WOUND HEALING DRUGS FORM MEDICINAL PLANTS

Dr. S. GOPALA KRISHNAN.

Senior Professor of Chemistry & Controller of Examinations,
Noorul Islam University,
Kumaracoil 62 !"#
K$K$%istrict, &amil Na'u$
Email(s)*msu+yahoo$co$in
ABSTRACT
,oun' care can -e trace' -ac* to early civili.ations an' many of these treatments
/ere -ase' on the use of her-al reme'ies$ 011roximately one thir' of all the tra'itional
me'icine in use is for the treatment of /oun's an' s*in 'isor'ers, com1are' to only !234
of mo'ern 'ru)s$ 5e'icinal 1lants have -een use' since time immemorial for the
treatment of various ailments of s*in an' 'ermatolo)ical 'isor'ers es1ecially cuts,
/oun's an' -urns$ 6ealin) of /oun's is an im1ortant area of clinical me'icine ex1laine'
in most of the 0yurve'ic texts un'er the hea'in), 78ranaro1a*a9$
Current estimates in'icate that nearly 6 million 1eo1le suffer from chronic
/oun's /orl' /i'e$ &here are only very fe/ In'ian stu'ies on the e1i'emiolo)y of
chronic /oun's$ &he 1revalence of chronic /oun's in the Community /as re1orte' as
:$; 1er !### 1o1ulation /here as that of acute /oun's /as nearly 'ou-le' at !#$; 1er
!### 1o1ulation$
0 /i'e ran)e of anti-iotics is -ein) use' at 1resent for treatin) /oun'
infections$ <ut they are no/ 1rove' to have a'verse si'e effects such as liver 'ama)e,
liver failure an' miner si'e effects such as hea' ache, stomach u1set, 'iarrhea, itches an'
rashes in human -o'y$ 0lso these 1atho)ens 'evelo1e' resistance to the anti-iotics
tar)ete' a)ainst them$ Si'e effects associate' /ith allo1athic 'ru)s an' synthetic
com1oun's, has 1rom1te' research into her-al an' natural 1ro'ucts for /oun' healin)$
0 lar)e num-er of 1lants, 1lants extracts, 'ecoctions an' 1astes are e=ually use' -y &ri-al
an' >ol*lore tra'itions in In'ia for treatment of cuts, /oun's an' -urns$
In the 1resent investi)ation, the in viva /oun' healin) activity stu'ies of the
ethanolic extracts of four me'icinal 1lants, Viz; Bauhinia tomentosa ?$ @<ar*A
Mussaenda frondosa ?$@,hole 1lantA Acalypha fruticosa >ors*$ @0erial PartsA an'
Dipteracanthus patulus @Bac=A Nees$@?eavesA have -een 1erforme' usin) 'ifferent
ex1erimental animal mo'els such as excision, incision and dead space mo'els$
6isto1atholo)ical stu'ies of the )ranulama tissue have also -een 1erforme'$ &he results
in'icate that all the four me'icinal 1lants have very )oo' /oun' healin) activity$ &hese
1lants satisfy the criteria of the /oun' healin) a)ents -y increasin) the rate of contraction
of /oun', /ei)ht of )ranulation tissue, tensile stren)th of )ranulation tissue an'
formation of colla)en$ &he fin'in)s /ill -e 'iscusse' in 'etail$

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