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mangostana).
Abstract
Many tropical plants have interesting biological activities with potential therapeutic applications.
Garcinia mangostana Linn. (GML) belongs to the family of Guttiferae and is named "the queen
of fruits". It is cultivated in the tropical rainforest of some Southeast Asian nations like
Indonesia, Malaysia, Sri Lanka, Philippines, and Thailand. People in these countries have used
the pericarp (peel, rind, hull or ripe) of GML as a traditional medicine for the treatment of
abdominal pain, diarrhea, dysentery, infected wound, suppuration, and chronic ulcer.
Experimental studies have demonstrated that extracts of GML have antioxidant, antitumoral,
antiallergic, anti-inflammatory, antibacterial, and antiviral activities. The pericarp of GML is a
source of xanthones and other bioactive substances. Prenylated xanthones isolated from GML
have been extensively studied; some members of these compounds possess antioxidant,
antitumoral, antiallergic, anti-inflammatory, antibacterial, antifungal and antiviral properties.
Xanthones have been isolated from pericarp, whole fruit, heartwood, and leaves. The most
studied xanthones are alpha-, beta-, and gamma-mangostins, garcinone E, 8-deoxygartanin, and
gartanin. The aim of this review is to summarize findings of beneficial properties of GML's
extracts and xanthones isolated from this plant so far.
Xanthones in Mangosteen
Our immune system tries to keep trillions of cells in our bodies protected from disease-causing toxins, free radicals,
viruses, bacteria, fungi and other harmful agents.
At times, though, our immune system gets overwhelmed. Our bodies get sick, often because of free radical
damage.
A free radical is an unstable atom with an unpaired electron. When a free radical comes in contact with a stable
atom, it steals the electron it needs from the stable atom. This leaves the once stable atom irreparably damaged
and prone to succumb to disease.
Antioxidants counteract free radicals. They have an extra electron that they can share with free radicals. Because
of this ability, they are able to prevent free radicals from attacking healthy atoms or cells.
Mangosteen contains powerful antioxidants and immune system boosters called Xanthones, natural chemical
compounds which were proven to possess a variety of potent medicinal properties.
Xanthones occupy a special place in the Mangosteen's arsenal of healing compounds. They have been shown to
have more potent antioxidant activity than vitamin E, one of nature's most powerful known antioxidants.
A laboratory test known as ORAC (Oxygen Radical Absorbance Capacity), for example, showed that an ounce of
Mangosteen juice provides 20 to 30 times more capacity to absorb free radicals than an ounce of most fruits and
vegetables.
See also:
* Health Journal: Feeding the Mind for a Healthier Tomorrow, Volume 44, Number 2, 2004; Mediavision, LLC; www.mangosteentools.com.
** Mangosteen: Super Nutrition for the 21st Century, A Holistic Approach; Roland F. Phillips, Jr., B.A., B.S., D.C.; www.mangosteentools.com
*** Wellness Report: Feeding the Mind for a Healthier Tomorrow, Volume 52, Number 1, 2004; MediaVision, LLC; www.mangosteentools.com.
**** Health Journal: Feeding the Mind for a Healthier Tomorrow, Volume 44, Number 2, 2004; MediaVision, LLC; www.mangosteentools.com.