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CHAPTER 30 EVOLUTION
1.
(a)
(b)
Malaria is caused by a parasite that attacks red blood cells. The allele for
normal haemoglobin in red cells is HbA. People with the HbA allele are highly
susceptible to malaria.
In West African countries about 20% of people are heterozygous for a
different allele, HbC. People who are homozygous for HbC suffer from mild
anaemia; however, they rarely suffer from malaria.
Malaria is very common in West Africa, where the HbC allele is increasing in
frequency. Suggest an explanation for this.
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Total 6 marks
2.
(a)
(b)
Explain how geographical isolation can lead to the formation of new species.
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Total 7 marks
3.
Warfarin is a pesticide which inhibits blood clotting. Some rats have the allele WR
which gives them resistance to warfarin. Rats have three possible genotypes:
WRWR
Resistant to warfarin
WRWS
Resistant to warfarin
W W
(a)
Susceptible to warfarin.
(b)
(ii)
(2 marks)
(iii)
Give two assumptions that must be made when using the HardyWeinberg equation.
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Total 9 marks
4.
Huntingtons disease is an inherited condition that affects nerve cells in the brain. It is
caused by a dominant allele. Symptoms do not usually appear until the person is at
least 30 years old. The condition is very rare in most populations. However, in one
isolated population in South America, 48% of the population are heterozygous for the
Huntingtons disease allele.
(a)
(b)
5.
(a)
(b)
Family
Genus
Kingdom
Order
Phylum
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Total 5 marks
TOTAL MARKS FOR EXAM: 34