Exam 1 - F13

CH 369 Exam 1
September 24 2013
Name: __________________________________________ eID ________________
Helpful Equations:
degrees K = 273 + C
Section I (32 points): 1 point each

1. In humans, approximately _____ % of the genome encodes proteins.
A) 78
B) 45
C) 33
D) 11
E) 1.5
2. The similarity of one organism to another (for example a bacteria versus a human) is most easily done by
comparing which biopolymer?

A) nucleic acids
B) polysaccharides
C) proteins
D) lipids
E) all of the above
3. During the initial synthesis of collagen molecules, _____ and _____ are most often incorporated into the
growing protein.
A) Ser; Gly
B) Pro; Ala
C) Gly; Pro
D) Ala; Gly
E) Ser; Pro
4. A base found exclusively in DNA is _____ while _____ is found only in RNA.
A) adenine; cytosine
D) cytosine; guanine
B) guanine; thymine
E) thymine; uracil
C) uracil; adenine
5. The purines found in nucleic acids are _____ and _____.
D) adenine; guanine
B) guanine; thymine
E) thymine; uracil
C) uracil; adenine
6. What is the N-terminal residue of the peptide AYSDG?
A) glutamic acid
D) alanine
B) glycine
E) none of these choices
C) aspartic acid
7. When a non-polar substance is added to water, how do the molecules of water behave?
A) the regular hydrogen bond pattern is disrupted resulting in a decrease of entropy
B) the regular hydrogen bond pattern is disrupted resulting in an increase of entropy
C) the regular hydrogen bond pattern is disrupted resulting in a decrease of enthalpy
D) the regular hydrogen bond pattern is disrupted resulting in an increase of enthalpy
E) none of the above
Scrambled version A
Page 1
8. What type of bond is made between nucleotides?

A) ester
B) phosphate ester
C) phosphodiester
D) glycosidic
9. A technique for determining protein structure that requires crystals of the protein is ___.
A) NMR spectroscopy
D) mass spectrometry
B) X-ray crystallography
C) electron crystallography
10. Each kinesin head contains a binding site for _____ and a binding site for _____.
A) tubulin; GTP
D) actin; ATP
B) another kinesin molecule; GTP
E) tubulin; ATP
C) myosin; ATP
11. What is the most prevalent secondary structure observed in the proteins of intermediate filaments?
A) -helices
D) -sheets
B) -helices
E) both -helices and -helices are observed
C) -sheets
12. The formation of a dipeptide from two amino acids requires ___.
A) reduction of the -carboxyl group
D) loss of water
B) protonation of the -amine group
C) interaction of the two side-chains
13. The 5 end of a polynucleotide contains _____ while the 3 end contains _____.
A) a hydroxyl group; a phosphate group
D) a hydroxyl group; a hydroxyl group
B) a phosphate group; a hydroxyl group
C) a phosphate group; a phosphate group
14. Fatty acid anions most commonly assemble into _____ in aqueous solution.
A) lipid bilayers
D) liposomes
B) solvent-filled vesicles
C) micelles
15. Disulfide bonds form between two residues of which amino acid?
A) Met
B) Ser
C) Asn
D) Thr
E) Cys
16. Which of the following is a physical property of water that results from hydrogen bonding?
A) high boiling point relative to molecular weight
B) a solid state that is less dense than the liquid state
C) high surface tension
D) ability to solubilize polar molecules
E) all of the above
Scrambled version A
Page 2
17. What level of protein structure is characterized by the amino acid sequence?
A) primary
D) quaternary
B) secondary
C) tertiary
18. What is the prominent type of secondary structure observed in myoglobin?
A) -helices
D) antiparallel -sheets
B) -bends
E) -helices
C) parallel -sheets
19. Which amino acid is critical for crosslinking of collagen trimers?
A) Ser
B) Lys
C) His
D) Cys
20. Entropy is used to measure _____.
A) free energy
B) heat content
C) temperature
E) Gln
D) randomness
E) all of the above
21. The predominant non-covalent interaction seen in -helices and -sheets is ___.
A) electrostatic interactions
D) hydrophobic interactions
B) hydrogen bonds
E) all of these choices
C) dipole-dipole interactions
22. Due to the formation of hydrogen bonds, _____ is highly soluble in water.
A) carbon dioxide
D) octane
B) sodium chloride
E) cholesterol
C) methanol
23. Which of the following molecules would be prevented from readily crossing a lipid bilayer?
A) glucose
D) water
B) sodium ions
E) all of the above
C) potassium ions
24. The most common base pairs in DNA are _____ and _____.
A) A-T; A-G
B) G-C; C-A
C) T-A; A-U
D) C-G; T-A
E) G-U; A-T
25. The individual hemoglobin subunits and myoglobin share similar _____ structure but have rather different
_____ structure.
A) primary; secondary
B) secondary; tertiary
C) primary; tertiary
D) secondary and tertiary; primary

E) primary and secondary; tertiary
26. The central ion of the heme group of hemoglobin is _____.

A) Cu+
D) Fe3+
B) Cu2+
C)
Fe2+
Scrambled version A
Page 3
27. An A-T base pair consists of _____ H-bond(s); a C-G base pair consists of _____ H-bond(s).
A) 1; 2
B) 2; 1
C) 2; 2
D) 3; 2
E) 2; 3
28. Which of the following is an example of a conservative amino acid substitution?
A) Ile Leu
B) Ser Glu
C) Phe Tyr
D) Asp Gln
E) Arg Cys
29. Molecular chaperones assist proteins in the formation of ___.

A) aggregates
D) primary structure
B) tertiary structure
C) peptide bonds
30. The strongest non-covalent interactions are _____.
A) van der Waals interactions
B) London dispersion forces
C) hydrogen bonds
D) dipole-dipole interactions
E) ionic interactions
31. Based upon its side chain, how is the amino acid Ser classified?
A) non-polar
D) negatively charged
B) polar
C) positively charged
32. What functional groups are present in the following molecule?
A) amine and carboxylic acid

B) amine, ketone and carboxylic acid
C) amine, amide and carboxylic acid
D) alcohol, amine, amide and carboxylic acid

E) none of the above are correct
Section II (50 points): 2 points each

33. If the following mixture of proteins was applied to a size-exclusion chromatography column, what would
be the order of elution? (A Da or Dalton is in units of g/mol.)

Proteins with molecular weights: myoglobin (17.7 kDa) , hemoglobin (64.5 kDa) , lysozyme (14.3 kDa)
and triose phosphate isomerase (57.4 kDa)
A) lysozyme, myoglobin, triose phosphate isomerase, hemoglobin
B) triose phosphate isomerase, hemoglobin, lysozyme, myoglobin
C) hemoglobin, myoglobin, lysozyme, triose phosphate isomerase
D) hemoglobin, triose phosphate isomerase, myoglobin, lysozyme,
E) cannot be determined
Scrambled version A
Page 4
34. The helical structure of collagen contains _____.

A) three right-handed helices wound around each other in a right-handed triple helix
B) three right-handed helices wound around each other in a left-handed triple helix
C) three left-handed helices wound around each other in a left-handed triple helix
D) three left-handed helices wound around each other in a right-handed triple helix
35. If a protein underwent a mutation such that a Glu residue was changed to another amino acid, which of the
following amino acids would least likely result in a change in the overall structure of the protein?
A) Ser
B) Asp
C) Gln
D) Lys
E) Ala
36. If a reaction at 37C has a H of 23 kJ/mol and a S of 337 J/Kmol, what is the G for the reaction?
A) 65 kJ/mol
D) -19 kJ/mol
B) -42 kJ/mol
C) 18 kJ/mol
37. Which of the following structures shows the prevalent form of histidine at pH 5?
A) a
B) b
C) c
D) d
38. The following is an example of ___.
A) parallel -helix
B) parallel -sheet
C) antiparallel -helix
D) antiparallel -sheet
Scrambled version A
Page 5
39. What is the pH of a solution that contains three parts of acetic acid and one part sodium acetate? The pK
for acetic acid is 4.76.

A) 5.24
B) 5.06
C) 4.46
D) 4.28
E) cannot be determined from the given information
40. When oxygen is bound to the heme group of myoglobin, it is coordinated between _____ and _____.
A) F8 His; Fe3+ of heme
D) E7 His; Fe2+ of heme
B) E7 His; Fe3+ of heme
C) F8 His;
Fe2+ of heme
41. The side chain of serine could interact with the side chain of ___ using a(n) ___.
A) Val; hydrophobic interaction
D) Asn; electrostatic interaction
B) His; hydrogen bond
C) Gln; hydrophobic interaction
42. An open reading frame is defined by _____.
A) a start and stop codon
B) homology with other species
C) placement on a genome map
D) presence of transposable elements

E) absence of highly repetitive sequences
43. Which of the following is a characteristic of Chargaff's rules?

A) A + T = C + G
B) A + G = C + T
C) A + G = C + U
D) all organisms have identical amounts of all four nucleotides
44. Which of the following explains the conversion of hemoglobin subunits from deoxy to oxy state?
A) all four subunits switch simultaneously
B) each subunit switches only upon oxygen binding to the particular subunit
C) both subunits simultaneously switch first followed by both subunits
D) both subunits simultaneously switch first followed by both subunits
45. Which of the following biopolymers is correctly paired with the bond that forms between the monomers?
A) protein: ester bond
D) RNA: phosphate bond
B) polysaccharide: glycosidic bond
E) all of the above
C) DNA: phosphate bond
46. Which of the following non-covalent interactions is the most important in maintaining the structure of the
double helix?
A) phosphodiester bonds
B) hydrogen bonds
C) London dispersion forces
D) van der Waals interactions

Scrambled version A
Page 6
47. Which of the following functional groups has two hydrogen bond donors and one hydrogen bond acceptor?
A) alcohol
D) amine
B) ester
E) amide (N atom only)
C) thiol
48. Considering the energetics of transferring nonpolar molecules from water to a nonpolar solvent, the factor
TS is generally _____, causing G to be _____.

A) positive; negative
B) negative; negative
C) positive; positive
D) negligible; either positive or negative
49. In the following figure, which bond would be unable to rotate?
A) a
B) b
C) c
D) d
50. Which of the following occurs in hemoglobin upon oxygen binding?

A) the heme Fe2+ is pulled out of the plane of the heme group
B)
C)
D)
E)
the His coordinated to the heme Fe2+ is pushed away from the heme group
the central cavity between the four subunits is decreased in size
hemoglobin changes from the R state to the T state
all of the above occur
51. How does CO2 affect hemoglobin-oxygen binding?

A) CO2 binds directly to the oxygen binding site, displacing oxygen and thus promoting the deoxy state
B) CO2 displaces BPG, thus promoting the oxy state
C) CO2 is converted to bicarbonate and H+ which promotes the oxy state
D) CO2 is converted to bicarbonate and H+ which promotes the deoxy state
52. At a pH above its pKa, the -amino group of lysine is ___.
A) protonated and neutral
D) deprotonated and negatively charged
B) protonated and positively charged
C) deprotonated and neutral
Scrambled version A
Page 7
53. Differences in structure between a DNA helix and an RNA helix can predominantly be attributed to the
presence of _____ in RNA.

A) uracil
B) 2 hydroxyl group
C) 3 hydroxyl group
D) smaller sizes of RNA molecules

54. If the pK values for phosphoric acid are 2.15, 6.82 and 12.38, at what pH would one observe equal
amounts of H2 PO4 - and HPO4 2-?

A) 2.15
B) 4.49
C) 6.82
D) 9.60
E) 12.38
55. What would be the resulting pH if one ml of 1.0 M NaOH was added to one liter of pure water (assume
pH 7.0)?
A) 1
B) 3
C) 7.3
D) 11
E) 13
56. In an aqueous solution, if the [OH-] is 3.010-5 M, what is the [H+]?

A) 7.010-9
D) 3.310-10
B) 7.010-2
C)
3.310-3
57. Which of the following amino acids has a positively charged side chain at pH 7.4?
A) Glu
B) Ala
C) Lys
D) Leu
E) His
Section III (18 points): 3 points each

58. You have a short piece of synthetic RNA that you want ot use as a probe to identify a gene in a sample of
DNA. The RNA probe has a tendency to hybridize (form base pairs) with sequences that are only weakly
complementary. Should you increase or decrease the temperature to improve your chances of tagging
(binding) the correct sequence?
A) Increase temperature
B) Decrease temperature
59. Considering a 0.1 M formic acid buffer, what is the concentration of formic acid present in a solution of pH
4.25 if the pK of formic acid is 3.75?

A) 0.024 M
B) 0.033 M
C) 0.067 M
D) 0.076 M
60. Which one of the three structures below would not exist at ANY pH?
A)
B)
C)
61. Highly active muscle generates lactic acid by respiration so fast that the blood passing through the muscle
actually experiences a drop in pH from about 7.4 to about 7.2. Under these conditions, would hemoglobin
release more or less O2 than it does at pH 7.4?
A) Will release more O2
B) Will release less O2
Scrambled version A
Page 8
62. For the reaction in which reactant A is converted to product B, tell whether this process is favorable at (i)
4o C and (ii) 37o C.
A) The reaction is favorable at both temperatures.

B) The reaction is favoarable at 4o C but not at 37o C.
C) The reaction is favorable at 37o C but not at 4o C.
D) The reaction is unfavorable at both temperatures.
63. You have a mixture of 3 proteins, listed in the table below with their relevant properties. You are
interested in isolating aspartate transaminase using ion exchange chromatography with DEAE resin. Given
the values in the table below: 1) what pH would you use in order to ensure that aspartate transaminase
protein binds to the column and that the others do not? Assume that your efforts are successful -- 2) how
will you elute aspartate transaminase from the column? Choose the correct conditions from the list below.
Protein
Aspartate transcarbamylase
Myoglobin
Aspartate transaminase
pI
9.8
7.0
5.0
A) 1) Initial pH = 10.0; 2) lower pH to 6

B) 1) Initial pH = 8; 2) raise pH to 10
C) 1) Initial pH = 4; 2) raise pH to 5 or higher
D) 1) Initial pH = 6; 2) lower pH to 5 or less

E) 1) Initial pH = 8; 2) lower pH to 7
Scrambled version A
Page 9
Answer Key - Exam1_F13

1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
E
A
C
E
D
D
A
C
B
E
A
D
B
C
E
E
A
E
B
D
B
C
E
D
D
C
E
A
B
E
B
C
D
D
B
E
C
D
D
D
B
A
B
A
B
D
D
A
B
C
D
C
B
C
D
D
Scrambled version A
Page 10
57.
58.
59.
60.
61.
62.
63.
C
A
A
B
A
C
D
Scrambled version A
Page 11
CH 369 Exam 1
September 24 2013
Name: __________________________________________ eID ________________
Helpful Equations:
degrees K = 273 + C

B) guanine; thymine
E) thymine; uracil
C) uracil; adenine
A) Ser
B) Lys
C) His
D) Cys
E) Gln


growing protein.
A) Ser; Gly
B) Pro; Ala
C) Gly; Pro
D) Ala; Gly

A) Met
B) Ser
C) Asn
D) Thr
D) adenine; guanine
B) guanine; thymine
E) thymine; uracil
C) uracil; adenine
A) aggregates
C) peptide bonds
Scrambled version B
Page 1
E) Ser; Pro
E) Cys
A) non-polar
B) polar
_____ structure.

A) -helices
D) -sheets
B) -helices
C) -sheets
A) lipid bilayers
D) liposomes
C) micelles
C) hydrogen bonds
A) A-T; A-G
B) G-C; C-A
C) T-A; A-U
D) C-G; T-A
E) G-U; A-T
E) all of the above
A) Cu+
D) Fe3+
B) Cu2+
C)
Fe2+
Scrambled version B
Page 2

A) nucleic acids
B) polysaccharides
C) proteins
D) lipids
E) all of the above
A) NMR spectroscopy
A) glutamic acid
D) alanine
B) glycine
C) aspartic acid
A) tubulin; GTP
D) actin; ATP
E) tubulin; ATP
C) myosin; ATP
A) 78
B) 45
C) 33
D) 11
E) 1.5
A) primary
D) quaternary
B) secondary
C) tertiary
A) glucose
D) water
B) sodium ions
E) all of the above
C) potassium ions
A) 1; 2
B) 2; 1
C) 2; 2
D) 3; 2
E) 2; 3
A) carbon dioxide
D) octane
B) sodium chloride
E) cholesterol
C) methanol
Scrambled version B
Page 3

A) free energy
B) heat content
C) temperature
D) randomness
E) all of the above

A) ester
B) phosphate ester
C) phosphodiester
D) glycosidic
B) hydrogen bonds
D) loss of water
A) -helices
B) -bends
E) -helices
C) parallel -sheets
A) Ile Leu
B) Ser Glu
C) Phe Tyr
D) Asp Gln
E) Arg Cys



A) 5.24
B) 5.06
C) 4.46
D) 4.28

A) 2.15
B) 4.49
C) 6.82
Scrambled version B
D) 9.60
Page 4
E) 12.38
A) 65 kJ/mol
D) -19 kJ/mol
B) -42 kJ/mol
C) 18 kJ/mol
A) a
B) b
C) c
D) d
A) 7.010-9
D) 3.310-10
B) 7.010-2
C)
3.310-3
double helix?
B) hydrogen bonds

C) F8 His;
Fe2+ of heme
Scrambled version B
Page 5
A) a
B) b
C) c
D) d

B)
C)
D)
E)

A) Glu
B) Ala
C) Lys
D) Leu
Scrambled version B
Page 6
E) His

A) parallel -helix
B) parallel -sheet
pH 7.0)?
A) 1
B) 3
C) 7.3

D) 11
E) 13



A) uracil
B) 2 hydroxyl group
C) 3 hydroxyl group

A) alcohol
D) amine
B) ester
C) thiol
Scrambled version B
Page 7
E) all of the above
A) A + T = C + G
B) A + G = C + T
C) A + G = C + U
A) Ser
B) Asp
C) Gln
D) Lys
E) Ala


A) 0.024 M
B) 0.033 M
C) 0.067 M
D) 0.076 M
A)
B)
C)

Scrambled version B
Page 8
Protein
Myoglobin
pI
9.8
7.0
5.0


Scrambled version B
Page 9

1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
E
B
C
C
E
D
B
B
B
D
A
C
E
D
E
C
A
A
B
D
E
E
A
E
E
C
D
C
B
D
E
A
C
D
C
E
C
B
D
D
D
B
C
A
D
D
C
A
D
D
A
D
B
D
B
B
Scrambled version B
Page 10
57.
58.
59.
60.
61.
62.
63.
B
A
A
B
C
D
A
Scrambled version B
Page 11
CH 369 Exam 1
September 24 2013
Name: __________________________________________ eID ________________
Helpful Equations:
degrees K = 273 + C

A) -helices
D) -sheets
B) -helices
C) -sheets



A) ester
B) phosphate ester
C) phosphodiester
D) glycosidic

C) hydrogen bonds

A) Ser
B) Lys
C) His
D) Cys
D) loss of water
Scrambled version C
Page 1
E) Gln

A) -helices
B) -bends
E) -helices
C) parallel -sheets
A) non-polar
B) polar
A) tubulin; GTP
D) actin; ATP
E) tubulin; ATP
C) myosin; ATP
A) primary
D) quaternary
B) secondary
C) tertiary
A) NMR spectroscopy
A) 1; 2
B) 2; 1
C) 2; 2
D) 3; 2
E) 2; 3
A) Met
B) Ser
C) Asn
D) Thr
E) Cys
B) hydrogen bonds
A) Ile Leu
B) Ser Glu
C) Phe Tyr
D) Asp Gln
A) carbon dioxide
D) octane
B) sodium chloride
E) cholesterol
C) methanol
Scrambled version C
Page 2
E) Arg Cys

A) 78
B) 45
C) 33
D) 11
E) 1.5
A) lipid bilayers
D) liposomes
C) micelles
A) glucose
D) water
B) sodium ions
E) all of the above
C) potassium ions
A) aggregates
C) peptide bonds
growing protein.
A) Ser; Gly
B) Pro; Ala
C) Gly; Pro
D) Ala; Gly
E) Ser; Pro
E) all of the above
B) guanine; thymine
E) thymine; uracil
C) uracil; adenine
_____ structure.

Scrambled version C
Page 3

A) nucleic acids
B) polysaccharides
C) proteins
D) lipids
E) all of the above
A) A-T; A-G
B) G-C; C-A
C) T-A; A-U
A) free energy
B) heat content
C) temperature
D) C-G; T-A
D) randomness
E) all of the above

A) Cu+
D) Fe3+
B) Cu2+
C)
Fe2+

A) glutamic acid
D) alanine
B) glycine
C) aspartic acid
D) adenine; guanine
B) guanine; thymine
E) thymine; uracil
C) uracil; adenine

A) parallel -helix
B) parallel -sheet
Scrambled version C
Page 4
E) G-U; A-T
pH 7.0)?
A) 1
B) 3
C) 7.3
D) 11
E) 13


A) alcohol
D) amine
B) ester
C) thiol
A) Glu
B) Ala
C) Lys
D) Leu
E) His

A) 5.24
B) 5.06
C) 4.46
D) 4.28
double helix?
B) hydrogen bonds

E) all of the above
Scrambled version C
Page 5
A) a
B) b
C) c
D) d
A) a
B) b
C) c
D) d
A) 65 kJ/mol
D) -19 kJ/mol
B) -42 kJ/mol
C) 18 kJ/mol
Scrambled version C
Page 6

B)
C)
D)
E)

A) 2.15
B) 4.49
C) 6.82
D) 9.60
E) 12.38
A) Ser
B) Asp
C) Gln
D) Lys
E) Ala

A) uracil
B) 2 hydroxyl group
C) 3 hydroxyl group




A) 7.010-9
D) 3.310-10
B) 7.010-2
C) 3.310-3
A) A + T = C + G
B) A + G = C + T
C) A + G = C + U
Scrambled version C
Page 7

C) F8 His;
Fe2+ of heme

Protein
Myoglobin
pI
9.8
7.0
5.0



A) 0.024 M
B) 0.033 M
C) 0.067 M
D) 0.076 M
Scrambled version C
Page 8

A)
B)
Scrambled version C
C)
Page 9

1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
A
C
C
E
B
D
E
B
E
A
B
E
E
B
B
A
C
E
C
E
B
C
E
E
D
A
A
D
D
C
D
D
D
D
A
D
D
C
D
D
B
C
B
E
D
D
C
B
C
B
B
A
D
B
C
D
Scrambled version C
Page 10
57.
58.
59.
60.
61.
62.
63.
A
D
A
A
C
A
B
Scrambled version C
Page 11

Exam 1 - F13

Uploaded by

Document Information

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Exam 1 - F13

Uploaded by

Copyright:

Available Formats

CH 369 Exam 1

Section I (32 points): 1 point each

comparing which biopolymer?

8. What type of bond is made between nucleotides?

D) secondary and tertiary; primary

26. The central ion of the heme group of hemoglobin is _____.

E) none of the above

29. Molecular chaperones assist proteins in the formation of ___.

A) amine and carboxylic acid

D) alcohol, amine, amide and carboxylic acid

Section II (50 points): 2 points each

be the order of elution? (A Da or Dalton is in units of g/mol.)

34. The helical structure of collagen contains _____.

38. The following is an example of ___.

for acetic acid is 4.76.

D) E7 His; Fe2+ of heme

B) E7 His; Fe3+ of heme

E) none of the above

D) presence of transposable elements

43. Which of the following is a characteristic of Chargaff's rules?

D) van der Waals interactions

TS is generally _____, causing G to be _____.

49. In the following figure, which bond would be unable to rotate?

50. Which of the following occurs in hemoglobin upon oxygen binding?

51. How does CO2 affect hemoglobin-oxygen binding?

presence of _____ in RNA.

D) smaller sizes of RNA molecules

amounts of H2 PO4 - and HPO4 2-?

56. In an aqueous solution, if the [OH-] is 3.010-5 M, what is the [H+]?

E) none of the above

Section III (18 points): 3 points each

4.25 if the pK of formic acid is 3.75?

4o C and (ii) 37o C.

A) The reaction is favorable at both temperatures.

A) 1) Initial pH = 10.0; 2) lower pH to 6

D) 1) Initial pH = 6; 2) lower pH to 5 or less

Answer Key - Exam1_F13

Section I (32 points): 1 point each

3. What functional groups are present in the following molecule?

A) amine and carboxylic acid

D) alcohol, amine, amide and carboxylic acid

5. Disulfide bonds form between two residues of which amino acid?

D) secondary and tertiary; primary

E) none of the above

comparing which biopolymer?

27. Entropy is used to measure _____.

28. What type of bond is made between nucleotides?

Section II (50 points): 2 points each

D) deprotonated and negatively charged

for acetic acid is 4.76.

amounts of H2 PO4 - and HPO4 2-?

E) none of the above

D) van der Waals interactions

D) E7 His; Fe2+ of heme

B) E7 His; Fe3+ of heme

E) none of the above

42. In the following figure, which bond would be unable to rotate?

43. Which of the following occurs in hemoglobin upon oxygen binding?

be the order of elution? (A Da or Dalton is in units of g/mol.)

TS is generally _____, causing G to be _____.

49. The following is an example of ___.

51. An open reading frame is defined by _____.

D) presence of transposable elements

TS is generally _, causing G to be _.

TS is generally _, causing G to be _.

TS is generally _, causing G to be _.