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1-Propanol
$#' num(er Pu($hem $hem'pider "/!! 4$ num(er "/ num(er 5rug6ank 8499 :e'; $h46! $h4:6< R=4$' num(er #=$ code 6eil tein Reference 9melin Reference +5:et Jmol-+5 image
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Identifiers )1-*+-, 1-+1 1--. 01F*1.20'3 *---).1-0 1*). 56-+1)7 $-70)0 1-Propanol $;46!:*,,+1 $;4:6<1.1,) ";,**7--5-,#>-+ 1-0,*.* *7111 6--,,+ !mage 1 !n$h! Properties $+;,2 1-@1 g molA1 1-@-7)71.,), g molA1 $olorle liCuid ,-+@. mg cmA+ -1*1 D$, 1.) 8, -107 DF 0)-0, D$, +)--+)1 8, *-1-*-, DF
:olecular formula :olar ma 4Bact ma #ppearance 5en ity :elting point 6oiling point
log P 3apor pre ure #cidity (pKa) 6a icity (pK() Refractive indeB (n5) 3i co ity 5ipole moment
-@+*0 1@00 kPa (at *- D$) 11 A* 1@+,) 1@0+, mPa 1@1, 5 Thermochemistry A+-*@)0FA+-*@*0 kJ mol-1 A*@-*171FA*@-*1-1 :J mol-1 10*@, J 8A1 molA1 1.+@01 J 8A1 molA1 Hazards
'td enthalpy of formation EfHo*0, 'td enthalpy of com(u tion EcHo*0, 'tandard molar entropy So*0, 'pecific heat capacity, C
9;' pictogram 9;' ignal ?ord 9;' haGard tatement 9;' precautionary tatement 4" !ndeB 4" cla ification
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R-phra e '-phra e
/FP# )-.
Related compound Propanamine (verify) (?hat i : J K) 4Bcept ?here noted other?i e, data are given for material in their tandard tate (at *7 D$, 1-- kPa)
!nfo(oB reference
1-Propanol i a primary alcohol ?ith the formula $;+$;*$;*2;@ =hi colorle liCuid i al o kno?n a propan-1-ol, 1-propyl!alcohol, n-propyl!alcohol, n-propanol, or imply propanol@ !t i an i omer of i opropanol (*-propanol)@ !t i u ed a a olvent in the pharmaceutical indu try, and for re in and cellulo e e ter @ !t i formed naturally in mall amount during many fermentation proce e @
#hemical!properties
1-Propanol ho? the normal reaction of a primary alcohol@ =hu it can (e converted to alkyl halide L for eBample red pho phoru and iodine produce n-propyl iodide in ,-I yield, ?hile P$l+ ?ith catalytic Mn$l* give 1-chloropropane@ Reaction ?ith acetic acid in the pre ence of an ;*'2. cataly t under Fi cher e terification condition give propyl acetate, ?hile refluBing propanol overnight ?ith formic acid alone can produce propyl formate in 17I yield@ 2Bidation of 1-propanol ?ith /a*$r*2) and ;*'2. give only a +1I yield of propionaldehyde, and therefore for thi type of reaction higher yielding method u ing P$$ or the '?ern oBidation are recommended@ 2Bidation ?ith chromic acid yield propionic acid@
Preparation
1-Propanol i manufactured (y catalytic hydrogenation of propionaldehyde@ =he propionaldehyde i it elf produced via the oBo proce , (y hydroformylation of ethylene u ing car(on monoBide and hydrogen in the pre ence of a cataly t uch a co(alt octacar(onyl or a rhodium compleB@%*& ;*$N$;* H $2 H ;* O $;+$;*$;N2 $;+$;*$;N2 H ;* O $;+$;*$;*2;
# traditional la(oratory preparation of 1-propanol involve treating n-propyl iodide ?ith moi t #g*2@ 1-Propanol ?a di covered in 1,7+ (y $hancel, ?ho o(tained it (y fractional di tillation of fu el oil@ !ndeed 1-propanol i a maPor con tituent of fu el oil, a (y-product formed from certain amino acid ?hen potatoe or grain are fermented to produce ethanol@ =hi proce i no longer a ignificant ource of 1-propanol@
$afety
1-Propanol i thought to (e imilar to ethanol in it effect on human (ody, (ut *-. time more potent@ 2ral <57- in rat i 1,)- mgJkg (compared to )-1- mgJkg for ethanol)@ !t i meta(oliGed into propionic acid@ 4ffect include alcoholic intoBication and high anion gap meta(olic acido i @ # of *-11, only one ca e of lethal 1-propanol poi oning ?a reported@%+&
2-Propanol%!1-&2-'"to(y-1methyletho(y)
#hemical!str"ct"re* =hi tructure i al o availa(le a a *d :ol file@ 0ther!names**-Propanol, 1-(*-(utoBy-1-methoBy)-L5ipropylene glycol, (utyl etherL 5ipropylene glycol n-(utyl etherL 5o?anol 5Pn6L 1-(*(utoBy-1-methylethoBy)propan-*-olL 1-(*-(utoBy-1-methylethoBy)-*propanol