Professional Documents
Culture Documents
Cecilia Chi-
Chi-Ham
Directora Ciencia y Tecnología
clchiham@ucdavis.edu
PIPRA, UC Davis
Subscription/fee based
– GenomeQuest www.genomequest.com
– Delphion www.delphion.com
– Others: Westlaw, Lexis, STN, etc.
Geographies
– Countries in which the product will be developed, manufactured,
approved by regulatory agencies, and marketed/sold
Time-frames
– Awareness of 18 month period of periods of silence of US patent
applications
– Patent Maintenance or Life-time (US 17 or 20 years)
– ONGOING analysis to be performed as early in the development phase as
possible.
II. Formular Equipo
Stanton Gelvin, Purdue University
Kan Wang, Iowa State University
SCIENTISTS Pal Maliga, Rutgers University
David Ow, USDA-ARS, UC Berkeley
Brian Miki, Agriculture and Agri-Food Canada
Vibha Srivastava, University of Arkansas
Chris Taylor, Donald Danforth Plant Science Center
Ag-
Ag-Biotech Companies Robert Horsch, Monsanto
Qi Wang, Monsanto
Keith Redenbaugh, Seminis Vegetable Seeds
Regulatory Experts
Kathy Swords, Biotech Business Development, J.R. Simplot Company
Are there blocking patents that could preclude pursuing a new goal?
Based on Public information
C’ PROCESSES
PRETREATMENT SACCHARIF’N FERMENTATION
Chemical Physical CA/PH Enzymes Process Enzymes EEO Process
Genencor USA
Novozymes USA
Dupont USA
Lund University
Hebrew University of Jerusalem
Sweden
Israel
Public
Iogen Energy Corp Canada
Arkenol USA
LIBERTAD DE OPERAR
SUBSITUYENDO TECNOLOGIAS
Technical audits of Expression Construct
for path to commercialization
DSF in Transgenic Grape Rootstocks LB
PIPRA Recombinase Gene-
Gene-Excision Vector
RRS
Eili/Lilly Recomb
Novartis Hyg
USDA
nos3’UTR 35S 3’UTR
Monsanto
34S Univ. California
Cyt Deam
Monsanto Company
35S NOS 3’UTR
Rockefeller University
RRS
Univ. California
No IPRS identified rpfF of X. campesti 34S
No IPRS identified rfpF of X. fastidiosa
rpfF of X. campesti
No IPRS identified
Monsanto ???? rpfB of X. campestris
rfpF of X. fastidiosa
Nos 3’UTR No IPRS identified
rpfB of X. campestris
PVPs Monsanto ????
Nos 3’UTR
Agro-bacteria
Mediated RB
Transformation RB
Caso 3
CONSIDERANDO TECNOLOGIA
DOMINIO PUBLICO O PATENTADA
3/2009 Revista Science: RNAI Descubrimiento del Año
Fire and Mello 2006 Premio Nobel Fisiología y Medicina
RNAi tecnología para suprimir
la expresión de genes de una
forma directa y eficiente.
Potencial para:
Terapéutica humano
Biotecnología en Agricultural
Otras
http://nobelprize.org/nobel_prizes/medicine/l
aureates/2006/press.html
Gene Suppression in Genetically Improved
Specialty Crops
1982, Calgene
Commercialized first
transgenic crop
Calgene FLAVRSAVRTM
Polygalacturonase
antisense
Delayed fruit ripening
Unpublished Data, 2009 Chi-Ham, Clark, Bennett
Caso 4
ARMANDO PAQUETES
TECNOLOGICOS
PIPRA’s Plant Transformation
Marker Free Technology Platforms
3. Excision marker
Univ California
1. Selectable markers
MAS Promoter, BRCD/Purdue 4. Transposase
NPTII Univ California
2. Constitutive Promoters
Univ California,
Cornell Univ.,
AgriFood Canada,
Plant Transformation
Technology Providers
Pre-negotiated licensing terms
humanitarian
use
PIPRA
Design, test, and disseminate plant research use
transformation vector Materials under
Research/Commercial
MTA/Licenses
commercial use
Royalty free
Fee
based
Revenue flow
Colaboraciones publico-privado para
desarrollar tecnologías.
Cecilia Chi-
Chi-Ham
Directora Ciencia y Tecnología
clchiham@ucdavis.edu
PIPRA, UC Davis
PROGRAMA FIA - PIPRA
LA GESTIÓN DE PROPIEDAD INTELECTUAL EN LA INNOVACIÓN
AGROALIMENTARIA
II. Formular Equipo
Develop a team capable of analyzing all
aspects of the product development