Professional Documents
Culture Documents
BIOLOGY
INVESTIGATORY PROJECT
A.JAYVARDAN
KV NO.2, Jalahalli
East,Bangalore.
What Is Cellulites?
Cellulitis is a bacterial infection involving the skin. It specifically
affects the dermis and subcutaneous fat. Signs and symptoms include an area
of redness which increases in size over a couple of days. The borders of the
area of redness are generally not sharp and the skin may be swollen. While
the redness often turns white when pressure is applied this is not always the
case. The area of infection is usually painful. Lymphatic vessels may
occasionally be involved and the person may have a fever and feel tired. The
legs and face are the most common site involved, though cellulitis can occur on
any part of the body. The leg is typically affected following a break in the
skin. Other risk factors include obesity, leg swelling, and old age. For face
infections a break in the skin beforehand is not usually
the case. The bacteria most commonly involved are
streptococci and Staphylococcus aureus. In contrast
to cellulitis, erysipelas is a bacterial infection involving
the more superficial layers of the skin, presents with an
area of redness with well-defined edges, and more
often is associated with fever. More serious infections
such as an underlying bone infection or necrotizing
fasciitis should be ruled out. Diagnosis is usually
based on the presenting signs and symptoms with cell
culture rarely being possible. Treatment with antibiotics
taken by mouth such as cephalexin, amoxicillin or cloxacillin is often used. In
those who are seriously allergic to penicillin, erythromycin or clindamycin may
be used. When methicillin-resistant Staphylococcus aureus (MRSA) is a concern
doxycycline
or
Trimethoprim/sulfamethoxazole
may,
in
addition,
be
recommended. Concern is related to the presence of pus or previous MRSA
infections. Steroids may speed recovery in those on antibiotics. Raising the
infected area may be useful as may pain killers. Around 95% of people are
better after seven to ten days of treatment. Potential complications include
abscess formation. Skin infections affect about 2 out of every 1000 people
per year. Cellulitis in 2010 resulted in about 27,000 deaths worldwide that
year. In the United Kingdom cellulitis was the reason for 1.6% of admissions
to the hospital.
Symptoms
Possible signs and symptoms of cellulitis include:
Redness
Swelling
Tenderness
Pain
Warmth
Fever
The changes in your skin may be accompanied by a fever. Over time, the
area of redness tends to expand. Small red spots may appear on top of
the reddened skin, and less commonly, small blisters may form and burst.
Causes
Cellulitis occurs when one or more types of bacteria enter through a
crack or break in your skin. The two most common types of bacteria that
are causes of cellulitis are streptococcus and staphylococcus. The
incidence of a more serious staphylococcus infection called methicillinresistant Staphylococcus aureus (MRSA) is increasing.
STREPTOCOCCUS
STAPHYLOCOCCUS
Although cellulitis can occur anywhere on your body, the most common
location is the lower leg. Bacteria is most likely to enter disrupted areas
of skin, such as where you've had recent surgery, cuts, puncture wounds,
an ulcer, athlete's foot or dermatitis.
Certain types of insect or spider bites also can transmit the bacteria
that start the infection. Areas of dry, flaky skin also can be an entry
point for bacteria, as can swollen skin.
.
Predisposing conditions for cellulitis include insect or spider bite,
blistering, animal bite, tattoos, pruritic (itchy) skin rash, recent surgery,
athlete's foot, dry skin, eczema, injecting drugs (especially subcutaneous
or intramuscular injection or where an attempted intravenous injection
"misses" or blows the vein), pregnancy, diabetes and obesity, which can
affect circulation, as well as burns and boils, though there is debate as
to whether minor foot lesions contribute.