Gingival hyperplasia in a patient treated with calcium channel blocker.
In additional in local complications, periodontal disease may have systemic consequences. Bacterial respiratory tract pathogens colonize dental plaque and are believed to contribute to pulmonary infections and exacerbations of chronic obstructive pulmonary disease through aspiration, generation of cytokines, and alterations in the antibacterial properties of saliva. In patients in intensive care units, this colonization has been prospectively linked to the development of nosocomial pneumonia and bacteremia. Further research is needed to determine whether improved oral health and reduction in the presence of pathogenic oral bacteria can reduce the risk of respiratory tract infection in high-risk patients. Recently, much attention has been given to the possible relationship between periodontitis and the development of atherosclerosis. This was postulated after showing that bacterial species such as porphyromonas gingivalis can activated thrombotic pathway and that periodontal infections are associated with release with release of cytokines and other inflammatory mediators. Although some studies have shown an increased risk of subclinical atherosclerosis and coronary artery disease in persons with periodontitis, treatment of periodontal disease has not yet been proven to reduce the incidence or severity of these conditions. Edentulous persons An important predictor of health is the retention of natural teeth with age. In 1993, however 33% of americans over the age of 65were edentulous , and only 16% these person visited a dentist. Physicians may, therefore, play an important role in the oral health of edentulous, persons. The loss of natural teeth affects the ability to eat, speak, and chew , and may lead to costly restorative and rehabilitative care. Dental caries and periodontal disease cause the majority of tooth loss, though other causes include trauma and complications from treatment of oral cancer. Disabilities that result from tooth loss may not be reversible, even with proper-fitting dentures. Tooth loss is considered largely preventable through education, personal hygiene dental care, and community preventive measure such as water fluoridation. One option to replace lost teeth is the use of dental implants. These contain a titanium serew and are permanently osseointegrated into alveolar bone. Full dentures or single tooth units are then attached for cosmetic and functional purpose. Removable dentures made of acrylic resins are less expensive and are more commonly used. The preparation of any prosthetic device may be complicated by anatomic considerations, comorbid illnesses, and medications side effects. Although stability and alignment of the prosthesis are important, denture s may be rejected by