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PY TEST SERIES-XI
Duration: 2.00 hours Max Marks: 100

1. 2. 3. 4. 5. 6. 7.

This question paper contains 40 objective type questions. Q. 1 to 40 carry 2 marks each. Q. 41and 50 are common data based question, each carry two marks. In case of wrong answer 0.5 marks will be deducted. Using HP pencil, darken the appropriate double under each digit of your registration number and the letters corresponding to your paper code. Calculator is allowed in the examination hall. charts, graph sheets or tables are NOT allowed in the examination hall Rough work can be done on the question paper itself. Additionally blank pages are given at the end of the question paper for work.

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PY TEST SERIES-XI
1. The US-FDA approved regimen used for two weeks treatment against H. pyroli is (a) Lansoprazole + Amoxicillin + (b) Clarithomycin + Omiprazole Clarithomycin (c) Amoxicillin + Clarithomycin + (d) Amoxicillin + Metronidazole + Bismuth Omeprazole Laxatives modify fluid dynamics and cause fluid accumulation by which of the following mechanism (a) Inhibit Na+K+ATPase of villous cells (b) Enhance PG synthesis in mucosa (c) Stimulate adenyl cyclase in crypt cells (d) All How many grains of glucose are required to make 6 fl. Oz. of 0.4% w/v solution. (a) 2.4 grains (b) 6.24 grains (c) 10.5 grains (d) 24 grains The main pungent substance of ginger is (a) Shogaol (b) Gingerol (c) Zingerone (d) Carotene Which of the following purgative have diphenylmethane moiety (a) Senna (b) Bisacodyl (c) Lactulose (d) Docusates Abietic acid is main constituents of (a) colocynth (b) Lac (c) Storax (d) Colophony Select the drug used to protect ulcer in patients who smoke continuously (a) Carbenoxolone sodium (b) Sucralfate (c) Misoprostol (d) Loxatidine In what proportions should 16%, 8% and 3% alcohol be mixed to get 10% alcohol. (a) 6:6:10 (b) 6:6:6 (c) 2:2:8 (d) 4:6:8 Chelating agent used in wilsons disease to reduce high plasma concentration of free copper is (a) Desferrioxamine (b) Desferiprone (c) Na2EDTA (d) Penicillamine Which of the following statement is uncorrect about Ipecacuanha (a) Pharmacologically active ingredient is (b) Act by irritating gastric mucosa and emetine through CTZ (c) Longer time of action than apomrphine (d) None Steroidal diuretics used to antagonize hypokalemia induced by other diuretics (a) Spironolactone (b) Triamterene (c) Bumetinide (d) Amiloride Live attenuated vaccine of polio virus is given by which of the following route (a) Subcutaneous (b) Oral (c) Intravenous (d) Intramuscular Maximal excretion of sodium in the urine occurs during the following drug therapy (a) Chlorthiazides (b) Acetazolamide (c) Furosemide (d) Chlorthalidone Convert 70% v/v alcohol into proof strength (a) 57.75o O/P (b) 57.75o U/P 2

2.

3. 4. 5. 6. 7. 8. 9. 10.

11. 12. 13. 14.

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15. 16. 17.

18.

19 20. 21. 22. 23. 24. 25. 26. 27.

28.

(c) 22.71o O/P (d) 22.71o U/P The condition of severe deficiency of Niacin is termed as (a) Xerosis (b) Beriberi (c) Pellagra (d) Scurvy Hypersensitive reaction associated with all thiazides diuretics is mainly due to (a) Sulfamoyl moiety (b) Benzothiazide ring (c) Electron withdrawing group (d) a & c Triple antigen combimed vaccine is an antigenic mixture of (a) Tetanus + Diptheria + Pertusis (b) Tetanus + Diptheria + Measels (c) Diptheria + Measels + Pertusis (d) Pertusis + Tetanus + Measels Use of organomercurials as diuretic agent have serious limitation because (a) They are ineffective when the urine is alkaline (b) They are cardio- and nephrotoxic (c) Longer onset of action on parenteral administration (d) All Connecting tubules and cortical collecting tubule is the major site of action of which drug (a) High ceiling diuretics (b) Potassium sparing diuretics (c) Thiazides (d) Carbonic anhydrase inhibitors The drug of choice for lithium induced nephrogenic diabetes insipidus is (a) Desmopressin (b) Chlorpropamide (c) Amiloride (d) Carbamazepine What % strength corresponds to 30% O/P a) 60.26% v/v (b) 70.16% v/v (c) 65.46% v/v (d) 75.48% v/v Recommended intravenous rehydration solution used to manage diarrhoea is mixture of (a) NaCl + KCL +NaHCO3 + Glucose (b) NaCl + KCL +NaHCO3 (c) NaCl + KCL + Sodium citrate + Glucose (d) NaCl + KCL + Glucose Which of the following drug is come in the category of triterpenoids (a) Annatto (b) Coleus (c) Taxus (d) Ambergris FAD and FMN are the coenzymes of following vitamins (a) Vit. B1 (b) Vit. B2 (c) Vit. B3 (d) Vit. B5 Which of the following H2 antagonist exhibit antiandrogenic activity (a) Cimetidine (b) Ranitidine (c) Famotidine (d) Loxatidine 1 ounce is equivalent to (a) 28.35 g (b) 30 g (c) 15.432 g (d) 437.5 g Which of the following statement is/are correct about coleus forskohlii. (a) The leave give coleon E and F (b) The root contain coleonol B and C (c) It activate adenylate cyclase (d) All Synthetic prodrug of antidiuretic harmone is (a) Lypressin (b) Terlipressin (c) Desmopressin (d) Vasopressin 3

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29. 30.

31. 32. 33. 34.

35 36.

37. 38. 39.

40.

Which of the following vitamins have antioxidant property (a) Vit. E (b) Vit. D (c) Vit. C (d) a & c Give a working formula for 12 suppositories of boric acid each weighing 4 g and containg 200mg of boric acid (displacement value of boric acid is 1.6) (a) Boric acid 1.5 g, cocoa butter 46.50 (b) Boric acid 2.4 g, cocoa butter 46.50 (c) Boric acid 2.4 g, cocoa butter 47.00 (d) Boric acid 0.5g, cocoa butter 47.50 High magnitude of Na+ ion reabsorption take place at which site of nephron (a) Proximal tubule (b) Distal tubule (c) Collecting duct (d) Ascending limb of henle loop .vaccine is used to induced antibody production against tuberculosis (a) TAB (b) MMR (c) PCEV (d) BCG An example of live attenuated viral vaccine is (a) Rabies (b) Influenza (c) Measles (d) Hepatitis T.S. of certain part of podophyllum shows the presence of epiblema which are strongly thickened, cortex is similar to rhizome but without calcium oxalate crystals, then the certain part is (a) Rhizome (b) Latex (c) Root (d) Stem o Convert 50 C into F and R scales a) 40oF and 58oR (b) 48oF and 60oR o o (c) 58 F and 40 R (d) 60oF and 48oR Which of the following 5- aminosalicylic acid is used as disease modifying drug in rheumatoid arthritis (a) Sulfasalazine (b) Olsalazine (b) Mesalazine (d) Balsalazine Select the drug used prophylactically and in symptomatic relif in Acute mountain sickness (a) Spironolactone (b) Mersalyl (c) Theophylline (d) Acetazolamide American yew is a common name of (a) Taxus baccata (b) Taxus Canadensis (c) Taxus Americana (d) Taxus cuspidate What is the working formula for 300ml of an eye wash containg 1% of boric acid is to be dispensed. (F.P. of 1% boric aics = -0.29oC and F.P. of 1% solution of sodium chloride = -.58oC) (a) Boric acid 3g, NaCl - 0.39 g (b) Boric acid 3g, NaCl 1.02 g (c) Boric acid 1g, NaCl - 0.78 g (d) Boric acid 2g, NaCl 1.56 g Podophyllotoxin is teranhydronapthalene derivative with OH and lactone group in cis position which are essential for (a) Antimitotic activity (b) Purgative activity (c) Anti-inflammatory activity (d) Nephroprotective activity DATA FOR 41-42 If the adult dose of a ephedrine hydrochloride is 50 mg. What will be the dose for a nine month old infant (a) 1.5 mg (b) 3.0 mg (c) 4.5 mg (d) 6. 25 mg What will be the dose for a child of 4 years old (a) 6.25 mg (b) 12.50 mg 4

41. 42.
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(c)

13.50 mg

(d)

14.0 mg

43. 44.

45.

DATA FOR 43-44 Saffron contains crocin, crocetin, picrocrocin and trace of volatile oil. The bitter principle of saffron is (a) Crocin (b) Crocetin (c) Picrocrocin (d) Volatile oil The hydrolytic product of above chemical constituent is (a) Crocetin + gentibiose (b) Glucose + safranal (c) Crocetin + safranal (d) Picrocrocin + gentibiose LINKED QUESTION Gastric hurrying agent which is widely used as antiemetic is (a) Haloperidol (b) Metoclopramide (c) Ondansentron (d) Cannabinoids The Gastric hurrying effect of above drug is mainly by (a) Blocking dopaminergic receptor (b) Stimulate serotonergic receptor (c) a&b (d) Block histamine receptor LINKED QUESTION Which of the following gastric acid neutralizing drug given systemically in ulcer treatment (a) MgOH (b) CaCO3 (c) NaHCO3 (d) Al(OH)3 gel Use of the above drug is restricted because of its (a) Hepatotoxicity (b) Constipation (c) Nephrotoxicity (d) Cardiotoxicity DATA FOR 49-50 A drug gives violet colour with acetic anhydride and concentrated sulphuric acid. The drug is (a) Capsicum (b) Podophyllum (c) Asafoetida (d) Turmeric When the above test is observed under ultraviolet light, a fluorescence is seen which is (a) Yellow in color (b) Blue in color (c) Red in color (d) Green in color

46.

47. 48.

49. 50.

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