Webinar series 2013:

Biotech Destination India: Opportunities & Challenges

Dr. Geetha M Swamilingiah
New Delhi, 26-03-2013
www.ebtc.eu
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Webinar series 2013:
Biotech Destination India: Opportunities & Challenges

Speaker Profiles
Dr. Geetha Swamilingiah | Biotech Sector Specialist, EBTC
Geetha has over 17 years of experience spanning from academic to Industrial
set ups in Biotech field be it Research & Development, product
commercialization, technology transfers and techno commercial activities over
wide subsectors of biotechnology. She also has number of international
publications and product patents to her records
Mr. Amitesh Suman|
Senior Manager, Operations and Business Development, ABLE, India
Amitesh has over 10 years of experience in Biotechnology Research and
Business. He has worked in science & Innovation projects and partnering
and/or out-licensing products and technology developed by the company and in-
licensing products and technologies that fit strategic and development
objectives. Building Business Models for various Biotechnology services
especially OMICs. Identification and evaluation of Business opportunity for
specific CRO/CMO. He also has patents and publications to his records

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Mr. Siddharth Dhodi
Manager, Life sciences Knowledge Banking, YES BANK LTD.,

Siddharth Dhodi is part of the Life-sciences team at YES BANK. The life-
sciences team is involved in entrenching the Banks Life-sciences portfolio. In
previous he was part of the Strategy and Business development team of TATA
groups drug discovery venture Advinus Therapeutics and Bigtec Labs, a
Technology led Medical device startup company and has lead its Government
Investment Initiative.

Siddharth is a Biochemical Engineer from HBTI Kanpur and an MBA from
Indian Institute of Sciences Bangalore.















Webinar series 2013:
Biotech Destination India: Opportunities & Challenges

Speaker Profiles
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Agenda
About EBTC
Indian Biotech 2013
Indian Life Science Industry - An Investment Perspective
EBTC services & activities in Biotechnology
Conclusion
Q & A
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About EBTC
4 locations across India: New Delhi (HQ), Mumbai, Bengaluru and Kolkata
4 core sectors: Biotech, Energy, Environment and Transport
4 steps from visibility to incubation:
Promoting Europe in India and India in Europe
Providing information and intelligence
Supporting the market entry process from the scratch
Providing full service, incubation, support for businesses and R&D
Working in partnership:
Consortium partners give access to SMEs and knowledge institutions e.g. Fraunhofer Institute,
Danish Technological Institute, IVL Swedish Environmental Research Institute, and more
Shareholder partners include Euro-India Research Centre, European Business Group India,
European Renewable Energy Council, The Council of EU Chambers of Commerce in India,
and more
Supporting technology transfer from the research stage up to the
product/ service launch in the Indian market.
Technical expertise in sunrise sectors with wide geographical coverage
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Biotechnology Segment Share
6
CAGR: 23.8%
Bio-Pharma: Therapeutic or preventative medicines that are derived from materials
naturally present in living organisms, using recombinant DNA (rdna) technology
Bio-Services: Include clinical research and CRO along with custom manufacturing
Bio-Agri: Segmented into hybrid seeds, transgenic crops, bio-pesticides and bio-
fertilizers
Bio-Industrial: Predominantly comprises enzyme manufacturing and marketing
companies
Bio-Informatics: Deals with the creation and maintenance of extensive electronic
databases on various biological systems; it is the smallest part of the current
domestic biotechnology industry
Low
High
G
r
o
w
t
h

o
v
e
r

n
e
x
t

5

y
e
a
r
s

Bio-
Services
Bio-
Pharma
Bio-Agri
Hybrid
Seeds
Bio-
fertilizers
Bio-
pesticides
High Low
Market Share
Bio-
Industrial
Bio-fuel
Bio-Plastic
Bio-Catalyst
Bio-Informatics
Indian Scenario
CAGR: 10.5%
Biotechnology Revenues, $bn Biotechnology Revenues, $bn
Biotechnology By Segment
2009-10
2009-10
Biotechnology By Segment
EU v/ s India Comparison
EBTC Webinar Series 2013: Wastewater as a resource: A lifecycle assessment
INDIAN BIOTECHNOLOGY 2013
Session-1
Mr. Amitesh Suman
Senior Manager, Operations and Business Development
ABLE

Content
Advantage India
Market overview and trends
Growth Drivers
Success Stories: BIOCON
Opportunities






Market overview and trends

GROWTH DRIVERS
SUCCESS STORIES:BIOCON
OPPORTUNITIES
EBTC Webinar Series 2013: Wastewater as a resource: A lifecycle assessment
Indian Life sciences Industry - An I nvestment Perspective
Session-2
Mr. Siddharth Dhodi
Manager, Life sciences Knowledge Banking
YES BANK LTD.
Strictly Confidential
Indian Economy: Overview
Demographic Indicators:
Total population of 1.2 billion; 31% in
the 0-14 years age group and 64% in
15-64 years.
30% of population is urbanized

Health Indicators:
GDP spend on health care in India
was a mere 1.1% in 2010.
Life expectancy increased to 64 years
in 2009, from 49 years in 1970.


0
1000
2000
3000
4000
5000
6000
7000
8000
2005-06 2006-07 2007-08 2008-09 2009-10 2010-11
G
D
P

(
i
n

I
N
R

t
h
o
u
s
a
n
d

c
r
o
r
e
)

India's GDP Growth: 2005-2011
Source: RBI
Economic Indicators:
Indias GDP more than tripled since 2000.
Indian economy is expected to be four times of
what it was in 2007, by 2020.
Exports increased by 38% in FY11 to reach USD
246 billion.

Strictly Confidential
Evolution of Indian Life Science Industry
The Indian Pharmaceutical industry has greatly evolved over the last 50 years.
India has proven its strength and capabilities in the areas of manufacturing, drug discovery and
generics.
The domestic industry is now moving into the phase of innovation, with the large and smaller niche
players, focusing on strengthening their research and drug development capabilities.
Life Science industry has become a crucial foreign exchange earner for the country
Strictly Confidential
Growth of the Indian Life Science Segments
Source: Yes Bank CII: Financing Ecosystem Report, 2011
Strictly Confidential
Opportunities for India in Life Sciences
80
140
0
20
40
60
80
100
120
140
160
2009 2015
U
S
D

B
i
l
l
i
o
n

Global Generic Market: 2015
CAGR: 10%
25%
15%
20%
55%
15% 15%
Discovery API Dev. Dosage
Dev.
API Manu. Dosage
Manu.
Packaging
Extent of Outsourcing in the Pharma Value
Chain
Source: Yes Bank; ICRA
Global Big Pharma companies are facing
high patent expirations, with drugs worth
USD 150 billion going off patent in the
2010-2015 period, thus they are
increasingly looking at the generics
segment.
India constitutes around 8% of total global
generic market, by volume, indicating a
huge untapped opportunity.
For global companies looking to
economize, outsourcing to lower cost
economies results in a cost-arbitrage of
more than 50%.
India adopted the product patent regime in
2005.
India has the second highest number of US
FDA approved plants, after only the US.
Outsourcing to India is projected to spike
up for the discovery and manufacturing of
formulations.
Strictly Confidential
Indian Biotech Sector
2.7
4.8
8
0
1
2
3
4
5
6
7
8
9
2008-09 2011-12 2014-15
U
S
D

B
i
l
l
i
o
n

Indian Biotech Industry by 2015
The Indian Biotech industry has seen
high growth with a CAGR in excess of
20%.
The key drivers for growth on the
biotech sector are increasing
investments, outsourcing activities and
exports.
Several newer sub-segments of the
sector like Bio-services, Bio-agri, Bio-
industrials are especially poised for high
growth in the near future.
With the Govt.s focus on the sector and
Indias growing capabilities, this sector
is poised to become a world leader.
Some major Biotech MNCs which have
set up their operations in India include
Amgen, UCB , Biogen Idec, Genzyme ,
Nektar, etc.
1900, 62%
580, 19%
410, 13%
120, 4%
50, 2%
Biotech Sectors: 2009-10
Biopharma
Bio-Services
Bio-Agri
Bio-Industrials
Bio-Informatics
Strictly Confidential
Government Support for the Indian Biotech
Industry
Some of its activities include:
Funding ideas through the
Biotechnology Ignition Grant
(BIG) scheme.
Establishing the early POC
through Small Business
Innovation Research
Initiative (SBIRI).
Taking the products to market
through Biotechnology
Industry Partnership
Programme (BIPP).

Department of Biotechnology is actively trying to promote R&D and funding high-risk projects
since its inception.
India's recently approved National Biotechnology Development Strategy (NDBS) includes a
strong focus on science education and training; increasing R&D funding; creating regional centers
of excellence.
Strictly Confidential
Investments in Life Science
For the Life Science industry,
especially for segments like
Biotech and Medical Devices,
early stage equity funding is
crucial due to the nature of the
business.
Other sources of funding
include:
Equity funding
Corporate partnering
Government support
Debt funding
M&A
Biotech sector requires a lot of
angel investments and venture
capital, but this early-stage
funding is especially challenged
due to the perceived high risk
and long gestation period
prevailing in this sector.
The challenge is to identify
good companies with the
potential to outperform.
0
2
4
6
8
10
12
14
FY08 FY09 FY10 FY11
PE Investments in Life Science Segments by Volume
Pharmaceutical Biotech Medical Device
CRO Diagnostics
53%
22%
16%
5%
2%
2%
PE Investgment in Life Sciences Segments
by Value
Pharmaceutical
Diagnostics
CRO
Biotech
Medical Devices
Others
Strictly Confidential
Joint International funding routes
Bilateral Cooperation
Indo-Spanish J oint Funding : J oint DBT CDTI Call for Proposals

DBT-BBSRC joint call in Crops Genomics and Technologies

Indo-Swiss Collaboration in Biotechnology (ISCB) : Food Security

Indo-Swedish Cooperative Innovation Programme (DBT- SRC)





*Biotechnology and Biological Sciences Research Council (BBSRC)
EBTC Webinar Series 2013: Wastewater as a resource: A lifecycle assessment
EBTC services and activities in Biotechnology
Session-3
Dr. Geetha Swamilingiah
Biotechnology Sector Specialist
EBTC
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Technology Transfer & Deployment
Demand-Supply maturity matching essential for successful collaborations
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EBTC Consortium Partners
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54 countries, and close to 600 member organisations, across the EU and beyond.

Enterprise Europe Network consortium in India: EBTC, FIEO, and CII/GITA.

The network will help MSMEs from India make the most of the European marketplace, and helps
European businesses make the most of the Indian marketplace.

Working through local business organisations, the network can help organisations to:
- Go international
- Transfer technology
- Access EU finance and EU funding
- Give advice on EU laws and standards
- Intellectual property and patents
- Speak up on EU law
EBTC Enterprise Europe Network - India
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Guiding European Businesses to India
Step 1
Market Insight
Guidance on doing business and research in India
Information on regulatory framework
Information on market access barriers
Intellectual Property Rights (IPR)- Helpdesk
Focused market reports

Step 2
Market Access Roadmap
Screening of projects in India at national
or state level
Identification of potential business partners
Design of market entry strategy
Customised market intelligence








Step 3
Market Strategy Implementation
Proactive incubation services to acclimatize with
minimum risk and costs
Hands-on-support in bidding for projects
Assistance in finalizing pilot projects
Liaising with government and financial institutions
EBTC services: taking European organizations from the point of
considering the Indian market to implementing their projects
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EBTC Biotech Service Portfolio
Research Activities
Network Managers in EU
Aid to develop Proposals and
Information on funding
Schemes
Building Consortium
Technology Transfer
Technology Assessment
Identification of Partners
Risk Factor Mitigation
Successful Transfer
Manufacture
Adaptability
Access the Technology and
Local Expertise
Government Approvals
India Local manufacturer
Contract Research/
Clinical Application
CRAMS and Therapeutic areas
Commercialization Process
Agents/Distributors
Local Chain Supply
Risk Factor Mitigation
J oint Ventures
Partner Selection
Agreements and I PR
EBTC: comprehensive Biotech services provided across the value chain
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EBTC Current Activities in Research & Innovation
IPR Helpdesk
EBTC: comprehensive IPR services provided
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EBTC Biotech Delegation Visit
I nteraction with Biotech Key stake holders
1 & 2. PAN EU delegation(Germany, UK,
Estonia, Czech Republic and Poland)

3. High Level Interaction with Mr. I.S.N
Prasad, Principal Secretary, Department
of Information Technology, Biotechnology
and Science & Technology, Government
of Karnataka and other State Dignitaries
1 2
3
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EBTC Biotech Delegation Visit- Contd.,
Key note speaker and other distinguished guests

1 2
Other activities during the mission
More than 40 Indian companies/ organization for EU Collaboration
Technical Sessions over the subsectors
EBTC Advisory Session-IPR and other regulatory issues
Customized B2Bs with 60+ Indian companies
Customized Site Visits
Mutual Agreement with ABLE
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1. Technology / Project type:
J oint Research Collaboration-
Biomarker discovery using companys patented
technology - functional genomic fingerprinting technology
Indian Organization: Genome Life sciences India Pvt.
Ltd.,
EU Organization: Heidelberg Technology Park,
Germany

EBTCs role: Partnership facilitation
Status: Discussions are in progress


EBTC Biotech Collaboration Facilitation
Case Study 1: Heidelberg Technology Park and
Genome Life Sciences, India
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1.Technology / Project type:

J oint Research Collaboration-for developing diagnostic kit
for Familial Colorectal Cancer Type X (FCTX)
Indian Organization: Genome Life sciences India Pvt. Ltd.,
EU Organization: IGEN, Estonia

EBTCs role: Partnership facilitation
Status: Discussions are in progress




EBTC Biotech Collaboration Facilitation
Case Study 2: IGEN, Estonia and Genome Life
Sciences, India
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EBTC Biotech Collaboration
Partnership Search Facilitation for the following organization
during the mission/ inquiries:
1. France Based BioAgri Industry
2. Hungarian based Food Industry
3. Estonian based Biotech Company for their Product and services
based collaboration
4. Czech Republic based biopharma company
5. A Danish based Bioagri Industry




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Conclusion
EBTC: a platform for EU-Indian collaboration
Indian needs, demands, and partners
continuously being identified
Interested in business opportunities?
Looking for technology collaborations?
Are you planning to develop project?
Looking for business & academic partners?
Interested in research consortium & projects?
Ready to go Indian Biotech Opportunities-
http://www.ebtc.eu/ebtc-project-opportunities-
downloadscenter-biotech.html
Connect with EBTC:
Website: www.ebtc.eu
E-mail: info@ebtc.eu
Follow us:



Questions & Answers
Dr. Geetha Swamilingiah
Biotechnology Sector Specialist
EBTC
Mr. Siddharth Dhodi
Manager, Life sciences Knowledge Banking
YES BANK LTD.
Mr. Amitesh Suman
Senior Manager,
Operations & Business Development
ABLE

EBTC New Delhi (Head Office)
DLTA Complex, South Block, 1st Floor
1, Africa Avenue, New Delhi 110 029, I NDI A
Tel: +91 11 3352 1500
Fax: +91 11 3352 1501
info@ebtc.eu
www.ebtc.eu
New Delhi | Mumbai | Bengaluru | Kolkata | Brussels
The contents of this document are the sole responsibility of the European Business and Technology Centre,
and can under no circumstances be regarded as reflecting the position of the European Union.
Thank You!
Contact us at biotech@ebtc.eu