()

Aedes albopictusAedes aegypti

[1]

2
2
123,000

Group IV(+)ssRNA

(Flaviviridae)

(Flavivirus)

(Dengue virus)

1
2
3
4
5
6
7
8
9
10
10.1
10.2
11
11.1
11.1.1
11.1.2
11.1.3
11.1.4
11.2
11.2.1

11.2.2
11.2.3
11.2.4
12
13
14
15

ICD-10

A90.
(http://www.who.int/classifications/apps/icd/icd10online/?
ga00.htm+a90)

ICD-9

061 (http://icd9.chrisendres.com/index.php?
action=search&srchtext=061)

DiseasesDB 3564 (http://www.diseasesdatabase.com/ddb3564.htm)

MedlinePlus 001374
(http://www.nlm.nih.gov/medlineplus/ency/article/001374.htm)
eMedicine

med/528 (http://www.emedicine.com/med/topic528.htm)

MeSH

C02.782.417.214
(https://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?
mode=&term=Dengue&field=entry#TreeC02.782.417.214)

DengueDengueSwahiliKi-dinga pepo

[2][3]

1779
1779
1780
1780
1780
1873
1897
1910
1916-1931
19173
1928

194319441952
dengue 1 virusdengue 2 virus1956
dengue 3 virusdengue 4 virus
1931Simmons
1978RudnickAedes (Finlaya) niveus complex1984Yuwono

19871990
1983Rosen
1993Chen

1993Chen
[4]
1953310
dengue hemorrhagic fever; DHF(dengue shock syndrome; DSS)12%
44%
201470
20142014929 11867 6631689.89%4
31 [5]

25251980
61151990Halstead1970198025

[6]
15
[7]

815

812

1.
2.
3.
4.

1
2
3
4

FlaviviridaeDEN-1, 2, 3, 4RNA
single positive-strand RNAcapsid; coremembrane; Menvelope; E

50nmRNA11 kilobases
RNAstructural proteins:

PrM

nonstructural; NS:
5*C-PrM-E-NS1-NS2A-NS2B-NS3-NS4A-NS4B-NS5 3

1970
[8]
[9]

1.

39C40C

2.

<20 mmHg

2448

(2)(4)

 (2)(4)

(tourniquet test)

90%96%

(20)

(10)
( 20% )

(Reverse Transcriptase-Polymerase
Chain Reaction; RT-PCR)RNARNA(RNA sequence)
RNA(primer)

[10]
:
1.( ) 2.
(

19884,389
19904
1994
200120025,345(dengue shock
syndromeDSS)240211987
20101100
10/21[1] (http://www.cdc.gov.tw/ct.asp?xItem=31055&ctNode=977&mp=130)

[11]

[11]

[11]

2000 27 113
2001 55 215
2002 52 5336
2003 59 86
2004 91 336
2005 104 202
2006 109 965
2007 179 2000
2008 226 488
2009 204 848

2000 650

[12] [13] [14]

33443 1884 3343

18617

673

139

2001 3306 45904 15695 4304

139327

2372

281

2002 1926 40377 16047 8931

114800

3945

5388

2003 12754 51934 7907 4749

62767

4788

145

2004 4153 79462 7369 15408

38367

9459

427

2005 11985 95279 17454 5856

45893

14209

306

2006 11251 106425 11383 11906

42456

3127

1074

2007 5534 188115 15033 7135

46829

8826

2179

2008 11476

89626

7032

714

2014

5644

10112

1. ^ Kumar & Clark Clinical Medicine 5th Edition, 2002, Sauders, Dengue, 55-57.
2. ^ ; ; ;. . "992
"
3. ^ International Journal of Biomedical Science (http://www.ijbs.org/User/ContentFullText.aspx?VolumeNO=9&StartPage=61). [2013-08-23]. "The first
case of probable dengue fever (DF) was recorded in a Chinese medical encyclopedia from the Jin Dynasty (265420 AD) which referred to as
water poison associated with flying insects."
4. ^ Chen W.J., Wei H.L., Hsu E.L. & Chen E.R. 1993. Vector competence of Aedes albopictus and Ae. aegypti (Diptera: Culicidae) to dengue 1 virus
on Taiwan: development of the virus in orally and parenterally infected mosquitoes. Journal of Medical Entomology. 30(3): 524-530.
5. ^ (http://www.infzm.com/content/104566). . 2014-09-29.
6. ^ Rico-Hesse R. Molecular evolution and distribution of dengue viruses type 1 and 2 in nature. Virology 1990;174:1-15.
7. ^ Carey DE. Chikungunya and dengue: a case of mistaken identity? J Hist Med 1971; 26: 243-62.
8. ^ (http://www.apdnews.com/news/31793.html)2013814
9. ^ First Vaccine for Dengue Fever Shows Promise in 2nd Big Trial (http://www.nytimes.com/2014/09/04/business/experimental-vaccine-shows-promiseagainst-dengue-fever.html?_r=0)New York Times SEPT. 3, 2014
10. ^ Alexis Madrigal. Engineered Mosquitoes Could Wipe Out Dengue Fever (http://www.wired.com/science/planetearth/news/2008/01/gm_insects). wired.
2008-01-23 [2008-01-28].
11. ^ 11.0 11.1 . (http://www.cdc.gov.tw/public/data/971616111271.pdf). : . 2009.
12. ^ Department of Disease Control, Ministry of Public Health. ANNUAL EPIDEMIOLOGICAL SURVEILLANCE REPORT
(http://203.157.15.4/Annual/Total_Annual.html).
13. ^ Ministry of Health, Singapore. MOH weekly publication of statistics on local infectious disease situation
(http://www.moh.gov.sg/mohcorp/statisticsweeklybulletins.aspx).
14. ^ . (http://nidss.cdc.gov.tw/default.aspx).

-Flaviviridae() (http://smallcollation.blogspot.com/2013/02/flaviviridae.html)
(http://news.sina.com.cn/c/h/2006-09-01/114210894799.shtml)
(http://news.xinhuanet.com/health/2005-01/06/content_2422966.htm)
(http://www.who.int/topics/dengue/zh/index.html)
(http://shengwei95.wordpress.com/2010/02/05//)

eMedicine() (http://www.emedicine.com/emerg/topic124.htm) Dengue Fever

(http://shengwei95.wordpress.com/2010/02/08/%E7%99%BB%E9%9D%A9%E7%83%AD%EF%BC%88%E9%AA%A8%E7%97%9B%E7%83%AD%E7%97%87%EF%BC%89%E9%98%B2%E6%B2%BB%E5%B8%B8%E8%AF%86/)
() (http://www.cdc.gov)
http://zh.wikipedia.org/w/index.php?title=&oldid=33070318

20141025 () 02:14
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