toxicology Lett 92(1): 1-7.
Saija A., Scalese M., et al. 1995. Flavonoids as Antioxidant Agents:
Importance of their Interaction with Biomembranes. Free Radic Biol Med
19(4): 481-486.
Scambia G., Ranelletti F.O., et al. 1990. Type-II Estrogen Binding Sites in a
Lymphoblastoid Cell Line and Growth-Inhibitory Effect of Estrogen, Anti-
Estrogen and Bioavonoids. Int J Cancer 46(6): 1112-1116.
Shimoi K., Shen B., et al. 1997. Protection by G-Rutin, a Water-soluble
Antioxidant Flavonoid, against Renal Damage in Mice Treated with Ferric
Nitrilotriacetate. Jap Journal of Cancer Res 88(5): 453-460.
Skaper S.D., Fabris M., Ferrari, et al. 1997. Quercetin Protects Cutaneous
Tissue-Associated Cell Types Including Sensory Neurons from Oxidative
Stress Induced by Glutathione Depletion: Cooperative Effects of Ascorbic
Acid. Free Radic Biol Med 22(4): 669-678.
Wojcicki J., Samochowiec L. 1995. Effect of Buckwheat Extract on Free
Radical Generation in Rabbits Administered High-fat Diet. Phytother Res
9(5): 323-326.
Page 45
GF

Biost
A Special Combination Formula That Supports Cellular and

Skeletal Health
Bone serves a myriad of functions beyond providing shape and support for the body.
Bone stores essential mineral salts, while bone marrow provides a manufacturing
plant for the formation of blood cells. Manganese is necessary for bone growth,
development, and replacement. Manganese is involved with the health and
maintenance of ligaments and tendons, as demonstrated in numerous animal
studies. Manganese helps to form cartilage and synovial uid and is required to
synthesize bone. Manganese is also necessary (in small quantities) for protein and fat
metabolism. Manganese supports healthy nerves and strengthens immunity while
also playing a role in blood-sugar regulation and energy production.
How Biost Keeps You Healthy

Maintains cellular health
Protomorphogen extract is the brand name of Standard Process extracts
derived from nucleoprotein-mineral molecules. The foundation for the function
of these uniquely formulated, nucleoprotein-mineral extracts comes from the
antigen-antibody reaction that takes place during normal cell maintenance. The
antigenic properties promote healthy cellular division, function, and growth.
When a tissue needs support, at least a dozen different compounds are formed
that can cause white blood cells to travel together toward the compromised area.
These compounds include degenerative products of the tissues themselves. They
strongly activate the macrophage system, and within a few hours, the
macrophages begin to devour the destroyed tissue byproducts. At times, the
macrophages can also affect the structure of the remaining healthy cells. The veal
bone PMG extract in Biost appears to neutralize the circulating antibodies,
thereby contributing to the maintenance of cellular health.
Supports skeletal health

Manganese acts as a catalyst and a cofactor in many enzymatic processes important
in skeletal and connective-tissue development. Manganese is necessary for
appropriate bone growth and development. Manganese plays a prominent role
among the enzymes necessary for mucopolysaccharide synthesis.
Mucopolysaccharide is an important constituent of the bone and cartilage structural
matrix, as well as in the health and maintenance of ligaments and tendons.
Improves calcium absorption

While many people fail to take in adequate amounts of calcium from their diets,
their calcium intake is further compromised by consuming food or drinks that
inhibit calcium absorption or that contain calcium in a complex state. Calcium
lactate is a very soluble and highly bioavailable calcium salt, changing to calcium
bicarbonate (the type used by the body) in one chemical step. Unlike other
forms of calcium that are largely insoluble in water and need acid conditions in
order to be absorbed, Standard Process calcium lactate is highly soluble in
water (a neutral pH) and does not depend on acidic conditions to function.
B
i
o
s
t

Introduced in 1954
GF
Content:
90 tablets
360 tablets
or as directed.
Supplement Facts:
Amount
per Serving %DV
Calories 1
Manganese 6 mg 300%
Sodium 10 mg <1%
2,000-calorie diet.
Veal bone PMG extract, calcium lactate, and
magnesium citrate.
Other Ingredients: Manganese lactate, honey,
cellulose, and calcium stearate.
Each tablet supplies approximately:
170 mg veal bone PMG extract.
Page 46
Biost
What Makes Biost Unique

Product Attributes
Contains a unique blend of ingredients for a variety of nutritional benets
Veal bone PMG
extract contains bone tissue and bone marrow, providing

natural support for the healthy formation of red blood cells
extracts
Standard Process uses a unique manufacturing method of deriving tissue cell
determinants from animal glands and organs
Help provide cellular support and rehabilitation to the corresponding
human tissues
The calcium lactate in Biost is a pure-vegetable source of calcium

Not derived from a dairy source
The nutrients in Biost are processed to remain intact, complete nutritional
compounds
nished products
supplement facts for Biost
.
Dictionary. 5th ed. Mosby: St. Louis. 213, 985.
Aschner M., et al. Manganese uptake and distribution in the central nervous
system. Neurotoxicology. Apr-Jun 1999; 20(2-3): 173-180.
Balch J.F., Balch P.A. 1997. Prescription for Nutritional Healing. 2nd ed.
Avery Publishing Group: Garden City Park. 26-27.
Carter S.D., et al. Effects of porcine somatotropin on calcium and
phosphorus balance and markers of bone metabolism in nishing pigs.
Journal of Animal Science. Aug 1999; 77(8): 2163-2171.
Dale L., Jones C.M. BMP signaling in early Xenopus development.
Bioessays. Sep 1999; 21(9): 751-760.
Fechter L.D. Distribution of manganese in development. Neurotoxicology.
Apr-Jun 1999; 20(2-3): 197-201.
Finley J.W. Manganese absorption and retention by young women is
associated with serum ferritin concentration. American Journal of
Clinical Nutrition. Jul 1999; 70(1): 37-43.
Geesink R.G., et al. Osteogenic activity of OP-1 bone morphogenetic protein
(BMP-7) in a human bular defect. British Journal of Bone and Joint
Surgery. Jul 1999; 81(4): 710-718.
Gong H., Amemiya T. Corneal changes in manganese-decient rats.
Cornea. Jul 1999; 18(4): 472-482.
Goud S.N. Effects of sublethal radiation on bone marrow cells: induction of
apoptosis and inhibition of antibody formation. Toxicology. Jul 15 1999;
135(2-3): 69-76.
Greger J.L. Nutrition versus toxicology of manganese in humans: evaluation
of potential biomarkers. Neurotoxicology. Apr-Jun 1999; 20(2-3):
205-212.
Guyton A.C., Hall J.E. Genetic Control of Protein Synthesis, Cell Function, and
Cell Reproduction. Textbook of Medical Physiology. 37
Guyton A.C., Hall J.E. Inammation and function of macrophages. Textbook
of Medical Physiology. 9th ed. 439.
Guyton A.C., Hall J.E. White blood cells and chemotactic attraction.
Textbook of Medical Physiology. 9th ed. 434.
Keen C.L., et al. Nutritional aspects of manganese from experimental
studies. Neurotoxicology. Apr-Jun 1999; 20(2-3): 213-223.
Kiningham K.K., et al. Overexpression of manganese superoxide dismutase
protects against mitochondrial-initiated poly (ADP-ribose) polymerase-
mediated cell death. FASEB J. Sep 1999; 13(12): 1601-1610.
Lai J.C., et al. Manganese mineral interactions in brain. Neurotoxicology.
Apr-Jun 1999; 20(2-3): 433-444.
Leibovitz B. 1991. Nutrition Update. 5(2).
Mori T., et al. Substance P Regulates the Function of Rabbit Cultured
Osteoclast; Increase of Intracellular Free Calcium Concentration and
Enhancement of Bone Resorption. Biochemical Biophysical Research
Communication. Aug 27 1999; 262(2): 418-422.
Pfeiffer C.C. 1978. Zinc and Other Micronutrients. 66.
Sziraki I., et al. Implications for atypical antioxidative properties of manganese
in iron-induced brain lipid peroxidation and copper-decient low density
lipoprotein conjugation. Neurotoxicology. Apr-Jun 1999; 20(2-3):
455-66.
Taal M.W., et al. Risk factors for reduced bone density in haemodialysis
patients. Nephrol Dial Transplant. Aug 1999; 14(8): 1922-1928.
Tabers Cyclopedic Medical Dictionary. 18th ed. 1997. 248.
van Mossevelde B. Culinary Cures: Calcium Fortication. Food Product
Design. Sept 1997. 69-70.
Page 47
GF


Introduced in 1934
GF

V
Content:
90 tablets
Suggested Use: One tablet per day,
or as directed.
Supplement Facts:
Amount
per Serving %DV
Calories 1
Vitamin D 800 IU 200%
Calcium 20 mg 2%
Ingredients: Calcium lactate, milk powder,
potassium citrate, glycerin, calcium stearate,
arabic gum, starch, sucrose (beets), vitamin A
palmitate, cholecalciferol, and ascorbic acid.
Cataplex

D
Supports Bone Tissue and Increases Bioavailability of Calcium
The vitamin D complex found in Cataplex D supplies essential nutrients for
maintaining healthy bones, muscle, teeth, and epithelial tissue. Vitamin D plays
an important role in cell replication and tissue formation and helps maintain a
healthy immune system. The vitamin D in Cataplex D increases the availability
and absorption of calcium by all tissues. Vitamin D also helps control blood
levels of calcium and phosphate, which work together at the cellular level to
supply energy and the materials for growth and repair. Calcium also plays a
signicant role in the growth process, inuencing reproductive health and
keeping bones and teeth at the appropriate density for proper growth and
maintenance. Vitamin A is essential to the normal growth process and is also
supportive of reproductive health.
How Cataplex D Keeps You Healthy

Builds strong bones and teeth
Vitamin D maintains calcium and phosphate levels to ensure correct
mineralization of bones. Vitamin D also plays a role in calcium absorption.
Vitamin D requires several other nutrients for assimilation, including the
calcium and the vitamin A present in Cataplex D. The human body contains
more calcium than any other mineral. Almost 90 percent of that calcium is used
in the bones and teeth.
Supports normal growth and reproductive health

Vitamin A is essential to the synthesis of ribonucleic acid (RNA) in its role in the
normal growth process. Vitamin A also supports reproductive health by
participating in both RNA and protein synthesis. Vitamin A helps support
healthy sperm in males and helps support healthy pregnancy in females. Calcium
works with phosphorus at the cellular level, reacting with proteins, fats, and
carbohydrates to supply energy and the materials for proper growth and repair
of cells.
Promotes healthy immune function

Vitamin D is recognized as fundamental to the development and control of
important cells in the immune system, including lymphocytes and macrophages.
Vitamin D acts on immune cells, producing a variety of chemical messengers.
Adequate levels of vitamin D are required in these processes to maintain the
integrity of the immune system.
C
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Page 48
Cataplex

D
What Makes Cataplex D Unique
Product Attributes
Contains cholecalciferol (vitamin D
3
)
The most important naturally occurring form of vitamin D
nished products
supplement facts for Cataplex
D.
Balch J.F. 1997. Prescription for Nutritional Healing: A Practical A to Z
Reference to Drug-free Remedies Using Vitamins, Minerals, Herbs
& Food Supplements. 6-9, 18-21.
Barger-Lux M.J., Heaney R.P. 1994. The role of calcium intake in preventing
bone fragility, hypertension, and certain cancers. Nutrition Journal
124(8Suppl): 1406S-1411S.
Berdanier C.D. 1995. Advanced Nutrition Micronutrients. Boca Raton, FL:
CRC Press Inc: 22-37.
Blythe S. Dietary Calcium to Prevent Osteoporosis. Brevard Health. Online
Compston J.E. 1998. Vitamin D deciency: time for action. BMJ 37(28):
1466-1467.
Davies P.S., Bates C.J., et al. 1999. Vitamin D: seasonal and regional
differences in preschool children in Great Britain. Eur J Clin Nut 53,
195-198.
Health tips. How to make sure you get enough vitamin D. Mayo Clin Health
Lett 1998: 16(11): 3.
Mawer E.B. 1997. Vitamin D Deciency in Patients with Intestinal
Malabsorption. Nutrition 13: 814-824.
Rock C.L., Thronquist M.D., et al. 1998. Demographic, Dietary and Lifestyle
Factors Differentially Explain Variability in Serum Carotenoids and Fat-
Soluble Vitamins: Baseline Results from the Sentinel Site of the Olestra
Post-Marketing Surveillance Study. Am Soc Nutr Sciences 855-864.
Scheider W.L. 1983. Nutrition, Basic Concepts and Applications. New
York, NY: McGraw-Hill Book Company: 199-200.
7th ed. Philadelphia, PA: Lea & Febiger: 292-310.
Sowers M.F., Lachance L. 1999. Vitamins and Arthritis. Rheum Dis Clin
NA 25(2): 315-331.
Waiters B., Godel J. 1998. Perinatal Vitamin D and Calcium Status of
Northern Canadian Mothers and Their Newborn Infants. J Am Coll Nut
18(1): 122-126.
West-Suitor C.J., Forbes-Crowley M. 1984. Nutrition, Principles and
Application in Health Promotion. 2nd ed. Philadelphia, PA: J.B.
Lippincott Company: 42-43.
Whiteld J.F. 1990. Calcium, Cell Cycles, and Cancer. Boca Raton, FL:
CRC Press Inc: 7-32.
Page 49
Gotu Kola Complex: Tissue Support Formula
Gotu Kola Complex is a unique combination of Gotu Kola herb and
concentrated extracts of Grape Seed and Ginkgo leaf that supports the
normal tissue repair process.*
Clinical trials suggest that to be effective Gotu Kola and Grape Seed
extract should contain substantial levels of the important plant
constituents: triterpenes and procyanidins respectively.
1,2
Standardized
Ginkgo extract, containing 24% ginkgo avonglycosides (ginkgo avone
glycosides) has been also extensively investigated in clinical trials.
2

Standardized means the extracts must contain a certain amount of
important constituents.*
Healthy tissues
Connective tissue gets its name because of its function: it connects other
tissues and body systems. Collagen and elastin are important components
of connective tissues. The normal processes of tissue repair are mostly
a function of connective tissues.
3,4
Another type of tissue is epithelial
tissue. The outer layer of skin is epithelial tissue; beneath this is the
dermis made of connective tissue. Because blood vessels do not occur in
epithelial tissues, the connective tissue layer is essential so the epithelial
cells can receive nutrients from the blood vessels in the connective tissue
beneath.
3
*
How Gotu Kola Complex Keeps You Healthy
Promotes healthy tissues, supports capillary integrity and the
bodys normal tissue repair process
The triterpenes of Gotu Kola have been used clinically to support the
normal repair process of skin.
5,6
Gotu Kola has been used traditionally
to help maintain healthy tissue uid levels during the normal repair
processes of skin, muscles and cartilage.
7
*
Capillaries are very small blood vessels that are in close contact with the
surrounding tissues. The uids that nourish these tissues, the wastes that
are excreted, the oxygen, water and food that are absorbed all enter and
leave via the capillaries.
3
In mostly uncontrolled clinical trials, standardized
Grape Seed extract promoted healthy blood vessel walls and healthy
capillaries. This helped prevent leakage of uid from the capillaries to
the surrounding body tissues.
8-12
These activities have also been shown
clinically for the triterpenes of Gotu Kola.
1,13,14
The results from one trial
suggest that the triterpenes of Gotu Kola provide benet by helping
maintain normal, healthy connective tissue in the walls of veins.
13
*
Supplement Facts
Calories 3
Calcium 70 mg 7%
Gotu Kola herb 10:1 extract 250 mg

from Centella asiatica herb 2.5 g
Containing triterpenes 50 mg
Grape seed 120:1 extract 30 mg

from Vitis vinifera seed 3.6 g

Containing procyanidins 25.5 mg
Ginkgo leaf 50:1 extract 20 mg

from Ginkgo biloba leaf 1.0 g

Containing ginkgo avonglycosides 4.8 mg

Containing ginkgolides & bilobalide 1.2 mg

Other ingredients: Calcium acid phosphate, cellulose, sodium starch glycollate,
magnesium stearate and hypromellose.
Caution: Contraindicated in known allergy to Gotu Kola. Not to be used during
pregnancy and lactation unless otherwise directed by a qualied health care
professional.
Product No Content
M1313 40 Tablets
Gotu Kola Complex
M1313
G
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K
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Page 50
knowledge.
standards.
www.mediherb.com
Experiments in test tubes are often conducted to learn more about how herbal extracts work
in the body. These tests suggest that the triterpenes of Gotu Kola support existing collagen and
promote the normal synthesis of collagen in the skin and vein wall.
1,15
These triterpenes also
support the epithelial cells in the inner layer of veins.
1
The procyanidins of Grape Seed also
support existing collagen and elastin within vein walls.
2
*
Gotu Kola is recommended traditionally to support healthy stomach and duodenal tissue.
16
The
benet of this traditional use has also been shown in uncontrolled trials using the triterpenes of
Gotu Kola.
17
*
Supports healthy circulation
In a controlled clinical trial, standardized Ginkgo extract enhanced healthy blood ow in the
capillaries of the ngers.
18
Enhanced circulation is an important factor in supporting the healing
process in tissues throughout the body. Healthy circulation provides the tissues with oxygen,
nutrients and the substances used by the body in the normal repair process.*
What Makes Gotu Kola Complex Unique
Gotu Kola Complex is unique in the professional herbal products industry because:
(ginkgo avonglycosides, ginkgolides, bilobalide)

triterpenes in Gotu Kola

procyanidins in Grape Seed extract

ginkgo avonglycosides (quercetin, kaempferol, isorhamnetin) in Ginkgo

MediHerbs testing also ensures the triterpenes are retained in the product throughout
manufacture

References
1
Incandela L, Cesarone MR, Cacchio M et al. Angiology 2001; 52(Suppl 2): S9-S13
2
McKenna DJ, Jones K, Hughes K et al. Botanical Medicines: The Desk Reference for Major Herbal Supplements, 2nd Edn. New York, Haworth
Herbal Press, 2002.
3
4
Wheater PR, Burkitt HG, Daniels VG. Functional Histology: A Text and Colour Atlas. Churchill Livingstone, Edinburgh, 1979.
5
Bosse JP, Papillon J, Frenette G et al. Ann Plast Surg 1979; 3(1): 13-21
6
Huriez CL, Martin P. Lille Med 1972; 44(9): 463-464
7
Pharmacopoeia Commission of the Peoples Republic of China. Pharmacopoeia of the Peoples Republic of China, English Edn. Chemical Industry
Press, Beijing, 1997.
8
Dubos G, Durst G, Hugonet R et al. Rev Geriatrie 1980; 5(6): 302-305
9
Dartenuc JY, Marache P, Choussat H. Bordeaux Med 1980; 13(18): 903-907
10
Costantini A, De Bernardi T, Gotti A. Minerva Cardioangiol 1999; 47(1-2): 39-46
11
Vrin Ph, Vildy A, Maurin JF. Bordeaux Med 1978; 11(16): 1467
12
Fromantin M. Med Intern 1981; 16(11): 432-434
13
Arpaia MR, Ferrone R, Amitrano M et al. Int J Clin Pharmacol Res 1990; 10(4): 229-233
14
Montecchio GP, Samaden A, Carbone S et al. Haematologica 1991; 76(3): 256-259
15
Brinkhaus B, Lindner M, Schuppan D et al. Phytomedicine 2000; 7(5): 427-448
16
Noumi E, Dibakto TW. Fitoterapia 2000; 71(4): 406-412
17
World Health Organization. WHO Monographs on Selected Medicinal Plants, Vol 1. WHO, Geneva, 1999.
18
Jung F, Mrowietz C, Kiesewetter H et al. Arzneim Forsch 1990; 40(5): 589-593

Page 51
Bone Complex: Flavonoids for Structural Support
Bone Complex is a unique combination of Epimedium aerial parts, Kudzu
root, Red Clover owering tops and Black Cohosh root. Three of these
herbs contain avonoids which may support healthy bones. Flavonoids
are a large group of naturally occurring compounds (many are found
in foods), and are classied by structure into several groups including
avonols and isoavones.*
Bone: structure & function
Connective tissue protects and supports the body and its organs. Bone is
one type of connective tissue. The functions of bones include support
(eg posture), protection (eg of the brain, spinal cord), motion, mineral
storage (mostly calcium and phosphate), energy storage (eg fat-rich
yellow marrow) and production of blood cells (occurs in the red marrow).
Bone is a tissue that is constantly changing. Like other connective
tissue, bone is made up of collagen, but unlike other connective tissue
it also contains a lot of calcium salts, mainly calcium phosphate. The
combination of collagen and calcium phosphate makes bones strong
yet exible. Some bones grow for your entire life, others stop growing
(in length) in your twenties. Bones are not uniformly solid and they are
made up of many parts. Several of these parts, including the periosteum,
a thin membrane covering the outside of the bone, contain the cells
necessary for the growth and repair of bone.
1-3
*
Healthy bones: breaking down & building up
Bones cannot grow continually. As the width of a bone increases, the
marrow cavity needs to remain the same size relative to the length of
the bone, so some of the cells in the walls of the cavity are destroyed. In
addition to this, the bodys tissues need a certain amount of calcium
(eg for muscle contraction, nerve conduction), so the matrix part of
the bone is broken down (to release calcium). The matrix can also be
rebuilt to deposit calcium. This breaking down and rebuilding is called
remodeling. As well as allowing the body to store calcium, remodeling
allows worn or stressed bone to be removed and replaced with new
bone tissue.
1,2
*
The cells responsible for bone growth are called osteoblasts
(osteo = bone, blast = bud). Osteoclasts are the cells responsible for the
breakdown (osteo = bone, clast = break) and removal (called resorption)
of bone tissue.
1,2
*
Normal bone growth in children and adolescents, and replacement
of bone tissue in adults depend on several factors including sufcient
quantities of calcium and phosphorus in the diet, sufcient vitamins
A, C and D and the manufacture of the proper amounts of the certain
hormones in the body. Bones respond to stress by increasing osteoblast
activity, leading to an increase in bone formation and/or bone density.
Physical activity is an example of one such stress: a physically active
person doing weight-bearing exercise can build stronger bones.
1,2
*
Supplement Facts
Calories 3
Calcium 40 mg 4%
Epimedium herb top 12:1 extract 200 mg
from Epimedium sagittatum herb top 2.4 g

Containing icariin 20 mg
Red Clover herb owering top 5:1 extract 100 mg
from Trifolium pratense herb

owering top 500 mg
Containing isoavones 8 mg
Kudzu root 10:1 extract 70 mg
from Pueraria lobata root 700 mg

Containing puerariae isoavones calculated as
daidzin, puerarin, daidzein 28 mg
Black Cohosh root 4:1 extract 20 mg
from Cimicifuga racemosa root 80 mg

Other ingredients: Cellulose, calcium acid phosphate, sodium starch glycollate,
maltodextrin, hypromellose and magnesium stearate.
Caution: Contraindicated in pregnancy, lactation and in women with estrogen-
dependent tumors such as breast cancer. Caution in patients with liver
problems, who frequently use alcohol or take medications.
Product No Content
M1145 40 Tablets
Bone Complex
M1145
B
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Page 52
knowledge.
standards.
www.mediherb.com
Battle of the bone cells?
After childhood, remodeling usually occurs at a balanced rate: for every bone unit that is broken
down, another is rebuilt. The rate of remodeling varies according to the part of the bone and
the location of the bone. However, at midlife, particularly for women, the osteoblasts become
less active leading to a decrease in bone mass. Other factors that can contribute to a decrease in
bone mass in later years include cigarette smoking, excessive intake of alcohol and use of certain
prescription drugs.
1-3
*
How Bone Complex Keeps You Healthy
Supports bone health
Randomized, double-blind, placebo-controlled clinical trials have found that Black Cohosh and
the avonoids in Epimedium, Kudzu and Red Clover help keep bones strong and healthy.
4-8
This
is particularly the case in mature women, and often in conjunction with weight-bearing exercise
and a healthy diet containing food sources of calcium and vitamin D.*
These avonoids may do this by supporting normal bone remodeling process and optimal repair
of bone tissue that has been damaged as a consequence of normal wear and tear and aging.
Specically, this support may be achieved by rebalancing bone remodeling to have a net positive
effect on bone formation compared to bone resorption.
4,5,7,9
*
What Makes Bone Complex Unique
Bone Complex is unique in the professional herbal products industry because:
(icariin, isoavones of Red Clover and Kudzu)
icariin in Epimedium
isoavones in Red Clover
isoavones in Kudzu (as daidzein, daidzin, puerarin)
MediHerbs testing also ensures the icariin and isoavones are retained in the product
throughout manufacture
Use of the latest and most relevant test methods for the analysis of raw materials and
nished products
References
1
2
Tortora GJ, Anagnostakos NP. Principles of Anatomy and Physiology, 4th Edn. Harper & Row, New York, 1984.
3
U.S. Department of Health and Human Services. Handout on Health: Osteoporosis. NIH Publication No. 07-5158, April 2007. Available online:
http://www.niams.nih.gov/Health_Info/Bone/Osteoporosis/osteoporosis_hoh.pdf. Accessed 8 May 2009.
4
Zhang G, Qin L, Shi Y. J Bone Miner Res 2007; 22(7): 1072-1079
5
Marini H, Minutoli L, Polito F et al. Ann Intern Med 2007; 146(12): 839-847
6
Wu J, Oka J, Tabata I et al. J Bone Miner Res 2006; 21(5): 780-789
7
Atkinson C, Compston JE, Day NE et al. Am J Clin Nutr 2004; 79(2): 326-333
8
Wuttke W, Seidlova-Wuttke D, Gorkow C. Maturitas 2003; 44(Suppl 1): S67-S77
9
Morabito N, Crisafulli A, Vergara C et al. J Bone Miner Res 2002; 17(10): 1904-1912

Page 53

Liver As Endocrine - Stuart White

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Liver As Endocrine - Stuart White

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Dr.

Stuart White July 26, 2012

Contains Many Nutrients, Including Betaine, to Protect the Liver

Provides many essential nutrients to support overall health

What Makes A-F Betafood Unique

Multiple nutrients from a variety of plant and animal sources

Certied Organic Farming

How Choline Keeps You Healthy

Keeps your heart and liver healthy

Maintains cellular health

Manufacturing and Quality-Control Processes

Promotes Healthy Liver, Cardiovascular, and Cellular Function

How Betacol Keeps You Healthy

Supports cardiovascular health

Promotes healthy cellular function

What Makes Betacol Unique

Multiple nutrients from a variety of plant and animal sources

Manufacturing and Quality-Control Processes

extract, Spanish black

extract, defatted wheat (germ),

A Multi Food-Based Formula for the Liver

How Livaplex Keeps You Healthy

Supports the livers natural antioxidant functions

What Makes Livaplex Unique

Certied Organic Farming

is a unique combination of Schisandra berries, concentrated Milk

Keeps You Healthy

Daily Value (DV) not established.

is unique in the professional herbal products industry because:

2011. All rights reserved.

Complex: Sustainable Liver Toning

Complex is a unique combination of concentrated Milk Thistle

Daily Value (DV) not established.

Complex Keeps You Healthy

2007. All rights reserved.

Daily Value (DV) not established.

2011. All rights reserved.

Daily Value (DV) not established.

2011. All rights reserved.

Provides alkaline-based digestive support for the acid-sensitive individual

Manufacturing and Quality-Control Processes

Contains Digestive Enzymes to Support the Proper Breakdown

How Multizyme Keeps You Healthy

What Makes Multizyme Unique

Manufacturing and Quality-Control Processes

How Collinsonia Root Keeps You Healthy

Promotes digestive efciency

Helps maintain heart and lung health

Helps maintain a healthy urinary system

Contains Organically Grown, Minimally Processed

Provides antioxidant support

What Makes Cruciferous Complete Unique

Daily Value (DV) not established.

2012. All rights reserved.

How Cayenne Pepper Keeps You Healthy

Maintains healthy circulation

Enhances metabolic efciency

Strengthens the immune system

Enhances the efcacy of other herbal and nutritional supplements

Made From Buckwheat, Containing Powerful Antioxidants

How Cyruta Keeps You Healthy

Antioxidants rutin and quercetin help support the skin