ACKNOWLEDGEMENT

This project has been presented after a series of

references, investigations and motivations of my
teachers, friends and well-wishers.
This project stands firm over the rigid support and
guidance of my respected teachers from the Dept. of
Chemistry. I would have never been able to
complete this project successfully if I was not guided
by Mrs. Ruma Saha & Mrs. Atreyi Chatterjee.
Hope it will live to the expectations of my teachers.

CERTIFICATE

This is to certify that Sri Arnab Chakrabarti having

Board Roll no: _________ a student of class XII(Sc)
of Sudhir Memorial Institute, has successfully
completed the project entitled
A Comparative study of Antacid Tablets under my
supervision and guidance.

Date: ______________.

Internal Examiner

External Examiner

DECLARATION

I,Sri Arnab Chakrabarti, bearing Roll no:_______

hereby declare that the project entitled
A Comparative study of Commercial Antacids
has been submitted by me to the Dept. of Chemistry,
Sudhir Memorial Institute for the fulfillment of
AISSCE
2014-2015
Chemistry
Practical
Examination, CBSE, New Delhi.

_______________________
_
.(Signature of Candidate)

INDEX

SL. No.
1.

Topic
Experiment & Requirements.

2.

Procedure.

3.

Observation.

4.

Analysis of Antacid Tablet.

5.

Conclusion.

6.

Bibliography.

COMPARATIVE STUDY OF
COMMERCIAL ANATCIDS.
EXPERIMENT
To analyse the given sample of commercial
antacid by determining the amount of
Hydrochloric Acid(HCl) it can neutralize.

REQUIREMENTS
Burettes, pipettes, titration flask, conical
flask, beaker, weight box, fractional weight,
NaOH(Sodium Hydroxide), Na2CO3(Sodium
Carbonate), HCl(Hydrochloric acid) and
phenolphthalein.

PROCEDURE
1 litre of approximately N/10 HCl solution
was prepared by diluting 10 mL of the
concentrated acid to 1 litre.
Similarly, 1 litre of approximately N/10
NaOH solution was made by dissolving 4.0
g of NaOH to prepare 1 litre of solution.
N/10 Na2CO3 solution was prepared by
weighing exactly 1.325 g of anhydrous
sodium carbonate and then dissolving it in
water to prepare exactly 0.25 litre(250
mL) of solution.
The HCl solution was standardized by
titrating it against the standard Na2CO3
solution using methyl orange as indicator.
Similarly, NaOH solution was
standardized by titrating it against

standardized HCl solution using

phenolphthalein as indicator.
The various samples of antacid tablets
were powdered and weighed 1.0 g of each.
A specific volume of standardized HCl
was added to each of the weighed
samples taken in conical flasks. The acid
was added in slight excess, so that it can
neutralize all the alkaline components of
the tablet.
2 drops of phenolphthalein was added and
the flask was warmed till most of powder
dissolved. Insoluble material were
filtered off.
The solution was titrated against the
standardized NaOH solution, till a
permanent pinkish tinge was obtained.

OBSERVATION AND CALCULATION

Standardisation of HCl solution:
Volume of N/10 Na2CO3 solution taken= 25mL
SL. No.
1.
2.
3.

Burette Reading
Initial(mL)
0
0
0

Final(mL)
10.6
10.5
10.6

Concordant Reading = 10.6 mL.

Applying Normality equation,
N1V1 = N2V2.
N1 x 10.6 = 1/10 x 25
Normality of HCl, N1 = 0.23.

Vol of acid
used (mL)
10.6
10.5
10.6

Standardisation of NaOH solution:

Volume of the given NaOH solution taken =
20mL.
SL. No.
1.
2.
3.

Burette Reading
Initial(mL)
0
0
0

Final(mL)
19.6
19.5
19.6

Concordant Reading = 19.6 mL.

Applying Normality equation,

N1V1 = N2V2.
N1 x 19.6 = 1/10 x 25
Normality of NaOH, N1 = 0.12.

Vol of base
used (mL)
19.6
19.5
19.6

ANALYSIS OF ANTACID TABLETS

Weight of antacid tablet powder= 1.0 g.
Weight of HCl solution added= 50 g.
SL. No.

1.
2.
3.

Antacid

Gelusil
Digene
Divole

Vol of

Vol of

NaOHsoln

HClsoln for

for

neutralizing

neutralizing

1.0 g of

ususedHCl

antacid

(mL)
0.3
28.1
46.5

matter(mL)
49.7
21.9
3.5

CONCLUSION
The antacid for which maximum volume of
HCl is used for neutralizing, is most
effective.

BIBLIOGRAPHY
Internet sources:
1. http://www.google.com
2. http://www.wikipedia.org
3. http://www.meritnation.com

Books:
1. Comprehensive Practical Chemistry.
2. Chemistry (NCERT).
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