10 Things to Hate About Sleep Loss

By Camille Peri Reviewed byJames Beckerman, MD, FACC You know lack of sleep can make you grumpy and foggy. You may not know what it can do to your sex life, memory, health, looks, and even ability to lose weight. Here are 10 surprising -- and serious -- effects of sleep loss.

1. Sleepiness Causes Accidents

Sleep deprivation was a factor in some of the biggest disasters in recent history: the 1979 nuclear accident at Three Mile Island, the massive Exxon Valdez oil spill, the 1986 nuclear meltdown at Chernobyl, and others. But sleep loss is also a big public safety hazard every day on the road. Drowsiness can slow reaction time as much as driving drunk. The National Highway Traffic Safety Administration estimates that fatigue is a cause in 100,000 auto crashes and 1,550 crash-related deaths a year in the U.S. The problem is greatest among people under 25 years old. Studies show that sleep loss and poor-quality sleep also lead to accidents and injuries on the job. In one study, workers who complained about excessive daytime sleepiness had significantly more work accidents, particularly repeated work accidents. They also had more sick days per accident.

2. Sleep Loss Dumbs You Down

Sleep plays a critical role in thinking and learning. Lack of sleep hurts these cognitive processes in many ways. First, it impairs attention, alertness, concentration, reasoning, and problem solving. This makes it more difficult to learn efficiently. Second, during the night, various sleep cycles play a role in consolidating memories in the mind. If you dont get enough sleep, you wont be able to remember what you learned and experienced during the day.

3. Sleep Deprivation Can Lead to Serious Health Problems

Sleep disorders and chronic sleep loss can put you at risk for: Heart disease Heart attack Heart failure Irregular heartbeat High blood pressure Stroke Diabetes According to some estimates, 90% of people with insomnia -- a sleep disorder characterized by trouble falling and staying asleep -- also have another health condition. Increase Stroke Risk Even without the typical risk factors, like being overweight or having a family history, short sleep can up your risk for stroke, according to 2012 research. Adults who regularly slept fewer than six hours a night had four times the risk of stroke symptoms, ...Up Diabetes Risk A pair of small studies from 2012 examined the link between poor sleep and insulin resistance, a telltale risk factor for diabetes. One found that among healthy teenagers, the shortest sleepers had the highest insulin resistance, meaning the body is not using insulin effectively, according to the National Institute of Diabetes and Digestive and Kidney Diseases. The second study examined fat cells, in particular, and found that cutting back on sleep increased insulin resistance in these cells, even when diet and calorie intake were restricted, Health.com reported. You Can't Shake That Cold If you keep coming down with the sniffles -- or can't seem to kick that never-ending case -- you might want to assess your sleep schedule. A 2009 study found that people who sleep fewer than seven hours each night have almost three times the risk of catching a cold than people who slept for at least eight hours, the LA Times reported.

4. Lack of Sleep Kills Sex Drive

Sleep specialists say that sleep-deprived men and women report lower libidos and less interest in sex. Depleted energy, sleepiness, and increased tension may be largely to blame. For men with sleep apnea, a respiratory problem that interrupts sleep, there may be another factor in the sexual slump. A study published in the Journal of Clinical Endocrinology & Metabolism in 2002 suggests that many men with sleep apnea also have low testosterone levels. In the study, nearly half of the men who suffered from severe sleep apnea also secreted abnormally low levels of testosterone during the night.

10 Things to Hate About Sleep Loss

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5. Sleepiness Is Depressing
Over time, lack of sleep and sleep disorders can contribute to the symptoms of depression. In a 2005 Sleep in America poll, people who were diagnosed with depression or anxiety were more likely to sleep less than six hours at night. The most common sleep disorder, insomnia, has the strongest link to depression. In a 2007 study of 10,000 people, those with insomnia were five times as likely to develop depression as those without. In fact, insomnia is often one of the first symptoms of depression. Insomnia and depression feed on each other. Sleep loss often aggravates the symptoms of depression, and depression can make it more difficult to fall asleep. On the positive side, treating sleep problems can help depression and its symptoms, and vice versa.

6. Lack of Sleep Ages Your Skin

Most people have experienced sallow skin and puffy eyes after a few nights of missed sleep. But it turns out that chronic sleep loss can lead to lackluster skin, fine lines, and dark circles under the eyes. When you dont get enough sleep, your body releases more of the stress hormone cortisol. In excess amounts, cortisol can break down skin collagen, the protein that keeps skin smooth and elastic. Sleep loss also causes the body to release too little human growth hormone. When were young, human growth hormone promotes growth. As we age, it helps increase muscle mass, thicken skin, and strengthen bones. Its during deep sleep -- what we call slow-wave sleep -- that growth hormone is released, says sleep expert Phil Gehrman, PhD. It seems to be part of normal tissue repair -- patching the wear and tear of the day.

7. Sleepiness Makes You Forgetful

Trying to keep your memory sharp? Try getting plenty of sleep. In 2009, American and French researchers determined that brain events called sharp wave ripples are responsible for consolidating memory. The ripples also transfer learned information from the hippocampus to the neocortex of the brain, where long-term memories are stored. Sharp wave ripples occur mostly during the deepest levels of sleep. ...Fuel Memory Loss You probably know that on the days when you are most tired, you're forgetful and unfocused -- but sleep deprivation can lead to permanent cognitive issues. The less we sleep, the less we benefit from the memory-storing properties of sleep. But additionally, a lack of sleep can cause "brain deterioration," according to a 2013 study, which may at least in part explain memory loss in seniors.

8. Losing Sleep Can Make You Gain Weight

When it comes to body weight, it may be that if you snooze, you lose. Lack of sleep seems to be related to an increase in hunger and appetite, and possibly to obesity. According to a 2004 study, people who sleep less than six hours a day were almost 30 percent more likely to become obese than those who slept seven to nine hours.

Recent research has focused on the link between sleep and the peptides that regulate appetite. Ghrelin stimulates hunger and leptin signals satiety to the brain and suppresses appetite, says Siebern. Shortened sleep time is associated with decreases in leptin and elevations in ghrelin. Not only does sleep loss appear to stimulate appetite. It also stimulates cravings for high-fat, high-carbohydrate foods. Ongoing studies are considering whether adequate sleep should be a standard part of weight loss programs. ...Lead To Obesity Too little sleep can spur some less-than-ideal food choices, including serving yourself larger portions, and a hankering for junk food, thanks to some complicated hormonal changes that occur when you don't get sufficient shuteye. It seems that six hours of sleep or less bumps up production of the hunger hormone ghrelin and limits leptin, which helps you balance your food intake, according to a 2012 review of 18 studies of sleep and appetite.

9. Lack of Sleep May Increase Risk of Death

In the Whitehall II Study, British researchers looked at how sleep patterns affected the mortality of more than 10,000 British civil servants over two decades. The results, published in 2007, showed that those who had cut their sleep from seven to five hours or fewer a night nearly doubled their risk of death from all causes. In particular, lack of sleep doubled the risk of death from cardiovascular disease. ...Kill You It's not just heart problems that can lead to sleep-deprivation-related death. In fact, short sleepers seem to die younger of any cause than people who sleep about 6.5 to 7.5 hours a night, TIME reported. A 2010 study examined the impact of short sleep on mortality and found that men who slept for less than six hours of sleep a night were four times more likely to die over a 14-year period. The study's authors called this link "a risk that has been underestimated."

10. Sleep Loss Impairs Judgment, Especially About Sleep

Lack of sleep can affect our interpretation of events. This hurts our ability to make sound judgments because we may not assess situations accurately and act on them wisely. Sleep-deprived people seem to be especially prone to poor judgment when it comes to assessing what lack of sleep is doing to them. In our increasingly fast-paced world, functioning on less sleep has become a kind of badge of honor. But sleep specialists say if you think youre doing fine on less sleep, youre probably wrong. And if you work in a profession where its important to be able to judge your level of functioning, this can be a big problem. Studies show that over time, people who are getting six hours of sleep, instead of seven or eight, begin to feel that theyve adapted to that sleep deprivation -- theyve gotten used to it, Gehrman says. But if you look at how they actually do on tests of mental alertness and performance, they continue to go downhill. So theres a point in sleep deprivation when we lose touch with how impaired we are.

SOURCES: Lavie, P. Accident Analysis and Prevention, August 1982. Lavie, P. Journal of Clinical Endocrinology & Metabolism; vol 87: pp 3394-3398. Girardeau, G. Nature Neuroscience, October 2009. Ferrie, J. Sleep, December 2007. Van Dongen, H. Sleep, 2003. Harvard Medical School: Sleep, Performance, and Public Safety, Sleep, Learning, and Memory, Sleep and Mood. National Sleep Foundation: Teens and Sleep, ABCs of ZZZZs -- When you Can't Sleep, "2005 Adult Sleep Habits and Styles."

NIH National Heart, Lung and Blood Institute: Your Guide to Healthy Sleep. Anxiety Disorders Association of America: Sleep Disorders. Allison T. Siebern, PhD,Insomnia and Behavioral Sleep Medicine Program, Stanford University Sleep Medicine Center, Redwood City, Calif. Phil Gehrman, PhD, assistant professor of psychiatry and clinical director, Behavioral Sleep Medicine Program, University of Pennsylvania, Philadelphia. National Highway Traffic Safety Administration: "Research on Drowsy Driving." Reviewed on September 14, 2012 2010 WebMD, LLC. All rights reserved.