Communicating (perforator) Veins Communicating veins (perforators) play an important role in the complex and varied hemodynamic states found in the leg. As the check-valves between the high-pressure deep and the low-pressure superficial systems, perforators activated by the muscle pump mechanism help maintain even and efficient evacuation of blood from the leg. Contraction of muscle bundles surrounding the deep fascial veins and perforators massages blood inward and upward, creating a pressure gradient that pulls blood from the superficial tributaries through the perforators into the deep system. Maintenance of this normal flow pattern is dependent on fragile valve leaflets present in each of the three anatomical components of the venous system in the leg. These leaflets, or cusps, are easily damaged, particularly by venous thrombosis. Approximately 30% of patients with varicose veins have incompetent perforators. 1 They are also implicated in exacerbating chronic venous disease and contributing to venous ulcerations. 2 In addition to valvular insufficiency secondary to venous thrombosis, clinical manifestations of chronic venous insufficiency may also appear with congenitally absent or malformed valves. In the lower extremity, there are numerous connections between the superficial and deep venous systems. These communicating veins frequently referred to in clinical practice as perforating veins perforate the muscular aponeuroses throughout the leg linking the two systems anatomically and hemodynamically. This linkage is a critical component of normal venous outflow from the leg. Perforators are found everywhere in the leg. Autopsy studies have revealed that each leg can contain as many as 80 140 communicating veins. They are disbursed topographically at the level of the ankle, calf, knee, thigh, and groin. Each vein contains at least 2 valves, that makes for a lot of perforator valves in the leg that can go bad and upset the normal venous hemodynamic relationships in the leg. Flow direction in normal communicating veins in the leg. Sonographic correlation. Normal perforator flow. ProSono copyright 2006 Perforator Veins of the Leg (14) Communicating veins have several configurations. Type I Single, direct connection between a deep and a superficial vein. Type II Several branches connecting two superficial veins to a single deep vein. Type III Two deep vein branches connecting to a single superficial vein. Type IV Ascending within the muscular compartments of the leg. ProSono copyright 2006 Perforator Veins of the Leg (15) General Topographical Anatomy There are several anatomical approaches to studying perforator veins in the leg. The topographical approach marks locations of communicating veins based on external leg landmarks using the popliteal space as a north-south boundary. Specific groups of veins found above and below the popliteal space are listed in Tables V and VI. Alternatively, communicating veins can be grouped into functional categories; those participating in hemodynamic equilibrium along the great saphenous and those along the short saphenous veins. Some anatomists make a distinction between communicating veins and perforator veins. They would categorize those veins that connect superficial vein to superficial vein as communicating veins and those that connect superficial to deep as perforator veins. The anatomical approach or taxonomic language a vascular ultrasound laboratory takes is less important than sharing that approach with the vascular surgeons and interventionalists who will be using the information to plan treatment for their patients. Table V. Communicating veins Above the Popliteal Space Connects External Landmarks Name Superficial Deep Upper 1/3 third of thigh Proximal terminal Terminal portion of the long saphenous Femoral vein Perineum Perineal Long saphenous trunk and its posterior branches via a Giacomini vein Uterine and ovarian veins of the hypogastric network Middle 1/3 of thigh Distal terminal Long saphenous network Femoral vein Lower 1/3 of thigh, adductor canal Dodd's Long saphenous network Femoral vein ProSono copyright 2006 Perforator Veins of the Leg (16) Typically, the diameter of a normal, competent communicating vein is <2mm, therefore, many of them are not routinely recognized during routine duplex imaging of the leg. They have to be searched for. With the highly sensitive Doppler imaging methods now in use, even normal perforators can frequently be found and evaluated. As one would expect, based on knowledge of myriad anatomical configurations, these veins have an equally varied sonographic appearance. Several observations on the size, appearance, and expected flow direction within perforator veins (PV) can help the vascular sonographer sort things out. Perforators less than 3 mm in diameter regardless of flow direction on color Doppler Imaging (CDI) are probably normal. 3 Vein diameter >3.9 mm = 95% chance of valvular incompetence. PV incompetence is most often associated with reflux in the superficial veins. 4 Incompetent PVs have outward flow alone (77%). 5 6 When ultrasound system levels and examination protocols are optimized to evaluate perforator veins, the accuracy of triplex imaging is equal to that of contrast venography without the potential risks. Low-threshold, low velocity flow detection should be maximized for CDI of perforator veins. Flow direction can be more easily be determined and documented using CDI, however, the operator must be well versed in CDI interpretation. 7 Table VI. Communicating veins Below the Popliteal Space Connects External Landmarks Name Superficial Deep Medial subcondylar region Boyd's Saphenous network of the subcondylar region Popliteal or tibioperoneal trunks Heads of gastrocnemius muscles Medial gastrocnemius Saphenous network around knee Gastrocnemius veins Medial supramalleolar region Cockett's Posterior saphenous branches Posterior tibial veins Lateral lower calf Peroneal Anterior saphenous branches Peroneal veins Retromalleolar and submalleolar regions Saphenous and marginal branches Plantar veins ProSono copyright 2006 Perforator Veins of the Leg (17) Clinical Anatomy The ones of most frequent locations of clinical manifestations of perforator vein incompetence, especially in the setting of concomitant superficial venous insufficiency, is an area along the medial, distal calf. Coursing beneath the superficial fascia are a series of veins, usually six in number, that join the posterior tibial vein to the greater saphenous system. These stubby communicating veins are known as Cocketts perforators and are found along the medial-posterior aspect of the tibial crest. They course through the deep fascia of the calf connecting the deep tibial veins to the great saphenous vein through a series of interconnected posterior arch veins. There are usually three sets of Cocketts perforating veins (labeled 1, 2, and 3 in the schematic) and they lie between 10 15 cm above the lower margin of the medial malleolus. Insufficient Cockett perforators are usually easily demonstrable with duplex ultrasound and frequently can be palpated with the fingertips as indentations, or divits along the tibial crest. Commonly, in patients with stasis changes in the ankle, the area most obviously affected lies directly above an incompetent perforator vein. Using these clinical pearls can help the vascular sonographer localize the level and number of incompetent perforator vein before beginning the duplex examination. 2-D sonographic image of a dilated, incompetent medial tibial perforator vein. PTV: post. Tibial v. VV: varicose GSV tributary CDI demonstration of perforator incompetence. With compression of the calf, blood refluxes out of the PTV and into a perforator vein ProSono copyright 2006 Perforator Veins of the Leg (18) 1 Wills V, Moylan D, Chambers J. The use of routine duplex scanning in the assessment of varicose veins. Aust N Z J Surg. 1998 Jan; 68(1):41-4. 2 Labrpoulos N, Leon M, Geroulakos G. et al. Venous hemodynamic abnormalities in patients with leg ulceration. Am J Surg. 1995 Jun; 169(6):572-4. 3 Phillps GW, Cheng LS. The value of ultrasound in the assessment of incompetent perforating veins. Australas Radiol. 1996 Feb; 40(1):15-8. 4 Stuart WP, Lee AJ, Allan PL, et al. Most incompetent calf perforating veins are found in association with superficial venous reflux. J Vasc Surg. 2001 Nov; 34(5):774-8. 5 Labropoulos N, Mansour MA, Kang SS, et al. New insights into perforator vein incompetence. Eur J Vasc Endovasc Surg. 1999 Sep; 18(3):228-34. 6 Delis KT, Husmann M, Kalodiki E, et al. In situ hemodynamics of perforating veins in chronic venous insufficiency. J Vasc Surg. 2001 Apr; 33(4):773-82. 7 Meyer T, Cavallaro A, Lang W. Duplex ultrasonography in the diagnosis of incompetent Cockett veins. Eur J Ultrasound. 2000 Jun; 11(3):175-80.