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Mathematical Modeling of Diabetes

Reference list
General
1. The world health report 2003: Today's challenges. [http://www.who.int/whr/2003/en]. Geneva, World Health Organization 2. International Diabetes Federation: IFD report 2003. [http://www.idf.org/home/index.cfm]. 3. Ratner RE: Type 2 diabetes mellitus: the grand overview. Diabet Med 1998, 14:54-57.

Review of models and computer tools


4. American Diabetes Association Consensus panel: Guidelines for Computer Modeling of Diabetes and its Complications. (Consensus Statement). Diabetes Care 2004, 27(11):2262-2265. 5. Boutayeb A, Chetouani A: A critical review of mathematical models and data used in diabetology, Biomed. Eng. Online, 2006, 5 (43). 6. Makroglou A, Li J, Kuang Y: Mathematical models and software tools for the glucose-insulin regulatory system and diabetes: an overview. Applied Numerical Mathematics 2006, 56:559573. 7. Landersdorfer CB, Jusko WJ, Pharmacokinetic/pharmacodynamic modelling in diabetes mellitus, Clinical pharmacokinetics 2008; 47(7):417-48.

Basic glucose-insulin system (physiology and regulatory feedbacks)


8. Bergman RN: The minimal model: yesterday, today and tomorrow. In The minimal model Approach and Determination of Glucose Tolerance Volume 7. Edited by: Bergman RN, Lovejoy JC. Boston: Louisiana state university Press; 1997:3-50. 9. Nucci G, Cobelli C: Models of subcatuneous insulin kinetics: a critical review. Computer Methods and Programs in Biomedicine 2000, 62:249-257. 10. Sundell J, Knuuti J: Insulin and myocardial blood flow. Cardiovascular Research 2003, 57(2):312319. 11. Finegood DT: Application of the minimal model of glucose kinetics. In The minimal model Approach and Determination of Glucose Tolerance Volume 7. Edited by: Bergman RN, Lovejoy JC. Boston : Louisiana state university Press; 1997:51-122. 12. Mari A: Mathematical modelling in glucose metabolism and insulin secretion. Current Opinion Clinical Nutrition Metabolism Care 2002, 5:495-501.

Subsystems and diagnostics: beta-cells, insulin, glycosylation


13. Bergman RN: Pathogenesis and prediction of diabetes mellitus: lessons from integrative physiology. Mount Sinai J Medicine 2002, 60:280-290. 14. De Gaetano A, Arino O: Mathematical Modelling of the Intravenous Glucose Tolerance Test. J Math Biol 2000, 40:136-168. 15. Kalergis M, De Grandpre E, Andersons C: The Role of the Glycemic Index in the Prevention and Management of Diabetes: A Review and Discussion. Canadian Journal of Diabetes 2005, 29(1):27-38.

16. Mukhopadhyay A, De Gaetano A, Arino O: Modelling the intravenous glucose tolerance test: A global study for single-distributed- delay model. Discrete and Continous Dynamical Systems Series B 2004, 4(2):407-417. 17. Rohlfing CL, Wiedmeyer HM, Little RR, England JD, Tennill A, Goldstein DE: Defining the relationship between plasma glucose and HbAlc: analysis of glucose profiles and HbAlc in the Diabetes Control and Complications Trial. Diabetes Care 2000, 25:275-278.

Slow disease progression


18. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419. 19. Levy JC, Matthews DR, Hermans MP: Correct Homeostasis Model Assessment (HOMA) evaluation uses the computer program (letter). Diabetes Care 1998, 20:2191-2192 20. Bagust A, Beale S: Deteriorating beta-cell function in type 2 diabetes: a long-term model. Q J Med 2003, 96:281-288. 21. De Winter W, et al, A Mechanism-based Disease Progression Model for Comparison of Longterm Effects of Pioglitazone, Metformin and Gliclazide on Disease Processes Underlying Type 2 Diabetes Mellitus, J. of Pharmacokinetics and Pharmacodynamics, 33(3), 2006: 313-343

Control: antidiabetics and exercise


22. Bellazzi R, Nucci G, Cobelli C: The Subcutaneous Route to Insulin Dependent Diabetes Therapy: Closed-Loop and Partially Closed-Loop Control Strategies for insulin Delivery and Measuring Glucose Concentration. IEEE Engrg Medicine Biol 2001, 20(1):54-64. 23. Derouich M, Boutayeb A: The effect of physical exercise on the dynamics of glucose and insulin. Journal of Biomechanics 2002, 35:911-917. 24. Lam ZH, Hwang KS, Lee JY, Chase JG, Walker GC: Active insulin infusion using optimal and derivative weighted control. Medical engineering physics 2002, 24:663-672. 25. Shimoda S, Nishida K, Sakakida M, Konno Y, ishinose K, Uehara M, Nowak T, Shichiri M: Closedloop subcutaneous insulin infusion algorithm with a short acting insulin analog for long-term clinical application of a wearable artificial endocrine pancreas. Frontiers Med Biol Eng 1997, 8:197-211.

Population models: Epidemiology, health economics


26. Anderson RM & RM, M (1991) Infectious diseases of humans (Oxford UP). 27. Paterson KR: Diabetes epidemiology: present and future. Diabet Med 1999, 16(6):446-7. 28. Boutayeb A, Chetouani A, Achouyab K, Twizell EH: A non-linear population model of diabetes mellitus. Journal of Applied Mathematics and computing 2006, 21:127-139. 29. Briggs A, Sculpher M, An Introduction to Markov Modeling for Economic Evaluation, PharmacoEconomics, 13(4), 1998 , 397-409 30. Bagust A, Hopkinson PK, Maier W, Currie CJ: An economic model of the long-term care burden of type II diabete. Diabetologia 2001, 44: 2140-2155.

Risk factors and complications


31. Diabetes Control and Complications Trials Research Group: The relationship of glycemic exposure (HbA1c) to the risk of development and progression of retinopathy in the diabetes control complications trial in insulin-dependent diabetes mellitus. Diabetes 1995, 44:968-983.

32. DCCT (Diabetes Control and Complications Trials) Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus. New England Journal of Medicine 1993, 329:977-986 33. DCCT Research Group: The absence of a glycemic threshold for the development of long-term complication: the perspective of the diabetes control complications trial in insulin-dependent diabetes mellitus. Diabetes 1996, 45:1289-1298. 34. Stevens RJ, Kothari V, Adler AI, Stratton IM, Holman RR, (UKPDS Group): The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56). Clinical Science 2001, 101:671-679. 35. Stevens RJ, Coleman RL, Adler AI, Stratton IM, Matthews DR, Holman RR: Risk Factors for myocardial Infarction Case Fatality and Stroke Case Fatality in Type 2 Diabete (UKPDS 66). Diabetes Care 2003, 27(1):201-207.

Whole-body approach (Archimedes)


36. Schlessinger L, Eddy DM: Archimedes: A new model simulating health care systems: the mathematical formulation. Journal of Biomedical Informatics 2002, 35(1):37-50. 37. Eddy DM, Schlessinger L: Archimedes: A trial-validated model of diabetes. Diabetes Care 2003, 26 (11):3093-3101. 38. Brandeau ML: Modeling complex Medical Decision Problems with Archimedes Model. Annals of Internal Medicine 2005, 143:303-304. 39. American Diabetes Association: Diabetes PHD and Archimedes. [http://www.archimedesmodel.com/pdf/archimedesintro_selfguided_press.pdf].

Agent-based modeling
40. Epstein JM, Robert A, Growing Artificial Societies: Social Science from the Bottom Up. MIT Press/Brookings Institution, 1996. 41. Amnah S et al, "A new hybrid agent-based modeling decision support system for breast cancer research", IEEE ICICT, IBA, Karachi, August 15-16, 2009.Breast Cancer DSS 42. Bonabeau E.; Agent-based modeling: methods and techniques for simulating human systems. PNAS 99(3): 7280-7287, 2002. 43. Grimm V, and Steven FR, Individual-based Modeling and Ecology, Princeton University Press, 2005. 44. Eubank S, Guclu H, Kumar VS, Marathe MV, Srinivasan A, Toroczkai Z, Wang N, Modelling disease outbreaks in realistic urban social networks, Nature. 2004 May 13; 429 (6988):180-4. 45. Gurarie D, S. Karl, In-host Dynamics of Malaria with Innate and Adaptive Immunity: Model Calibration for Agent Based Communities, J. Theor. Biol., 2009 (UR) 46. Gurarie D, Wang X, Bustinduy AL, and King CH, Modeling Catch-Up Growth Following Different Drug Treatment Regimens for Endemic Schistosomiasis, PLoSNTD, 2010 (UR) 47. Gurarie D, F.E. McKenzie, A stochastic model of immune-modulated malaria infection and disease in children, Math BioSciences, 210, 2, 2007, 576-597

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