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UNIVERSITY OF SANTO TOMAS

Faculty of Pharmacy
An Outcomes-Based Teaching-Learning Program for MATH 600
2nd Semester, A.Y. 2014-2015
Course Title:
BIOSTATISTICS
Course Number: MATH 600
Credit Units:
Contact Hours:

3 units (2 lecture units, 1 laboratory unit)


2 lecture hours per week
2 laboratory hours per week

Course Placement:
Pre requisites:

Second Year (Pharmacy), Third Year (Medical Technology & Biochemistry)

College Algebra (Math 101) / Algebra and Trigonometry (Math 101a)

Course Facilitators:

Ninia I. Calaca, Xandro Nieto

Course Description:The Biostatistics course deals with the collection, organization, presentation, analysis, evaluation, interpretation,
formulation and testing of hypotheses and formulation of generalizations and inferences involving biological data, especially those concerning
health care, preventive medicine, clinical and laboratory tests.
The course enhances research knowledge, skills and values through the application of statistical principles, theories, methods and techniques
with the aid of recent and relevant computer statistical software in solving problems related to human health and the basic biological and
medical concerns.

Approved by:
Date of Approval:

Assoc. Prof. Ma. Elena J. Manansala


Dean
October 29, 2013
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INSTITUTIONAL INTENDED LEARNING


OUTCOME (IILO)
(GRADUATE ATTRIBUTES)
Academic Excellence
Show expertise in the competencies
necessary to the practice of profession.
Leadership and Teamwork
Demonstrate capacity for leadership and
teamwork including the ability to
motivate others, to be responsible and
reliable.
Critical Thinking, Research and Problem
Solving Skills
Initiate innovative ideas and methods
through research responsive to the
changing needs of the society.
Productivity and Accountability
Develop new knowledge and
understanding that will contribute to
nation-building and sustainable
development through the processes of
inquiry, research and innovation.
Social and Ethical Responsibility
Uphold Catholic values and moral
principles reflective of a competent,
committed and compassionate
Thomasian in the formation of humanely
progressive and healthy society.
Communication and Relational Skills
Develop effective communication
competencies through interpersonal

PROGRAM INTENDED LEARNING


OUTCOME
(PILO)
Demonstrate creative application of
concepts and methods in general
education geared towards the
advancement of various fields of
profession.
Exhibit capacity to contribute as productive
member of the profession and assume
leadership roles as appropriate in the
profession and society.

COURSE INTENDED LEARNING


OUTCOME(CILO)
1. Apply the appropriate statistical principles,
methods and techniques with the aid of
computer software in the analysis of data.
2. Work productively and harmoniously as
members of a group in a Biostatistics research
paper.

Demonstrate a repertoire of thinking


strategies that will enable them to acquire,
evaluate and synthesize information and
knowledge and develop analytical skills to
make decisions in both familiar and
unfamiliar situation.
Generate insights and new knowledge in
general education that will contribute to
nation-building and sustainable
development through processes of inquiry,
research and innovation.

3. Apply the appropriate statistical principles,


methods and techniques with the aid of
computer software in solving problems related
to human health and the basic biological and
medical concerns.

Develop Catholic value systems and ethical


standard that guide professional and social
behaviors reflective of the Thomasian
identity.

5. Observe ethical standards in conducting the


Biostatistics research.

Demonstrate communication competence


and relational skills essential to
professional practice and to continued

6. Prepare a research paper for presentation to


a panel of evaluators using effective
communication skills and the appropriate

4. Formulate and test hypotheses involving


health care, preventive medicine, clinical and
laboratory tests and generate inferences and
recommendations on scientific findings.

skills and utilize information technology


responsibly as an effective tool in

person and professional growth as well as


to informed citizenry.

information

exploring and expressing ideas.

Intended Learning Outcomes

Content

Teaching-Learning
Activities

Assessment Tasks

Unit I: Descriptive Statistics


Explain the meaning of the different statistical
terms.(CILO1)

Collect, organize and present data


appropriately to aid in solving problems related
to human health and the basic biological and
medical concerns.(CILO3)

1. Definition of statistical terms


1.1 Statistics
1.2 Biostatistics
1.3 Descriptive and Inferential Statistics
1.4 Types of data/Variable
1.5 Population and parameters
1.6 Samples and statistics

Interactive Lecture

Focused Listing

Assigned Reading

Compare and contrast chart

Work Along Activities

Categorizing Grid

2. Data Collection, Organization and Presentation


2.1 Collection Methods
2.2 Presentation Methods

Lecture Demonstration
Computer Hands-on Activity

Problem Sets

Brainstorming groups
Collaborative
learning/research
Web search

Work productively and harmoniously with


group mates in writing a research paper
starting from topic selection until its final
completion. (CILO2)
Describe and interpret data in terms of the
appropriate quantitative measures. (CILO1)

Content, Form, and Function


Outline

3. Quantitative measures
3.1central tendencies
3.2 dispersion
3.3 quantiles
3.4 skewness

Lecture Demonstration

Students Portfolio
Classroom Opinion Polls

Performance Assessment

Work Along Activities


3

3.5kurtosis

Intended Learning Outcomes

Content

Computer Hands-on Activity

Teaching-Learning Activities

Assessment Tasks

Interactive Lecture

Venn Diagram

Web-enhanced Drill

Problem Sets

Unit II: Introduction to Probability and


Hypotheses Testing
Solve probability problems with biological
significance. (CILO3)

Determine estimates and confidence limits for


the data collected to generate inferences and
provide recommendations to the solutions of
identified biological or health-related concerns.
(CILO4)

1. Probability
1.1 Experiment, Sample Space, Event, Probability,
Compound Probability, Conditional Probability
1.2 Bayes Theorem
1.3 Total Probability
2. Probability Distributions
2.1 Binomial
2.2 Poisson
2.3 Normal
3. *Essential statistics
3.1 ED50
3.2 IC50
3.3 LD50
3.4 Probit Analysis

Problem-Solving Learning

4.Central Limit theorem


5. Estimation
5.1 Point estimation
5.2 Confidence interval estimation

Interactive Lecture

Problem Recognition Tasks

Work along exercises

Whats the Principle


4

Intended Learning Outcomes

Content

Teaching-Learning Activities

Assessment Tasks

Lecture Demonstration

Whats the Principle

Collaborative
learning/research

Performance Assessment

Unit III: Statistical Inference


Formulate hypotheses and apply the basic
principles of hypothesis testing on data
involving health care, preventive medicine,
clinical and laboratory tests. (CILO4)

1. Introduction to Testing Hypothesis


1.1 Formulation of Hypothesis
1.2Steps in Testing Hypothesis
1.3 One-tailed and Two-tailed Testing

Pros and Cons Grid


Computer Hands-on Activity

Reflect on the implications of the conclusions


of the research output in relation to its
contribution to human health, health care and
drug design and development. (CILO4)

2. Hypothesis Testing of Continuous Data for One


Sample

Analytic Memos
Learning Partner
Critiques

3. Hypothesis Testing of Continuous Data for Two


Samples

Prepare the research report both written and


for oral presentation using effective
communication skills. (CILO6)

4. Hypothesis Testing of Continuous Data for more


than Two Sample Groups

Apply the ethical standards of research in


doing the Biostatistics paper (CILO5)

5. Hypothesis Testing for Categorical Data: One,


Two, and three or more groups

Note Taking
Journals
Brainstorming groups
Research Paper
Chat room sessions
Student Presentations
Research Presentation.
Poster presentation

6. Correlation (Pearsons, Spearmans, PhiCoefficient, and Point-Biserial), Regression,


Agreement/Concordance.
5

GRADING SYSTEM
Lecture Grade = 80%
Class Standing
Quizzes
Activities
Examination
Semestral Grade = Average of the 3 grading
period grades X 0.8 +20(Research)

50%

50%

Research Report (Written and Oral) = 20%


Parts of the research report:
Introduction
Statement of the Problem and Hypotheses
Review of Related Literature
Method and Sampling Technique
Discussion of Results (include Statistical Tests)
Conclusion and Recommendations
Culminating Activity:
Paper Presentation to a Panel of Evaluators

Note: Passing cut off (raw score) - 60%


RECOMMENDED TEXTBOOK:
Kellar, Stacey Plichta (2013), Munros Statistical Methods for Health Care Research, Wolters Luwer Health/ Lippincott Williams & Wilkins.
REFERENCES:
Brase, Charles (2006), Understanding basic statistics. Boston, MA: Houghton Mifflin Co.
Bryant, Patrick J. and Pace, Heather A. (2009), Evidence Based Medicine for Clinical Decision Making. ASHSP.
Dawson, Beth and Trapp, Robert (2004), Basic & Clinical Biostatistics, 4th edition, McGraw-Hill Education(Asia)
Rosner, Bernard (2012). Biostatistics, Cenage Learning Asia Pte.Ltd.

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