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How Does the Brain Communicate?

Organization of the Nervous System

How is the Brain Organized? The Endocrine System What Makes Us Who We Are?

Dendrites

Soma

Myelin Sheath

Axon

Terminal Buttons and Synapses

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

In the spinal cord, information travels from sensory neurons to motor neurons.

Motor neurons send information from your spinal cord to your arm muscles, signaling them to contract, jerking your hand away.

Spinal cord (cross section)

Sensory neurons send information from your (hot) fingertips up your arm and to your spinal cord.

You touch the hot stove; the heat registers in your skins sensory receptors.

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Soma

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Dendrites

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Axon

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Myelin Sheath

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Synaptic Cleft

Terminal Buttons and Synapses

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Presynaptic Neuron

Postsynaptic Neuron

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Synaptic Vesicles Neurotransmitter Molecules

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Handout

dendrites

Direction of Neural Messages

Myelin Sheath

axon

Cell body/nucleus

Axon bulb

Inside Electrode

Axon

Outside Electrode

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

50

Inside Electrode
Millivolts

-50

Axon

Outside Electrode

-100 Milliseconds

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

50

Inside Electrode
Millivolts

-50

Axon

Outside Electrode

-100 Milliseconds

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Action Potential
50

No Action Potential
50

Millivolts

OR
-50

Millivolts

-50

-100 Milliseconds

-100 Milliseconds

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Refractory Period
50

Inside Electrode
Millivolts

-50

Axon

Outside Electrode

-100 Milliseconds

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Presynaptic neuron

Na+ leaks into neuron Excitation

Postsynaptic neuron

Inhibition

CI- leaks into neuron

Neurons can simultaneously receive both excitatory and inhibitory signals from other neurons. The cell will fire an action potential only if it reaches threshold.

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

1
2

Synthesis and storage of neurotransmitter molecules in synaptic vesicles

Reuptake of neurotransmitters sponged up by the presynaptic neuron

Release of neurotransmitter molecules into synaptic cleft

4
3

Inactivation (by enzymes) or removal (drifting away) of neurotransmitters

Binding of neurotransmitters at receptor sites on postsynaptic membrane

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Question
Suki takes a drug that causes potassium ions to leave her neurons. This drug is likely to produce what type of effect on her neurons? a. Increased firing b. Excitation c. Inhibition d. Both excitation and inhibition

More illustrations

http://science.education.nih.gov/supplements/nih2/addiction/activiti es/lesson2_neurotransmission.htm

Central Nervous System (CNS) Brain Spinal Cord Peripheral Nervous System (PNS) Nerves that carry signals to and from the brain and spinal cord

Nervous system
Central nervous system (CNS) Peripheral nervous system (PNS)

Brain

Spinal cord

Autonomic nervous system (ANS)

Somatic nervous system

Sympathetic division

Parasympathetic division

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Visual sensory information travels to the eye

Sensory pathways carry visual information to the brain Interneurons process information within the brain Motor pathways carry information away from the brain

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Sympathetic Nervous System


Dilates pupils, inhibits tears
Inhibits salivation (dry mouth) Dilates bronchi, increases respiration Accelerates heart rate Goose bumps; activates sweat glands Inhibits activity Releases adrenalin Stimulates glucose release Contracts blood vessels Relaxes bladder; inhibits elimination Promotes ejaculation and vaginal contractions

Parasympathetic Nervous System


Contracts pupil, stimulates tears
Activates salivation Constricts bronchi, calms respiration Slows heart rate No goose bumps; inhibits sweat glands Stimulates activity Stops releasing adrenalin Slows glucose release Dilates blood vessels Constricts bladder; stimulates elimination Stimulates genitals

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Question
Which branch of the automatic nervous system is most active when we are relaxed? a. Parasympathetic b. Sympathetic c. Endocrine d. Spinal

Nervous System Made Easy

http://www.youtube.com/watch?v=3XEoz_rf40A

Pons Cerebellum Medulla

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Midbrain

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Septum

Amygdala

Hippocampus

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

H.M.
Henry Gustav Molaison (February 26, 1926 December 2, 2008) -Severe uncontrolled epilepsy -destroyed hippocampus -seizures stopped but developed anterograde amnesia (could not store new memories -His case played a very important role in the development of theories that explain the link between brain function and memory -UC San Diego where it was sliced into histological sections on December 4, 2009 http://video.pbs.org/video/2365029824/ Key ethical aspect of the scientists studying HMs brain after death?

Hypothalamus Thalamus

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Parietal lobe

Occipital lobe Frontal lobe

Temporal lobe

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Primary motor area

Brocas area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Production of Speech

Brocas Area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Primary somatosensory area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Primary visual area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Wernickes area

Primary auditory area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Comprehension of Language

Wernickes Area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Stimulus in Left Half of Visual Field

Stimulus in Right Half of Visual Field

Fixation Point

Left Eye Left Hemisphere


(Control of Right Hand)

Right Eye Right Hemisphere


(Control of Light Hand)

Optic Nerves Information Delivered to Left Visual Processing Area

Severed Corpus Callosum Information Delivered to Right Visual Processing Area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Stimulus in Left Half of Visual Field

Stimulus in Right Half of Visual Field

Fixation Point

Left Eye Left Hemisphere


(Control of Right Hand)

Right Eye Right Hemisphere


(Control of Light Hand)

Optic Nerves Information Delivered to Left Visual Processing Area

Severed Corpus Callosum Information Delivered to Right Visual Processing Area

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Question
Billy suffered a stroke on the left side of his brain. Most of his left frontal lobe was destroyed. What symptoms would you most expect to see in Billy as a result of this damage? a. Paralysis on the right side of his body and an inability to speak b. Paralysis on the right side of his body and an inability to understand speech c. Paralysis in the left leg, partial deafness, and stuttering d. Paralysis on the left side of his body and an inability to understand speech

http://www.youtube.com/watch?v=D1zkVBH Ph5c http://www.youtube.com/watch?v=8hC6NG QReL4 (stop at 5:50)

Hypothalamus Pituitary Glands


Thyroid Gland Adrenal Gland Pancreas Ovary
(in Female)

Testis
(in Male)

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Question
Juanita was just frightened by a snake. Which of the following endocrine glands most likely played the biggest role in her response to danger? a. Thymus b. Thyroid c. Adrenal Cortex d. Adrenal Medulla

Hypothalamus Pituitary Glands Thyroid Gland Adrenal Gland Pancreas Ovary


(in Female, Release Estrogens)

Testis
(in Male, Release Androgens)

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

How Does the Brain Communicate?

How do Neurotransmitters Work?

Organization of the Nervous System

How is the Brain Organized?

How do We Study the Brain?

The Endocrine System

What Makes Us Who We Are?

Question
Dr. Jasper is a scientist who believes that environment influences can affect the way that our genes are expressed during development. In his studies, he is examining how maternal environment can affect fur coloring in subsequent generations of rats. Dr. Jasper is LEAST likely to agree that our traits are the result of______ a. Epigenetics b. Interactionism c. Nature forces d. a and b

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