Professional Documents
Culture Documents
Pharmaceutical Relevance
Type of organism
Contamination or
spoilage of raw
materials
and medicines
Pathogens
Resistance to
antibiotics and
biocides
Viruses
Prions
Gram-negative
Gram-positive
Resistance to
sterilizing
agents
and processes
Used in the
manufacture of
therapeutic
agents
Implications
Because of their lack of intrinsic metabolism viruses
are not susceptible to antibiotics and the number of
effective synthetic antiviral drugs is limited so viral
infections are among the most serious and difficult
to cure. They have no synthetic capabilities that can
be exploited in medicine manufacture.
Prions are hard to destroy by heat, radiation or toxic
chemicals, they have their extreme resistance to
lethal agents so for this reason, they can easily
withstand sterilizing conditions so they cause
product spoilage, and they have no synthetic
capabilities that can be exploited in medicine
manufacture.
Bacteria
+
+ (spores)
Mycobacteria
Streptomycetes
Chlamydia
Rickettsia
Mycoplasma
Fungi
Yeasts
Moulds
Protozoa