Drug Name (Dose and Route) Mode of Action Indication Adverse Reaction Nursing

Consideration
Contraindication
Generic Name: Carvedilol
Brand Name: Dilatrend
Drug Class:
Antihypertensive


Dose:6.25mg/tab tab
Route:Oral








Decreased heart
rate and pulse
pressure.

Essential
hypertension;
CHF.
Fatigue
Dizziness
Bradycardia
CHF
Pulmonary
edema
Hypotension
Constipation
Impotence

Monitor BP
and pulse
prior and
throughout
therapy.
Take apical
pulse, if less
than 50 bpm,
withhold
medication
and notify
physician.
Advise
patient for
proper diet,
regular
exercise, and
lifestyle
modification.
Diabetics
should
closely
monitor
blood sugar.

Diseases that
constrict the
respiratory tract
(bronchial asthma,
chronic bronchitis,
pulmonary
emphysema),
allergic rhinitis,
swelling of the
laryngeal mucosa,
sinus node
syndrome, SA
block, 2nd & 3rd
degree AV block,
too slow heart rate,
shock, MI w/
complications,
severe liver
dysfunction,
metabolic acidosis,
or simultaneous
MAOI therapy.




Drug Name (Dose and Route) Mode of Action Indication Adverse Reaction Nursing
Consideration
Contraindication
Generic Name:Omeprazole
Brand Name: Tansinel
Class:Antisecretory drug
Dose:40mg
Route:IV
Gastric-acid pump
inhibitor:
suppresses gastric
acid secretion by
specific inhibition
of the hydrogen-
potassium ATPase
enzyme system at
the secretory
surface of the
gastric parietal
cells; blocks the
final step of acid
production.
Short-term
treatment of
active duodenal
cancer

Short-term
treatment of
active benign
gastric ulcer

Eradication of
Helicobacter
Pylori

First-line therapy
for treatment of
heartburn or
symptoms of
GERD.
CNS; headache,
dizziness, asthenia,
vertigo, insomnia,
apathy, anxiety,
paresthesias, dream
abnormalities

Dermatologic: rash,
inflammation,
urticaria, pruritus,
alopecia, dry skin

GI: diarrhea,
abdominal pain,
nausea, vomiting,
constipation, dry
mouth, tongue
atrophy

Respiratory: URI
symptoms, cough,
epistaxis
Assessment:
1. History
:hypersensitivity to
omeprazole or any of
its components;
pregnancy, lactation
2. Physical: skin
lesions; reflexes;
urinary output;
abdominal
examination;
respiratory
auscultation
Interventions:
1. Administer before
meals.
2. Administer antacids
with, if needed.
3. Have regular
medical follow-up
visits.
4. Report severe
headache, worsening
of symptoms, fever,
chills.

Contraindicated
with
hypersensitivity to
omeprazole or its
components.

Use cautiously
with pregnancy,
lactation.


Drug Name (Dose and
Route)
Mode of Action Indication Adverse Reaction Nursing
Consideration
Contraindication
Generic Name:
Methimazole
Brand Name: Tapazole
Class:Antithyroid Drug
Dose:5mg tab
Route:Oral
Directly interferes
with thyroid
synthesis by
preventing iodine
from combining
with thyroglobulin,
leading to
decreased thyroid
hormone levels

Hypersensitivit
y to drug
Breastfeeding
CNS: headache,
vertigo, paresthesia,
neuritis, depression,
neuropathy, CNS
stimulation GI:
nausea, vomiting,
constipation,
epigastric distress,
ileus, salivary gland
enlargement, dry
mouth, anorexia GU:
nephritis Hematologic:
thrombocytopenia,
agranulocytosis,
leukopenia, aplastic
anemia Hepatic:
jaundice, hepatic
dysfunction, hepatitis
Metabolic:
hypothyroidism
Musculoskeletal: joint
pain, myalgia Skin:
rash, urticaria, skin
discoloration, pruritus,
erythema nodosum,
exfoliative dermatitis,
abnormal hair loss
Other: fever,
lymphadenopathy,
lupuslike syndrome
Check for
agranulocytosis in
patients older than age 40
and in those receiving
more than 40 mg/day.
Assess hematologic
studies. Agranulocytosis
usually occurs within first
2 months of therapy and
is rare after 4 months.
Monitor thyroid function
tests periodically. Once
hyperthyroidism is
controlled, elevated
thyroid-stimulating factor
indicates need for dosage
decrease. Assess liver
function tests and check
for signs and symptoms of
hepatic dysfunction.
Monitor patient for fever,
sore throat, and other
evidence of infection as
well as for unusual
bleeding or bruising.
Assess patient for signs
and symptoms of
hypothyroidism, such as
hard edema of
subcutaneous tissue,
drowsiness, slow
mentation, dryness or loss
of hair, decreased
temperature, hoarseness,
and muscle weakness.
Contraindicated
with
hypersensitivity
to methimazole
or its
components.
Use cautiously
in:
bone marrow
depression
patients older
than age 40
pregnant
patients.

Drug Name (Dose and
Route)
Mode of Action Indication Adverse Reaction Nursing
Consideration
Contraindication
Generic Name:
Levofloxacin
Brand Name: Lovox
Class:Antibiotic Drug
Dose:500mg OD
Route:IV
Levofloxacin is an
antibiotic that stops
multiplication of
bacteria by
preventing the
reproduction and
repair of their
genetic material,
DNA.
*Myasthemia
gravis
The most frequently
reported side events of
levofloxacin
are nausea or vomiting
, diarrhea, headache,
and constipation. Less
common side effects
include difficulty
sleeping, dizziness, ab
dominal
pain,rash, abdominal
gas, and itching.
Rare allergic reactions
have been described,
such
as hives and anaphyla
xis(shock).
Hypersensitivity to
Levofloxacin or any
of its components;
pregnancy, lactation

Contraindicated
with
hypersensitivity
to Levofloxacin
or any of its
components.