Professional Documents
Culture Documents
+
X
]
-X
Z
]
-Z
(Z
c
Z
) (2)
c
=
+
Y
]
-Y
Z
]
-Z
(Z
c
Z
) (3)
3628 M. Giri Vivek Narayan, N.S. Manigandan, S. Rakesh Kumar
Fig.4 contour for the blue colored region (i.e.) less oxygenated region
2.4 THRESHOLDING
After getting concluded from the contour that there are different intensity levels exist
within the region of interest which is separated using image segmentation technique
color segmentation method, it is understood that it is feasible to analyze the affected
region based on the oxygen variation which is proportional to the intensity variation
in the pixels of the image. So on an user defined threshold valuesare used in this paper
to classify the region of interest areas in such a way that the threshold will lead to
select the particular pixels which is greater than the given threshold which is
proportional to the amount of radiation which is again proportional to the oxygen
levels in varies places.
2.5 RESULTS AND DISCUSSIONS
It is shown that on varying the threshold level gives the oxygen variation in the
regions of our body through the image taken; various threshold levels and its results
for the less oxygenated regions are discussed from Fig.5.(a) to Fig.5.(e) and more
oxygenated region are discussed from Fig.6.(a) to Fig.6.(d).
Analysing the Oxygen Variation by Image Processing Technique 3629
(a) (b)
(c) (d)
(e)
Fig.5 (a) shows region bounded for threshold value T=0.5, (b) shows region bounded
for threshold value T=0.75, (c) shows region bounded for threshold value T=0.9, (d)
shows region that are in between T=0.75 to T=0.9 alone by subtracting 5 (b) and 5 (c),
(e) shows the region that are in between T=0.5 to T=0.75 by subtracting 5 (a) and 5
(b).
Blue color regions are less oxygenated and in the Fig.5.(a)Cover the entire less
oxygenated area when a less threshold is kept (T=0.5), Fig.5.(b) shows only the
regions with very less oxygen level and is covered by the red color boundary line
these regions are got by increasing the threshold level to a medium range (T=0.75),
Fig.5.(c) shows least oxygenated regions covered by the red color boundary when
high threshold is given (T=0.9). It is clear from the above results that on increasing
the threshold for the pixels in the image the boundary that covers the region decreases
and traces regions where oxygen level are getting decreased. This is also verified by
taking the contour of the blue region where the different oxygen levels.
3630 M. Giri Vivek Narayan, N.S. Manigandan, S. Rakesh Kumar
To get the exact regions that is very less oxygenated we are using two different
color boundaries to separate the regions of least oxygenated from very less
oxygenated region, so the region between the yellow and red region is what the
regions in between the threshold levels of T=0.75 to T=0.9 which is shown in
Fig.5.(d). Similarly the regions which are in between the threshold levels of T=0.5 to
T=0.75 can be found as shown in Fig.5.(e) which is differenced by the red and yellow
color boundaries which represents the entire less oxygenated region and very less
oxygenated region. So on reducing the threshold the entire less oxygenated regions
are covered by the boundary line, similarly on increasing the threshold the least
oxygenated regions are only covered by the boundary line. As normalization is done
these threshold values can be used from 0 to 1 only.
In hypothyroidism image the red color segmentation is done to separate only the
thyroid regions which are emitting more IR radiation as shown in Fig.6.(a) then the
threshold classified regions for three values of T=0.5, T=0.75, T=0.9 images are
shown in Fig.6.[(b)(c)(d)] respectively. Fig.6.(b) shows the highest oxygenated
regions alone, Fig.6.(c) shows higher oxygenated region and Fig.6.(d) shows the
entire high oxygenated regions.
(a) (b)
(c) (d)
Fig.6 (a) shows the color segmented image of Red color alone (b) shows region
bounded for threshold value T=0.9, (c) shows region bounded for threshold value
T=0.75, (d) shows region bounded for threshold value T=0.5.
Analysing the Oxygen Variation by Image Processing Technique 3631
3. CONCLUSION
Obtained results show that analyzingthe oxygen level variation is possible to obtain
from the Infrared Images by processing it. Threshold values can also be kept constant
to make the analysis for various diseases; the images are taken from many samples
under same environment and with same camera with same operating frequency from
which it is possible to find the severity of a disease, healing process of the fire burns
or wounds. Prognosis of a disease can also be done with this analyzed data.
4. ACKNOWLEDGMENT
I would like to thank Martin Mohrke, Europe Resource Coordinator, Foundation for
Alternative and Integrative Medicine (FAIM) for making the test images online.
5. REFERENCES
[1] AhmadSalmanOgli and Ali Rostami, Modeling and Improvement of Breast
Cancer Site Temperature Profile by Implantation of Onion-Like Quantum-Dot
Quantum-Well Heteronanocrystal in Tumor Site, Nanotechnology, IEEE
Transaction, vol. 11, pp. 1183 1191, Nov. 2012.
[2] J. El Hazzat and M. E. H. El-Sayed, Advances in targeted breast
cancertherapy, Current Breast Cancer Rep., vol. 2, pp. 146151, 2010.
[3] Ojica, S.Iftemie, A.;Rau, M.C.;Costandache, D.;Baltag, O.,Microwaves and
infrared thermography Comparative studies in early breast cancer detection,
Advanced Topics in Electrical Engineering (ATEE), 2011 7th International
Symposium, pp. 1 4, May.2011.
[4] Rusnani, A. andNorsuzila, N. ,Measurement and analysis of temperature rise
caused by handheld mobile telephones using infrared thermal imaging,RF and
Microwave Conference, pp. 268 -273,Dec2008 .
[5] Sim, S.Y.Lee, W.K.;Baek, H.J.;Park, K.S.,A nonintrusive temperature
measuring system for estimating deep body temperature in bed, Engineering in
Medicine and Biology Society (EMBC), pp.3460 3463, Aug. 28 2012-Sept. 1
2012.
[6] Pan, L, Amory, D.;Li, J.K.-J.;Kalatzis-Manolakis, E.S,An improved design of a
noninvasive near-infrared brain oxygenation monitor, Bioengineering
Conference, pp. 31-32Mar 1993.
[7] Benaron, David ALenox, Marlo;Goheen, Matthew;Stevenson, David
K,Noninvasive measurement and imaging of tissue structure and oxygenation
using infrared time-of-flight absorbance (TOFA) spectrophotometry,
Engineering in Medicine and Biology Society, vol. 6, pp.2404-2406, Oct. 29
1992-Nov. 1 1992
[8] Benni, P.B.BoChen;Amory, D.;Li, John K-J ., A novel near-infrared
spectroscopy (NIRS) system for measuring regional oxygen
saturation,Bioengineering Conference, pp. 105 107, May 1995.
3632 M. Giri Vivek Narayan, N.S. Manigandan, S. Rakesh Kumar
[9] HamedAkbari, Yukio Kosugi, Kazuyuki Kojima, and
NaofumiTanaka,Detection and Analysis of the Intestinal Ischemia Using
Visible and Invisible Hyperspectral Imaging, IEEE Transactions On
Biomedical Engineering, Vol. 57, AUGUST 2010.
[10] T. O. McBride, Spectroscopic reconstructed near infrared tomographicimaging
for breast cancer diagnosis, Ph.D dissertation, Dartmouth College,Hanover,
NH, 2001
[11] Zh. Guoa, S. K. Wana, D. A. Augustb, J. Yingd, S. M. Dunne, and J.L.
Semmlow, Optical imaging of breast tumor through temporal
logslopedifferencemappings, Comput. Biol. Med., vol. 36, pp. 209223,2006
[12] A. Corlu, R. Choe, T.Durduran,M.A. Rosen,M. Schweiger, S. R.Arridge,M. D.
Schnall, and A. G. Yodh, Three-dimensional in vivo fluorescencediffuse
optical tomography of breast cancer in humans, Opt. Express,vol. 15, pp.
66966716, 2007.
[13] J. Kwok and J. Krzyspiak, Thermal imaging and analysis for breasttumor
detection, Comput.Aided Eng.: Appl. Biomed.Process., BEE 453,2007
[14] D. C. Kellicut, J. M. Weiswasser, S. Arora, J. E. Freeman, R. A. Lew,C.
Shuman, J. R. Mansfield, and A. N. Sidawy, Emerging
technology:Hyperspectral imaging, Perspect. Vasc. Surg. Endovasc. Ther., vol.
16,no. 1, pp. 5357, Mar. 2004.
[15] L. Khaodhiar, T. Dinh, K. T. Schomacker, S. V. Panasyuk, J. E. Freeman,R.
Lew, T. Vo, A. A. Panasyuk, C. Lima, J. M. Giurini, T. E. Lyons,and A. Veves,
The use of medical hyperspectral technology to evaluatemicrocirculatory
changes in diabetic foot ulcers and to predict clinicaloutcomes, Diabetes Care,
vol. 30, no. 4, pp. 903910, Apr. 2007.
[16] L. C. Cancio, A. I. Batchinsky, J. R. Mansfield, S. Panasyuk, K. Hetz,D.
Martini, B. S. Jordan, B. Tracey, and J. E. Freeman, Hyperspectralimaging: A
new approach to the diagnosis of hemorrhagic shock, J. Trauma-Injury Infect.
Crit. Care, vol. 60, pp. 10871095, May2006.
[17] J. E. Freeman, S. Panasyuk, A. E. Rogers, S. Yang, and R. Lew, Advantagesof
intraoperative medical hyperspectral imaging (MHSI) for theevaluation of the
breast cancer resection bed for residual tumor, J. Clin.Oncol., vol. 23, Jun.
2005.