Diseases of the G.I.

Tract
Anatomy:
Oral Cavity to - Anal Canal
Reference:
The Guide: 78 - 99

Robbins book: 763- 829

Histology
Mucosa:

Submucosa:

Musculosa:

Adventitia:
esophagus

Oral Cavity
Mixed Parotid Tumor
(Pleomorphic):

.
Peutz-Jeghers syndrome:

A. Congenital
1. Tracheo-esophageal fistula
2. Diverticulae:
True:

False:

Esophagus

Esophageal Diverticulae
1. Pulsion diverticula:
2. Zenkers diverticula:

3. Traction diverticula:

Esophageal
Diverticula

Esophageal Achalasia
Definition:

3 Features:
1.
2.
3.

Inflammation of the esophagus

1. Esophagitis:

Pathology:

Esophagitis
Barretts esophagus

Tumors of the esophagus

1. Benign: Leiomyoma

Tumors of the esophagus

2. Malignant:
a. Squamous cell
carcinoma:

Factors:

a. Squamous cell carcinoma of the esophagus

Clinical:

b. adenocarcinoma of the
esophagus

Congenital pyloric stenosis of the stomach

Def:
Pathology:
Clinical findings:

Hiatal hernias
a. Sliding H. H.:
b. Paraesophageal H.
Complications:

 Para-esophageal
hiatal hernia

Gastritis

Acute Gastritis:
Chronic atrophic gastritis:
Chronic gastritis:

H. pylori

gastritis

Peptic ulcer

Peptic Ulcer
Any age

Peptic Ulcer
Path. underlined ulcer,
Clinical:
Complications:
Diagnosis:

Tumors of the Stomach

a. Leiomyoma:

Tumors of the Stomach

b. Gastric polyps:
hyperplastic
adenomatous
polyps

Gastric adenocarcinoma
Gross: MC in
lesser curvature
5 forms:
1.Fungating
2.Ulcerative
3.Flat mucosa
4.Polypoid

Indurated
ulcer

Gastric adenocarcinoma
5.Diffuse infiltrative:

Spread:
(Kruckenbergs) and
neck (Sentinal or
Virchows nodes)

Linitis plastica

Omphalo-mesenteric
duct

Small intestine
Congenital:
Meckels
diverticulum:

Rule of 2s

Meckels diverticulum:
Complications:
- - --

Inflammation of the S. Intestine

Malabsorption
syndrome:
Definition
Etiology:
1.Giardiasis:

Normal

2.Celiac Sprue

3.Tropical Sprue: -4.Whipples disease: ------

Mechanical disorder (S. intestine)

Intussusception

Mechanical disorder
Volvulus:

Tumors of the S. Intestine

Leiomyoma: --Carcinoid tumor: ----

Large intestine
Congenital: Hirsch-Sprungs disease:

Pseudomembranous Colitis:

Clostridium difficile,

Inflammation of Large intestine

Normal large intestine

Crohns disease:
definition, incidence etiology, pathology, clinical findings,
complications

 Granuloma
tramsmural
adult
equal sex
Jews
MC in
ileum &
colon

Crohns

Ulcerative Colitis
Def.,
etiology,

-- -- - ---

Ulcerative Colitis

Tumors of L. intestine
Tubular adenoma

Villous adenoma

----

Familial polyposis

--100% pre-cancer

Colorectal cancer
Adenocarcinoma

-----

Dukes classification of
colo-rectal cancer

Appendicitis:
Def
Etiology:
Pathology:
Clinical findings:
Complication: