Job Description

Bioinformatics Scientist NGS

At Genome Life Sciences (GLS) we develop innovative algorithms, tools and databases for analysis of
biomedical and genomics data, biomarker discovery, and translational/clinical research for healthcare,
veterinary, agriculture, and food industries. GLS is a DSIR (Department of Scientific & Industrial
Research, India) recognized R&D organization providing contract research, sequencing as a service and
turn-key solutions in translational, clinical, agricultural and veterinary genomics research.
We are looking for a Scientist in NGS Data Analysis to join our rapidly expanding clinical genomics
division in the computational biology and genome analysis group. As Bioinformatics Scientist you will be
responsible for the analysis and interpretation of next-generation sequencing (NGS) data.

ABOUT THE ROLE

This work will be done as part of a team of Scientists, Clinicians, Programmers and Analysts passionate
about solving complex scientific problems in biology and genetics ranging from cancer genomics to plant
germplasm selection. The job requires creating and using software systems to analyze biological data.
Some of the common scenarios include variant prioritization from cancer samples, building custom
databases for clinical conditions or of pharmaceutical importance. Publication of genuinely developed
methods may be encouraged.
The Scientist will play a key role in delivering NGS and microarray data analysis projects, supporting
product development, managing NGS projects for clients and offering guidance to Programmers and
Analysts.

RESPONSIBILITIES

Develop methods, protocols and algorithms for analysis NGS data for clients from pharmaceutical,
biotech and academic institutions worldwide

Analyze sequencing data, perform appropriate QC measures and interpret the results as per clients
requirements

Define and implement quality control procedures at both technological and biological levels for
high volumes of NGS data. Assist, collaborate, consult with internal/external researchers on
analyses of NGS data

Contribute for proposal development and scientific writing in Grants and Solicitations.

Genome Life Sciences Pvt. Ltd.| Confidential

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Job Description
POSITION REQUIREMENTS

Ph.D. in Bioinformatics, Computational biology, Genetics or Statistics

Demonstrated experience in NGS data analysis of sequencing data (Whole Genome, Exome,
RNA-Seq, ChIP-Seq, Methyl-Seq, miRNA-Seq) as evidenced from PhD and work experience

5+ years experience programming in Perl, R, Python, Unix shell scripting a must. C++, JAVA or
other OOP advantageous

Proficiency in utilizing data from public resources such as TCGA, COSMIC, NCBI, ENSEMBL,
etc. for development purposes.

Demonstrated experience or training in statistics or machine learning preferred

Experience working in a local distributed computing cluster and cloud environments essential

A high tolerance for change and a sense of urgency since GLS is in log-phase

Team oriented with excellent written and verbal communication skills

CANDIDATE PROFILE
The ideal candidate will be a skilled professional with broad experience in bioinformatics especially in
functional and comparative genomics, Next Generation Sequence (NGS) analysis, high throughput
genome annotation and analysis pipeline development. The ability to work with and integrate other
omics data-types with core sequence information is highly desired. You should also possess strong
interpersonal, organizational, and communication (verbal and written) skills.

Someone with MBBS/B Tech(Premier institutes) AND PhD( Bioinformatics/computational

Biology) plus 3-4 years Post Doc/industry experience will be preferable.

(Five years of industrial/research lab experience plus a Masters degree will be considered to be equivalent
to a Ph.D.)

Genome Life Sciences Pvt. Ltd.| Confidential

Ver 1.1