Professional Documents
Culture Documents
Nucleic Acids
Polynucleotides whose primary structure
contains a code or set of directions by which
they can duplicate themselves and guide the
synthesis of proteins.
2 types of nucleic acids:
1. DNA found mainly in the nucleus, contains
genetic codes to make RNA
2. RNA found in the cytoplasm although
synthesized in the nucleus, contains codes to
make proteins
SUGAR
Ribose or
Deoxyribose
BASE
PURINES
PYRIMIDINES
NUCLEOTIDE
RIBOSE
CH2OH
C
H
OH
OH
CH2OH
OH
C
H
OH
OH
Some unusual
nucleobases (found
principally in tRNA)
Purine Nucleotides
Purine Nucleotides
Pyrimidine Nucleotides
Pyrimidine Nucleotides
Pyrimidine Nucleotides
Supercoiling in
Prokaryotes
Supercoiling in
Prokaryotes
Supercoiling in
Eukaryotes
Denaturation of DNA
Involves breaking of H-bonds between base
pairs and the disruption of stacking
interactions.
Usually carried out by heating the DNA in
solution.
Greater amount of G-C pairs, higher melting
temperature of a DNA molecule.
G-C pairs are also more hydrophobic, so they
stack better, so higher melting temp.