XT-1800i

Haematology is
Fluorescence Flow Cytometry
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Success of excellence
built on the fluorescence flow cytometry
platform of sysmex xe-2100
reliable system requiring minimum main-
tenance ( just one shutdown cycle/day)
Valuable information
with diagnostic impact
excellent WBC differential with low review
rate due to specific fluorochrome staining
accurate RBC and PLT count determined
by a hydrodynamic focussing system
cumulative patient data and Delta Check
Easy to use
Windows

user interface
q-flags for quantitative flagging to adapt
diagnostic sensitivity to laboratory needs
comprehensive software programs
for internal and external QC on board
Cost effective
two random access selective test profiles
(CBC, CBC/DIFF)
real-time bidirectional
Host communication
network capability for integration
into a productive laboratory environment
sncs (sysmex network communication
system) for efficient user support
Flexibility
information processing unit (IPU)
with customisable display
tcmallows to connect two xt-1800i
instruments to a single IPU,
creating a common database
optional components
for flexible configurations
Design and specifications may be subject
to change due to further product development.
Technologies
Parameters
Throughput
Aspiration volume
Data storage
Quality control
Interfaces
Options
Configurations
Dimensions/weights
wxhxd [mm] /[kg]
fluorescence flow cytometry: WBC DIFF, IG
DC sheath flow method: RBC, HCT, PLT
cyanide-free SLS method: HGB
WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT
NEUT(%, #) LYMPH(%, #), MONO(%, #), EO(%, #), BASO(%, #),
RDW-SD, RDW-CV, MPV, P-LCR, PDW, PCT
research parameters: IG(%, #), OTHER(%, #)
stand-alone: 80 samples/hour
twin: 160 samples/hour
150L for sampler/manual closed mode
85L for manual open mode
40L sample volume for capillary mode
10,000 samples (incl. graphics)
5,000 patients information
1,000 selective test orders
20 QC files with 300 data points each
1 XbarM file with 300 data points
optional: sncs online qc
Host (Ethernet or serial),
graphic printer (parallel or USB)
rack sampler for 50 sample tubes
bar code reader for sampler mode, manual cap piercer unit
hand-held bar code reader, xt-pro software module
stand-alone (pim*), twin (tcm*)
530x630x720/59 (main unit with sampler)
280x400x355 /17 (pneumatic unit)
305x85x345 / 8 (IPU: information processing unit)
SYSMEX CORPORATION
1-5-1, Wakinohama-Kaigandori, Chuo-ku
Kobe 651- 0073, Japan
Phone +81 (78) 265- 0521 Fax +81 (78) 265- 0530
www.sysmex.co.jp
SYSMEX EUROPE GMBH
Bornbarch 1, 22848 Norderstedt, Germany
Phone +49 (40) 52726-0 Fax +49 (40) 52726-100
www.sysmex-europe.com
SYSMEX DEUTSCHLAND GMBH
Bornbarch 1, 22848 Norderstedt, Germany
Phone +49 (40) 53 41 02- 0 Fax +49 (40) 523 23 02
www.sysmex.de
SYSMEX UK LTD.
Sysmex House, Garamonde Drive, Wymbush
Milton Keynes, Buckinghamshire, MK8 8DF, U. K.
Phone +44 (870) 9029210 Fax +44 (870) 9029211
www.sysmex.co.uk
SYSMEX FRANCE S. A. S.
Z. I. Paris Nord II, 22 Avenue des Nations
BP: 51414 Villepinte 95944 Roissy CDGCedex, France
Phone +33 (1) 4817 01 90 Fax +33 (1) 4863 23 50
SYSMEX DANMARK
Msvrvej 23, 6051 Almind, Denmark
Phone +45 70204501 Fax +45 702045 41
www.sysmex.dk
SYSMEX SVERIGE
Marios Gata 13, 43437 Kungsbacka, Sweden
Phone +46 (300) 567202 Fax +46 (300) 567203
www.sysmex.se
SYSMEX NORGE
Hvamsvingen 24, 2013 Skjetten, Norway
Phone +47 63 8401 60 Fax +47 63 8431 40
www.sysmex.no
SYSMEX POLSKA SP. Z O.O.
Kopernik Office Building III
Al. Jerozolimskie 176, 02-486 Warsaw. Poland
Phone +48 (22) 5 7284- 00 Fax +48 (22) 5 7284- 10
www.sysmex.pl
* pim = patient information manager, tcm = twin configuration manager
Folder XT-1800i_PPS.qxd 01.03.2006 18:28 Uhr Seite 1
Compact fully automated Fluorescence Flow Cytometer
for high quality haematology analysis
State-of-the-art technology
A look inside
With fluorescence flow cytometry
individual blood cells stained by
fluorochromes are illuminated by a
semi-conductor laser beam, enab-
ling a sophisticated analysis based
on RNA/DNA content, cell size, and
inner cell complexity. Looking into
the cell and judging the metabolic
activities in respect to cell replica-
tion and protein synthesis offers
much advanced possibilities for the
determination of the cell type and
maturation stage.
The collection and fast processing
of three optical signals obtained
from each individual cell are the
basis for the cell identification.
When it comes to white blood cell
differentiation, analysing the cell
interior properties rather than cell
size leads to reliable classification
also in older samples and clearly
reduces interferences.
Using sysmex unique adaptive
cluster analysis system (acas)
instead of fixed discriminators re-
sults in correct cell clustering and
thus WBC differential counts also in
highly pathologic samples, accord-
ingly reducing the false positive
rate. The results are illustrated in
informative scattergrams.
In the optical unit of xt-1800i
a semi-conductor laser, the flow cell,
optical focussing systems and detectors
are combined in a sophisticated system.
The forward scattered light signal
(cell size information), the side scattered
light signal (internal cell structure)
and the side fluorescence light signal
(RNA/DNA information) of each cell are
analysed as it passes through the flow
cell.
RNA/DNA information
photo multiplier
(fluorescence light)
photo diode
(forward scattered light)
flow cell
semi-conductor laser
= 633nm dichroic
mirror
photo diode
(side scattered
light)
laser beam
= 633nm
internal cell structure
cell size
The various WBC populations and
immature precursor cells show a spe-
cific reaction with the fluorescent dye.
1 Neutrophil, 2 Eosinophil, 3 Basophil,
4 Monocyte, 5 Lymphocyte,
6 Band, 7 Metamyelocyte, 8 Myelocyte,
9 Promyelocyte, 10 Blast
1 2 3 4 5
6 7 8 9 10
The xt information
processing unit (IPU)
The main unit and the complete
operation of the xt-1800i is controlled
by the operator via the information
processing unit with interactive
menus. Intuitively understandable
icons are used for the graphical user
interface of Windows.
In the IPU data base, all analysis re-
sults and patient data including the
complete set of scattergrams and
histograms of up to 10,000 samples
are stored.
Back-up facilities on CD-RW offer
principally unlimited storage capa-
city. Quality control programs allow
unattended analysis of control blood
samples in closed auto-sampler mode
or in manual mode.
The multi-tasking computer system
permits real time bidirectional com-
munication with the Host computer
to request patient profiles for
discrete testing with patient demo-
graphical information and transmits
analysis results immediately after
analysis is completed. Even if the
system is operated offline and with-
out bar code system, selective sample
analysis is maintained by using the
work list function.
Flexibility
The sysmex xt-1800i is available in
multiple configurations. This offers
high flexibility and satisfies even the
needs of the most demanding hae-
matology laboratory.
A 50-tube auto-sampler can be
mounted on the main unit of the
analyser offering walkaway auto-
mation. This sampler system enables
continuous feeding of samples with
a throughput rate of 80 samples per
hour. A STAT function allows imme-
diate analysis of emergency samples.
If desired, it is possible to install a
manual cap piercer system instead
of the sampler.
No matter whether a manual or an
automated bar code reader is used,
adequate positive sample identifica-
tion gives confidence.
The complete main unit operation and all data management functions are performed on the
information processing unit (IPU).
The optional sampler unit of xt-1800i
ensures efficient operation and through-
put of 80 samples per hour, independent
of the parameter profiles analysed.
The cap piercer unit of xt-1800i.
Folder XT-1800i_PPS.qxd 01.03.2006 18:28 Uhr Seite 3
Compact fully automated Fluorescence Flow Cytometer
for high quality haematology analysis
State-of-the-art technology
A look inside
With fluorescence flow cytometry
individual blood cells stained by
fluorochromes are illuminated by a
semi-conductor laser beam, enab-
ling a sophisticated analysis based
on RNA/DNA content, cell size, and
inner cell complexity. Looking into
the cell and judging the metabolic
activities in respect to cell replica-
tion and protein synthesis offers
much advanced possibilities for the
determination of the cell type and
maturation stage.
The collection and fast processing
of three optical signals obtained
from each individual cell are the
basis for the cell identification.
When it comes to white blood cell
differentiation, analysing the cell
interior properties rather than cell
size leads to reliable classification
also in older samples and clearly
reduces interferences.
Using sysmex unique adaptive
cluster analysis system (acas)
instead of fixed discriminators re-
sults in correct cell clustering and
thus WBC differential counts also in
highly pathologic samples, accord-
ingly reducing the false positive
rate. The results are illustrated in
informative scattergrams.
In the optical unit of xt-1800i
a semi-conductor laser, the flow cell,
optical focussing systems and detectors
are combined in a sophisticated system.
The forward scattered light signal
(cell size information), the side scattered
light signal (internal cell structure)
and the side fluorescence light signal
(RNA/DNA information) of each cell are
analysed as it passes through the flow
cell.
RNA/DNA information
photo multiplier
(fluorescence light)
photo diode
(forward scattered light)
flow cell
semi-conductor laser
= 633nm dichroic
mirror
photo diode
(side scattered
light)
laser beam
= 633nm
internal cell structure
cell size
The various WBC populations and
immature precursor cells show a spe-
cific reaction with the fluorescent dye.
1 Neutrophil, 2 Eosinophil, 3 Basophil,
4 Monocyte, 5 Lymphocyte,
6 Band, 7 Metamyelocyte, 8 Myelocyte,
9 Promyelocyte, 10 Blast
1 2 3 4 5
6 7 8 9 10
The xt information
processing unit (IPU)
The main unit and the complete
operation of the xt-1800i is controlled
by the operator via the information
processing unit with interactive
menus. Intuitively understandable
icons are used for the graphical user
interface of Windows.
In the IPU data base, all analysis re-
sults and patient data including the
complete set of scattergrams and
histograms of up to 10,000 samples
are stored.
Back-up facilities on CD-RW offer
principally unlimited storage capa-
city. Quality control programs allow
unattended analysis of control blood
samples in closed auto-sampler mode
or in manual mode.
The multi-tasking computer system
permits real time bidirectional com-
munication with the Host computer
to request patient profiles for
discrete testing with patient demo-
graphical information and transmits
analysis results immediately after
analysis is completed. Even if the
system is operated offline and with-
out bar code system, selective sample
analysis is maintained by using the
work list function.
Flexibility
The sysmex xt-1800i is available in
multiple configurations. This offers
high flexibility and satisfies even the
needs of the most demanding hae-
matology laboratory.
A 50-tube auto-sampler can be
mounted on the main unit of the
analyser offering walkaway auto-
mation. This sampler system enables
continuous feeding of samples with
a throughput rate of 80 samples per
hour. A STAT function allows imme-
diate analysis of emergency samples.
If desired, it is possible to install a
manual cap piercer system instead
of the sampler.
No matter whether a manual or an
automated bar code reader is used,
adequate positive sample identifica-
tion gives confidence.
The complete main unit operation and all data management functions are performed on the
information processing unit (IPU).
The optional sampler unit of xt-1800i
ensures efficient operation and through-
put of 80 samples per hour, independent
of the parameter profiles analysed.
The cap piercer unit of xt-1800i.
Folder XT-1800i_PPS.qxd 01.03.2006 18:28 Uhr Seite 3
XT-1800i
Haematology is
Fluorescence Flow Cytometry
X
T
-
1
8
.C
A
.C
.
6
9
9
-
I
C
E
.
3
/
0
6
Success of excellence
built on the fluorescence flow cytometry
platform of sysmex xe-2100
reliable system requiring minimum main-
tenance ( just one shutdown cycle/day)
Valuable information
with diagnostic impact
excellent WBC differential with low review
rate due to specific fluorochrome staining
accurate RBC and PLT count determined
by a hydrodynamic focussing system
cumulative patient data and Delta Check
Easy to use
Windows

user interface
q-flags for quantitative flagging to adapt
diagnostic sensitivity to laboratory needs
comprehensive software programs
for internal and external QC on board
Cost effective
two random access selective test profiles
(CBC, CBC/DIFF)
real-time bidirectional
Host communication
network capability for integration
into a productive laboratory environment
sncs (sysmex network communication
system) for efficient user support
Flexibility
information processing unit (IPU)
with customisable display
tcmallows to connect two xt-1800i
instruments to a single IPU,
creating a common database
optional components
for flexible configurations
Design and specifications may be subject
to change due to further product development.
Technologies
Parameters
Throughput
Aspiration volume
Data storage
Quality control
Interfaces
Options
Configurations
Dimensions/weights
wxhxd [mm] /[kg]
fluorescence flow cytometry: WBC DIFF, IG
DC sheath flow method: RBC, HCT, PLT
cyanide-free SLS method: HGB
WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT
NEUT(%, #) LYMPH(%, #), MONO(%, #), EO(%, #), BASO(%, #),
RDW-SD, RDW-CV, MPV, P-LCR, PDW, PCT
research parameters: IG(%, #), OTHER(%, #)
stand-alone: 80 samples/hour
twin: 160 samples/hour
150L for sampler/manual closed mode
85L for manual open mode
40L sample volume for capillary mode
10,000 samples (incl. graphics)
5,000 patients information
1,000 selective test orders
20 QC files with 300 data points each
1 XbarM file with 300 data points
optional: sncs online qc
Host (Ethernet or serial),
graphic printer (parallel or USB)
rack sampler for 50 sample tubes
bar code reader for sampler mode, manual cap piercer unit
hand-held bar code reader, xt-pro software module
stand-alone (pim*), twin (tcm*)
530x630x720/59 (main unit with sampler)
280x400x355 /17 (pneumatic unit)
305x85x345 / 8 (IPU: information processing unit)
SYSMEX CORPORATION
1-5-1, Wakinohama-Kaigandori, Chuo-ku
Kobe 651- 0073, Japan
Phone +81 (78) 265- 0521 Fax +81 (78) 265- 0530
www.sysmex.co.jp
SYSMEX EUROPE GMBH
Bornbarch 1, 22848 Norderstedt, Germany
Phone +49 (40) 52726-0 Fax +49 (40) 52726-100
www.sysmex-europe.com
SYSMEX DEUTSCHLAND GMBH
Bornbarch 1, 22848 Norderstedt, Germany
Phone +49 (40) 53 41 02- 0 Fax +49 (40) 523 23 02
www.sysmex.de
SYSMEX UK LTD.
Sysmex House, Garamonde Drive, Wymbush
Milton Keynes, Buckinghamshire, MK8 8DF, U. K.
Phone +44 (870) 9029210 Fax +44 (870) 9029211
www.sysmex.co.uk
SYSMEX FRANCE S. A. S.
Z. I. Paris Nord II, 22 Avenue des Nations
BP: 51414 Villepinte 95944 Roissy CDGCedex, France
Phone +33 (1) 4817 01 90 Fax +33 (1) 4863 23 50
SYSMEX DANMARK
Msvrvej 23, 6051 Almind, Denmark
Phone +45 70204501 Fax +45 702045 41
www.sysmex.dk
SYSMEX SVERIGE
Marios Gata 13, 43437 Kungsbacka, Sweden
Phone +46 (300) 567202 Fax +46 (300) 567203
www.sysmex.se
SYSMEX NORGE
Hvamsvingen 24, 2013 Skjetten, Norway
Phone +47 63 8401 60 Fax +47 63 8431 40
www.sysmex.no
SYSMEX POLSKA SP. Z O.O.
Kopernik Office Building III
Al. Jerozolimskie 176, 02-486 Warsaw. Poland
Phone +48 (22) 5 7284- 00 Fax +48 (22) 5 7284- 10
www.sysmex.pl
* pim = patient information manager, tcm = twin configuration manager
Folder XT-1800i_PPS.qxd 01.03.2006 18:28 Uhr Seite 1