USP Dissolution Apparatuses

By Dr. Luke Lee

USP Apparatus 1,2,5,6,

Physical Calibration tool set

Wobble gauge & Stand
Centering Shaft

Speed tachometer

Thermometer

Timer

USP Apparatus 3,7,

LOGAN USP DISSO III Classic

USP Dissolution Method 7

UDT-804-12+2 Universal Dissolution Tester

UDT-804-2L Universal Dissolution Tester

(2L Dissolution tester)

UDT-804-2L Universal Dissolution Tester

(2L Dissolution tester)

UDT-804-4L Universal Dissolution Tester

(2L Dissolution tester)

SYSTEM 800S

with SHIMADZU UV 1600 /1650/1700

Automated Dissolution UV System

SYSTEM U800S

with SHIMADZU UV 1600/1650/1700

Automated Dissolution UV System

Method
Product
Sample

SYSTEM 850K For HPLC off line analysis

Automated Dissolution Syringe Pump Sampling System

SYSTEM 850KS-12
Automated Dissolution Syringe Pump Sampling System

SYSTEM 850K-2S For HPLC off line analysis

Automated Dissolution Syringe Pump Sampling System

One system controller to control 2 dissolution sampling systems

LOGAN/pION
Fiber Optic Dissolution System

Logan UDT-804 Dissolution Tester

pION Fiber Optic System

LOGAN/pION
Fiber Optic Dissolution System
Moving Plate

Fiber Optic Probes

LOGAN Bubble Kicker manifold design

(patented)

LOGAN/pION
Fiber Optic Dissolution System

MDS 600
Media Delivery System
* Mobile unit brings media to
dissolution tester
* Six Vessels filled to the same
volume simultaneously
* Volume delivered to better than
+/-1%
* Deaerated by filtration,
circulation, vacuum and heat.

MDS 600
Media Delivery System
MDS-600 Delivery
Manifold

UDT-804
Dissolution Tester

MDS 600T
Media Delivery System
* Table top unit fills
media into 6
dissolution vessels
* Six Vessels filled to
the same volume
simultaneously
* Volume delivered to
better than +/-1%
* Deaerated by
filtration, circulation,
vacuum and heat.

MDS 600T
Media Delivery System
Vessel tray for carry 6
dissolution vessels to
dissolution tester

MDS 600T
Media Delivery System
Media
reservoir

Delivery
manifold

Heater /
Degassing
system

MDS 600T
Media Delivery System

Media reservoir &

Temperature controlling
system for degassing
Total of 4 types media
reservoir / degassing
system can be link up
with the MDS-600T

AVC-100 HT
Automated Vessel Cleaner
For Validation
Mobile unit brings
cleaner to bath
* High pressure turbo
wash and vacuum
* Media neutralization in
waste tank
Automatic waste
discharge

AVC-100
Automated Vessel Cleaner
Wash Head

UDT-804
Dissolution Tester

AVC-100 HTB Automated Vessel Cleaner

Wash Head Design

Wash head with

built-in brush

LOGAN SYSTEM 7000-24

Automated USP 7
Hip Stem Test System

LOGAN SYSTEM 7000-24

Automated Hip Stem Test System

LOGAN SYSTEM 7000-24

Automated Hip Stem Test System

SYSTEM CONTROLLER
LCD Display
Touch Screen

LOGAN SYSTEM 7000-24

Automated Hip Stem Test System

LOGAN Fully Automated USP 7

System

LOGAN SYSTEM 1000

Fully Automated Dissolution System
Schematic
System 1000 total control
software package
Cleaning

Logan UDT-804AB Air bath

with vessel filling nozzles & wash /
rinse station & sampling manifolds
USP I : 8 Tests USP II : 12 Tests
A. Vessel face up design
B. Vessel face down design

AVC-1000

Waste

Filling

MDS-600

Media A
Tank

Media B
Tank

Media C
Tank

Transfer
pumps for
sampling

Sample
collector

Media Supply Tank

Rinse Water
Tank

Sampling

Media D
Tank

Media E
Tank

Analysis
Fiber optic
probes
On line UV

HPLC
injection

LOGAN SYSTEM 1000

Fully Automated Dissolution System
UDT-804AB (Air Bath)
Heater in the shaft

Air chamber for temperature

isolation

Temp read-out for

each vessel

Temperature sensor under the vessel

LOGAN SYSTEM 1000

Fully Automated Dissolution System
Media Filling

Dissolution Media Filling by MDS-600

Media Delivery Module
* Automatically fills pre-heated degassed media
into 6 test vessels
* 6 Vessels filled to the same volume
simultaneously
* Volume delivered to better than +/-1%

NOTE: 5 types of media can be select by

program, selected media transferred into
MDS-600 reservoir for pre-heat

LOGAN SYSTEM 1000

Fully Automated Dissolution System
USP I Basket Test
For USP I Basket Test:
Preload baskets in the
carousal
Max: 8 tablets
The basket carousal is
stationed between each
drive head and vessel. The
shaft engages basket before
it gets into the vessel

LOGAN SYSTEM 1000

Fully Automated Dissolution System
USP II Paddles Test
For USP II Paddle Test:
Preload tablets in the
carousal
Max: 12 tablets
The tablet carousal is
mounted on top of the driver
head

LOGAN E Trans SYSTEM

The drug delivery system thru eyes into the brain

LOGAN E Trans SYSTEM

The drug delivery system thru eyes into the brain

Apply drugs from eyes

LOGAN INSTRUMENTS CORP.

19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Prepared by Dr. Luke Lee

THANK YOU!