! Copyright of Professor John Murtagh and Australian Doctor. This patient handout may be photocopied or printed out by a doctor free of charge for patient information purposes. Hangover What is a hangover? A hangover is the extreme drained and uncomfortable feeling the morning after a bout of excessive drinking of alcohol. It is a type of acute drug toxicity. The main symp- toms are headache, nausea and fatigue. What is the cause of the sickness? There are several factors involved in lead- ing to the toxic effects of alcohol on the brain and rest of the body and particularly to the state of dehydration which is a key feature. How bad you feel after an evenings drinking depends partly on your basic con- stitution, your conditioning to drinking, and what and how much you have drunk. Most alcoholic drinks contain substances called congeners that combine with the amount and strength of the alcohol to give a drinking bout its hangover effect. Because alcohol is a diuretic drug it causes an increased output of urine, thus leading to dehydration of the body. What are the most potent drinks? Brandy, bourbon and red wine produce the most hangovers. Gin and vodka contain few congeners and are the least likely to cause a hangover. Champagne or sparkling chardonnay is also a potent drink, particu- larly on an empty stomach. Any fizzy drink is not advisable during a solid drinking ses- sion because the gas increases the rate of absorption of alcohol. What other factors contribute to hangovers? l Smoking an important contributing factor. l Drinking on an empty stomach. l Fast drinking, especially skolling. What are the risks? Next-day performance can be a problem and dangerous in people with responsible jobs requiring alertness and fine skills such as transport drivers and pilots. Making a habit of partying with hangovers can lead to chronic alcohol dependence and toxicity. What are some of the myths of alco- hol folklore? There are several traditional beliefs asso- ciated with drinking but their validity is questionable. l It is risky to mix your drinks, for exam- ple, to have beer after champagne or whisky, or wine after gin, or red wine after white wine. Although mixing may con- tribute to a hangover there is no evidence that it is harmful. It is best to mix water with alcoholic drinks, for example, min- eral water to follow or precede alcohol. l A hair of the dog that bit you eases the hangover, that is, try to alleviate a hangover by having a drink or two the fol- lowing morning. This may help you feel better due to taking fluid and reversing the withdrawal symptoms but it is a danger- ous practice if used regularly. It can be a forerunner of alcohol dependence. l Drinking coffee sobers you up. This may be partly true but coffee also has a diuretic effect. How can hangovers be prevented or minimised? Much of this advice is commonsense and you can set your own strategies. l Drink alcohol on a full stomach. Combine it with food any kind of food. This is probably the best single thing you can do besides drinking less to reduce the severity of a hangover. l Select alcoholic drinks that suit you. Avoid drinking excessive champagne on an empty stomach when you arrive at a func- tion. l Avoid fast drinking keep it slow. Choose your drinks for their flavour not their kick and enjoy the taste of each relaxing sip. l Restrict the quantity of alcohol you drink set yourself reasonable limits and stick to them. l Dilute your drinks adding non-alcohol liquid mixtures to strong drinks is effec- tive. Look for the tall container of soda water, water or tonic. Mix your drinks by having a glass of water or non-alcoholic juice between alcoholic drinks. l For beer drinkers use light beer. l Avoid or restrict smoking while you drink. l Drink three large glasses of water before going to bed. What is the treatment? l Drink lots of fluids, preferably water. l Drink sweetened orange juice or tomato juice. Such fruit juices help eliminate alco- hol. l A drink of honey in lemon juice helps. l Tea (preferable) and coffee are suitable drinks but follow coffee with water. l Have a substantial meal but avoid fatty food. l Take two paracetamol tablets for discom- fort, especially for headache. Brain Stomach Pancreas Heart Liver Kidneys Organs of the body susceptible to damage by excessive/prolonged use of alcohol