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Exercise 2: Skeletal Muscle Physiology: Activity 4: Tetanus in Isolated Skeletal Muscle Lab Report
Pre-lab Quiz Results
You scored 33% by answering 1 out of 3 questions correctly.
1. Stimulus frequency refers to
Your answer : c. the rate of force development in stimulated twitches.
Correct answer: b. the rate that stimulating voltage pulses are applied to an isolated whole skeletal muscle.
2. Which of the following distinguishes a state of unfused tetanus from a state of complete (fused) tetanus?
You correctly answered: d. Muscle tension increases and decreases during a state of unfused tetanus.
3. When the stimulus frequency reaches a value beyond which no further increases in force are generated by the muscle,
the muscle has reached its
Your answer : c. unfused tetanic tension.
Correct answer: a. maximal tetanic tension.
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Experiment Results
Predict Question:
Predict Question: As the stimulus frequency increases further, what will happen to the muscle tension and twitch
appearance with each successive stimulus? Will there be a limit to this response?
Your answer : b. As the stimulus frequency increases, the muscle tension generated by each successive stimulus will
increase. There will be a limit to this increase.
Stop & Think Questions:
What begins to happen at around 80 msec?
You did not answer this question.
Correct answer: c. unfused tetanus develops
How does the trace at 130 stimuli/sec compare with the trace at 50 stimuli/sec?
You did not answer this question.
Correct answer: b. Fused tetanus develops at this greater stimulus frequency.
How do the traces with 146150 stimuli per second compare with the trace at 130 stimuli per second?
You correctly answered: d. Maximal tetanic tension develops with these very high stimulation frequencies.
Experiment Data:
Voltage
8.5
8.5
8.5
8.5
8.5
8.5
8.5
8.5
Length
75
75
75
75
75
75
75
75
Stimuli/sec
50
130
140
142
144
146
148
150
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Active Force
5.12
5.88
5.91
5.92
5.94
5.95
5.95
5.95
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Passive Force
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
Total Force
5.12
5.88
5.91
5.92
5.94
5.95
5.95
5.95
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