Professional Documents
Culture Documents
O RIGINAL A RTICLES
A survey of medicinal plants in two areas of Dinajpur district, Bangladesh including
plants which can be used as functional foods
1
4
M d. Harun-Or-Rashid,
863
2005). It has been noted that the original source of many important pharmaceuticals in current use have been
plants used by indigenous people (Balick, 1996), who traditionally has been a rich source of knowledge on
medicinal and edible plants or plant parts. It has been reported that about 64% of the total global population
remains dependent on traditional medicine and medicinal plants for provision of their health-care needs (Cotton,
1996). In recent years traditional medicine has become of interest to both scientists and the general population
for a number of reasons, which include high price of allopathic drugs beyond the reach of the poorer segments
of society in almost every country, lack of access to medical clinics and hospitals by the rural population of
developing countries, the side-effects and toxicities of modern synthetic drugs, and the realization that
phytochemicals present in plants can be effective therapeutic agents by themselves or serve as effective adjunct
therapies to modern drugs.
Along with the progress of human civilization and the accumulation of knowledge, people have become
more concerned with their eating habits. A concept of functional food has taken place, which denotes food
that not only serves to provide nutrition but also can be a source for prevention and cure of various diseases.
In other words, these foods provide health benefits beyond their nutritive values. T his is not totally a novel
concept for even in ancient times people added spices to their dietary items not only to impart color, taste or
flavoring, but also for their health benefits. Functional foods are often also termed food supplements or
nutraceuticals. In recent years, to consider just one country, the functional food market in Taiwan reached
US$ 1.78 billion in 2005 (Sun 2007).
A number of plants or plant products have been demonstrated in scientific studies that they can be
classified as functional foods. These include both medicinal plants and commonly consumed plants or plant
products. To cite a few examples, carotenoids in green peppers (Capsicum annuum, which has been
traditionally consumed in Central and South American countries for thousands of years) has been shown to
demonstrate antimutagenic activity against some nitroarenes (Gonzaez, 1998). It may be noted that green
peppers are also added to a variety of cooked food items and snacks in various regions of the Indian subcontinent. Chickpea, an edible vegetable (Cicer aretinum) is also considered a functional food and intake of
chickpeas has been recommended in humans with altered lipid profile such as type IIa hyperlipoproteinemia
and diabetes (Zulet, 1999). The functional properties of raw and processed pigeon pea, an edible vegetable
(Cajanus cajan) flour has also been reported (Okpala, 2001). Functional foods that have been found to be
potentially beneficial in the prevention and treatment of cardiovascular disorders include soybeans, oats,
psyllium, flaxseed, garlic, tea, grapes and nuts (Hasler, 2000). It has been reported that bitter herbs have been
consumed from ancient times to alleviate various dyspeptic conditions a condition suffered by about 15-30%
of adult population throughout the world (Saller, 2001). Garlic, a commonly used spice contains over 2,000
biologically active substances and is of importance in dietoprophylaxis and dietotherapy (Swiderski, 2007). The
organosulfur compounds present in garlic appear to be good agents for cancer chemoprevention through
multiple mechanisms like carcinogen metabolism modulation, DNA adduct formation inhibition and upregulation of antioxidant defenses and DNA repair systems (Nagini, 2008). The Zingiberaceae family contains
a number of plants whose rhizomes are eaten as vegetable or added to food items as spices. The family
contains commonly known spices like ginger and turmeric. A study conducted in Taiwan found good
antioxidant and antimicrobial activity in a number of Zingiberaceae plants found within the country (Chen,
2008). The Indian traditional medical systems use turmeric for a number of ailments like wounds, rheumatism,
gastrointestinal disorders, helminthiasis and rhinitis. Other spices used in traditional Indian cooking like onions
and ginger has been found to favorably modulate the process of carcinogenesis, while fenugreek seeds has been
reported to reduce blood glucose and lipids and can be used as an adjunct food in diabetes (Krishnaswamy,
2008). Bearberry (Arctostaphylos uva-ursi), garden pea (Pisum sativum), Norway spruce (Picea abies) and
large-leaved lime (Tilia platyphyllos) extracts reportedly demonstrated inhibition of pancreatic lipase and so
can be considered promising sources for developing functional foods to decrease fat absorption (Slanc, 2009).
In Korea, the wild plant Adenophora triphylla is commonly used in food materials and traditional medicine
as an analgesic, anti-inflammatory and antitussive. Leaf extracts of this plant showed notable levels of total
phenolics and flavonoids and demonstrated good anti-oxidant activities. The results suggested that the plant
can serve the function of a food supplement (Kim, 2009). Overall, there is a growing realization about
medicinal plants that quite a number of them can serve as functional foods and so can be utilized both
nutritionally and medicinally.
Bangladesh is a developing country with a majority of rural population, who lack access to modern healthcare or cannot afford the cost of allopathic drugs. A sizeable section of the population is below the poverty
level of US$1 per day. As a result, malnutrition and diseases arising from malnutrition and poor hygienic
conditions of living are prevalent. The primary health care of the rural population and a substantial section of
urban population are provided by traditional medicinal practitioners or Kavirajes, who possess considerable
expertise on medicinal plants. The medicinal plants utilized by the Kavirajes are usually kept secret and so
864
can vary considerably between Kavirajes of various regions or tribes. It was the objective of the present study
to conduct an ethnomedicinal survey among the Kavirajes of different areas in D inajpur district, Bangladesh
to obtain information on medicinal plants used by them for treatment of diverse ailments. A further objective
of the study was to determine which plant or plant part can be used as functional foods. T he criteria for
judging whether a medicinal plant can serve as a functional food were history of long-term edibility without
any side-effects or toxicities, nutritive value of the plant, and whether the plant has been used by the Kavirajes
for considerable lengths of time for treatment of single or multiple ailments. It is expected that such studies
can make the particularly poorer sections of the people more conscious about consuming plants that can serve
as functional foods and so can be effective in providing nutrition and be of preventive as well as curative
values to people who can ill afford the cost of food and medicines.
M aterials and M ethods
2.1. Study area
Dinajpur district is one of the northern-most districts of Bangladesh and falls roughly between 88 o 20 89 20 E and 25 o 10 - 26 o 05 N. The area is bounded by Nilphamari and Rangpur districts to the east, W est
Bengal province of India to the west, Thakurgaon and Panchagarh districts to the north and Joypurhat district
to the south. The Atrai and the Punabhaba rivers are the major rivers flowing through the district. The survey
was conducted in and around the areas of Bhelamoyee and Shalbon in the district.
o
865
M edicinal plants used by Kavirajes of Bhelam oyee and Shalbon areas in D inajpur district, Bangladesh for treatm ent of various
ailm ents.
Botanical nam e
Fam ily
Local nam e
Parts used
Ailm ents treated and dosage
Table 1:
Sl.
N o.
1
Andrographis paniculata
N ees
Acanthaceae
Kalom egh,
Kalam nath,
Leaf, stem
Justicia adhatoda L.
Acanthaceae
Bashok,
D ankuni,
H arbaksho
Leaf
Justicia gendarussa L.
Acanthaceae
Bishjaron
Leaf
Agavaceae
Agunikundu
Leaf
Agavaceae
Takbir m ati
Leaf
Sansevieria roxburghiana
Schultes & Schultes f.
Aerva sanguinolenta (L.) Bl.
Am aranthaceae
Rong-chita
Leaf
Am aranthus spinosus L.
Am aranthaceae
Kata-khora
Root
Crinum asiaticum L.
Am aryllidaceae
alt. Liliaceae
Bon piyaz,
D hako-ali
Leaf, fruit
Am aryllidaceae
Talm uli
alt. H ypoxidaceae
Leaf, root
10
Semecarpus anacardium L.
Anacardiaceae
Bhela
Leaf
11
Apocynaceae
Chatim
Leaf
12
Carissa carandas L.
Apocynaceae
Korom cha
Leaf, fruit
13
Catharanthus roseus
(L.) G.D onn.
Apocynaceae
N oyon tara
Leaf, flower
14
Apocynaceae
Kurchi
Leaf
15
H olarrhena pubescens
Buch.-H am . W all.
Ex G. D on
Nerium indicum M ill.
Apocynaceae
Korobi
Leaf
16
Apocynaceae
Sharpagondha
Leaf, stem
17
Apocynaceae
Leaf, flower
Araceae
Bon korobi,
Bon togor
Takbir gach
Typhonium trilobatum
(L.) Schott
Aristolochia indica L.
Araceae
Cham ghas
Leaf
Aristolochiaceae
Ishwarm ul
Leaf, root
18
19
20
Leaf
866
Asclepiadaceae
Boro akondo
Leaf, stem
22
Asclepiadaceae
Anantam ul
Leaf, root
23
Asparagaceae
alt. Liliaceae
Shotom uli
Leaf, root
24
M ikania cordata
(Burm . f.) B. L. Robinson
Spilanthes acm ella M urr.
Asteraceae/
Com positae
Asteraceae/
Com positae
Assam lota
Leaf, flower
Rakhal-porni,
Roshun shak
Leaf, flower
28
Wedelia chinensis
(O sbeck) M err.
Xanthium indicum J.
Koenig ex Roxb.
O roxylum indicum Vent.
Asteraceae/
Com positae
Asteraceae/
Com positae
Bignoniaceae
H agra,
Ghaghra
Kanai-dingi
Fruit
29
Bixa orellana L.
Bixaceae
Lotkon
Leaf, fruit
30
Bom bacaceae
Shim ul
Leaf, root
31
Cactaceae
M onsha-debi
Leaf
Clusiaceae
alt. Guttiferae
Colchicaceae
alt. Liliaceae
Ashar pata,
N ageshwar
U lot chandal
Leaf, bark
33
O puntia dillenii
(Ker-Gawl) Haw.
M esua nagassarium
(Burm .f.) Kosterm .
G loriosa superba L.
34
Com bretaceae
Arjun
Bark
35
Com bretaceae
Bohera
Leaf, fruit
36
Com bretaceae
H oritoki
Leaf, fruit
37
Convolvulaceae
Bhui-kum ra
Leaf, root
38
Costus speciosus
(Koen.) Sm .
Costaceae alt.
Zingiberaceae
Keu,
Basukoron
Leaf, stem
39
Crassulaceae
Pathorkuchi
Leaf
40
Kalanchoe pinnata
(Lam .) Pers.
Coccinia grandis (L.) Voigt
Cucurbitaceae
Telakucha
Leaf
41
Cyperaceae
N agarm otha
42
D illenia indica L.
D illeniaceae
Am ortishar
Leaf,
stem , root
Leaf, fruit
25
26
27
32
Leaf
867
D ioscoreaceae
Bon-alu, Kulu
Leaf, root,
tuber, upper
part of tuber
44
D ioscorea bulbifera L.
D ioscoreaceae
Shorochm an
Leaf
45
46
D ioscorea pentaphylla L.
Croton tiglium L.
D ioscoreaceae
Euphorbiaceae
Thubri
Jaipal
Leaf, vine
Leaf
47
Euphorbia hirta L.
Euphorbiaceae
D udhi
Leaf, flower
48
49
Bar-dal
Jam al-gota,
Leaf
Fruit, seed
Kendar,
M ajon gach
50
Phyllanthus em blica L.
Euphorbiaceae
Am loki
Leaf,
bark, fruit
51
Phyllanthus niruri L.
Euphorbiaceae
Bhui-am la
Leaf, flower
52
Euphorbiaceae
Verenda,
Leaf, root
Venna
53
Fabaceae
Shet-kanchan
Leaf
54
Butea m onosperm a
(Lam .) Taub.
Fabaceae
Polash
Leaf, gum
55
Caesalpinia bonduc
(L.) Roxb.
Fabaceae
N atai
Leaf, fruit
56
Fabaceae
Arhor
Leaf,
flower, seed
57
Cassia alata L.
Fabaceae
D adhm ordon,
Leaf
D adhm onijol
58
Cassia fistula L.
Fabaceae
Shonalu,
Banor lathi
Leaf, fruit
59
Cassia occidentalis L.
Fabaceae
Boro kalokashunda
Leaf
60
Cassia sophera L.
Fabaceae
Thon-thoni
Leaf
61
Cassia tora L.
Fabaceae
Chakinda
Leaf
62
Fabaceae
Turog-chandal
Leaf
63
M im osa invisa
C. M artius ex C olla
Saraca asoca
(Roxb.) D e W ilde
Flacourtia sepiaria Roxb.
Fabaceae
Shada
lajjaboti
Ashok
Leaf, bark
Flacourtiaceae
Gobura,
Labiatae
Bayuch,
Prem kata,
H elahuta
Ish-langol
Leaf,
fruit,
flower
Leaf
64
65
66
Fabaceae
Leaf
868
Labiatae
Kashta phol,
Cheton kum ar
Leaf,
root, flower
68
O cim um tenuiflorum L.
Labiatae
alt. Lam iaceae
Tulshi
Leaf,
stem , root
69
M entha arvensis L.
Lam iaceae
Pudina
Leaf, stem
70
Lauraceae
Korpur
Leaf, bark
71
Lauraceae
Tejpata
Leaf
72
Cinnam om um zeylanicum
Blum e
Lauraceae
D aruchini
Bark
73
Lauraceae
Pipul-jongi,
Kak-jonga,
Bijla
Leaf, flower
74
Barringtonia racemosa
(L.) Spreng.
Aloe barbadensis M ill.
Lecythidaceae
75
Liliaceae
76
Lygodium flexuosum
(L.) Sw.
Lygodiaceae
77
M alvaceae
78
79
U rena lobata L.
Stephania japonica
(Thunb.) M iers
80
81
82
Kukur m utha,
Kukur shuka,
Bon tam ak
Pith-berela
Root
Fruit
M alvaceae
M enisperm aceae
Bon-okra
Takam uti,
M akondi
Leaf
Leaf,
flower
M enisperm aceae
Guloncho-ban
Leaf, stem
Ficus hispida L.
M im osaceae
alt. Legum inosae
M oraceae
Kak-dum ur
Leaf
83
M oringaceae
Sajna
Leaf, fruit
84
85
M yristicaceae
M yrtaceae
Joiphol
Labanga
86
Syzygium fruticosum
Roxb. DC.
M yrtaceae
Bonjam ,
Kathjam
Fruit
Leaf,
flower,
flower bud
Leaf
87
N ym phaeaceae
Lal shapla,
Shaluk
Tuber
Piperaceae
89
Piper cubeba L.
90
91
869
Leaf
Piperaceae
M achm achunda
Kababchini
Piper longum L.
Piperaceae
Pipul
Leaf, flower
Cymbopogon citratus
(D C.) Stapf
H edyotis corym bosa
(L.) Lam .
Randia dum etorum
(Retz.) Lam .
Clausena heptaphylla
(Roxb.) H ook. f.)
Poaceae
alt. Gram ineae
Rubiaceae
Lem on ghas
Leaf
Khetpapra
Leaf, flower
Rubiaceae
D honkata
Leaf, stem
Rutaceae
Pan-porag
Leaf
95
Santalum album L.
Santalaceae
Shet chandan
Leaf, stem
96
Sapotaceae
Sofeda
Fruit
97
M anilkara zapota
(L.) P. Royen
Scoparia dulcis L.
Scrophulariaceae
Leaf, flower
98
99
D atura m etel L.
Sm ilacaceae
alt. Liliaceae
Solanaceae
Bon-dhone,
Chini-dhonia
Kum ari lota
D hutura
Leaf, flower
100
Solanaceae
Fruit
101
Solanum nigrum L.
Solanaceae
Bon-tepari,
Shod-tepari
Kakm achi
102
Sterculiaceae
U lot-kom bol
Leaf,
root, flower
103
Sterculiaceae
U dal
Leaf
104
Thym elaeaceae
Agor
Leaf, bark
105
Ferula asafoetida L.
U m belliferae
H ing
Leaf,
flower, seed
106
Clerodendrum indicum
(L.) Kuntze.
Clerodendrum viscosum
Vent.
Verbenaceae
alt. Lam iaceae
Verbenaceae
alt. Lam iaceae
Bam onhati
Leaf
Bhati, Foksha
Leaf, fruit
108
Vitex negundo L.
Verbenaceae
N ishinda
109
Cissus quadrangularis L.
Vitaceae
H arjora
Leaf,
root, fruit
Leaf
110
Leea m acrophylla
Roxb. ex H ornem .
Vitaceae
H osti-korno
-polash
Leaf
111
Am om um subulatum Roxb.
Zingiberaceae
Elach
Leaf, seed
92
93
94
107
Leaf, stem
Leaf, stem
Leaf
N ote that bold lettering indicates plants where whole plant or plant parts can serve as
in combination for medicinal purposes. 14 plants had uses of a combination of leaves with flowers, 10 plants
had uses of a combination of leaves with fruits, and 9 plants had combined uses of leaves with roots. Other
plant parts used in combination were leaves with stems, leaves with barks, leaves with gum, fruits with seeds,
and leaves with seeds. In the case of several plants, three plant parts were administered in combination to treat
ailments. These combinations included leaves with stems and roots (Cyperus scariosus), leaves with fruits and
flower (Flacourtia sepiaria), and leaves with roots and fruits (Vitex negundo). In most cases, juice was
extracted from the plant part(s) and taken orally or applied topically. Other modes of oral administration were
870
boiling the plant part in water and drinking the syrup (e.g. Carissa carandas), direct taking of the plant part
(e.g. root of Amaranthus spinosus), taking pills made from dried plant part (e.g. Terminalia arjuna) or cooking
the plant part and taking it as vegetable (e.g. Typhonium trilobatum). Other modes of topical applications also
included application of crushed plant part to affected area (e.g. Justicia adhatoda), mixing powdered plant parts
with mustard oil followed by topical application (e.g. Costus speciosus) or mixing plant part paste with salt
followed by topical application (e.g. Ricinus communis).
3.3. Medical applications
W ith one exception, in all cases, a single plant was used by the Kavirajes to treat one or multiple
ailments. The exception was the use of a combination of Leucas aspera flowers with Ocimum tenuiflorum root
juice for treatment of asthma and respiratory difficulties. Tabernaemontana divaricata did not have any
medicinal use; its leaves and flowers were used as perfumery. Bauhinia acuminata also did not have any direct
medical use; the leaves of this plant were used by Kavirajes as an ingredient or base for good mixing of
Ayurvedic medicines. It is to be noted in this regard that Ayurvedic medicine is one of the oldest form of
traditional medicine practiced in the Indian sub-continent. The practitioners of Ayurvedic medicine are also
known in Bangladesh as Kavirajes. The Kavirajes interviewed in the present survey though practiced what is
generally referred to as folk medicine, which while having certain similarities with Ayurvedic medicine is
quite different in its simplicity and plant choice.
3.4. Plants which can be classified as functional foods
A number of plants were found among the 111 medicinal plants shown in Table 1 in which plant parts
can serve both nutritive and medicinal purposes and so can be classified as functional foods. These plants were
Amomum subulatum, Bixa orellana, Cajanus cajan, Carissa carandas, Cinnamomum tamala, Cinnamomum
zeylanicum, Coccinia grandis, Dillenia indica, Ferula asafoetida, Manilkara zapota, M entha arvensis, Moringa
oleifera, Nymphaea nouchali, Phyllanthus emblica, Spilanthes acmella, Syzygium aromaticum, Terminalia
belerica, and Terminalia chebula. The edible parts of these plants along with the ailments that are treated or
prevented with the edible parts are shown in Table 2. It is to be noted that Table 2 is not confined to the
present survey only but also presents information obtained thus far in our ongoing ethnobotanical surveys
conducted in different regions and among different tribes of Bangladesh.
It can be seen from Table 2, that the eighteen plants listed as food supplements are also in use in other
regions of Bangladesh by K avirajes, albeit to treat different ailments. The ailments for which the plant parts
were used were diverse and ranged from disorders of body organs to parasitic diseases and diseases arising
from bacterial, viral and fungal infections. Two plants appear unique (at least in our ethnobotanical data
collected thus far) in their use by the Kavirajes of Dinajpur district. These plants are Ferula assafoetida and
Mentha arvensis. Although our available data does not indicate the use of Ferula asafoetida and Mentha
arvensis in other regions of Bangladesh (note that gathering of more ethnobotanical data may change this
picture), a related species of Mentha arvensis, namely Mentha spicata was found to be commonly used by
Kavirajes in other regions of the country. W hile Mentha arvensis was used by the Kavirajes of Dinajpur
district for dysentery, indigestion, and stomach pain, uses of whole plant or leaves of Mentha spicata included
treatment for cancer, nerve disorders, bronchitis, anorexia, indigestion, dysentery, stomach pain, vomiting,
diabetes, edema, fever, headache, lack of appetite, stomach and intestinal diseases, helminthiasis, bloating,
typhus, dermatitis, and seizures, and use as an appetizer (data not shown).
Besides curative purposes, the plants indicated as functional foods also can provide nutritive values, and
regular consumption can have a preventive role against a number of ailments or to maintain healthy body
organs. The most notable plants that we observed in this regard were Coccinia grandis (leaves are chewed
every day by diabetic patients to keep blood sugar under control), Phyllanthus emblica, Terminalia belerica
and Terminalia chebula (fruits are consumed to maintain healthy body conditions), and Spilanthes acmella
(leaves and flowers are taken on a regular basis both to prevent and to treat anemia). Plant parts from other
plants like Mentha arvensis, Cinnamomum tamala, Cinnamomum zeylanicum, Syzygium aromaticum, and
Amomum subulatum are added to cooked food items as spices by the general population on an almost daily
basis and can play a preventive role in the occurrence of gastrointestinal disorders, respiratory problems, and
through increasing palatability and flavor of foods make them more digestible and serve to maintain good
health. It is further to be noted in this regard that Mentha arvensis is usually taken after partaking of meat and
fatty items or items highly rich in calories, where digestibility may be of concern.
871
M edicinal plants of D inajpur district indicating plant parts which can be classified as functional foods based on their edibility
and preventive or curative effects of various ailm ents.
Plant nam e
Edible part
Ailm ents for which plant parts are used to provide preventive or curative effects (includes
data from ethnobotanical surveys conducted in other regions of Bangladesh)
Am om um subulatum
Seed
Acne, gout, spasm s, indigestion, cardiac arrhythm ia.
Bixa orellana
Fruit
Cancer, gonorrhea, kidney diseases, m alaria, colic, digestive aid, debility, appetite stim ulant,
gastric ulcer, cuts or wounds on hands or feet.
Cajanus cajan
Seed
Jaundice, coughs, bronchitis, itches, astringent, edem a, tum or, snake bite, stim ulant, edem a,
diarrhea, skin disorders.
Carissa carandas
Fruit
M alaria, epilepsy, nerve disorders, pain, headache, fever, insanity, anorexia, appetizer, blood
purifier, m yopathic spasm , dog bite, coughs, colds, itches, leprosy.
Cinnam om um tam ala
Leaf
D iabetes, flatulency, sore throat, tum or, coughs, cold, to m aintain strong teeth, im potency,
hypocholesterolem ic, stim ulant, itches, astringent, colic, antidote to poison, scars, anorexia,
indigestion, diarrhea, piles, derm atitis, jaundice, indigestion, carm inative, biliary disorders.
Cinnam om um
Bark
Tonic, hypocholesterolem ic, cardiac disorders, debility, dysentery, growth prom oter, appetite
zeylanicum
stim ulant, laxative, anorexia, low sperm count, rheum atism , biliary disorders, diabetes, to
reduce nervous tension, to increase m em ory, colds, to stop vom iting, headache, rheum atic
pain.
Coccinia grandis
Leaf
D iabetes, edem a, eye diseases, carm inative, hypertension, fever, inflam m ation, headache,
typhoid, sunstroke, coughs, nerve depressant, jaundice, stom ach pain, dizziness, m ental
disorders, respiratory disorders, eczem a, acne, leucorrhea, diarrhea, dysentery, blood
dysentery, increased tem perature of hands or head, bloating, blood disorders, derm atitis,
m yopathic spasm , baldness, scars, leukoderm a, lesions of the tongue, burning sensations in
hands or feet, insanity, bed wetting in children.
D illenia indica
Fruit
Cholera, purgative, antidote to poison, anti-hem orrhagic, anorexia, dysentery, appetizer,
abortifacient, stom ach pain, astringent, fever, coughs, appetite stim ulant, acidity, rheum atoid
arthritis, rheum atic pain, epilepsy, to increase lactation, low sperm count, boils, sprains,
debility, headache, hypertension, food toxicity.
Ferula asafoetida
Seed
Asthm a.
M anilkara zapota
Fruit
H epatic disorders, dysentery, tonic, appetizer, hypertension, diseases arising out of m alnutrition,
astringent, fever.
M entha arvensis
Leaf, stem
D ysentery, indigestion, stom ach pain.
M oringa oleifera
Leaf, fruit
Colds, fever, joint pain, gout, hypertension, constipation, acidity, epilepsy, skin eruptions,
leukoderm a, tonic, helm inthiasis, body pain, chicken pox, stim ulant, vom iting-induced stom ach
pain, em etic, carm inative, toothache, cracked foot, sterility, cancer, skin lesions, constipation,
indigestion, edem a, wounds, eczem a, boils, m yopathic spasm s, night blindness, derm atitis,
hernia, cardiovascular disorders, snake bite, paralysis, tetanus, rheum atoid arthritis, waist pain,
spleen enlargem ent, sedative, cathartic, diabetes, leprosy, conjunctivitis, pain.
Nym phaea nouchali
Leaf, stem
Indigestion, cardiovascular disorders, anti-hem orrhagic, stom ach pain, cancer, m enstruation
control, astringent, diarrhea, indigestion, diabetes.
Phyllanthus em blica
Fruit
Appetizer, gonorrhea, toothache, itches, leucorrhea, arteriosclerosis, diabetes, jaundice, eye
diseases, heatstroke, edem a, gastrointestinal disorders (stom ach pain, acidity, constipation,
diarrhea, dysentery, indigestion), body ache, appetite stim ulant, im potency, debility, anem ia,
fever, sudden unconsciousness, alopecia, skin diseases, to m aintain healthy hair, hair loss and
graying of hair, to m aintain strong teeth, fistula, sore throat, pain, sex stim ulant, jaundice,
to strengthen body organs (heart, stom ach, liver, m uscle, nerves), hepatitis, cold, loss of taste,
anorexia, burning sensations during urination, acne, m arks on face, to increase facial
com plexion.
Spilanthes acm ella
Leaf
To stop bleeding from gum s, dysentery, anem ia, toothache, oral lesions, stom ach pain,
gastrointestinal problem s, insect repellent, erectile dysfunction, to increase sperm count, head
infections.
Syzygium aromaticum Flower bud
Coughs, debility, to increase m ental alertness.
Term inalia belerica
Fruit
Constipation, sexual diseases, leprosy, piles, diarrhea, dysentery, blood dysentery, tonic, fever,
erectile dysfunction, coughs, indigestion, im potency, sex stim ulant, edem a, respiratory
problem s, hair tonic, appetite stim ulant, acidity, nerve stim ulant, edem a, inflam m ation, to
increase sensitivity of the senses, anorexia, headache, nerve stim ulant, hernia, typhus,
stim ulant, intestinal infection, skin diseases, constipation, asthm a, allergy, to m aintain healthy
body organs (heart, lungs, liver), lung problem s, liver dysfunctions, bloating, untim ely
graying of hair.
Term inalia chebula
Fruit
Cancer, jaundice, bronchitis, indigestion, piles, syphilis, leucorrhea, conjunctivitis, tum or, itches,
cardiovascular disorders, tuberculosis, heatstroke, ulcer, energy stim ulant, burns, low sperm
count, debility, inflam m ation, purgative, coughs, urinary troubles, carm inative, asthm a, biliary
problem s, jaundice, stim ulation of appetite, digestive aid, acidity, bloating, constipation, hair
loss, leprosy, edem a, m alaria, hepatitis, hoarseness, sore throat, leucorrhea, helm inthiasis,
pain, hepatic disorders, respiratory problem s, acne, m arks on face, to im prove facial
com plexion.
Table 2:
Discussion
A number of plants classified as functional foods (Table 2) have been studied scientifically for their
nutritional content and pharmacological activities. This discussion will provide an overview of some of the
872
more important plant species. The leaves of Spilanthes acmella and Dillenia indica are consumed by Khasi
tribal women of India as unconventional wild edibles to supplement their regular diet (Agrahar, 2006). In the
Sri Lankan traditional medicine, Spilanthes acmella flowers are used for their diuretic effects; this has been
confirmed in scientific studies conducted in rats using cold extract of flowers (Ratnasooriya, 2004) and thus
can have therapeutic uses in edema. Ethanol extracts of flower buds of the plant reportedly exhibited inhibitory
activities on pancreatic lipase and so can be a potential source to reduce obesity (Ekanem, 2007). N-isobutyl4,5-decadienamide isolated from the flowers of the plant has been reported to possess analgesic activity
(Ansari, 1988). In Taiwan, the plant is used as a common spice and has been administered for years in
traditional folk medicine to cure toothache, stammering, and stomatitis. A bio-active compound, spilanthol has
been isolated from the plant which demonstrated anti-inflammatory effect on murine macrophages by downregulating lipopolysaccharide-induced inflammatory mediators (W u, 2008). Other reported bio-active compounds
with good anti-oxidant activities, isolated from volatile oil from fresh leaves of this plant include germacreneD, trans-b-caryophyllene, b-elemene, nor-copaanone and bicyclogermacrene (Kawaree, 2008). Antioxidant and
vasorelaxant activities of extracts of the plant have also been demonstrated (W ongsawatkul, 2008). In Thai
traditional medicine, the plant is used to treat toothache, rheumatism, and fever. A number of bio-active
compounds isolated from chloroform and methanol extracts of the plant showed inhibitory activities against
a number of microorganisms like Corynebacterium diptheriae and Bacillus subtilis. The compounds included
phenolics like vanillic acid, trans-ferulic acid, and trans-isoferulic acid; coumarin (scopoletin); and triterpenoids
like 3-acetylaleuritolic acid, b-sitostenone, stigmasterol and stigmasteryl-3-O-b-D-glucopyranosides, in addition
to a mixture of stigmasteryl- and b-sitosteryl-3-O-b-D-glucopyranosides (Prachayasittikul, 2009). Taken together,
it may be concluded that the available studies justify the use of this plant has a functional food.
Partaking of Triphala (formulation from the dried fruits of three plants Phyllanthus emblica, Terminalia
belerica and Terminalia chebula) has been described in the ancient Indian Ayurvedic medicine to be good for
maintaining healthy heart conditions as well as a therapeutic agent for heart diseases. Since then, numerous
reports have been published on the preventive and curative properties of the fruits of these plants taken in
combination or individually. Feeding of a dried powder of fruits from the three plants have been shown to
reduce total cholesterol, LDL-cholesterol and triglycerides in hypercholesterolemic rats and to increase excretion
of bile acids (Nalini, 1999). W hen administered individually, the fruits of the plants were found to reduce
cholesterol in cholesterol-induced hypercholesterolemia and atherosclerosis in rabbits (Thakur, 1988). The
methanolic extract of fruits of the three plants, individually or in combination, reportedly showed antioxidant
potential in vitro and anti-diabetic activities in alloxan-induced diabetic rats (Sabu, 2002). Both acetone and
methanol extracts of Terminalia belerica and Terminalia chebula reportedly showed a broad spectrum of
antibacterial activity including inhibition of methicillin-resistant Staphylococcus aureus (Aqil, 2005). Pretreatment of mice with aqueous extract of Terminalia belerica fruits has been shown to confer protection
against experimental Salmonellosis and result in total survival of animals when challenged with lethal doses
of Salmonella typhimurium (M adani, 2008). Alcoholic extracts of fruits of Phyllanthus emblica and Terminalia
belerica conferred protective effects in isoproterenol-induced myocardial necrosis in rats (Tariq, 1977). The
antioxidant potential of Terminalia belerica (fruit), Terminalia chebula (fruit), and Nymphaea nouchali (flower)
has been reported and attributed to the presence of phenolic compounds like hydroxybenzoic acid derivatives,
hydroxycinnamic acid derivatives, flavonol aglycons and their glycosides (Saleem, 2001). Gallic acid, present
in fruits of Terminalia belerica has been found to have a protective effect against carbon tetrachloride-induced
hepatotoxicity and kidney damages in rats (Shukla, 2005; Jadon, 2007).
Analysis of Terminalia belerica fruits indicated that they are enriched in iron, phosphorus, cobalt and
selenium (Garg, 2005). The fruits of Terminalia chebula have been found to be enriched in magnesium (Garg,
2007). It has also been reported that the fruit tissue of Terminalia chebula contained 10.3 and 14.5 times more
vitamin C and protein, respectively when compared with commercial apples. The recommended dietary
allowance for selenium, potassium, manganese, iron and copper can also be met if 100g of the raw fruit is
taken (Barthakur, 1991). The fruits of Terminalia belerica and Terminalia chebula have been found to be rich
sources of gallic acid; the leaves and fruits of Terminalia belerica for ellagic acid; and the leaves of Moringa
oleifera for kaempferol (Bajpai, 2005). All the above three compounds are bio-active, with gallic and ellagic
acid being strong anti-oxidants and so can serve as preventing damages caused by cardiovascular disorders,
hypertension, diabetes and a host of other disorders. In fact, the ripe fruits of Terminalia chebula have been
postulated to possess the potential to play a role in the hepatic prevention of oxidative damage in living
systems (Lee, 2005). Chemical analysis of edible fruit tissues of Phyllanthus emblica showed that it had,
respectively, 3-fold and 160-fold protein and ascorbic acid concentrations than present in apples (Barthakur,
1991). The ascorbic acid (vitamin C) was found to be exceptionally stable in both fresh and dried fruits
(Shishoo, 1997). The fruits also contain flavonoids, which have been shown to inhibit hepatic HMG CoA
reductase activity and reduce lipid levels in serum and tissues of rats with hyperlipidemia (Anila). Powdered
873
dried fruits of Phyllanthus emblica has been suggested to become a useful remedy for Alzheimers disease on
account of its various beneficial effects such as improving memory, cholesterol lowering property and
anticholinesterase activity (Vasudevan, 2007); pre- and post-supplementation of fruit extract of the plant has
also been shown to significantly reduce arsenic-induced oxidative stress in liver (Sharma, 2009).
The fruit juice of Manilkara zapota has been shown to be one of the rich sources of sugars, proteins,
ascorbic acid, phenolics, carotenoids, and minerals like iron, copper, zinc, calcium and potassium; apart from
the nutrients, the fruit juice also showed antioxidant activity (Kulkarni, 2007). Activity-guided fractionation of
a methanol extract of fruits of this plant also revealed presence of a number of polyphenols with aniti-oxidant
activity; the highest activity was demonstrated by Me-4-O-galloylchlorogenate (Jun, 2003). The fruits of
Dillenia indica have also been found to be rich in phenolics with good antioxidant and free radical scavenging
activities (Abdille, 2005).
Among five Cinnamomum species studied, Cinnamomum zeylanicum leaves demonstrated highest DPPH
(1,1 -diphenyl-2-picrylhydrazyl) radical scavenging activity, total antioxidant activity and reducing power, while
Cinnamomum tamala leaves exhibited highest superoxide anion scavenging activity (Prasad, 2009).
Consumption of Cinnamomum species thus can be of beneficial effect for both preventing and ameliorating
diseases like cardiovascular disorders, hypertension, and diabetes for their antioxidant properties. Oleoresins
obtained from the bark of Cinnamomum zeylanicum also showed excellent antioxidant activity as demonstrated
through inhibition of primary and secondary oxidation products in mustard oil. Volatile oils obtained from
leaves and barks of this plant were also highly effective against a number of fungi tested (Singh, 2007). The
plant is enriched in micro-nutrients like iron, cobalt, chromium, sodium, potassium, phosphorus and zinc
(Singh, 2006). Eugenol, linalool, b-caryophyllene and caryophyllene oxide has been reported to be the major
components in the leaf oil of Cinnamomum tamala (Baruah, 2005; Ahemd, 2000). Eugenol is an antioxidant
and is known to protect nicotine-induced superoxide mediated oxidative damage in murine peritoneal
macrophages in vitro (Kar, 2009). Linalool has been reported to possess antiinflammatory and antinociceptive
properties including attenuation of allodynia in neuropathic pain induced by spinal nerve ligation in mice
(Berliocchi, 2009). Thus the leaves of this plant, which are used as spice can be of both protective and curative
values in different sorts of ailments causing pain or oxidative damages. Additionally, the leaves of this plant
are known to contain a number of bio-active flavonoids like kaempferol, quercetin, myricetin, kaempferol-3-Orhamnoside and quercitrin (Singh, 2002). The antioxidant property and presence of polyphenols (which are
antioxidants) have been confirmed in leaves of this plant using rat brain synaptosomes from control and
streptozotocin-induced diabetic rats as a model system (Devi, 2007). Taken together, the various Cinnamomum
species, which has been used as spices for hundreds of years in the Indian sub-continent and elsewhere can
be effective food supplements and so can be characterized as functional foods.
The seeds of Cajanus cajan, which are eaten as pulses throughout Bangladesh are known to have a high
content of potassium and phosphorus and moderate content of calcium and magnesium. The seeds also contain
iron, zinc, copper and manganese. Also because of its protein content (19.34%), it is considered as a most
important grain legume for human nutrition in the protein-deficient countries of the world (Nwokolo, 1987).
Since the seeds of the plant are used in the folk medicinal system of Bangladesh to combat diverse ailments
like jaundice, coughs, bronchitis, itches, astringent, edema, tumor, snake bite, stimulant, edema, diarrhea, and
skin disorders, this plant can also be considered an important functional food.
For a developing country like Bangladesh, it is important to identify functional foods, which can be
consumed on a regular basis by the population to serve both nutritional and medicinal purposes. The present
survey, besides collecting information on medicinal plants, also analyzed those plants with the objective of
determining which medicinal plant can serve as a functional food. Since a number of plants have been
identified, which can serve the dual purposes of medicinal and nutritive values they can be targeted for mass
cultivation and conservation. At the same time, the population can be made aware of the consumption values
of these plants or plant parts, which in turn can lead to reduced health costs, prevention and cure of a number
of prevalent diseases, and an improved diet.
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