FC Derm(SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa

29 March 2011 Paper 1 (3 hours)

All questions are to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer) Al die vrae moet beantwoord word. Elke vraag moet in n aparte boek (of boeke indien meer as een nodig is vir n vraag) geskryf word

Write short notes on a) Apocrine sweat glands. b) Paccinian corpuscles. c) Langerhans cells. d) Fillagrin. e) Embryology of subcutaneous fat. Skryf kort aantekeninge oor a) Apokriene sweetkliere. b) Pacini liggaampies. c) Langerhans selle. d) Filaggrien. e) Embriologie van die subkutane vet. Discuss shock in detail. Bespreek skok breedvoerig. a) Discuss the role(s) that the skin plays as i) A physical and chemical barrier. ii) An excretory organ. Write short notes on the lymphatic system. Bespreek die rol/rolle wat die vel speel as i) n Fisiese en chemiese sperder. ii) n Uitskeidingsorgaan. Skryf kort aantekeninge oor die limfatiese sisteem.

(5) (5) (5) (5) (5) [25] (5) (5) (5) (5) (5) [25] [25] [25] (10) (7) (8) [25] (10) (7) (8) [25] (8) (9) (8) [25]

2 2 3

b) 3 a) b) 4

Describe a) Processes that lead to blistering in human skin. b) The functions of the glomus body in human skin. c) The functions of the mast cell in relation to its structure. Beskryf

a) b) c)

Prosesse wat aanleiding gee tot blaasvorming in menslike vel. Die funksies van die glomusliggaam in menslike vel. Die struktuur funksie verwantskap van die massel.

(8) (9) (8) [25]

FC Derm(SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa

30 March 2011 Paper 2 (3 hours)

All questions are to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer) Al die vrae moet beantwoord word. Elke vraag moet in n aparte boek (of boeke indien meer as een nodig is vir n vraag) geskryf word

Write short notes on the following a) Choristomas. b) Teratomas. c) Hamartomas. Skryf kort aantekeninge oor die volgende a) Koristome (Choristomas). b) Teratome. c) Hamartome. Describe the techniques behind the following investigations and briefly outline relevance to clinical dermatology a) Direct and indirect immunofluorescence testing. b) Tzanck smear test. c) KOH (potassium hydroxide) test. d) PCR (polymerase chain reaction). their

(7) (8) (10) [25] (7) (8) (10) [25]

(10) (5) (5) (5) [25]

Beskryf die tegniek van die volgende ondersoeke en beskryf kortliks die toepassing daarvan in kliniese dermatologie a) Direkte en indirekte immunofluoressensie toetsing. (10) b) Tzanck smeer toets. (5) c) KOH (kaliumhidroksied) toets. (5) d) PKR (polimerase kettinreaksie). (5) [25] Describe a) Movement of substances across membranes. b) Synaptic transmission. c) Regulation of vitamin D formation and the physiological actions of Vitamin D. Beskryf a) Beweging van substanse oor membrane. b) Sinaptiese oordrag. (5) (5) (15) [25] (5) (5)

c)

Regulasie van vitamien D sintese en die fisiologiese aksies (actions) van vitamien D. (15) [25] [25] [25]

4 4

Discuss the role of viruses in human oncogenesis. Bespreek die rol van viruses in menslike onkogenese.

FC Derm(SA) Part I THE COLLEGES OF MEDICINE OF SOUTH AFRICA Incorporated Association not for gain Reg No 1955/000003/08 Part I Examination for the Fellowship of the College of Dermatologists of South Africa 31 March 2011 Paper 3 (3 hours)
All questions are to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer) Al die vrae moet beantwoord word. Elke vraag moet in n aparte boek (of boeke indien meer as een nodig is vir n vraag) geskryf word

Write short notes on the following a) The differences between a carcinoma and a sarcoma. (5) b) The differences between an ephelis, a lentigo, a melenocytic naevus and a melanoma. (8) c) The basic principles of immunohistochemistry as applied routinely in the histopathology laboratory. (12) [25] Skryf kort aantekeninge oor die volgende a) Die verskille tussen karsinoon en sarkoom. (5) b) Die verskille tussen efelis, n lentigo, n melanositiese nevus en melanoom. (8) c) Die basiese beginsels van immunohistochemie, soos roetienweg toegepas in die histopatologie laboratorium. (12) [25] Discuss the following statements a) Epidermal cells communicate with each other. b) TNF is the most important mediator of skin disease. c) Atopic eczema is a disorder of barrier function. Bespreek die volgende stellings a) Epidermale selle kommunikeer met mekaar. b) TNF is die belangrikste mediator van velsiekte. c) Atopiese ekseem is die gevolg van barrir disfunksie. a) b) c) a) b) c) Draw and label a longitudinal section through a hair follicle. Discuss the difference between soft and hard keratin. Discuss the function of hair Maak n geannoteerde diagram van n vertikale snit deur n haarfollikel. Bespreek die verskille tussen harde en sagte keratien. Bespreek die funksie van hare. (8) (7) (10) [25] (8) (7) (10) [25] (10) (10) (5) [25] (10) (10) (5) [25]

a) b)

Give a detailed diagrammatic representation of the dermoepidermal junction. (15) Tabulate the common autoantibodies that may be found in various autoimmune diseases. (10) [25] Maak n gedetaileerde diagram van die dermoepidermale aansluiting. (15) Tabuleer die algemene outoantiliggame wat gevind word in verskeie (various) outoimmuunsiektes. (10) [25]

a) b)