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I Olfactory Nerve:
o Has only sensory function which is for sense of smell
o Consists of olfactory epithelium, bulbs and tracts
o Olfactory epithelium Damage to this nerve is manifested by anosmia
II Optic Nerve:
o Sensory function where it conveys visual information from the retina till it
reaches the visual centers of the brain for interpretation
o Damage to this nerve leads to blindness
III Oculomotor:
o Somatic motor (general somatic effect) supplies four of the six extraocular
muscles of the eye and the levator palpebrae superioris muscle of the upper
eyelid
o Visceral motor (general visceral effect) provides parasympathetic innervation
of the constrictor pupillae and ciliary muscles involved in the pupillary light
and accommodation reflexes
o Damage to the oculomotor can lead to lazy eye, dilated pupil and ptosis
IV Trochlear:
o Somatic motor (general somatic efferent) innervates the superior oblique
muscle of the contralateral orbit
o Trochlear nerve palsy/Superior oblique dysfunction Damage produces
vertical diplopia and hypertropia. Most commonly injured cranial nerve in
head trauma
V Trigeminal:
o 5th cranial nerve, also the largest and most complicated. Different clinical
implications as local anaesthesia, traumatic injuries and viral infections could
affect this nerve.
o Natures of Fibres and Innervations:
Components:
Afferent general Somatic:
o Function :
General sensibility
o Peripheral Distribution:
Sensory branches of the ophthalmic, maxillary
and mandibular nerves to skin, mucous
membranes of the face and head
Efferent Special Visceral:
o Function:
Motor (masticatory function)
o Peripheral Distribution:
Branches to temporalis, masseter, pterygoids,
mylohyoid, tensor timpani and tensor palati
Afferent Proprioceptive:
o Function:
Muscular sensibility
o Peripheral Distribution:
Sensory endings in muscles of mastication
IV Abducens:
o Somatic motor Innervates lateral rectus muscle of ipsilateral orbit
o Damage to the abducens causes issue in left to right movement of the eye
VII Facial:
o Motor control of most of the muscles of facial expression and posterior belly
of the digastric, the stylohyoid and stapedius of middle ear
o Also receives taste from anterior 2/3 of the tongue via chorda tympani,
VIII Vestibulocochlear:
o Vestibulocochlear nerve (also called auditory nerve, acoustic nerve or 8th
cranial nerve) consists of two anatomically and functionally distinct parts
which serve equilibrium and hearing
Cochlear nerve is distributed to hearing organ
Vestibular nerve is distributed to organ of equilibrium
o Damage to VIII leads to vertigo and deafness
o Intracranial Branches:
Greater petrosal nerve which provides parasympathetic innervation to
nasal gland, lacrimal gland, palatine gland and pharyngeal gland as
well as the cranial sinuses and nasal cavity
Nerve to stapedius provides motor innervation for stapedius in middle
ear
Chorda tympani innervates submandibular gland, sublingual gland and
taste fibres for the anterior 2/3 of the tongue
o Extracranial Branches:
Posterior auricular controls some movements of scalp muscles around
ear
Branch to posterior belly of the digastric as well as some of the
stylohyoid
Five major facial branches (in parotid gland):
Temporal branch of facial nerve
Zygomatic branch of facial nerve
Buccal branch of facial nerve
Marginal mandibular branch of facial nerve
Cervical branch of facial nerve
IX Glossopharyngeal:
o Branchial motor (special visceral efferent) Supplies stylopharyngeus muscle
o Visceral motor (general visceral efferent) Parasympathetic innervation of the
parotid salivary gland, smooth muscle and glands of the pharynx, larynx and
viscera of the thorax and abdomen
o General visceral afferent Caries visceral sensory information from the
carotid sinus and body
o General somatic afferent Provides general sensory information from skin of
external ear, internal surface of the tympanic membrane, upper pharynx and
posterior third of the tongue
o Special sensory (special afferent) Provides taste sensation from posterior 1/3
of the tongue
X Vagus Nerve:
o Mixed sensory and motor nerve which wanders into thorax and abdomen and
provides parasympathetic innervation of organs
o Damage to vagus results in dysphagia, hoarseness of voice, loss of cough
reflex (pharynx/larynx), loss of taste sensation in palate (epiglottis)
XI Accessory Nerve:
o Has cranial root and spinal root both consisting of branchial motor fibres:
Branchial motor cranial root (special visceral efferent) Innervates
muscles of larynx and pharynx
Branchial motor spinal root (special visceral efferent) Innervates
trapezius and sternocleidomastoid muscles
XII Hypoglossal Nerve:
o Has only somatic motor (general somatic efferent) component
o Somatic motor innervates all intrinsic and most of extrinsic tongue muscles
o CN XII supplies three of the four extrinsic muscles of the tongue including
genioglossus, styloglossus and hyoglossus
o Palatoglossus is supplied by CN X (Vagus)
o Runs inferior to the tongue and innervates tongue muscles
o Damage can lead to paralysis of the tongue
Arterial Systems:
o Carotid Artery
Common Carotid Artery Internal Carotid Artery/External Carotid
Artery
o Subclavian Artery
Subclavian Artery:
o Chief arterial supply of upper limb and root of neck contributing branches to
head and brain
o Right artery is a branch of the innominate (branchiocephalic) artery whereas
left is a branch of the arch of the aorta
o Each artery enters neck behind corresponding sternoclavicular joint, curves
upwards for one inch above clavicle (half an inch below apex of the lung) to
end at the outer (lateral) border of the first rib behind the mid clavicular point
where it becomes the axillary artery
o The artery runs behind the scalenus anterior muscle which divides its course
into first, second and third parts
o 3 Parts of the Subclavian Artery as it Relates to the Scalenus Anterior:
Medial part has 3 branches vertebral, thyrocervical trunk and internal
thoracic
Posterior part has 2 branches, costocervical trunk and dorsal scapula
which may also arise from costocervical trunk
Lateral part has no branches
o Branches of the Vertebral Artery:
Grouped as cervical and intra-cranial branches
Cervical Branches:
Spinal branches (into each intervertebral foramen: second
part/segment)
Muscular branches
Intracranial Branches:
Meningeal arteries supply the dura mater of the posterior
cranial fossa
Posterior spinal arteries which descend along the medulla
oblongata
Anterior spinal arteries
Posterior inferior cerebellar artery (perhaps the most tortuous
artery in the body)
o Branches of First Part of the Subclavian Artery:
Thyrocervical Trunk:
Short, wide trunk that arises lateral to vertebral artery and from
upper surface of the subclavian artery and immediately breaks
into 3 branches
Transverse cervical artery
Suprascapular artery
Inferior thyroid artery (largest branch of the trunk)
o Passing between it and the internal carotid artery are from below and upwards,
the pharyngeal branch of the vagus (CN X), glossopharyngeal
o It lies on, below and upwards, the pharyngeal wall, superior laryngeal branch
of the vagus (CNX) and deep parotid lobe
o Branches:
Mostly arise in carotid triangle at different levels related to tip of the
greater horn of the hyoid bone
Ascending pharyngeal artery
Superior thyroid artery
Lingual artery
Facial artery
Occipital artery
Posterior auricular artery
Maxillary artery
Superficial temporal artery
o Anatomically before the ECA enters the parotid gland, the ECA gives off six
branches, three from in front, one from behind and one deep (medial)
Three in front are superior thyroid, lingual and facial
Two from behind are occipital and posterior auricular
One from medial is ascending pharyngeal
o Ascending Pharyngeal Artery:
Arises from medial side of external carotid, close to its origin, ascends
along the side of pharynx deep to the carotid sheath to reach the base
of the skull. Alongside the ICA (deep) and in front of the prevertebral
fascia
Branches:
Pharyngeal branches
Tonsillar branches
Inferior tympanic branch
Meningeal branches
o Superior Thyroid Artery:
Arises from anterior surface of external carotid (near commencement)
just below tip of greater horn of the hyoid bone, descends almost
vertically downwards with the vein to the upper pole of the thyroid
gland. Close behind it is the external laryngeal nerve
Branches:
Infra-hyoid artery
Superior laryngeal artery
Sterno-mastoid branches to the sterno-mastoid muscle
Crico-thyroid artery runs along the cricothyroid muscle and
membrane anastomosing with the opposite side
o Lingual Artery:
Arises from anterior surface of external carotid artery opposite the tip
of the greater horn of the hyoid bone above the superior thyroid artery
Forms short upward loop, then passes forwards along the upper b order
of the greater horn of the hyoid bone, deep to the hyoglossus muscle
before it enters the submandibular region
Its course is divided into three parts, relative to the hyoglossus muscle
First Part:
Runs in carotid triangle which it leaves by crossing deep to the
digastric muscle to enter the submandibular region
Branches:
o Small, supra-hyoid artery runs along the upper border of
the hyoid bone to anastomose with the opposite side
Second Part:
Runs horizontally under cover of the hyoglossus muscle along
the upper border of the hyoid bone with the lingual vein
Branches:
o 1-2 dorsalis lingulae arteries supply the dorsum of the
tongue, the palate and the tonsils
Third Part:
Ascends upwards under anterior border of hyoglossus between
it and the genioglossus towards tip of the tongue where it
becomes the deep artery of the tongue
Branches:
o Deep artery of the tongue (deep lingual artery)
o Sublingual artery which supplies the sublingual salivary
gland and gums anastomosing with the submental artery
o Facial Artery:
Arises in carotid triangle from anterior surface of ECA above the
lingual artery above the tip of the greater horn of the hyoid bone
Leaves carotid region, running upwards on the superior constrictor,
deep to the digastric and stylohyoid muscles to enter the submandibular region deep to the submandibular salivary gland. It indents
the surface of the gland
Makes S-bend, curling down over submandibular gland and up over
the mandible. Reaching the lower border of the mandible it hooks
around it (its pulsation can be felt 2.5cm in front of the angle of the
mandible at the anterior border of the masseter). It thus enters the face
at the antero-inferior angle of the masseter muscle where it ascends
upwards, forwards and medially towards the angles of the mouth, the
nose and the eye where it ends by anastomosing with the dorsal nasal
branches of the ophthalmic artery
Course of the artery is tortuous so that it can accommodate itself to the
movements of the pharynx during deglutition and the mandible during
opening of the mouth
Can be considered to be of two parts, cervical and facial
Infra-Orbital Artery:
Continuation of the maxillary artery, enters the orbit through
the inferior orbital fissure occupying the infra-orbital notch,
groove and canal which carries it to the face where it leaves the
skull through the infraorbital foramen
Throughout its course the artery is accompanied by the
infraorbital nerve and both run in the floor of the orbital cavity
Branches:
o Zygomatic branch, divides into zygomaticofacial and
zygomaticotemporal branches
o Middle superior alveolar artery supplies the sockets of
the premolar teeth and their pulp spaces
o Orbital branches to the contents of the orbit
o Anterior superior alveolar artery supplies the socket and
pulp spaces of the canine and incisors
o Terminal palpebral, nasal and labial
Circle of Willis:
o Anterior cerebral artery (left and right)
o Anterior communicating artery
o Internal carotid artery (left and right)
o Posterior cerebral artery (left and right)
o Posterior communicating artery (left and right)
Blood Vessels:
o Arteries and veins have same basic structure:
Intima (single layer of endothelium)
Media (muscular) with inner and outer elastic lamina
Adventitia (connective tissue)
o Veins less muscular and elastic
o Veins contain valves
Veins:
o Passively return blood to the heart
o In some instances can actively pulp blood (e.g. deep calf veins and pterygoid
venous plexus via use of muscle pump)
o Controls venous return and therefore cardiac output via nervous and chemical
signalling
Veins of the Head and Neck:
o Internal and External Jugular Systems:
Drain blood from deep and superficial structures
Venous return to the heart
Systems not exclusive to each other (points of communication are
clinically important)
Few valves
Some veins are encased in bone
o External Jugular System:
Formed by union of posterior auricular vein and posterior division of
retromandibular vein behind the angle of the mandible
Runs superficially across the sternocleidomastoid
Runs deep to the platysma and pierces the deep fascia of the neck in
the posterior triangle to enter the subclavian vein
Valves about 4cm about the subclavian
External Jugular Vein:
Drains most of scalp and the face Superficial temporal vein is
joined by maxillary veins (from pterygoid venous plexus) to
form the retromandibular vein
Just above the clavicle the external jugular vein also receives
the transverse cervical vein, suprascapular vein and anterior
jugular vein
Tributaries:
o Retromandibular vein
Superficial temporal vein
Maxillary veins
o Posterior auricular vein
o Transverse cervical vein
o Suprascapular vein
o Anterior jugular vein
o Facial Vein:
Supraorbital and suptratrochlear veins pass medial to the medial
canthus of the eyelids to form the angular vein
The angular vein continues as the facial vein
Accompanies the facial artery as it crosses the lower border of the
mandible
Then pierces investing fascia of the neck and is joined by anterior
division of the retromandibular
Tributaries:
Angular vein (supraorbital and suptratrochlear veins)
External nasal vein
Superior labial vein
Inferior labial vein
Anterior branch of retromandibular vein
Submental vein
Sometimes lingual vein and superior thyroid vein
o Lingual Vein:
Joins IJV at level of hyoid
May join IJV directly or have a common trunk with facial vein
Tributaries:
Dorsal lingual vein
Deep lingual vein (from tip of tongue, runs along under surface
of tongue)
Sublingual vein (joins deep lingual vein at anterior border of
hyoglossus to form the venae commitans of the hypoglossal
nerve). Drains either into lingual, facial or internal jugular vein
o Thyroid Veins:
Superior thyroid vein:
Exits upper pole of gland with artery
Drains into IJV or facial vein
Middle thyroid vein:
Short and wide
Drains into IJV
Inferior thyroid vein:
Forms a plexus on pretracheal fascia
Drains into brachiocephalic vein and/or IJV
o Retromandibular Vein:
Tributaries:
Superficial temporal vein
Maxillary veins
Runs down within parotid gland and drains it
Divides into anterior and posterior branches. Posterior branch joins
posterior auricular vein to form the EJV whereas anterior branch joins
facial vein to drain into the IJV
o Include:
Superior sagittal sinus:
Midline between layers of falx cerebri
From foramen caecum to internal occipital protuberance
Usually turns right into lateral (transverse) sinus
Inferior sagittal sinus:
From above crista galli back to free margin of falx cerebri
Flows into straight sinus where falx meets tentorium cerebelli
Straight sinus:
From inferior sagittal IOP
Slopes down at 45o
Turns left to form transverse sinus
Tributaries:
o Inferior sagittal sinus
o Cerebral veins
o Great cerebral vein of Galen
o Veins from occipital lobe and cerebellum
Transverse sinus:
From IOP runs between layers of tentorium cerebelli
Right usually larger
Runs forwards then downwards to become sigmoid sinus.
Superior petrosal sinus ends at this turn
Confluence of sinuses
Sigmoid sinus:
Exits at jugular foramen to become the internal jugular vein
Tributaries:
o Transverse sinus
o Occipital sinus
o Superior petrosal sinus
Occipital sinus
Basilar sinus
Cavernous sinus:
Adjacent to body of sphenoid bone
Middle cranial fossa
Contains internal carotid artery, abducens nerve, oculomotor
nerve, trochlear nerve (ophthalmic and maxillary branches)
Receives blood from orbit, skull and cerebral hemispheres
Tributaries:
o Ophthalmic veins
o Superficial middle cerebral veins
o Sphenoparietal vein
o Superior petrosal sinus
o Inferior petrosal sinus
o Pterygoid venous plexus
Drains Via:
o Superior petrosal sinus
o Inferior petrosal sinus
o Small veins to pterygoid venous plexus
Superior petrosal sinus
Inferior petrosal sinus
Cavernous Sinus Thrombosis:
o Facial infection can produce thrombosis
o Spread of infection via valveless veins
o Painful ophthalmoplegia
o Retrograde thrombosis of inferior petrosal sinus and medullary veins is usually
fatal
Central/Peripheral Venous Communications:
o Facial vein and cavernous sinus Angular vein communicates with superior
ophthalmic vein
o Deep facial vein and cavernous sinus Via pterygoid venous plexus
o Posterior auricular vein and sigmoid sinus Via mastoid emissary vein,
mastoiditis can lead to temporal abscess, meningitis, encephalitis, retrograde
thrombosis and death
Lymph Nodes:
o Lymph transports foreign material to nodes
o Initiation of immune response
o Principally B cells but T cells help
o Innate immune cells also involved
o Enlarge when active
o May be affected by disease:
Reaction to infection
Abscess
Cancer (primary or metastatic)
Granuloma
o Enlarged lymph nodes may:
Indicate presence of infection
Indicate presence of neoplasia
Indicate primary site of either based on knowledge of normal
lymphatic drainage
Lymphatics of Head and Neck:
o No lymphatics in following systems:
Central nervous system
Globe
Inner ear
Cartilage
Bone
Epidermis
o Eventually all lymphs from the head and neck pass through the deep cervical
nodes eventually draining into the thoracic duct (drains whole body except
upper right limb, right thorax, right head and neck), right lymphatic duct and
subclavian vein
o Occipital Nodes:
Apex of posterior triangle
Drains posterior scalp
o Supraclavicular Nodes:
Numerous nodes above clavicle
Outlying deep cervical nodes
o Deep Cervical Nodes:
Lie in loose connective tissue around internal jugular vein
Posterior group pass under sternocleidomastoid to become
supraclavicular group
Parotid drains via upper cervical group
Orbit drains to pre-auricular and then parotid nodes and then to upper
deep cervical nodes
o Submental Nodes:
3-4
Below chin
Drain to submandibular nodes
Drain anterior floor of mouth, lower incisors, lower anterior gingivae,
lower lip and tip of tongue
o Submandibular Nodes:
6 or so
Within and on surface of submandibular gland
Remove gland if treating nodal metastatic disease
Drains submental nodes, lateral of lower lip, external nose, anterior 2/3
of the tongue, anterior nasal walls, paranasal sinus, all other teeth and
submandibular gland
o Retropharyngeal Nodes:
Drain posterior nasal cavity, posterior ethmoidal sinus, sphenoidal
sinus and pharynx
o Jugulodigastric Nodes:
Drain tonsil
Just below angle of mandible
o Tongue Lymphatic Drainage:
Anterior to submental lymph nodes
Lateral to submandibular lymph nodes
Centre to inferior deep cervical lymph nodes
Posterior to deep cervical lymph nodes
o Contents:
Above posterior belly of the digastric it contains the ICA
anteromedially, the IJV posterolaterally and CN IX to XII in between
Below the digastric it contains the CCA and the lower part of the ICA
as well as the IJV with the vagus nerve only in between
The limbs of the ansa cervicalis and its loop are embedded on the
anterior wall of the sheath whereas the sympathetic chain is embedded
lengthwise along the posterior wall of the sheath
Pre-Tracheal Fascia:
o Well-formed membrane on which the infra-hyoid muscles can move during
movements of larynx and pharynx
o Attachments:
Above To hyoid bone and oblique line of thyroid cartilage
Below Fascia extends behind sternum around the inferior thyroid
veins to blend with fibrous pericardium and adventitia of the aortic
arch
o Split to enclose the thyroid gland, fixing it to the larynx and the 2nd, 3rd and 4th
tracheal rings. Its anterior surface is blended to the fascial sheaths of the infrahyoid muscles
Pre-Vertebral Fascia:
o Tough, fibrous membrane that lies in front of the prevertebral muscles forming
a base on which the pharynx, oesophagus and carotid sheaths move during
swallowing
o Attachments:
Medially Fascia continuous across the median plane with other side
blending with the anterior longitudinal ligament of the vertebral
column
Sideways Fascia is continuous deep to the carotid sheath and the
sternomastoid muscle with the deep fascia covering the floor of the
posterior triangle
Above Fascia fixed to base of the skull
Below Extends to superior mediastinum to be attached to the 3rd
thoracic vertebra
Pharyngeal Fascia:
o Bucco-Pharyngeal Fascia - Covers outer surface of pharyngeal muscles and is
prolonged anteriorly over the buccinator muscle
o Pharyngo-Basilar Fascia Tough, fibrous membrane that fills gap between the
upper border of the pharynx and base of the skull. Pierced by Eustachian tube
and palatal muscles
o Retro-Pharyngeal Fascia Forms a loose areolar tissue between posterior wall
of the pharynx, oesophagus and the prevertebral fascia allowing their free
movement
Odontogenic Infections:
o Spread to Primary Spaces:
Sinus
Nasal cavity
Palate
Sublingual
Submandibular
Vestibular
Buccal
o Spread to Secondary Spaces:
Pterygomandibular Between medial and lateral pterygoid muscles
Masseteric Spreads from submandibular and buccal
Superficial and deep temporal
Infratemporal space
Lateral pharyngeal space Migrates from Pterygomandibular space
and contains many vital structures
Retropharyngeal
Prevertebral Danger Space 4 between prevertebral and alar
extension
Grodinsky and Holyoke spaces