c-prostaglandins modifier d-leukotrienes modifier e-non of the above 2-The action of histamine is : a-capillary constriction b-elevation of blood pressure c-stimulation of gastric secretion d-skeletal muscle paralysis e-slowing the heart rate 3-ne of the following antibiotics is resistant to penicillinase : a-penicillin ! b-penicillin " c-flo#apen d-ampicillin e-amo#icillin $- %nderal is : a-similar in action to ergotamine b-similar in action to tubocurarine c-used as an antihistamine d-pure b -adrenergic receptor blocker &- 'ifampicin is indicated for treatment of : a-impaired fat absorption b-pulmonary emboli c-tuberculosis d-neoplastic disorders e-psoriasis (- )hich of the following is non selective b1 blocker * a-labitolol b-terazosine c-cloridine d-captopril e-verapamil +- The ,atin abbreviation for - .fter /eals - is : a- a0c0 b- a0a0 c- p0c0 d- i0c0 e- c0c0 1- The latin abbreviation for - 2our Times 3aily - is : a- a0c0 b- a0a0 c- p0c0 d- 40i0d0 e- c0c0 5- The latin abbreviation for - 6very 7ight - is : a- a0c0 b- o0n0 c- p0c0 d- i0c0 e- c0c0 18- 6rythroped . : a-is effective against " 9ve :occi b-is a macrolide antibiotic c-can increase g0i0t0 motility d-could be used in pregnant women if need e-all of the above
49
49
11- 2or the treatment of anaphylactic shock use :
a-salbutamol b-diphenhydramine c-acetazolamide d-epinephrine e-aminophylline 12- .llopurinol is used as : a-analgesic agent b-uricosuric agent c-antiinflamatory agent d-antipyretic agent e-agent which increases renal tubular reabsorption .llopurinol inhibits #anthine o#idase; reducing the conversion of hypo#anthine and #anthine to uric acid and resulting in direct inhibition of purine biosynthesis due to elevated o#ypurine concentration <negative feedback=0 #ypurinol also inhibits #anthine o#idase0 >o anyway you have dramatically decreased uric acid concentrations; decreased renal tubular transport of uric acid; and then the side effect of increased tubular reabsorption of calcium0 13- )hich of the following is 7T betamethasone side effect * .-cataract b-hypoglycemia c-skeletal muscle weakness d-sodium retention e-lowered resistance to infections 1$- . disease which is due to viral infection : a-poliomyelitis b-rabies c-chicken po# d-herpes e-all of the above 1&- The mechanism of action of atropine is : a-muscarinic antagonist b-muscarinic agonist c-nicotinic antagonist d-nicotinic agonist e-non of the above 1(- /yocardial muscle tissue property to generate electrical is : a-inotropy b-chronotropy c-automaticity d-contractility e-non of the above - 3romotropic effect- 1+- The heart?s dominant pacemaker is : a- .! node b- >. node c-pukinje fiber d-internodal pathways e-non of the above 11- .denosine is used for : a-ventricular arrythmias b-atrial bradycardia c-supraventricular tachycardia d-supraventricular bradycardia e-non of the above
49
49
15- .denosine @ produces which of the following :
a-facial flushing b-dyspnea c-marked tachycardia d- a and b e- a ; b and c 28- )hich of the following is responcible for buffering a-magnesium b-chloride c-bicarbonates d-potassium e-troponin 21- 'espiratory acidosis is due to : a- 2 removal b- 2 retention c- :2 removal d- :2 retention e-non of the above 22- )hich of the following is 7T colloid solution * a-albumin &A b-ringer?s solution c-de#tran d-beta starch e-albumin 28A 23- The term shock signifies : a-hyperperfusion b-hypoperfusion c-tachycardia d-bradycardia e-non of the above 2$- %n treatment of shock ; which of the following should be considered* a-airway control b-%! of crystalloid solution c-dopamine to support blood pressure d-monitor heart rhythm e-all of the above 2&- )hich of the following is released by bacterial infection*<B0 by bacterial cell wall during there growth= a-endoto#in b-e#oto#in c-antibiotics d-cytoto#in e-non of the above
2(- the amount of water in adult male is about: a-2&A b-(8A c-18A d-18A e-1+A 2+- )hich of the following are causes of oedema* a- %ncrease hydrostatic pressure b- 3ecrease oncotic pressure c-capillary permeability d- a and b e- a ; b and CDEFGDH IJEFKLGM NGODJKGM NJPLQ 21- @atients prescribed non reversible monoamine o#idase inhibitor should be advised not to consume food containing tyramine because this combination causes: a-postural hypotension b-hallucinations c-anaphylactic shock d-muscle weakness and tremor e-acute adrenergic crisis including sever hypertention 25- :oncerning :R 2 inhibitors ; which is 7T true* a-they have lower risk gastric adverse reactions b-good evidence about their effectiveness c-cardiac to#icity is a recent concern of this class d-they usually administrated twice daily e-combination with non selective agents give more effective action 38- %n the treatment of osteoporosis which of the following is 7T true* a-alendronate should be taken (8 min0 before breakfast b-:a and vit0 3 are essential c-hormone replacement therapy should be considered d-outcome should be assessed with periodic bone density e-ralo#ifeno is selective oestrogen modulator 31- )hich of the following is the first choice in acute gout* a-allopurinol b-indomethacin c-colchicine d-probencid e-sulfinylpyrazone 32- )hich of the following is 7T a risk factor for osteoparalysis* a-minimal e#ercise b-low calcium intake c-male gender d-family history e-minimal e#posure to sunlight 33- 6arly symptoms of aspirin poisoning are : a-lethergy S fatigue b-skin rash S headache c-throbbing headache S dizziness d-fluid retention hypotension e-ringing in the ears S blurred vision 3$- )hich of the following is 7T true about infi#imuab a-%,-1 blocker b-used for treatment of severe rheumatoid arthritis c-may increase risk of infections d-administered as %! infusion e-postadministration reactions include fever S chills
%nfl#imab is anti T72 CDEFGDH IJEFKLGM NGODJKGM NJPLQ 3&- . disease modifying drugs in rheumatoid arthritis: a-gold preparations b-hydro#ychloro4uine c-methotre#ate d- a and b e- a ; b and c
3(- . patient who is admitted through the 60'0 with an initial diagnosis arterial fibrillation a-slow ventricular response using verapamil b-start lidocaine infusion c- considered anticoagulation with warfarine d- a and c e- b and c 3+- )hich of the following is true about surgical prophyla#is * a-it is given to treat surgery associated infections b-it is given to reduce the possibility of surgical site infection c-should always be given regardless type of surgery d-should be continued for + days after surgery e-all are true 31- )hen diagnosis of diabetes to be considered : a-)T: count with differential b-oral glucose tolerance test c- UT.1c d- a and b e- b and c 35- The usual daily dose of phenytoin in the range of: a- 1-& mg b- 1&-(8 mg c- 388-(88 d -should be continued for + days after surgery e-all are true $8- "oals of diabetes mellitus management include : a-reduce onset of complications b-control symptoms of diabetes c-near normal glycemic control and UT.1c d- a and b e- a ; b and c $1- )hen dosing insulin which of the following is true* a-initial dose 80( u V kg V day split 2V3 a0m and 1V3 p0m b-regular 7@U ratio is 1 : 1 or 1 : 2 c-dose may need to be increased during acute illness d- b and c e- a ; b and c $2- )hat first line agent may be considered for an obese type 2 * a-glyburinid b-insulin c-metformin d-nateglinid e-repaglinid
$2- These are non a4ueous pharmaceutical solutions: a-otic soln0 ; mouth washes and nasal soln0 b-essences ; collodions an eli#irs c-gargles ; douches and irrigation soln0 d-syrups ; mucillages and collodions e-enemas ; liniments and spirits $$- )hich of the following drugs e#hibits dose dependant pharmaceutical therapeutic doses * a-7a valproate b-phenytoin c-lithium d-4uinidine e-carbamazepine $&- @ropranolol is often prescribed with hydralazine to a-reduce the refle# tachycardia b-prevent the accumulation of hydralazine0 c-prevent systemic lupus < >,6 = due to hydralazine0 d-prevent oedema e-increase absorption of hydralazine $(- The ability of a li4uid to dissolve is : a-hydrophilicity b-miscibility c-immiscibility d-solubility e4uilibrium $+- )hich of the following is 7T correct * a-glitazones are ineffective as mono therapy b-"%T disturbance are common side effects of glycosidase inhibitors-a c-start with small dose of oral agent and triturate up to 1-2 weeks d-life style modification should not be enforced if an oral agent to be started e-lisepro is rapid acting insulin to be dosed immediately before meals
$1- %n :U2 management the following is not correct: a-.:6%s such as lisinopril improves left ventricular function and reduces mortality -blocker such as carvidailol may have beneficialb b- effect in selected patient c-spironolactone should be avoided because of the great risk of hypokalemia d-non drug therapy includes appropriate fluid and dietary sodium-restriction e-symptomatic improvement is one of the major assessment criteria for proper therapy $5- )hich of the following is 7T a primary literature a-gournal of pharmacy practice b-applied therapeutic S clinical use of drug c-new 6ngland Wournal of medicine d-,oncet e- W./. &8- 'eferences to check compatibility of drugs in parentral administration: a- /6':X %nde# b-handbook on injectable drugs c-micromedi# d- a and b e- b and c &1- )hen a :7> depressant is prescribed ; which of the following is 7T taken at the same time* a-analgesic b-verapamil c-aspirin d-diphenhydramine e-orange juice &2- . $ mg dose of lorazepam administered to an adult will act as : a-analgesic b-hypnotic c-diuretic d-antihistaminic e-antiulcerant &3- The drug of choice to control pain during acute myocardial infarction is : a-nalo#one b-bethidine c-morphine d-celeco#ib e-napro#en &$- )hat is a major contraindication to the use of an T: sympathomimetic drug a-gastric ulcer b-uncontrolled hypotension c-severe asthma d-rheumatoid arthritis e-hypertension
&&-:ategory : in 23. for drug used in pregnancy : a- controlled studies fail to demonstrate a risk to the fetus in the trimester and there is no evidence of risk in later trimester b- fetal risk 7T demonstrated in animal studies but there are no controlled studies in pregnant women or animal reproduction studies have shown an adverse effect that was 7T confirmed in controlled studies in women during trimester c-either animal study have revealed adverse effect on the fetus and there are no controlled human studies or studies in animal and women are not available d- There is positive evidence of human fetal risk but the benefits of use in pregnant woman may be acceptable despite the risk &(- )hat advice would you give to a patient prescribed rifampicin* a-take this medication with food or milk b-avoid multivitamine preparations during treatment c-avoid taking paracetamol during treatment d-possible discolouration of skin is of no importance e-this medication may cause discolouration of urine &+- :orrect method of parentral administration of potassium is : a-fast %0!0 injection b-slow %0!0 injection c-%0/0 injection d-%@<intraperitoneal= injection &1- )hich route of administration would provide the most rapid onset of action response to morphine * a-oral b->0:0 c-%0!0 d-%0/0 e-rectal &5- The long term administration of thiazide diuretics re4uires : a- X9 b- 7a9 c- :a99 d- :3 e- acetate (1- )hen concidering drug therapy for hypertention ; which is true* a-combination of drugs always preferred b-hydralazine is first line therapy in young hypertension c-furosemide should be administrated before meal to improve absorption d-beta-blokers should be avoided in asthmatic patient e- .:6%s are recommended in pregnant women
(2- )hich of the following is 7T used in theophylline to#icity management : a-symptomatic control of seizures with benzodiazepine b-activated charcoal to enhance elimination c- b blocker for tachycardia d-control vomiting with metoclopramide e-methylphenidate to reduce e#cessive sedation (3- 'egarding the use of .:6%s : a-associated hypokalemia could be avoided by giving X-supplement b-effective in reducing proteinurea in diabetic patient c-most common side effect is chronic dry cough d-a good first line treatment for hypertensive diabetic e-dose should be started low and triturated gradually upward in need ($- 'egarding treatment of digo#in to#icity: a-verify time of last time b-check /g and X levels and correct if needed c-monitor 6:" d-no antidote for digo#in e-supportive care (&- The antimalarial to be avoided in glucose-(-phosphate dehydrogenase deficiency : a-prima4uine b-4uinine c-chloroguanide
(1-The following is 7T characteristic of solution: a-thermodynamically stable b-composed of two or more component that e#ist in one phase c-homogenous d-the solvent and solute can be separated by filtration e-solute doesn?t precipitate as time passes 69- Role of carbidopa i !rea!"e! of #ar$i%oi%"& a- 'ero!oi re(p!a$e b- dopa"ie a)oi%! c- *ecrea%e dopa"ie i perip+eral ,e%%el d- *opa"ie a!a)oi%! e- -./0 a!a)oi%! 12- Role of 3-bloc$er% i a)ia& 4444&
D2- ;+ic+ of !+e follo;i) are c+arac!eri%!ic for Er<!+roped a- o! effec!i,e a)ai%! 6 +,e cocci b- o! "acrolide a!ibio!ic c- ca icrea%e 67/ "o!ili!< d-ca o! (%ed i pre)a! ;o"e if eeded e- oe of !+e abo,e D0- ;+ic+ of !+e follo;i) are c+arac!eri%!ic for Er<!+ro%ie> a-o! effec!i,e a)ai%! 6F,e cocci b- +a% a"io )l<co%ide a!ibio!ic c-decrea%e 67/ "o!ili!< d-%+o(ld o! be (%ed i pre)a! ;o"a if eed e-%+o(ld be (%ed i pre)a! ;o"a if eed D9-!+e op!i"al %iCe for op+!+al"ic drop%>- Y 18Zg D?- :"p+e!a"ie i% (%ed i> defect of awareness in the brain of children0 DB-if pac$a)ed are ;ri!!e for e8pir< Go,e"ber 9226 i! "ea !+a! ca be (%ed !ill a- 0 Go,e"ber b- ?0 Go,e"ber D--/+e "ec+ai%" of ac!io of 3(%piroe !+ro()+ a--./ a)oi%!
0?6-podocodeie i% (%ed i dry cough 0?1-;+ic+ of !+e follo;i) o! (%ed i e"er)ec< ./G>- a- f(ro%e"ide b- pidolol c- labe!olol d- 4444& 0?D-*o8or(bici %ide effec! >- a- cardiac to#icity b- ep+ro!o8ici!< c- po%!(ral +<po!e%io d- arr+<!+"ia 0?9- ;+ic+ of !+e follo;i) o! (%ed i !!! of a%!+"a>- a- 39 a)oi%! b-39 a!a)oi%! 0B2- 5+ic+ of !+e follo;i) i% al$<la!i) a)e! ad a!icacer a-,ibla%!ie b- ci%pla!i c- :yclophosphamide d- ,icri%!ie 0B0- @er< %"all "olec(leL0 par! M %ol(ble i 02=222 par! of ;a!er a- fairl< %ol(ble b- slightly soluble K-i""i%cible d- "i%cible e- i%ol(ble 0B9-beCoil o! %ol(ble i .9H b(! %ol(ble i beCee i 9-Z c a- polar b- o polar c-%ol(ble d- i%ol(ble e- %li)+!l< polar 0B?- oe of !+e follo;i) i% "e"ber of p+eo!+iaCie% )ro(p prochlorperazine antipsychotic 0BB-pri"idoe i% prodr() for L a!iepilep!ic dr() M 0 0B-- *ail< reco""eded do%e for folic acid $88-&88 Zg 0B6- *ail< reco""eded do%e for ,i!& K i "ale >- a-?2")Rda< b--2 ")Rda< c-92")Rda< d-922 ")Rda< e- B22 ")Rda<
0B1- *ail< reco""eded do%e for ,i!& K i fe"ale >- a-?2")Rda< b--2 ")Rda< c-92")Rda< d-922 ")Rda< e- B22 ")Rda<
[ 0BD- "a8& dail< do%e for parace!a"ol i%
L $888 mg = 0B9- Er)o! al$aloid% i% (%ed a% ttt migraine 0-2- 3(fferi) a)e! (%ed i op+!+al"ic drop% !o>- decrease irritation to eye and increase stability 0-0-pico%(lp+a!e i% (%ed a% la#ative 0-9- *i)o8i !o8ici!< icrea%e ;i!+>- a- real fail(re b- +epa!ic p! c- :%!+"a!ic p! 0-?- :ll !+e follo;i) are %ide effec! of oral co!racep!i,e e8cep!>- a-+<per!e%io b-;ei)+! )ai c- .<per)l<ce"ia d- diCCie%% e- co%!ipa!io 0-B-;+ic+ of !+e follo;i) arco!ic% o! (%ed !oda<>- a- "orp+ie b- +eroi c- ico!ie d- codeie 0--- dr() %!ored i !+e bod< i>- a- fa! b- "(%cle c- coec!i,e !i%%(e d- lipid e- pro!ei 0-6-;+ic+ of !+e follo;i) do%a)e for" are fa"o(%>- a- %ol(!io= )el= oi!& b- oi! = )el = %ol(!io c- oi!= %ol(!io = )el e- %ol(!io = oi! = )el 0-1- i ca%e of +epa!ic or real fail(re ;+ic+ "(%cle rela8a! i% reco""eded >-
0-D- .epari ca be "oi!ored !+ro()+ >- a- :#// b- 7GR c-#/ d-7T . @artial Thromboblastine Time < time taken by plasma to clot= 0-9-Ei8opari i% ad"ii%!ra!ed>- a- 7T b- 7@ c- >0:0 d- 7@ if(%io
062- if dr() pro!ei bidi) icrea%ed or decrea%ed>- a- +alf life ] b- +alf life \ c- %ide effec! ] d- ac!io ] e- a;b 060-?rd )eera!io cep+alo%pori +a%>- a- 6F ol< b- 6-,e ol< c- "9ve ; "-ve 069-%ol(bili!< e+aced !+ro()+ >- a- red(ce par!icle %iCe b- icrea%e %(rface area c- icrea%e par!icle %iCe d- decrea%e %(rface area e- :^3 06?- de!er"ia!io aal<%i% of %ol(!io deped o a-a!(re of %ol(!e b- !<pe of %ol(!io c-aal<Cer d- a0b 06B-;+e (%e liU(id or oi!& !o di%%ol,e !+e %olid i! i% called >- levigation 06-- p+e<!oi ac! o
>- ".T. receptor
066- G':7*% prod(ce ac!io !+ro()+>- decrease prostaglandin synthesis 061- ;+ic+ of !+e follo;i) o! c+arac!eri%!ic of !+eop+<llie>- a- rela8a!io !o broc+ial %"oo!+ "(%cle b- icrea%e cardiac co!rac!ili!<= KH c- a(%ea = abdo"ial di%!(rbace e- co,(l%io d- sedation 06D- ;+a! i% dr() of c+oice i !!! of broc+o%pa%"Ra%!+"a>- a-salbutamol Lalb(!rol M b-!+eop+<llie c-propraolol d-e%"olol e- U(iidie 069- ;+ic+ of !+e follo;i) ca(%e depre%%io >- a- a"picilli b- reserpine
012- #RE@HK i% !rade a"e (%ed a%>-L!iclopdieM a- a!icoa)(la! b- a!ipla!elle! c- a!ibio!ic d- a!i a%!+"a!ic 010- po(d Y 80$&3 kg 019- %(%!aied relea%e do%a)e for" i% (%ed !o a-icrea%e +alf life b- dr() +a,e lo; !+erape(!ic ide8 c- 444444444&& 01?- dr() af!er "e!aboliCed i li,er i! ;ill beco"e>- a-polar b- o polar c- lipop+ilic d- i%ol(ble 01B- loadi) do%e defii!io 01-- i p+a%e 0 i "(%cle co!rac!io occ(r>- a-depolariCa!io for $ i b- repolariCa!io !o ca o(! 1+(- half life of drug is + days U) can taken:- a- every day b- twice daily c- twice weekly d- every week
1++- diltiazim classified as : 0 :a channel blocker
1+1-T carotine is precursop of : a-retinol b- thiamine c-riboflavin d- pyrido#ine e- calcefirol
1+5- electrical property which produce impulses called : a-conduction b-automaticity c-velocity d- e#citability 118- infusion of hypotonic solution in blood cause : a= shriniking of blood cell b= hemolysis c= hyperglycemia d= hypoglycemia e= b 9 d
111- infusion of hypertonic solution in blood cause : a= shriniking of blood cell b= hemolysis c= hyperglycemia d= hypoglycemia e= b 9 d CDEFGDH IJEFKLGM NGODJKGM NJPLQ 11$- denaturation will happened in body for which compounds* a-penicillin b- proteins c- lipid d-carbohydrate e-000000000000 11&- major metabolism proccess in "%T is:- a-hydrolysis b- acetylation c- o#idation d-conjucation 11(- dosage form of nitroglycren when used in malignant hypertension * a-%! b-%/ c- >0: d- infusion e- transdermal 11+- drug induced lupus like syndrom is associated with antihypertinsive * a-mini#idil b- hydralazine c- dio#ide d-nitroprusside 7a e- acebutol
111- hypothirodism cause :- a-weight gain b- hypoglycemia c-low body temp d-00000000000 115- .:6 % mechanism of action as antihypertension *** - inhibition of converting angiotensin % to angiotensin %% 158- .bout definition of first pass effect ; it increase with:- a- increase rate of absorption b- increase biotransformation c- increase pka d- .ST 151- metal used in rheumatoid arthiritis : gold 152- low density lipoprotein<,3,= act as : a-carrier c+ole%!erol i pla%"a b- !ra%por! fa!!< acid c- )ood lipopro!ie& 153- true solutions another name is:- a- +o"o)eo(% b- +e!ero)eo(% c-e"(l!io d- %(%pe%io 09B-abo(! op+!+al"ic prepara!io a% %i)le do%e ;+ic+ i% fal%e>- a-%!erile b- p(rified c-%+o(ld co!ai pre%er,a!i,e d-444&& 09--"o%! of dr()% are > a-5ea$ elec!rol<!e b-Go elec!rlol<!e c-Go ioic d-'!ro) elec!rol<!e e-3F K 091- a!ip%e(do"oa% dr() > a-"e!roidaCole b-<%!a!i c- pri"aU(ie d-,aco"<ci
906- pe!o8ip+<lli (%ed for > a-perip+eral ,a%odila!or b-.<per!e%io c-Ko()+ %(ppre%%a! 7dica!io% @entofyllin is indicated in diseases; causing disorders in the peripheral perfusion; and in diabetes; atherosclerotic and inflammatory disorders; including shank ulcers^ gangrene^ diabetic angiopathy^ intermittent claudication^ 'aynaud_s disease0 %n acute disorders of the brain perfusion; including ischemic stroke and resultant conditions0 .cute disorders of the retinal blood supply0 90D- or"al ;a!er (%ed for > a-E<e preparp!io b-#are!ral prepara!io c-'ol(!io d-E"(l!io e-E8!eral prepara!io 909- cef!aCidi"e > 3rd generation 992-abo(! a"io )l<co%ide = ;+ic+ i% o! !r(e W a-.a% )ra" S,e ac!i,i!< b-Pe%% !o8ici!< c-Garro; !+erape(!ic d-Ko"pa!ible ;i!+ o!+er dr() e-_%(all< 7@ = 7T 990- abo(! or epiep+rie o! !r(e >- a-icrea%er 3&# b-,a%oco%!ric!i,e c-(%ed i cardio)eic %+oc$ d-effec!i,e orall< e-'&K 999- #.:RT:KHN7GE/7K KHG'/:G/ >- a-`ero order b-0%! order c-9d order d-Ti8ed order e-: F 3
99?- 5+ic+ of !+e follo;i) i% GH/ predi%oloe %ide effec! W a-ca!arac! b-+<po)l<ce"ia c-%$ele!al "(%cle ;ea$e%% d-%odi(" re!e!io e-lo;ered re%i%!ace !o ifec!io% 99B- 5+e cocideri) dr() !+erap< for +<per!e!io = ;+ic+ i% !r(eW a-co"bia!io of dr()% al;a<% preferred b-+<dralaCie i% fir%! lie !+erap< i <o() +<per!e%io c-f(ro%e"ide %+o(ld be ad"ii%!ra!ed before "eal !o i"pro,e ab%orp!io d-b-blo$er% %+o(ld be a,oided i a%!+"a!ic pa!ie! e- :KE7% are reco""eded i pre)a! ;o"e CDEFGDH IJEFKLGM NGODJKGM NJPLQ 99--%ol(!io% are be!!er !+a %olid do%a)e for" coC> a-:cc(ra!e do%e b-Ea%< !o +adle c-Tore %!able d-Oa%!er ac!io e-3 F K 996- He of follo;i) GH/ (%ed !o co,er bi!!er !a%!e>- a-Oil" coa! b-E!eric coa! c-6ridi) of !able! 991-;+ic+ of follo;i) !ric<clic a!idepre%%a! i% !er!iar< a"ieW .mitriptyline 99D- a!i+<per!e%i,e (%ed i pre)ac< W .lpha /ethyldopa 999-dr() (%ed for pep!ic (lcer WL ,osec= 9?2- dr() if(%io ra!e i% 9")a$)a+r = if(%ed for 09 +o(r% = for 12$) pa!ie!& ;+a! i% !o!al do%eW L9812809MY06D2 ") 9?0-L 6T#M "ea>- "ood /anufacturing @ractice a-6ood Ta(fac!(ri) #ro!ocol b-6ood Ta( fac!or #rod(c! c-6eeral Ta(fac!(ri) #ro!ocol d-6eeral Ta(fac!(ri) #rod(c!
9??- accordi) !o %!eril "e!+od ;+ic+ of !+e follo;i) i% fal%e abo(! fil!!era!io>- bcde fg hij able to filtter viscous substance CDEFGDH IJEFKLGM NGODJKGM NJPLQ 9?B- ;+e <o( $o; !+e pre%er,a!i,e (%ed ;i!+ a!i bio!ic i% o! %(i!able <o( "a$e>- a- (%e ao!+er oe i% %(i!able b- add ao!+er !o icrea%e i! i% ac!i,i!< c- (%e !o; or "ore pre%er,a!i,e "a< icrea%e !+e ac!i,i!< ad "a< beco"e %(i!able d- aFc 9?-- del!iaCe" ^ ifedipie ^flocdipie ac! a% - block :a to intracellular S increase metabolism from storage site 23(- .ll of this affect rate of absorption e#cept:- a- chemical stability b- @U c-protein binding d- .ST e- TS: 237-Aiteplase &streptokinase used in:- ( Pulmonary emboli ) 231-:holystyramin resin act by :- anion e#change 23-!"e #on#. $f ioni%ed & unioni%ed #al#ulated by (&enderson "asselba#"k e'uation) 2()- *ig"t sensitive drug s"ould be storage in:- a-+olorless glass b-+olorless plasti# c-Amber glass d-Amber plasti# e-*ig"t resistant #ontainer 9B0-Elec!ro"a)e!ic ra<% >- )a""a ra<%= 8-ra<%& 9B9-K<clop+o%p+a"ide L%ide effec!%M :ppe!i!e lo%%k ab%ece of "e%!r(al period%k color c+a)e i %$ik diarr+eak )eeral (;ell feeli)k +air lo%%k a(%eak %$i ra%+k %!o"ac+ di%co"for! or paik !e8!(re c+a)e i ail%k ,o"i!i)k ;ea$e%%& 2$3-%soproterenol< %soprenaline = adrenergic agonist medication& 2((-+oal tar uses in (psoriasis).^ dadr(f 9B--/+e "o%! co""o reac!io ca!al<%ed b< c<!oc+ro"e #B-2 i% a monoo#ygenase 2$(-The most common phase % reaction is o#idation 2$+-)hich f The 2ollowing 7T `sed %n @eptic `lcer >- a-/e!rac<clie b- 7!racoaCole c-Te!roidaCole d-bi%"(!+ %(b%alic<la!e e-clari!+ro"<ci 2$1-)hich f The 2ollowing act as alpha 1 blocker :- a- +<draC<lie b-!eraCocie c-propraolol d-cap!opril e- cloidie 2$5-comparison between sterile water Swater for injection:- a- p<ro)e free b-free fro" %od& K+loride c- 7%o!oic d-free fro" bac!eria e- :^K 2&8- aunidine has similar action to :- a-procaia"ide b- lidocaie c-propraolol d- +<dralC<ie 2&1- )hich of the following drug has side effect lupus like syndrome : a- lidocaie b-"io8dile c- procaia"ide d-+<droc+loro!+iaCide 2&2- ver dose of digo#ine we use:-<anti dote 2.T 2ragment =0 2&3- .mpicilline has similar action of:- a- !e!rac<clie b-cep+ale8i c-clora"p+iicol d-a"i$acie 2&$- :ephalosporin act as:- a-7+ibi!or% of cell "e"brae f(c!io b-i+ibi!or% (cleic acid %<!+e%i% c-7+ibi!or% of pro!ei %<!+e%i% d-7+ibi!or% of cell ;all %<!+e%i% e-7+ibi!or% of "e!aboli%" 9--- :!ibio!ic (%ed a% a!i p%e(do"oa% aer()io%a>- a- Teropee" b- 3aci!raci c- :"o8icilli d- peicilli @ CDEFGDH IJEFKLGM NGODJKGM NJPLQ CDEFGDH IJEFKLGM NGODJKGM NJPLQ 2&(- .ntipseudomonal .ntibiotic :- <piperacillin;carbencillin;ticarcillin = 2&+-.u#liar of label are written on bo# contain :- T'%/6TUR.b,6 all is true e#cept:- a-%+a$e !+e bo!!le before (%e b-%(%pe%io c-freeCi) of dr() d-$eep o(! of reac+ of c+ildre 2&1-%pratropium bromide :-<.nti muscarinic bronchodilator =
9-9-$eep i cool place "ea% >- a-i refri)era!or b-i freeCi) c-a! 02-92 cl d-:^K e-:^3
2(2-.mphetamine act as :- <%73%'6:T-.:T%7" .3'676'"%: ."7%>T= 2(3-%ncrease plasma U3, ,evel :- <'educe 'isk of .therosclerosis = 2($-)araferin act as:- <inhibited blood clot = anticoagulant 2(&-cyclophosphamide side effect is:- a-blared ,i%io=44444 b-,o"i!i) &alopecia c-boe "arro; depre%%io d-:^3 e-3^K CDEFGDH IJEFKLGM NGODJKGM NJPLQ 2((-.ction of alpha 1 receptor:-BBBBBBB0 2(+-which of the drug used in open angel glaucoma:- <pilocarpine = 2(1-.ll <.:6%s= are prodrug e#cept:- :.@T@'%, <prototype= 2(5-pthalmic prep0 @roffered to be taken:- a-%ol(& m %(%p& m oi!& b-%ol(& m oi! m %(%p& c-%(%p& m %ol(& moi! d-a< do%a)e for" ca be (%ed 2+8-digo#in to#icity precipitated by : - <Uypokalemia = 2+1-which of the following drug has anti inflammatory effect :- <%buprofen = 2+2-3igito#ine effect in electro cardio chart <6:"=:- a-prolo) #&R b-%+or!e #&R
2+3-3igito#ine to#icity effect in electro cardio chart <6:"=:- a-prolo) #&R b-%+or!e #&R c- /& %+aped d-prolo) 3&R 2+$-'elative bioe4uivalent compared between std0 drug Stest drug acc0 To :- .`: <.rea `nder the :arve = 2+&-:ephalae#ine is :-first generation cephalosporin0 2+(-.fter the myocardial infraction we use :- .nti platelet <aspirin= CDEFGDH IJEFKLGM NGODJKGM NJPLQ 2+1-meprazol used for :- peptic ulcer 2+5-.lph 2 .gonist :- 3ecrease blood pressure 218-The e4uation that determine the acid S base degree is:- <T'76>T63 6a`.T%7 = 211-%>7%.b%36 used in T%T6':`,%> 0 212-mechanism of action of Tuspirone on:- >erotonin <&UT9a= receptor 213-.ll these cases not cure with thiazides e#cept:- a-+<pera!ri"ia b-.<per)l<ce"ia c-.<po$alae"ia d-.<er(ricea"ia e-.<poa!ri"ia 21$-)hich of the following drug of choice for /y#odema:- <Uypothyroidism = :-Thyro#in sod0 21&-!it0 . daily dose is 38;888-&8;888 %` for the correction of the deficiency Sfor therapy from 188;888-288;888 %`Vday0 21(- .ll these cases not cure with thiazides e#cept:- a-+<percalce"ia b-.<po)l<ce"ia c-.<po$alae"ia d-.<er(ricea"ia e-.<poa!ri"ia 21+-bidovudine is used for U%!0 211-Tisacodyl used as :- ,a#ative 215-@/ mean:- prescription only medicine CDEFGDH IJEFKLGM NGODJKGM NJPLQ 258-The con0 f the drug on e#p0 3ate is :- 2rom 58-118A 251->urfactant not used orally :- >od0 ,auryl >ulphate 252-The drug transfer through the cell membrane by :- a-:U(eo(% diff(%io b-H%"o!ic pre%%(re c-Pipid di%%ol,e d-#a%%i,e diff(%io e-GHG of !+e abo,e 253- :alcipotriol is indicated for :- @>'%.>%> 25$-which of the following make water retention:- <%ndomethazine= 25&-7itroglycerin is :- <!asodilatation of coronary artery=0 25(-.nti psychotic act as :- <3opaminergic .ntagonist = 25+- !it; X is antagonist of :- ).'.2.'%76 251-protamine sulphate is anti dote of:- U6@.'%76 255-@rmethazine used as :- .nti histaminic <pruritus ; cough ;anti emetic=
388- )hich f The 2ollowing act as alpha 1 blocker :- < @'.b:%7=0 382-6>/, is:- >hort acting T- blocker used in emergency in .cute arrhythmia as %! administration 0 383-which of the following has not effect on drug response:- a-nutrition b-genetic c-mental status d-age e-disease 38$-cyclizine used in :- a-nausea Svomiting b-antibiotic c-bronchodilator d-antihistaminic 38(-which of the following is not side effect of propantheline:- a-blurred vision b-dry mouth c-constipation d-bronchospasm e-urinary retention 38+-propencid increase the con0 f penicillin through :- a-increase renal tubular reabsorption b-decrease renal e#cretion c-decrease hepatic metabolism 381-one of the following not to#ic effect of methyl dopa:- a-sedation b-drug fever c-gangrene d-anemia e-hepatitis 385-patient take cisplatin should be taken with :- "ranisetron <anti emetic = 318-purified water can not used in:- a-ophthalmic preparation b-%! solution c-oral preparation d-oral suspension e-.ST CDEFGDH IJEFKLGM NGODJKGM NJPLQ 311-ascobic acid is :-< vit0 : = 312-/ecanism of action of Tri cyclic antidepressant:- >erotonin S 76 'euptake %nhibitor 313-%sopretrenol is :- a-alpha Sbeta agonist b-alpha blocker c- alpha agonist d-beta agonist e-beta blocker 31$-.ctive immunity can be conferred by :- a-anti to#in b-anti sera c-vaccine d-immuno bodies 31&-/echanism of action of echothiophate:- < 2orm stable comple# which cholinesterase enzyme = <%ndirect-.cting :holinergic .gonists = <.nticholinesterases Yirreversiblec = 31(- The latin abbreviation forYstatec:- <%mmediately =
31+- !olume of blood Vmint cleared through kidney called:- a-total body clerance b-renal clerance c-hepatic clerance d-BBBBBB0 311-ventami# is :- <bronchodilator= 315-3iltiazem not used in :- a-heart falier b-.ngina pectories c-Uypertention <UT7= d->. node block e- Ueadach
328-3rug used in 3iarrhea Sconstipation :- a-polycarbophil b-pictin c-senna d-BaSbBBB 321-.lpha blocker has side effect :- <postural Uypotention = 322-the dose of cefi#ime :- a-$88mg b-188mg c-1288mg d-1&88mg CDEFGDH IJEFKLGM NGODJKGM NJPLQ 323-the dose of asprin as antiplatelet:- a-18mg b-128mg ???????? c-2&8mg d-&88mg 32$-.lpha calcidiol can not used with patient:- a-liver dysfunction b-renal dysfunction 32&-co-trimetho#azol precentage of trimethoprim to sulphmetho#azol is : a-1:2 b-1:3 c-1:& d-1:18 32(-diazepam over dose ttt with:- <flumanzenil=
32+-Thephylline side effect is : a-skin rash b-insomnia d-BBB00 321-3ipivefrine is:- a-.nti UT7 b-chelating agent c-"lucoma
32- ,"i#" of t"e follo-ing .ot o##ur in digitalis to/i#ity:- a)hypokalemia b)hypomagnesia c)hypocalcemia d)hypothyroidism e)impaired kidney function.
??2-cla%% 7@ a!i arr+<!+"ia i% >- LverapamilM 330-Patient -"o is allergi# to peni#illins use:- a) claforan b)erythromycin c)cefotetan d)augmentin e)cephalexin. 332-!etra#aine used for:- a ) Spinal anesthesia b) opioid analgesic c) neuromuscular blocking agent d) vit d metabolite c) in treatment of Parkinsonism. 333- 1terility t"roug" .22 m filter2 do not remove:- A)bacteria b)virus c)fungi d) a+c e)b+c 33(-.ot used #lini#ally:- a) heroin b)morphine c)codeine d)oxycodiene hydro morphine. 333- ,"i#" in#rease t"e a#tion of morp"ine:- a ) vit k b)carbazepine c)amidarone d)contraceptive e)none of the above. ??1-%ide effec! of cla%% 9 a!iarr<!+"ic>- L bronchospasm M
334- 5n (+.&.6.) #ongestive "eart failure -e use digo/in to:- a) incr.myocardiac contraction b) in#rease myo#ardium e/#itability #) dec.myocardiac contraction d)77777777777777777 33-!"e least sedating:- a) iazepam b) chlorodiazepoxide e) probamate f) oxazepam g) buspirone ?B2-dr() o! decrea%e% P*P>- a=simvastatin b= clobifibrate c= nicotinamide d=propecol
!"#-$A%&'()(*+ (S S+%+,-(.+ +S-$&/+* 0&1%A-&$ ,&*-$A(*(,A-+ (* .- PA-(+*-2- 3 true) !"4-Promethasine is used for2- 3antihistamic) 3(3-,"i#" of t"e follo-ing .ot used in diagnosis of a#ute (8.5. ) myo#ardial infra#tion:- a)albumin b)signs and symptoms c)troponin. d) scurvy e) a5 d. 3((-+us"ing syndrome #aused by taking:- 0- /lucocorticoid drugs 5 4-tumor secret high cortisol level77 3(3-9.d.s. means to be taken " times daily. 3(:-;it A avoided in:- a) $ickets b) blindness c) pregnancy d) scurvy e) a 5d 3(7-,"i#" not effe#t of t"eop"illine:- a)preiphral vasoconistriction b)cardiac stimulation c)dieresis d)relax of stomach muscles e)stimulation of ,.*.S. 3(4-.ot e/pe#ted -it" in"aled smoke of #annabis:- a)increase pulse rate b)anorexia c)preceptal changes d)vascular changes of eye. 3(-Per#entage of -ater a##. !o body -eig"t is7..678 33)-.a pi#osulfate is used for 7laxative7.. 330-<opamine is used in #ardia# s"o#k as:- a) increase lung performance b) decrease ,.&.P. c) on9t induce preiphral vasoconistriction d) dec.force of contraction e) selective dilate renal 5 mesenteric 332- .erapamil #an in#rease effe#t of (theophylline 5 carbamazepne&digoxin7.) as a liver enzyme inhibitor
333-=sed in treatment of parkinsonism:-> a)amphetamine b)dopamine c)nicotine d)albuterol 33(-Aspartame is used as777s:eetener7 333- &ormone repla#ement t"erapy in all postmenopausal -omen :- a)true b) false 33:-Properties of #ate#"olamine:- a)rapid metabolism by A,;+. b)slo: metabolism by ache c)slo: ,&0- d)rapid metabolism by ,&0- and 0A&. ?-1-a!i+<per!e%i,e ac! a% alp+a 0 bloc$er i ar!er< ^ ,ei>- a=hydralazine b= mino#idil c=terazocin d=BB BB ?-D-bile acid %eU(e%!ra!%nij oip ?-9-:KE7% ^ :R3% r co!ra idica!ed i >- renal artery stenosis patient ?62-c<clo%erie (%ed i /&3 for +o; lo)WWWWW ?60- a!(ral ;a!er ca be (%ed i >- e#ternal preparation ?69-ideal ,ol("e of e<e %ol(!io>- a=&88micro b=&8-2&8 micro c=18-&8 micro d=Y18 micro ?6?-dipi,efree i%>- epinephrine analoug used in glaucoma ?6B-ido8r(bici i%:- antiviral for herpes simple# ?6--;+e p+ar"ac< o;er )i,e direc!io !o e"plo<ee i +i% p+ar"ac< !o "oi!or policie%^ re)(la!io i! i% > -a=danocratic b= democratic c= participation d=consultative 3((-.,, 2 TU6 2,,)%7" .:T%7 2 :.22.%76 6R:6@T:- .-:7> >T%/`,.7T :-3%`'6T%:> T->X6,6T., /`>:6,6 '6,.R.7T 3-:.'3%.: >T%/`,.7T 3(+-7%T' ",d:'%7 >%36 6226:T is:- .-tachycardia b-bradycardia c-BBBBBB 3(1-propranolol is:- <none selective b-blocker= 3(5-which of the following drug cause tachycardia:- a-propranolol b-atenolo :-hydralazin d-BBBBB 3+8-enkefaline as peptide used in :- a-electrical conduction as neuron transmitter b-similar in action to morphine d-BBBBBBBBBBBBBB CDEFGDH IJEFKLGM NGODJKGM NJPLQ 3+3-pento#ifylline use as :- a-peripheral vasoconstriction b-dry cough c-BBBBBBB0 3+$-the main site of e#ecration of the drug in the body is:- .-kidney b-liver :-stomach 3+&- clofibrate act as :- 1-decreas U3, 2-deacreas lipoprotein lipase 3-synthesis of cholesterol $-decreas lipoprotein
3+(-water used for reconstitution of large dose of parentral is:- a-sterile water for for injection b- water for injection b-distal water 3++-all of the following side effect of hydrocortisone e#cept:- a-7a retention b- glucose intolerance c-arthritis d- osteoporosis 3+1-reserpine side effect: a-parkinsonism b-depression c-BBBBBB0 379 - p; use to : a-determine acidity b- increase :ith basic c-for P&; CDEFGDH IJEFKLGM NGODJKGM NJPLQ 380 - +nzyme ,<- P"=7 discovered by -:
311- T% .!%,.T%,%Td /6.7 TU6 3'`" '6.:U: A-S(-+ &) A,-(&* >- >%&& ,($,1%A-(&* c ..- 312- )hich of the following drugs is a systemic amoebicide* a-3ilo#amide furoate b-@yrimethamine c-6metin d->odium >tibogluconate 313-)hich of following drugs is the drug of choice for the treatment of all forms of >chistosomiasis* a-@razi4uantel b-/ebendazole c-7iclosamide d-Thiabendazole 31$-)hich of the following drugs can be used for the treatment of influenza . infection * a-bidovudine<.bT= b-.mantadine c-'ibavarin d-!idarabine 31&-)hich of the following drugs is used in the treatment of ,eishmaniasis* a-@yrimethamine b-3ilo#amide c->odium >tibogluconate d-6metin 31(-.ll of the following preparations contain alcohol e#cept:- a->yrup simple# b-.romatic ammonia spirit `>@ c-Terpin hydrate eli#ir `>@ d-Telladona tincture T0@ 31+-)ich of the following solutions is used as an astringent* a->trong iodine soluotin `>@ b-.luminium acetate topical solution `>@ c-.cetic acid 72 d-Tenzalkonium chloride solution 72 CDEFGDH IJEFKLGM NGODJKGM NJPLQ 311-ane#trapyramidal adverse effects is caused by the blocking of:- a->erotonin receptors in the brain b-.cetylcholine receptors in the brain c-3opamine receptors in the brain d-3opamine receptors outside the brain 315-. rare side effect of some anticonvulsants is >tevens- Wohnson syndrome0this is a severe:- a->kin reaction b-Tone marrow to#icity c-'enal failure d-:7> suppression 358-)hich of the following are side effects of phenytoin treatment* a-.cne b-Uirsuitism c-"ingival hyperplasia d-a;b;and c 351-all factors affect on distribution of drug e#cept :- a-partition co-efficient b- 'ate of blood flow to tissue c- @U d- .ST e- TS: 352-)hich of the following is 7T betamethasone side effect * a-hypoglycemia b-skeletal muscle weakness c-sodium retention d-lowered resistance to infections 353-)hich of the following are causes of oedema* a-increase hydrostatic pressure b-decrease oncotic pressure c-increase capillary permeability d-all of the above 35$-.ll These are side effects of :hloramphenicol e#cept:- a- %rreversible a plastic anemia b- optic neuritis c- peripheral neuritis d- iron deficiency anemia CDEFGDH IJEFKLGM NGODJKGM NJPLQ 35&-Ticlopidine is used for :- a- .nticoagulant b- .ntibiotic c- anticholinergic d- .ntiplatelets 35(-.ll these drugs are fibrinolytic e#cept :- a- 3ipyridamole b- >teptokinase c- urikinase d- 776 35+-.ll These drugs cause anti-metabolic effect e#cept :- a- /ethotre#ate b- 2lurouracil :- :ytabrin e- :yclophosphamide 351-.ll These drugs can be used for @arkinsonism e#cept : a- >elgitine U:, b- :arbidopa c- @ergolide d- 7edocromil >od0 355-:ardiac arrest could be managed by the following e#cept :- a- 6phedrine b- ,%docaine c- @ropranolol d- 7ormal saline $88-%nsulin which can be given %0!0 is :- a- 'egular type b- 38V+8 type c- 7@U type d- 7on of the above $81-.ll These drugs are anti-bacterial e#cept :- a- balcitabine b- ,omeflo#acin c- :efprazone d- 7on of the above $82-.ll These are natural 6strogens e#cept :- a- /estronol b- estrone c- estriol d- estradiol CDEFGDH IJEFKLGM NGODJKGM NJPLQ $83-)hich one of the following has vasodilator effect :- a- 7icotine b- :holestyramin c- urikinase d- !it0 . $8$-ne of the following is not from auinolone group :- a- 7alidi#ic acid b- auinine c- 6o#acin d- 7orflo#acin $8&-ne of the following is not for 6pilepsy :- a- :lorizepam b- @henytoin c- @rimidone d- %mipramine $8(->umatriptan is used for :- a- Uypertension b- Treatment of migraine c- .ngina @ectoris d- :ontrol of 6pilepsy $8+-.ll of the following for prophyla#is of asthma e#cept :- a- Xetotifen b- 7edocromil >od0 c- >od0 :romoglycate d- >albutamol $81-.ll of the following is 7>.U e non sedating antihistamine f e#cept :- a- ,oratidine b- :etrizine c- .stemizol d- .zotodin $85-.ll of the following are controlled drugs e#cept : a- 'ivotril b- 6panutin c- >resolid d- 3iazepam $18-)hich one of the symptoms does not occur with morphine : a- 3iarrhea b- 'espiratory depression c- :onstipation d- !omiting CDEFGDH IJEFKLGM NGODJKGM NJPLQ $11-)hich one of these drugs is not used for acute pain :- a- 7apro#en b- b- :olchicine c- :odeine d- @rednisolone $12-Uepatitis !accine dose is : a- nce V year b- Twice V dear c- Three times V dear d-7one of the above $13-ne of the following is given once daily:- a- .morphous %nsulin b- @rotamine binc %nsulin c- 7eutral insulin d- 'egular %nsulin $1$-3obutamine is given %0!0 because :- a- %t is not stable in the gastric @U b- %t is needed in large 4uantities in case of oral route c- %t is eliminated very 4uickly d- 7one of the above $1&-.miloride as trimetren causes :- a- :7> disturbances b- Uyperkalamia c- Uypokalamia d- 7ot affect X e @otassium f $1(-:efaclor is : a- %st; "eneration :ephalosporin b- 2nd; generation :ephalosporin c- 3rd; generation :ephalosporin d- 7one of the above $1+-)hich .minoglycoside antibiotic can be taken orally * a- "entamycin b- 7eomycin c- .mikacin d- Tobramycin