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Although the ability to measure pain in children has improved dramatically in recent years,
assessment of pain in children continues to be complex and challenging.
Behavioral assessment is useful for measuring pain in infants and preverbal children who do
not have the language skills to communicate that they are in pain, or when mental clouding
and confusion limit a childs ability to communicate. Behavioral pain assessment may
provide a more complete picture of the total pain experience when administered in
conjunction with a subjective self-report measure.
Physiologic measures are not able to distinguish between physical responses to pain and
other forms of stress to the body. Physiologic parameters such as heart rate, respiratory rate,
blood pressure, palmar sweating, cortisone levels, transcutaneous oxygen, vagal tone, and
endorphin concentrations reflect a generalized and complex response to stress. They are not
localized response to pain, but they provide useful information about general distress levels
of children experiencing pain.
The number of pain measures that are available for use in infants and young children has
increased dramatically and adds a layer of complexity to the assessment of pain in children.
Important components of assessment include the onset of pain; pain duration or pattern;
effectiveness of the current treatment; factors that aggravate or relieve the pain; other
symptoms and complications concurrently felt; and interference with the childs mood,
function, and interactions with family.
Chronic pain is defined as pain that persists for 3 months or more or beyond the expected
period of healing. Complex regional pain syndrome and chronic daily headache are the most
common types of chronic pain conditions in children. Recurrent pain is pain that is episodic
and recurs. The time frame within which episodes of pain recur is at least 3 months.
Recurrent pain syndromes in children include migraine headache, episodic sickle cell pain,
recurrent abdominal pain, and recurrent limb pain.
Pain is often associated with fear, anxiety, and stress. A number of nonpharmacologic
techniques, such as distraction, relaxation, guided imagery, and cutaneous stimulation, can
help with pain control.
The administration of sucrose with and without nonnutritive sucking has been demonstrated
to have calming and pain-relieving effects for invasive procedures in neonates.
One of the most significant improvements in the ability to provide atraumatic care to children
is the use of anesthetic creams such as LMX (lidocaine) or EMLA (a eutectic mix of local
anesthetics).
Non-opioids, including acetaminophen (Tylenol, Paracetamol) and nonsteroidal antiinflammatory drugs, are suitable for mild to moderate pain; opioids are needed for moderate
to severe pain. A combination of the two analgesics acts on the pain system on two levels:
non-opioids primarily act at the peripheral nervous system, and opioids primarily act at the
All Elsevier items and derived items 2013, 2009, Mosby, Inc., an imprint of Elsevier Inc.
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central nervous system. This approach provides increased analgesia without increased side
effects.
Several drugs, known as co-analgesics or adjuvant analgesics, may be used alone or with
opioids to control pain symptoms and opioid side effects. Drugs frequently used to relieve
anxiety, cause sedation, and provide amnesia are diazepam (Valium) and midazolam
(Versed); however, these drugs are not analgesics and should be used to enhance the effects
of analgesics, not as a substitute for analgesics.
Other adjuvants include tricyclic antidepressants (e.g., amitriptyline, imipramine) and
antiepileptics (e.g., gabapentin, carbamazepine, clonazepam) for neuropathic pain, stool
softeners and laxatives for constipation, antiemetics for nausea and vomiting,
diphenhydramine for itching, steroids for inflammation and bone pain, and
dextroamphetamine and caffeine for possible increased analgesia and decreased sedation.
A significant advance in the administration of intravenous, epidural, or subcutaneous
analgesics is the use of patient-controlled analgesia. As the name implies, the patient
controls the amount and frequency of the analgesic, which is typically delivered through a
special infusion device.
Although respiratory depression is the most feared side effect of opioids, constipation is a
common, and sometimes serious, side effect of opioids, which decrease peristalsis and
increase anal sphincter tone.
Several harmful effects occur with unrelieved pain, particularly when pain is prolonged.
Poorly controlled acute pain can predispose patients to chronic pain syndromes.
Surgery and traumatic injuries, such as fractures, dislocations, strains, sprains, lacerations, or
burns, generate a catabolic state as a result of increased secretion of catabolic hormones.
This leads to alterations in blood flow, coagulation, fibrinolysis, substrate metabolism, and
water and electrolyte balance, and increases the demands on the cardiovascular and
respiratory systems.
Because burn pain has multiple components, involves repeated manipulations over the
injured sites, and has changing pattern over time, it is difficult and challenging to control.
Burn pain includes a constant background pain that is felt at the wound sites and surrounding
areas. Burn pain is exacerbated (breakthrough pain) by movements such as changing
position, turning in bed, walking, or even breathing. Areas of normal skin that have been
harvested for skin grafts (donor sites) also are painful.
Recurrent abdominal pain (RAP), or functional abdominal pain, is defined as pain that
occurs at least once per month for 3 consecutive months, accompanied by pain-free periods,
and is severe enough that it interferes with a childs normal activities. Management of RAP is
highly individualized to reflect the causes of the pain and the psychosocial needs of the child
and family.
The acute painful episode in sickle cell disease is the only pain syndrome in which opioids
are considered the major therapy and are started in early childhood and continued throughout
adult life. A source of frustration for patients and clinicians is that most current analgesic
regimens are inadequate in controlling some of the most severe painful episodes. A
All Elsevier items and derived items 2013, 2009, Mosby, Inc., an imprint of Elsevier Inc.
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All Elsevier items and derived items 2013, 2009, Mosby, Inc., an imprint of Elsevier Inc.