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IndustryARC

Global Cryotherapy and Cryosurgery Market

(2014-2020)

By Type (Cryosurgery, Ice Pack Therapy and Cryogenic Chamber Therapy), By

Technique (Spray, Forceps, Cryo Probe And Others); By Device (Cryogun, Probes,
Cryogen And Others), By Application (Cancer Therapy and Skin Disease) and By
Geography

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Table of Contents
1. Global Cryotherapy and Cryosurgery Market - Market Overview
2. Executive Summary
3. Global Cryotherapy and Cryosurgery Market - Market Landscape
3.1. Market Share Analysis
3.2. Comparative Analysis
3.2.1.

Product Benchmarking

3.2.2.

End user profiling

3.2.3.

Patent Analysis

3.2.4.

Top 5 Financials Analysis

4. Global Cryotherapy and Cryosurgery Market Market Forces

4.1. Market Drivers
4.2. Market Constraints
4.3. Market Challenges
4.4. Attractiveness of the Global Cryotherapy and Cryosurgery Market
4.4.1.

Power of Suppliers

4.4.2.

Power of Customers

4.4.3.

Threat of New entrants

4.4.4.

Threat of Substitution

4.4.5.

Degree of Competition

5. Global Cryotherapy and Cryosurgery Market Strategic Analysis

5.1. Value Chain Analysis
5.2. Pricing Analysis
5.3. Opportunities Analysis
5.4. Product/Market Life Cycle Analysis

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5.5. Suppliers and Distributors

6. Global Cryotherapy and Cryosurgery Market By Type of Cryotherapy
6.1. Cryosurgery
6.2. Icepack therapy
6.3. Cryogenic chamber therapy
7. Global Cryotherapy and Cryosurgery Market - By Application Technique
7.1. Spray Technique
7.2. Dipstick applicator Type of Cryogen
7.3. Cryo probe
7.4. Thermo-couple device
7.5. Forceps Technique
7.6. Others
8. Global Cryotherapy and Cryosurgery Market - Cryosurgery By Type of cryogen
8.1. Liquid Nitrogen
8.2. Carbon dioxide
8.3. Argon
8.4. Dimethyl ether-propane
8.5. Others
9. Global Cryotherapy and Cryosurgery Market - By Disease Area Application
9.1. Introduction
9.2. Cancer Therapy
9.3. Cardiovascular Disease
9.4. Skin Disease
9.5. Gynaecological Disease
9.6. Other General Surgery

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10. Global Cryotherapy and Cryosurgery Market - By Major Device Types

10.1.

Introduction

10.2.

Cryogun/ Spray gun

10.3.

Gas Pressure Gauge

10.4.

Probes

10.5.

Cryogen

10.6.

Liquid Dewar/Gas Cylinder

10.7.

Others

11. Global Cryotherapy and Cryosurgery Market - Geographic Analysis

11.1.

Introduction

11.2.

North America
11.2.1. U.S.
11.2.2. Canada
11.2.3. Mexico

11.3.

Asia-Pacific
11.3.1. China
11.3.2. Japan
11.3.3. Singapore
11.3.4. Others

11.4.

Europe
11.4.1. Germany
11.4.2. U.K
11.4.3. France
11.4.4. Others

11.5.

ROW

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12. Global Cryotherapy and Cryosurgery Market- Market Entropy

12.1.

New Product Launches

12.2.

M&As, Collaborations, JVs and Partnership

13. Company Profiles (Overview, Financials, SWOT Analysis, Developments, Product Portfolio)
13.1.

Cryoalfa Europe

13.2.

CryoCOncepts LP

13.3.

Mectronic Medicale srl

13.4.

Wallach Surgical Devices

13.5.

Medtronic

13.6.

CryoProbe

13.7.

Cortex Technology

13.8.

Brymill Cryogenics Systems

13.9.

Erbe medical

13.10. Metrum Cryoflex

13.11. MedGyn
13.12. CoolTouch Inc.
13.13. Optikon
13.14. Uzumcu
13.15. SMT medical
13.16. Cryonic
13.17. Inomed
13.18. Zimmer Medizin Systeme
13.19. Gbo Medizintechnik AG
13.20. Physio med
13.21. HIRONIC

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14. Appendix
14.1.

Abbreviations

14.2.

Sources

14.3.

Research Type of Cryogen ology

14.4.

Bibliography

14.5.

Compilation of Expert Insights

14.6.

Disclaimer

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LIST OF TABLES
Table 1 Global Cryotherapy and Cryosurgery, List of Companies Covered
Table 2 Global Cryotherapy and Cryosurgery Market Competitive Share Analysis, 2013 (%)
Table 3 Top 5 Market Players Financials Analysis
Table 4 Global Cryotherapy and Cryosurgery Market Revenue, 2014 2020 ($M)
Table 5 Global Cryotherapy and Cryosurgery Market Revenue, By Application technique,
2014 2020 ($M)
Table 6 Global Cryotherapy and Cryosurgery Market Revenue, By Type of Cryotherapy,
2014 2020 ($M)
Table 7 Global Cryotherapy and Cryosurgery Market Revenue, By Type of Cryogen, 2014
2020 ($M)
Table 8 Global Cryotherapy and Cryosurgery Market Revenue, By Disease Area Application,
2014 2020 ($M)
Table 9 Global Cryotherapy and Cryosurgery Market Revenue, By Major Device Type, 2014
2020 ($M)
Table 10 Average Selling Price Analysis, Cryotherapy and Cryosurgery, 2014 2020 ($M)
Table 11 Cryotherapy and Cryosurgery Market Revenue in Cancer Therapy, By Application
Technique, 2014 2020 ($M)
Table 11 Cryotherapy and Cryosurgery Market Revenue in Cancer Therapy, By Type of
Cryogen, 2014 2020 ($M)
Table 12 Cryotherapy and Cryosurgery Market Revenue in Cancer Therapy, By Major Device
Type, 2014 2020 ($M)
Table 13 Cryotherapy and Cryosurgery Market Revenue in Cardiovascular Diseases, By
Application Technique, 2014 2020 ($M)
Table 14 Cryotherapy and Cryosurgery Market Revenue in Cardiovascular Diseases, By Type
of Cryogen, 2014 2020 ($M)
Table 15 Cryotherapy and Cryosurgery Market Revenue in Cardiovascular Diseases, By
Major Device Type, 2014 2020 ($M)
Table 16 Cryotherapy and Cryosurgery Market Revenue in Skin Disease, By Application
Technique, 2014 2020 ($M)
Table 17 Cryotherapy and Cryosurgery Market Revenue in Skin Disease, By Type of
Cryogen, 2014 2020 ($M)
Table 18 Cryotherapy and Cryosurgery Market Revenue in Skin Disease, By Major Device
Type, 2014 2020 ($M)
Table 19 Cryotherapy and Cryosurgery Market Revenue in Gynaecological Disease, By
Application Technique, 2014 2020 ($M))

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Table 20 Cryotherapy and Cryosurgery Market Revenue in Gynaecological Disease, By Type

of Cryogen, 2014 2020 ($M)
Table 21 Cryotherapy and Cryosurgery Market Revenue in Gynaecological Disease, By Major
Device Type, 2014 2020 ($M)
Table 22 Cryotherapy and Cryosurgery Market Revenue in Other General Surgery, By Type
of Cryogen, 2014 2020 ($M)
Table 23 Cryotherapy and Cryosurgery Market Revenue in Other General Surgery, By
Application Technique, 2014 2020 ($M)
Table 24 Cryotherapy and Cryosurgery Market Revenue in Other General Surgery, By Major
Device Type, 2014 2020 ($M)
Table 25 Cryotherapy and Cryosurgery Market Revenue in Cryogun/Spray gun, By Disease
Area Application, 2014 2020 ($M)
Table 26 Cryotherapy and Cryosurgery Market Revenue in Gas Pressure Gauge, By Disease
Area Application, 2014 2020 ($M)
Table 27 Cryotherapy and Cryosurgery Market Revenue in Probes, By Disease Area
Application, 2014 2020 ($M)
Table 28 Cryotherapy and Cryosurgery Market Revenue Cryogen, By Disease Area
Application, 2014 2020 ($M)
Table 29 Cryotherapy and Cryosurgery Market Revenue in Liquid Dewar/Gas Cylinder, By
Disease Area Application, 2014 2020 ($M)
Table 30 Cryotherapy and Cryosurgery Market Revenue in Others, By Disease Area
Application, 2014 2020 ($M)
Table 31 Cryotherapy and Cryosurgery Market Revenue in Cryogun/Spray gun, By Type of
Cryogen, 2014 2020 ($M)
Table 32 Cryotherapy and Cryosurgery Market Revenue in Gas Pressure Gauge, By Type of
Cryogen, 2014 2020 ($M)
Table 33 Cryotherapy and Cryosurgery Market Revenue in Probes, By Type of Cryogen,
2014 2020 ($M)
Table 34 Cryotherapy and Cryosurgery Market Revenue Cryogen, By Type of Cryogen, 2014
2020 ($M)
Table 35 Cryotherapy and Cryosurgery Market Revenue in Liquid Dewar/Gas Cylinder, By
Type of Cryogen, 2014 2020 ($M)
Table 36 Cryotherapy and Cryosurgery Market Revenue in Others, By Type of Cryogen,
2014 2020 ($M)
Table 37 Cryotherapy and Cryosurgery Market Revenue in Cryogun/Spray gun, By
Application Technique, 2014 2020 ($M)
Table 38 Cryotherapy and Cryosurgery Market Revenue in Gas Pressure Gauge, By
Application Technique, 2014 2020 ($M)

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Table 39 Cryotherapy and Cryosurgery Market Revenue in Probes, By Application

Technique, 2014 2020 ($M)
Table 40 Cryotherapy and Cryosurgery Market Revenue Cryogen, By Application Technique,
2014 2020 ($M)
Table 41 Cryotherapy and Cryosurgery Market Revenue in Liquid Dewar/Gas Cylinder, By
Application Technique, 2014 2020 ($M)
Table 42 Cryotherapy and Cryosurgery Market Revenue in Others, By Application
Technique, 2014 2020 ($M)
Table 43 Cryotherapy and Cryosurgery Market Revenue in Liquid Nitrogen, By Application
Technique, 2014 2020 ($M)
Table 44 Cryotherapy and Cryosurgery Market Revenue in Carbon Dioxide, By Application
Technique, 2014 2020 ($M)
Table 45 Cryotherapy and Cryosurgery Market Revenue in Argon, By Application
Technique, 2014 2020 ($M)
Table 46 Cryotherapy and Cryosurgery Market Revenue in Dimethyl ether-propane By
Application Technique, 2014 2020 ($M)
Table 47 Cryotherapy and Cryosurgery Market Revenue in Others, By Application
Technique, 2014 2020 ($M)
Table 48 Cryotherapy and Cryosurgery Market Revenue in Liquid Nitrogen, By Disease Area
Application, 2014 2020 ($M)
Table 49 Cryotherapy and Cryosurgery Market Revenue in Carbon Dioxide, By Disease Area
Application, 2014 2020 ($M)
Table 50 Cryotherapy and Cryosurgery Market Revenue in Argon, By Disease Area
Application, 2014 2020 ($M)
Table 51 Cryotherapy and Cryosurgery Market Revenue in Dimethyl ether-propane, By
Disease Area Application, 2014 2020 ($M)
Table 52 Cryotherapy and Cryosurgery Market Revenue in Others, By Disease Area
Application, 2014 2020 ($M)
Table 53 Cryotherapy and Cryosurgery Market Revenue in Liquid Nitrogen, By Major
Device Types, 2014 2020 ($M)
Table 54 Cryotherapy and Cryosurgery Market Revenue in Carbon Dioxide, By Major
Device Types, 2014 2020 ($M)
Table 55 Cryotherapy and Cryosurgery Market Revenue in Argon, By Major Device Types,
2014 2020 ($M)
Table 56 Cryotherapy and Cryosurgery Market Revenue in Dimethyl ether-propane, By
Major Device Types, 2014 2020 ($M)
Table 57 Cryotherapy and Cryosurgery Market Revenue in Others, By Major Device Types,
2014 2020 ($M)

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Table 58 Cryotherapy and Cryosurgery Market Revenue in Spray Technique, By Major

Device Types, 2014 2020 ($M)
Table 59 Cryotherapy and Cryosurgery Market Revenue in Dipstick applicator method, By
Major Device Types, 2014 2020 ($M)
Table 60 Cryotherapy and Cryosurgery Market Revenue in Cryo probe, By Major Device
Types, 2014 2020 ($M)
Table 61 Cryotherapy and Cryosurgery Market Revenue in Thermo-couple device, By Major
Device Types, 2014 2020 ($M)
Table 62 Cryotherapy and Cryosurgery Market Revenue in Forceps technique, By Major
Device Types, 2014 2020 ($M)
Table 63 Cryotherapy and Cryosurgery Market Revenue in Others, By Major Device Types,
2014 2020 ($M)
Table 64 Cryotherapy and Cryosurgery Market Revenue in Spray Technique, By Disease Area
Application, 2014 2020 ($M)
Table 65 Cryotherapy and Cryosurgery Market Revenue in Dipstick applicator method, By
Disease Area Application, 2014 2020 ($M)
Table 66 Cryotherapy and Cryosurgery Market Revenue in Cryo probe, By Disease Area
Application, 2014 2020 ($M)
Table 67 Cryotherapy and Cryosurgery Market Revenue in Thermo-couple device By Disease
Area Application, 2014 2020 ($M)
Table 68 Cryotherapy and Cryosurgery Market Revenue in Forceps technique, By Disease
Area Application2014 2020 ($M)
Table 69 Cryotherapy and Cryosurgery Market Revenue in Others, By Disease Area
Application, 2014 2020 ($M)
Table 64 Cryotherapy and Cryosurgery Market Revenue in Spray Technique, By Type of
Cryogen, 2014 2020 ($M)
Table 65 Cryotherapy and Cryosurgery Market Revenue in Dipstick applicator method, By
Type of Cryogen, 2014 2020 ($M)
Table 66 Cryotherapy and Cryosurgery Market Revenue in Cryo probe, By Type of Cryogen,
2014 2020 ($M)
Table 67 Cryotherapy and Cryosurgery Market Revenue in Thermo-couple device, By Type
of Cryogen, 2014 2020 ($M)
Table 68 Cryotherapy and Cryosurgery Market Revenue in Forceps technique, By Type of
Cryogen, 2014 2020 ($M)
Table 69 Cryotherapy and Cryosurgery Market Revenue in Others, By Type of Cryogen,
2014 2020 ($M)
Table 70 Europe Cryotherapy and Cryosurgery Market Revenue, 2014 2020 ($M)

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Table 71 Asia-Pacific Cryotherapy and Cryosurgery Market Revenue, 2014 2020 ($M)
Table 72 M&A, JV, Agreements, Cryotherapy and Cryosurgery Industry

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LIST OF FIGURES
Figure 1 Segmentation of Cryotherapy and Cryosurgery Market, By Product Type
Figure 2 Segmentation of Cryotherapy and Cryosurgery Market, By Type of Cryogen
Figure 3 Segmentation of Cryotherapy and Cryosurgery Market, By Application Technique
Figure 4 Segmentation of Cryotherapy and Cryosurgery Market, By Major Device Type
Figure 5 Cryotherapy and Cryosurgery Market, List of Companies Covered
Figure 6 Global Cryotherapy and Cryosurgery Market Competitive Share Analysis, 2014 (%)
Figure 7 Global Cryotherapy and Cryosurgery Market Revenue, 2014 - 2020 ($bn)
Figure 8 Average Selling Price Analysis of Cryotherapy and Cryosurgery, 2014 2020 ($)
Figure 9 Global Cryotherapy and Cryosurgery Market Revenue, By Application Technique,
2014 (%)
Figure10 Global Cryotherapy and Cryosurgery Market Revenue, By Type of Cryogen, 20142020 ($M)
Figure11 Global Cryotherapy and Cryosurgery Market Revenue, By Major Device Type,
2014-2020 ($M)
Figure12 Global Cryotherapy and Cryosurgery Market Revenue, By Geographic Region,
2014 2020 ($M)

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REPORT SCOPE
The Global Cryotherapy and Cryosurgery Market has been segmented into different
categories, based on application technique, cryogen used, disease area application and major
device types. Each of these segments is further broken down into sub-segments give an indepth analysis of the market.
The overall market is also presented from the perspective of different geographic regions and
the key countries for this industry. Competitive landscape for each of the product types is
highlighted and market players are profiled with attributes of company overview, financial
overview, business strategies, product portfolio and recent developments. Market shares of
the key players for 2012 are provided. The prominent players profiled in this report are
Cryoalfa Europe Ltd, CryoConcepts LP, Mectronic Medicale S.R.L, Wallach Surgical Devices,
Medtronic, CryoProbe, Cortex Technology and Brymill Cryogenics Systems. The report
contains the most detailed and in-depth segmentation of the global Cryotherapy and
Cryosurgery Market.

STAKEHOLDERS
Following are the key stakeholders of this market:
Product OEMs
Contract manufacturers
Service providers
Component suppliers
Health care professionals
Health care companies

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EXECUTIVE SUMMARY
Cryotherapy is the process of using low temperatures for medical therapy; this refers to all the
procedures that are both destructive and non-destructive. Cryosurgery is a type of
Cryotherapy, wherein deceased or abnormal tissues are destroyed using low temperatures, this
is a destructive procedure performed using an openly surgical approach. This is used primarily
to treat cancers such as retinoblastoma, basal cell and squamous cell carcinoma, prostate
cancer and cervical cancer.
Dermatologists have been using Cryotherapy for various purposes such as to treat skin tags,
nodules, pre-cancerous skin moles etc., since the turn of the century. With the development
of the vacuum flask to store sub-zero liquid elements, such as nitrogen, oxygen and hydrogen,
the use of Cryotherapy increased exponentially. Being a minimally invasive procedure,
Cryosurgery is preferred over open surgeries, thereby boosting the Cryosurgery market.
Moreover, as the application is localized, healthy tissue is maintained. This minimises side
effects for the healthy tissue.
Cryosurgery is also a favourable solution, in case wherein an individual has to be subjected to
multiple treatments. It can safely be used alongside other standard treatment options such as
surgery, chemotherapy, hormone therapy and radiation. Furthermore, cryosurgery is a feasible
option for candidates who are not suitable for conventional surgery due to their age or any
other medical condition.

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SAMPLE TABLE: GLOBAL CRYOTHERAPY AND CRYOSURGERY, BY

APPLICATION, 2014-2020 ($M)
Application

2014

2015

2016

2017

2019

2020

Cancer Therapy

xx

xx

xx

xx

xx

xx

CAGR%
(20152020)
xx%

Cardiovascular
Disease
Skin Disease

xx

xx

xx

xx

xx

xx

xx%

xx

xx

xx

xx

xx

xx

xx%

Gynecological
Disease
Other General
Surgery
Total

xx

xx

xx

xx

xx

xx

xx%

xx

xx

xx

xx

xx

xx

xx%

xx

xx

xx

xx

xx

xx

xx%

Source: Industry ARC analysis.

The global Cryotherapy and Cryosurgery Market is estimated to grow at a CAGR of xx%
during the forecast period 2014-2020, from $xx M in 2014 to reach $xx M by 2020.

SAMPLE TABLE: GLOBAL CRYOTHERAPY AND CRYOSURGERY MARKET

REVENUE, BY REGION, 2014-2020 ($M)
Region

2014

2015

2016

2017

2019

2020

North
America
APAC

xx

xx

xx

xx

xx

xx

CAGR%
(20152020)
xx%

xx

xx

xx

xx

xx

xx

xx%

Europe

xx

xx

xx

xx

xx

xx

xx%

ROW

xx

xx

xx

xx

xx

xx

xx%

Total

xx

xx

xx

xx

xx

xx

xx%

Source: Industry ARC analysis

This report focuses on the Cryotherapy and Cryosurgery market opportunities and growth
prospects. The market has been segmented by geography as North America, Europe, AsiaPacific, and Rest of the World (RoW). Out of these regions, North America and Europe are
the regions that account for the majority of market share in the global Cryosurgery market.
Some of the major factors driving the demand in these regions are well-developed healthcare

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sector that is equipped with latest technologies, trained healthcare professionals, and evergrowing disposable income together with favourable reimbursement policies. With rapid
development in the economies of Asia-Pacific region, healthcare sector is projected to
become more sophisticated which will lead to an increased demand in the Cryotherapy and
Cryosurgery market.
Market size and forecast are provided for each of these regions. A detailed qualitative analysis
of the factors responsible for driving and restraining growth of the Cryotherapy and
Cryosurgery market and future opportunities are provided in the report. This report on the
Global Cryotherapy and Cryosurgery Market identifies many such insights and M&A
opportunities, besides providing a detailed analysis of the Cryotherapy and Cryosurgery
market.

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3. GLOBAL CRYOTHERAPY AND CRYOSURGERY MARKETMARKET LANDSCAPE

3.1 MARKET SHARE ANALYSIS
Market share of all the major players of Cryotherapy and Cryosurgery market are analysed in
this section.

SAMPLE TABLE: GLOBAL CRYOTHERAPY AND CRYOSURGERY MARKET,

COMPETITIVE SHARE ANALYSIS, 2013 (%)
Company
Brymill Cryogenics Systems
Cryoalfa Europe Ltd.
CryoCOncepts LP
Mectronic Medicale srl
Wallach Surgical Devices
Others

Market Share (%)

xx%
xx%
xx%
xx%
xx%
XX%

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KEY MARKET INSIGHTS

According to the World Cancer Report 2014, published by the World Health
Organization (WHO), approximately 14 million new cancer cases were reported in 2012
and this number is expected to increase to 22 million per year in the next 20 years
Cancer mortality is estimated to increase from around 8.2 million per year to 13 million
per year over the same period, thus increasing the global cancer burden by 70 %
Incidence rates remain highest in the developed nations but mortality is relatively higher
in developing nations due to lack of early detection and limited access to healthcare
Cryosurgery is less invasive compared to other cancer treatment options, thereby
minimizing surgical complications such as pain and bleeding
Cryosurgery requires shorter hospital stays; for instance, in the case of prostate cancer,
according to HCFA (Health Care Financing Administration), the cost of prostate cancer
cryosurgery is approximately $13,500 as compared to that of $14,200 for brachytherapy
and$15,000 for external beam radiation
According to the recent study, the combination of intralesional cryosurgery with topical
silicone gel sheeting is useful in the treatment of refractory keloids

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RESEARCH METHODOLOGY
The quantitative and qualitative data collected for the Cryotherapy and Cryosurgery market
report is from a combination of secondary and primary sources. Research interviews were
conducted with senior executives and/or managers of leading Cryotherapy and Cryosurgery
solution providers. These Key Opinion Leaders (KOLs) were then provided a questionnaire to
gather quantitative and qualitative inputs on their operations, performance, strategies and views
on the overall market, including key developments and technology trends. Data from interviews
is consolidated, checked for consistency and accuracy, and the final market numbers are again
validated by experts. The global market was split by products, disease area and geography based
on different factors like primary and secondary sources, understanding of the number of
companies operating in each segment and also KOL insights.
We have used various secondary sources such as directories, articles, white papers, newsletters,
annual reports and paid databases such as OneSource, Hoovers and Factiva to identify and
collect information for extensive technical and commercial study of the Cryotherapy and
Cryosurgery market.
The key players in the market and its value chain were identified through secondary research and
their market opinions were also gathered in a similar way through telephonic interviews and
questionnaires. We have also studied the annual reports of these top market players. Interviews
with key opinion leaders such as directors, managers, marketing personnel were used extensively
in understanding the need and emergence of Cryotherapy and Cryosurgery market.

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THE ARC ADVANTAGE

An analytical model lies at the core of our process, ensuring logical consistency
throughout our research. We complement the model with secondary data and
interviews with industry experts to reflect the latest trends. With our final expert
validation, we provide you with only the most accurate and actionable intelligence.

THE ARC PROCESS

Analytical
Method
1. Granular
breakdown of
drivers into
factors
2. Validate all
factors in terms
of their present
impact on the
market
3. Assign weights
to these factors in
terms of their
relevance and
impact on the
market
4. Build the
Analytical Model
ANALYTICAL MODEL

Base Method

1. Get a topdown estimate of

the market
2. Follow it up
with a bottom-up
estimate of the
market
3. Check
forconsistency
and new growth
factors that are
relevant over the
next 10 Years

4. Build the Base

model
BASE MODEL

Consolidation
Method
1. Granular
breakdown of
drivers into
factors
2. Validate all
factors in terms
of their present
impact on the
market.
3. Assign weights
to these factors in
terms of their
relevance and
impact on the
market.
4. Build the
Consolidated
Model

Delphi
Verification
1. Verify the
findings of the
model with
experts from
across the value
chain
2. Verify the
findings with
players across
small and large
enterprises
3. Tweak the
model and add
new factors
4. Finalize the
ARC Model

CONSOLIDATED MODEL

ARC MODEL

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