A biotechnology product is one manufactured by recombinant DNA technology, one where
genetic manipulation of cells is required, or a monoclonal antibody.
Red biotechnology: It is concerned with the discovery and development of innovative drugs and treatments. A key requirement was an increasing understanding of how proteins function, their roles in communication between and within cells, and the diseases caused when these proteins malfunction.
Medicinal Biotechnology (Red Biotechnology) - An introduction: Since ancient times, humankind has tried to cure diseases with drugs. Whereas previously primarily active ingredients from nature (plants, minerals) were used, from the 19th century on, synthetic active ingredients started to make a major contribution. Biopharmaceuticals, biotechnology products occupy an increasingly important place in the fight against diseases. With the advancement of technology new products are manufactured and are increased day by day. Biotechnology drugs comprise the fastest-growing sector in drug development, and they are expected to account for more than 50% of all new product approvals by 2015 and 71% by 2025. And it is reported that More than 350 million patients benefiting from medicines manufactured through biotechnology Treatment or prevention of cancers, heart attacks, stroke, multiple sclerosis, leukemia, diabetes, rare and other diseases. Today 650 new biotech medicines and vaccines currently being tested for more than 100 diseases. Here is list of some drugs available in market, which are used for curing hundreds of diseases such as diabetes, arthritis, respiratory diseases, breast cancer, blood cancer and HIV Diseases and all other diseases can be cured. Drug Name Company Name Description Sargramostim Bayer Healthcare For the treatment of cancer and bone marrow transplant Romiplostim Novo Nordisk Treatment of chronic immune thrombocytopenic purpura. Salmon Calcitonin Sanofi Aventis For the treatment of post-menopausal osteoporosis Secretin Chirhoclin inc For diagnosis of pancreatic exocrine dysfunction and gastrinoma Tenecteplase Genentech Inc. For treatment of myocardial infarction and lysis of intracoronary emboli
Vasopressin Parke davis div warner lambert For the treatment of enuresis, polyuria, diabetes insipidus, polydipsia and esophageal varices with bleeding. Drug Name Company Name Description Insulin Novo Nordisk prescribed for diabetes mellitus Etanercept Enbrel treats autoimmune diseases by interfering with tumor necrosis factor Abciximab Eli Lilly and Company Used for the prevention of cardiac ischemic complications in patients Anakinra Amgen Inc For the treatment of adult rheumatoid arthritis and treatment of Neonatal-Onset Multisystem Inflammatory Disease (NOMID). Asparaginase Merck & Co. Inc For treatment of acute lympocytic leukemia and non- Hodgkins lymphoma Leuprolide Abbott Laboratories Ltd. It is also used to treat uterine fibroids and endometriosis. Mecasermin Tercica inc,Insmed inc For the long-term treatment of growth failure in pediatric patients Muromonab Centocor Ortho Biotech Inc. For treatment of organ transplant recipients, prevention of organ rejection Choriogonadotropin alfa App pharmaceuticals llc used to treat female infertility Darbepoetin alfa Amgen Inc. For the treatment of anemia (from renal transplants or certain HIV treatment) Follitropin beta Emd serono inc For treatment of female infertility Gramicidin D Johnson & Johnson Healthcare For treatment of skin lesions, surface wounds and eye infections Imiglucerase Genzyme corp For the treatment of Gaucher's disease (deficiency in glucocerebrosidase) Adalimumab(HUMIRA) Abbott Ltd Used as TNF inhibiting anti-inflammatory drug. Glatiramer acetate Teva Pharmaceutical It is immunomodulator drug currently used to treat multiple sclerosis. Natalizumab Biogen Idec Inc. For treatment of multiple sclerosis. Cetuximab (Erbitux) ImClone , Eli Lilly and Company Used as epidermal growth factor receptor (EGFR) inhibitor used for the treatment of metastatic colorectal cancer and head and neck cancer. Omalizumab Genentech Inc. For treatment of asthma caused by allergies OspA lipoprotein Amgen Lab For prophylactic treatment of Lyme Disease Rituxan (rituximab) Genentech Use for treatment of Rheumatoid arthritis. Oxytocin Abbott laboratories, Teva To assist in labor, elective labor induction, uterine contraction induction Palivizumab Abbot Laboratories Ltd,Medimmune Inc. For prophylaxis of respiratory diseases casued by respiratory syncytial virus. Avastin (bevacizumab) Genentech Used to inhibit angiogenesis process in tumor Palivizumab Medimmune Inc. Abbott Ltd. For prophylaxis of respiratory diseases caused by respiratory syncytial virus. Interferon beta 1-a Merck Serono used to treat multiple sclerosis Pegaspargase Enzon Inc. For treatment of acute lymphoblastic leukemia Insulin glargine (Lantus) Sanofi-Aventis It is a long-acting basal insulin analogue, given once daily to help control the blood sugar level of those with diabetes. Rasburicase GlaxoSmithKline Inc. For treatment of hyperuricemia, reduces elevated plasma uric acid levels. Conclusion: We can say that biotechnology has changed the therapeutic landscape for many severe diseases. It has the potential to bring a new revolution through personalized medicines which can be used for the welfare of human kind. In future the medicinal biotechnology will play a important role and cure the side diseases which has no cure till now.