Molecular Characterization of Spinal Muscular Atrophy

Acknowledgement
“With the blessing of Lord Krishna”

Research is a continuous process undertaken by an individual or a team of persons

probing into the never ending, newer avenues of science. Many people known and
unknown have contributed to the strengths of the dissertation. It is the matter of
pride and elation for me to acknowledge the contribution of those individuals who
have been inspirational, supportive and helpful throughout my work, and endowed
me most precious knowledge to see success in my endeavor. My work bears the share
of all those people and I am heartily grateful to all of them.

In the first place I would like to record my gratitude to Dr. Navin Sheth, Head and
Professor, Department of Pharmaceutical Sciences, Saurashtra University, Rajkot,
for his consent, motivation and suggestions. Above all the most needed, he provided
me unflinching encouragement and support in various ways. His truly scientific
intuition has made him as a constant oasis of ideas and passions in science, which
exceptionally inspire and enrich my growth as a student and researcher. I am
indebted to him more than he knows.

With profound pleasure, I express my deepest gratitude to my esteemed guide, Dr.

JAYESH SHETH, Director, Foundation for Research In Genetics & Endocrinology,
Institute of Human Genetics, Satellite, Ahmedabad, for allowing me to carry out
M.Pharma dissertation work within a well-established organization along with his
7timely suggestions, unflinching encouragement and critical remarks for the entire
span of my work. His involvement and his originality has triggered and nourished my
intellectual maturity that I will benefit from, for a long time to come. His perpetual
energy and enthusiasm in research had motivated all his advices including me. In

Dept. of pharmaceutical sciences,Saurashtra University,Rajkot.

Molecular Characterization of Spinal Muscular Atrophy

addition, he was always accessible and willing to help his students with their
research. He has been a pillar of strength and support without whom would not have
been brought to completion.

I am honorably thankful to Dr. Frenny Sheth, Asst. Director, Foundation for

Research in Genetics & Endocrinology, Institute of Human Genetics, Satellite,
Ahmedabad, for her valuable guidance toward the success of this work.

I express my special thanks to Mr. Pratik Upadhyay, Asst. Professor, Department

of pharmaceutical Sciences, Saurashtra University, Rajkot for his valuable guidance,
constant encouragement, moral support and dynamic cooperation throughout my
dissertation work during entire period, without his help I cannot complete this work.

I owe a special word of thanks to Ms. Anamika Gupta, Research Asst., Foundation
for Research in Genetics & Endocrinology, Institute of Human Genetics, Satellite,
Ahmedabad, for her valuable guidance toward the success of this work.

I express my special thanks to Mrs. Manisha Desai, Ms. Preeti Damania, Mr. Sihir
Mehta, Ms. Jhumur Pani, Mr. Mehul and all other members of Institute of Human
Genetics, who directly and indirectly helped me for the success of this work.

I am obliged to Mr.Nilesh Patel, Mr. Mahesh Dabhi, Mr. Ashvin Dudhrejiya,

Mr. Sachin Parmar, Assistant Professors, Department of pharmaceutical Sciences,
Saurashtra University, Rajkot for their valuable guidance during entire period.

How can I forget to thank Ms. Jalpa, Mr. Satyam Jadeja, Mrs. Nainamadam, Mr.
Hareshbhai, Mrs. Shabanamben, Mr. Vipulbhai, and Mr. Dhavalbhai for helping me
during my project period.

Dept. of pharmaceutical sciences,Saurashtra University,Rajkot.

Molecular Characterization of Spinal Muscular Atrophy

I am especially thankful to my classmates. They inspired me, encouraged me in a

variety of ways, their love ,care, patience, guidance and support have always been
strength for me, without their helpful co-operation and suggestions from time that I
needed it was difficult for me to complete my work.

Last but not least, I express my heartiest regards to my father Mr. Lalabhai B. Patel
and my Mother Mrs. Laxmiben L. Patel for their energetic, moral and economical
support that boosted my spirits. It is because of them I have reached the place where
I am today. I am very much thankful to my brother Manoj, my bhabhi Gaytriben and
my sisters Chetana and Varsha, my fiancée Dr. Neha patel for their immense love,
care, emotional support and confidence that they infused in me, without whom this
momentous work could not have been completed.

Last, definitely not the least I pay reverence to the almighty, omniscient,
omnipresent, omnipotent, supreme soul who has perpetually patronize me with the
contentiousness and love.

Yours sincerely,
Jitendra L. Patel.

Dept. of pharmaceutical sciences,Saurashtra University,Rajkot.