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What is a biotechnology product?

A biotechnology product is one manufactured by recombinant DNA technology, one where


genetic manipulation of cells is required, or a monoclonal antibody.

Red biotechnology:
It is concerned with the discovery and development of innovative drugs and treatments. A key
requirement was an increasing understanding of how proteins function, their roles in
communication between and within cells, and the diseases caused when these proteins
malfunction.

Medicinal Biotechnology (Red Biotechnology) - An introduction:
Since ancient times, humankind has tried to cure diseases with drugs. Whereas previously
primarily active ingredients from nature (plants, minerals) were used, from the 19th century on,
synthetic active ingredients started to make a major contribution. Biopharmaceuticals,
biotechnology products occupy an increasingly important place in the fight against diseases.
With the advancement of technology new products are manufactured and are increased day by
day. Biotechnology drugs comprise the fastest-growing sector in drug development, and they are
expected to account for more than 50% of all new product approvals by 2015 and 71% by 2025.
And it is reported that More than 350 million patients benefiting from medicines manufactured
through biotechnology Treatment or prevention of cancers, heart attacks, stroke, multiple
sclerosis, leukemia, diabetes, rare and other diseases. Today 650 new biotech medicines and
vaccines currently being tested for more than 100 diseases.
Here is list of some drugs available in market, which are used for curing hundreds of diseases
such as diabetes, arthritis, respiratory diseases, breast cancer, blood cancer and HIV Diseases and
all other diseases can be cured.
Drug Name Company Name Description
Sargramostim Bayer Healthcare For the treatment of cancer and bone marrow transplant
Romiplostim Novo Nordisk Treatment of chronic immune thrombocytopenic purpura.
Salmon Calcitonin Sanofi Aventis For the treatment of post-menopausal osteoporosis
Secretin Chirhoclin inc For diagnosis of pancreatic exocrine dysfunction and gastrinoma
Tenecteplase Genentech Inc. For treatment of myocardial infarction and lysis of intracoronary
emboli

Vasopressin Parke davis div
warner lambert
For the treatment of enuresis, polyuria, diabetes insipidus, polydipsia
and esophageal varices with bleeding.
Drug Name Company Name Description
Insulin Novo Nordisk prescribed for diabetes mellitus
Etanercept Enbrel treats autoimmune diseases by interfering with tumor
necrosis factor
Abciximab Eli Lilly and
Company
Used for the prevention of cardiac ischemic complications in
patients
Anakinra Amgen Inc For the treatment of adult rheumatoid arthritis and treatment
of Neonatal-Onset Multisystem Inflammatory Disease
(NOMID).
Asparaginase Merck & Co. Inc For treatment of acute lympocytic leukemia and non-
Hodgkins lymphoma
Leuprolide Abbott Laboratories
Ltd.
It is also used to treat uterine fibroids and endometriosis.
Mecasermin Tercica inc,Insmed
inc
For the long-term treatment of growth failure in pediatric
patients
Muromonab Centocor Ortho
Biotech Inc.
For treatment of organ transplant recipients, prevention of
organ rejection
Choriogonadotropin alfa App pharmaceuticals
llc
used to treat female infertility
Darbepoetin alfa Amgen Inc. For the treatment of anemia (from renal transplants or
certain HIV treatment)
Follitropin beta Emd serono inc For treatment of female infertility
Gramicidin D Johnson & Johnson
Healthcare
For treatment of skin lesions, surface wounds and eye
infections
Imiglucerase Genzyme corp For the treatment of Gaucher's disease (deficiency in
glucocerebrosidase)
Adalimumab(HUMIRA) Abbott Ltd Used as TNF inhibiting anti-inflammatory drug.
Glatiramer acetate Teva Pharmaceutical It is immunomodulator drug currently used to treat multiple
sclerosis.
Natalizumab Biogen Idec Inc. For treatment of multiple sclerosis.
Cetuximab (Erbitux) ImClone , Eli Lilly
and Company
Used as epidermal growth factor receptor (EGFR) inhibitor
used for the treatment of metastatic colorectal cancer and
head and neck cancer.
Omalizumab Genentech Inc. For treatment of asthma caused by allergies
OspA lipoprotein Amgen Lab For prophylactic treatment of Lyme Disease
Rituxan (rituximab) Genentech Use for treatment of Rheumatoid arthritis.
Oxytocin Abbott laboratories,
Teva
To assist in labor, elective labor induction, uterine
contraction induction
Palivizumab Abbot Laboratories
Ltd,Medimmune Inc.
For prophylaxis of respiratory diseases casued by respiratory
syncytial virus.
Avastin (bevacizumab) Genentech Used to inhibit angiogenesis process in tumor
Palivizumab Medimmune Inc.
Abbott Ltd.
For prophylaxis of respiratory diseases caused by respiratory
syncytial virus.
Interferon beta 1-a Merck Serono used to treat multiple sclerosis
Pegaspargase Enzon Inc. For treatment of acute lymphoblastic leukemia
Insulin glargine (Lantus) Sanofi-Aventis It is a long-acting basal insulin analogue, given once daily to
help control the blood sugar level of those with diabetes.
Rasburicase GlaxoSmithKline
Inc.
For treatment of hyperuricemia, reduces elevated plasma
uric acid levels.
Conclusion: We can say that biotechnology has changed the therapeutic landscape for many
severe diseases. It has the potential to bring a new revolution through personalized medicines
which can be used for the welfare of human kind. In future the medicinal biotechnology will play
a important role and cure the side diseases which has no cure till now.

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