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Introduction to
Molecular
Medicine
MMED 1103
MB,BS Undergraduate Medical Curriculum
Year 1, Semester 1
Introduction to
Molecular
Medicine
MMED 1103
Course Coordinator
Professor Norma McFarlane-Anderson
Section of Biochemistry
Cell Biology
Cell Biology
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Cell Biology
Cell Biology
Useful Revision
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Core Content
The following general areas are covered
1. DNA, RNA structure, chromosomes, genes,
genetic code, gene expression, mutations,
genome diversity, laboratory manipulation of
nucleic acids
2. How genes are inherited, population genetics
3. Molecular techniques, emphasizing those used
in diagnosis and treatment
4. Molecular medicine in practice recombinant
proteins, gene therapy, pharmacogenomics, the
Human Genome Project (HGP).
5. Ethical considerations and implications in the
application of molecular biology to medicine.
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Cell Biology
Cell Biology
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Cell Biology
Glossary of terms
Allele - One of the different forms of a gene that can
exist at a single locus on a chromosome
Autosomes - All the chromosomes except the sex
chromosomes; found in somatic cells
cDNA - A singlestranded DNA complementary to an
RNA from which it was synthesized using reverse
transcriptase
Clone - A large number of cells or molecules derived
from a single ancestral cell or molecule
Cell Biology
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Cell Biology
Teaching/Learning Methods
These will include lectures, tutorials,
practical laboratory sessions, visits to
laboratories on and off-site and computer
based sessions. In addition to the three
listed, there are also many informative
websites which can be accessed.
Not all of the objectives will necessarily be
covered in the lectures and students are
encouraged to use the learning objectives
provide in this guide and the clinical
problems they will see to guide their selfstudy.
Regular small group discussion is an
excellent way of reviewing and reinforcing
your knowledge and students are
encouraged to use this approach to learning
not only in formal activities but throughout
their programme of study.
Cell Biology
Useful Resources
Textbooks
Assessment
On completion of this course, students will
be assessed by a written (Multiple Choice
Question) examination paper. However,
attendance at the practical sessions is
mandatory and a student must obtain a
satisfactory grade on the written report.
Failure to do so may result in the student
being debarred from writing the final
examination.
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Useful Websites
http://www.ncbi.nlm.nih.gov/About/primer/gene
tics.html
http://en.wikipedia.org/wiki/Genetic_fingerprinti
ng
http://www.genome.gov/10001772
Prepared handouts
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