Immunocal

Immunocal

Immunocal - US Patents
- 5,290,571 5,451,412 5,230,902 5,456,924 5,888,552 5,846,939
- IMMUNOCAL® Medical Breakthrough
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Immunotec Research Ltd. announces the release of a powerful and unique nutraceutical. IMMUNOCAL®, a 100% natural
bonded cysteine dietary supplement with superior nutritional value, is formulated to contain significantly high amounts of
the rare precursors (building blocks) of GLUTATHIONE (GSH). GSH is the cells' own natural and most vital antioxidant,
and detoxifier. GSH serves to reinforce both healthy and deficient immune systems. Immunocal® is essentially lactose-,
and fat-free (under 1%), and has no known side effects. Watch Video about Immunocal/Glutathione (short video in
english 9 minutes Video) >> Buy Immunocal 40 % DicountBuy Immunocal 40 % Dicount

IMMUNOCAL®
Medical Breakthrough
Immunotec Research Ltd. announces the release of a powerful and unique nutraceutical. IMMUNOCAL®, a 100% natural
bonded cysteine dietary supplement with superior nutritional value, is formulated to contain significantly high amounts of
the rare precursors (building blocks) of GLUTATHIONE (GSH). GSH is the cells' own natural and most vital antioxidant,
and detoxifier. GSH serves to reinforce both healthy and deficient immune systems. Immunocal® is essentially lactose-,
and fat-free (under 1%), and has no known side effects.

It was the original discovery of the importance of GSH (Glutathione) in boosting the immune system that led to the
development of IMMUNOCAL®. As a result of many years of research which began in the late 1970's, Dr. Gustavo
Bounous (world expert on GSH) and a team of McGill University physicians and scientists demonstrated that by using a
whey protein isolate in the diet of experimental animals, the animals' life span was increased by as much as 30% to 50%.
This effect was a result of immune-function enhancement which occurred in a variety of ways, including a heightened
resistance to infection, a lowered incidence of cancer, and a greater immune response when challenged with bacteria,
viruses, or foreign antigens.

Glutathione is a substance made up of three amino acids: glutamic acid, glycine, and most importantly, cysteine which
gives the molecule its biological activity. GSH is found in almost all human cells. GSH cannot be transported into cells; it
must be manufactured within the cells. The only way to do this is by supplying the appropriate building blocks
(precursors), which are the active ingredients in IMMUNOCAL®.
In the course of normal cell metabolism, by-products called 'oxyradicals', or 'free radicals', are created, which, unless
immediately neutralized, can lead to poor health. High GSH levels are the key to this protective response. Other
antioxidants such as Vitamin C and E depend on GSH for their own function.
GSH is concentrated in the liver, where it functions as a key detoxifying agent. Multiple toxins, pollutants and carcinogens
are eliminated from our bodies via GSH enzymatic pathways.
Our immune system depends on the proper response to foreign challenges like bacteria, viruses and parasites, and
abnormal cells. GSH plays a crucial role in the function and multiplication of our lymphocytes to combat these organisms.
IMMUNOCAL® is the only natural product patented to safely raise and sustain GSH. Other methods to raise intracellular
glutathione in the past have included N-acetylcysteine (NAC) as well as other drugs. However, these have very short-
lived effects. Actual ingestion of glutathione, although possible, has clearly been shown to be ineffective, as it is almost
completely digested and excreted intestinally. Dr. James Balch stated in his book The Super Antioxidants, "people have
thrown money away taking glutathione supplements that their body cannot use." The isolated amino acid cysteine, when
taken by itself, is poorly absorbed and potentially toxic. Other forms of whey protein have variable or negligible
bioavailability of GSH precursors and are easily denatured (damaged) in the manufacturing and handling process,
leading to low bioactivity.*
*For more information, please see "GSH, Your Body's Most
Powerful Healing Agent" or "Breakthrough in Cell Defense"
available at book stores or through the return address on this
pamphlet. These two books contain exhaustive references.
IMMUNOCAL®/HMS 90® is a patented, highly concentrated protein that in nature is most similar to mother's milk. In
Canada it is called HMS 90® to denote Humanized milk Serum. It shares with mother's milk many immune promoting
benefits.
High in rare cysteine-delivering properties, it is prepared using a propriety process leading to a non-denatured 90%
protein powder, preserving the original bioactivity of the thermolabile components. In other words, this guarantees the
highest level of GSH-promoting activity available. It is the only concentrate patented for immuno-optimizing and
glutathione-enhancing effects.
Although marketed in Europe, North Africa, and the Far East by pharmaceutical firms, this all-natural product can be
purchased without prescription in North America. It is listed in the Physicians Desk Reference Drug catalog, and the
Pharmacist's Red Book of prescription products, and it meets criteria for reimbursement for medicare/medicaid.
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 Immunocal

Clinical trials in the USA, Canada, and Japan point to the benefits of IMMUNICAL®. A series of case reports on the use of
IMMUNOCAL® in urogenital cancer was published in the journal of Anti-Cancer Research (Anti-Cancer Research 2000
Nov-Dec; 20(6c):4785-92.) The data corroborates the anti-cancer, anti-tumor effect on cancer seen in earlier animal
studies and small human studies. In another study by Ammunomed accepted for presentation at the 2002 Int. meeting of
the institute of Human Virology, IMMUNOCAL® alleviated side effects of HAART treatment in AIDS patients, and
contributed to weight gain and marked improvement. The Nova Scotia Cancer Center (Dalhousie University) has
published on IMMUNOCAL® and metastatic cancer and has undertaken a phase III trial on breast cancer. Japanese
studies have shown its positive effects on hepatitis B. IMMUNOCAL® has been demonstrated to combat major bacterial
and viral infections. Also, a phase II trial on Cystic Fibrosis is underway in Montreal. Immunotec Research Ltd. has
established a fund to promote further studies.
These statements have not been evaluated by the Food and Drug Administration. This product in not intended to
diagnose, treat, cure or prevent any disease.

IMMUNE SYTEM
Clinical studies have proven that immune depressed individuals have lower GSH concentrations. Healthy people also
experience a drop in GSH levels when fighting disease. Lymphocytes, cells vital for your immune response, depend on
GSH for their proper function and replication.
IMMUNOLOGY 61:503-508, 1987

ANTIOXIDANT FUNCTIONS
Antioxidants are well-documented to play vital roles in health maintenance and disease prevention. GSH is the cell's own
major antioxidant. It recycles other antioxidants, such as vitamins C and E.
BIOCHEMICAL PHARMACOLOGY 47:2113-2123, 1994

TOXINS, POLLUTION, RADIATION

GSH detoxifies pollutants, carcinogens, and poisons, including many found in fuel exhaust and cigarette smoke. It
retards damage from radiation such as that caused by the increased losses of the ozone layer. It reduces neurotoxicity,
an underestimated hazard.
ANNUAL REVIEWS OF BIOCHEMISTRY 52:711-760, 1983

AGING PROCESS
By the age of 40 there is a precipitous drop in GSH levels. Lower glutathione levels are evident in many diseases
associated with aging including cataracts, Alzheimer's disease, Parkinson's, arteriosclerosis, etc.
JOURNAL OF CLINICAL EPIDEMIOLOGY 47:1021-26, 1994

HEALTHY INDIVIDUALS & ATHLETES

Intense muscular activity generates oxyradicals leading to muscle fatigue and poorer performance. GSH neautralizes
exercised-induced oxyradicals. A recent study with healthy individuals showed a 13% muscular performance increase
when Immunocal was used for 90 days.
AMERICAN J. RESP.CRIT. CARE MED. 159:A719, 1999

CARDIOVASCULAR APPLICATIONS
GSH has been shown to prevent atheriosclerosis and even reverse it. GSH retards the oxidation of cholesterol and is
greatly beneficial in preventing heart disease, strokes, and reperfusion injury.
NUTRITION REVIEWS 54:1-30, 1996

INFECTIOUS & AUTOIMMUNE DISEASES

GSH supports and rebalances the body's anti-infective defenses. This impacts bacterial infections, autoimmune
dysfunctions, Chronic Fatigue Syndrome, herpes, hepatitis, etc.
IMMUNOLOGY 61: 503-508, 1987

CANCER
GSH eliminates many carcinogens and also maintains immune function. IMMUNOCAL® has Method-of-Use Patents for
preventing and treating cancer. It can reduce side effects from some cancer therapies.
CANCER LETTERS 57:91-94, 1991

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 Immunocal

NEUROLOGICAL DISEASE
Low GSH levels is a common denominator in neurodegenerative diseases such as Multiple Sclerosis (MS), "Lou
Gehrig's Disease" (ALS), Alzheimer's, Parkinson's and others.
THE LANCET 344:796-798, 1994

PULMONARY DISORDERS
Chronic Bronchitis, Cystic Fibrosis, and Asthma have been clinically shown to impact and lower glutathione levels.
Repleting glutathione shows clinical benefits.
AMERICAN J. MED. SCI. 307:119-127, 1994

AIDS
IMMUNOCAL® HAS A Method-of-Use Patent for HIV/AIDS treatment. Low Glutathione levels correlate with poor survival
in AIDS victims. Scientific studies demonstrate the benefits of enhancing GSH in AIDS patients.
PROC. NATIONALACAD. SCIENCE USA94:1967-72, 1997

Nutrition Facts Serving Size 1 pouch (10g) Servings per Container 30

Amount per Serving Calories 40
% Daily Value*
Total Fat 0g 0%
Sodium 25mg 1%
Total Carbohydrates 0%
Protein 9g
Calcium 6% Iron 4%
Not a significant source of calories from fat, saturated fat, cholesterol, dietary fiber, sugars, vitamin A and vitamin C
*Percent Daily Values are based on a 2,000 calorie diet. Meets criteria for reimbursement.

Instructions for use: One pouch (10g) daily; mix and shake vigorously in a closed container with 2 oz. of your favorite
beverage, preferable nonacidic, at room temperature or cooler. Allow 2 minutes to dissolve, then add 4 oz. more liquid,
shake and drink. Immunocal can also be added to milk, cereals, apple sauce or other foods, as part of a healthy dietary
regimen.

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