Antidep meds- test 2

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Monamine Oxidase Inhibitors

a vo i d fo o d s w/ tyra mi n e -a g e d /fe rme n te d Avo i d s ti mu l a n ts , n a rc o ti c s , o th e r a n ti d e p re s s a n ts M i s t s to p fo r 14d a ys b 4 s ta rti n g n e w H yp e rte n s i ve c ri s i s

Tricyclic SSRI
SSRI- wellbutrin

dangerous cardiac 4 weeks for full effect can be admin w/ SSRIs common: Elavil, Pamelor, " line"

lower s ide effect better for elderly les s cardio tox. & les s anticoag fas ter than Tri 3- 4 wks til full effect

Don't give w/ w/d, head injury, hx of seizers

usually prescribed w/ antidep, helps insomnia, can be ordered prn, priapism=errection that needs tx intervention

Trazodone SSRI SNRIs

Less sexual dysfunction

paxil, Zoloft, celexa, "tine" "pram" "ene" ome

Serotonin & Norepinephrine Effexor-assess BP

Remeron mirtazepine

Antidep meds- test 2

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Pain syndrome
Option of Effexor
Tri not only heart but also

Cymbalta duloxetine
Pristque desvenlafaxine
1.Severe heart dis eas e 2. Glaucoma 3. Kidney dis eas e 4. *Benign pros tatic hypertrophy* 5. Epileps y

MNzam patch
immediate Mania

MAO <6 can bypass food restrictions >6 cant bypass

Antipsvchotics Li th i u m Ca r b o n a te -p r o to typ e fo r a n ti m a n i c d r u g s Na r r o w to xi xi ty/th e r a p e u ti c...TEACHING ! Ch e m i ca l s tr u ctu r e s i m i l a r to s o d i u m Co m p e te s a t va r i o u s s i te s i n th e b o d y wi th Na h a n d tr e m m o r s , we i g h t g a i n , d u l l n e s s , th yr o i d l a r g a r g y, h e a d a ce n a u s e a , p l o yu n r i n a

Long term mania

Important
Test for toxicity

check bas eline Blood (eletro), Kidneys , als o thyroid, cardiac, Toxicity! Toxicity is increas ed if s odium intake is reduced or los t through fever, s weating, or diarrhea. - 10- 14 days therapeutic

-3-5 d a ys a fte r , 8 -1 2 a fte r d r a wn a fte r l a s t d o s e , s o a m , wa i t to g i ve b 4 b l o o d wo r k. NARRO W l i n e !! 1 .5 -n /v/d / p o l yu r i a , th i r s t, s l i g h t fi n e h a n d tr e m o r s , 1 .5 -2 .0 , co u r s e h a n d tr e m m o r s , co n fu s i o n , m u s cl e h yp e r , G I u p s e t, EKG ch a n g e , l a ck o f co o r d i n a ti o n 2 .0 ve r y s e r i o u s , l a r g e o u t p u t s e i z e r . s e ve r e Hyp o tn

Antidep meds- test 2

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follow up tests
Valproate (Depakote)
skin reaction stevens Johnson syndrome decrease WBC, agranulytoisis
Help w/ alcohol 50% weightloss

renal thyroid 2 major longer effects: hypothyroid, kidney to concentrate urine

Most Bio-polar disorder anticonvulsant s/e GI, increased appetite, sedation, w/g pancitis issue, lab work

Lamatrogene (Lamictal) Biopolar can be Fatal, slow dose increase can prevent n

Tegretol (Carbamaz epine) monitor blood levels 6-12 mcg.

Valproate (Depakote) Therapeutic range: 50- 100 mcg.