Jchen Autoimmune LN

Intro to Herb-Drug Interactions for the
Collection Formulas, Part II

By
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Clinical Manual of Oriental Medicine, 2 edition

CD Manual of Oriental Medicine, v.2
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Collection Formulas:
Effects, Side Effects, Interactions
Intro to Herb-Drug Interactions for
the Collection Formulas, Part II
John K. Chen
John K. Chen
L.Ac., O.M.D., Pharm.D., Ph.D.
Pharm.D., Ph.D., O.M.D., L.Ac.
Lotus Institute Of Integrative Medicine

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Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine
Pathogen
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Wind, cold, heat, damp, etc.
Innate Immunity:
Barrier (skin, mucous);
Cellular (macrophage, NK cells)
Autoimmune Diseases
wei (defensive) level
Acquired Immunity:
T cells, B cells
Acute Inflammation:
Redness
Warmth
Swelling
Pain
Chronic Inflammation:
Cell lysis/apoptosis
Tissues/organs destruction
Loss of organs, functions
qi (energy) level
ying (nutritive) level
Xue (blood) level
Autoimmune Diseases
Endometriosis
Eosinophilic esophagitis
Eosinophilic fasciitis
Erythema nodosum
Experimental allergic
encephalomyelitis
Evans syndrome
Fibromyalgia**
Fibrosing alveolitis
Giant cell arteritis (temporal
arteritis)
Giant cell myocarditis
Glomerulonephritis
Goodpastures syndrome
Granulomatosis with
Polyangiitis (GPA)
Graves disease
Guillain-Barre syndrome
Hashimotos encephalitis
Hashimotos thyroiditis
Hemolytic anemia
Henoch-Schonlein purpura
Herpes gestationis
Hypogammaglobulinemia
Idiopathic thrombocytopenic
purpura (ITP)
IgA nephropathy
IgG4-related sclerosing disease
Immunoregulatory lipoproteins
Inclusion body myositis
Interstitial cystitis
Juvenile arthritis
Juvenile diabetes (Type 1
diabetes)
Juvenile myositis
Kawasaki syndrome
Lambert-Eaton syndrome
Leukocytoclastic vasculitis
Lichen planus
Lichen sclerosus
Ligneous conjunctivitis
Linear IgA disease (LAD)
Acute Disseminated
Encephalomyelitis (ADEM)
Acute necrotizing hemorrhagic
leukoencephalitis
Addisons disease
Agammaglobulinemia
Alopecia areata
Amyloidosis
Ankylosing spondylitis
Anti-GBM/Anti-TBM nephritis
Antiphospholipid syndrome
(APS)
Autoimmune angioedema
Autoimmune aplastic anemia
Autoimmune dysautonomia
Autoimmune hepatitis
Autoimmune hyperlipidemia
Autoimmune immunodeficiency
Autoimmune inner ear disease
(AIED)
Autoimmune myocarditis
Autoimmune oophoritis
Autoimmune pancreatitis
Autoimmune retinopathy
Autoimmune thrombocytopenic
purpura (ATP)
Autoimmune thyroid disease
Autoimmune urticaria
Axonal & neuronal
neuropathies
Balo disease
Behcets disease
Bullous pemphigoid
Cardiomyopathy
Castleman disease
Celiac disease
Chagas disease
Chronic fatigue syndrome**
Chronic inflammatory
demyelinating polyneuropathy
(CIDP)
Chronic recurrent multifocal
ostomyelitis (CRMO)
Churg-Strauss syndrome
Cicatricial pemphigoid/benign
mucosal pemphigoid
Crohns disease
Cogans syndrome
Cold agglutinin disease
Congenital heart block
Coxsackie myocarditis
CREST disease
Essential mixed
cryoglobulinemia
Demyelinating neuropathies
Dermatitis herpetiformis
Dermatomyositis
Devics disease (neuromyelitis
optica)
Discoid lupus
Dresslers syndrome
Autoimmune Diseases
Lupus (SLE)
Lyme disease, chronic
Menieres disease
Microscopic polyangiitis
Mixed connective tissue
disease (MCTD)
Moorens ulcer
Mucha-Habermann disease
Multiple sclerosis
Myasthenia gravis
Myositis
Neuromyelitis optica (Devics)
Neutropenia
Ocular cicatricial pemphigoid
Optic neuritis
Palindromic rheumatism
PANDAS
Paraneoplastic cerebellar
degeneration
Paroxysmal nocturnal
hemoglobinuria (PNH)
Parry Romberg syndrome
Parsonnage-Turner syndrome
Pars planitis (peripheral uveitis)
Pemphigus
Peripheral neuropathy
Perivenous encephalomyelitis
Pernicious anemia
POEMS syndrome
Polyarteritis nodosa
Type I, II, & III autoimmune
polyglandular syndromes
Polymyalgia rheumatica
Polymyositis
Postmyocardial infarction
syndrome
Postpericardiotomy syndrome
Progesterone dermatitis
Primary biliary cirrhosis
Primary sclerosing cholangitis
Psoriasis
Psoriatic arthritis
Idiopathic pulmonary fibrosis
Pyoderma gangrenosum
Pure red cell aplasia

Raynauds phenomenon
Reactive Arthritis
Reflex sympathetic dystrophy
Reiters syndrome
Relapsing polychondritis
Restless legs syndrome
Retroperitoneal fibrosis
Rheumatic fever
Rheumatoid arthritis
Sarcoidosis
Schmidt syndrome
Scleritis
Scleroderma
Sjogrens syndrome
Sperm & testicular
autoimmunity
Stiff person syndrome
Subacute bacterial endocarditis
(SBE)
Susacs syndrome
Sympathetic ophthalmia
Takayasus arteritis
Temporal arteritis/Giant cell
arteritis
Thrombocytopenic purpura
(TTP)
Tolosa-Hunt syndrome
Transverse myelitis
Type 1 diabetes
Ulcerative colitis
Undifferentiated connective
tissue disease (UCTD)
Uveitis
Vasculitis
Vesiculobullous dermatosis
Vitiligo
Wegeners granulomatosis

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Gardenia Complex
Gardenia Complex
Any excess conditions characterized by

heat, fire and toxins
Excess fire in all three jiaos
Infectious diseases with fever
Inflammatory conditions with swelling,
inflammation, burning sensations and pain
Diseases with high blood pressure and fast
heart rate
Chinese Actions
Gardenia Complex
Zhi Zi (Fructus Gardeniae)
Bian Xu (Herba Polygoni

Avicularis)
Chai Hu (Radix Bupleuri)
Che Qian Zi (Semen
Plantaginis)
Dang Gui (Radix Angelicae
Sinensis)
Di Huang (Radix Rehmanniae)
Fu Ling (Poria)
Gan Cao (Radix et Rhizoma
Glycyrrhizae)
Geng Mi (Semen Oryzae)
Huang Bo (Cortex Phellodendri
Chinensis)
Huang Qin (Radix Scutellariae)
Long Dan (Radix et Rhizoma

Gentianae)
Mu Dan Pi (Cortex Moutan)
Shan Yao (Rhizoma
Dioscoreae)
Shan Zhu Yu (Fructus Corni)
Shi Gao (Gypsum Fibrosum)
Shu Di Huang (Radix
Rehmanniae Praeparata)
Ze Xie (Rhizoma Alismatis)
Zhi Mu (Rhizoma
Anemarrhenae)
Gardenia Complex
Clears heat
Purges fire
Eliminates toxins
Western Actions
Antibiotic effect to treat infection
Anti-inflammatory and analgesic
effects to reduce swelling and relieve
pain
Antihypertensive effect to reduce blood
pressure
Hepatoprotective effect to treat
hepatitis and liver cirrhosis
Cholagogic effect to treat jaundice
Gastrointestinal effect to decrease
production and secretion of stomach
acid
Antipyretic effect to reduce body
temperature
Immunosuppressive:
significant inhibition of
human peripheral
blood T cells and IL-2
secretion.[i]
Anti-inflammatory:
suppresses vascular
inflammation via
inhibition of tumor
necrosis factor (TNF)alpha.[i]
[i] Chang WL, Wang HY, Shi LS, Lai JH, Lin
HC. Immunosuppressive iridoids from the
fruits of Gardenia jasminoides. School of
Pharmacy, National Defense Medical Center,
National Defense University, Taipei, Taiwan
114, Republic of China. J Nat Prod. 2005
Nov;68(11):1683-5.
[i] Hwang SM, Lee YJ, Yoon JJ, Lee SM,

Kang DG, Lee HS. Gardenia jasminoides
inhibits tumor necrosis factor-alpha-induced
vascular inflammation in endothelial cells.
Professional Graduate School of Oriental
Medicine, Wonkwang University, Chonbuk,
Republic of Korea. Phytother Res. 2010
Jun;24 Suppl 2:S214-9.
Supplementary Formulas
Bai Hu Tang (White Tiger Decoction)
Upper jiao
Long Dan Xie Gan Tang (Gentiana

Decoction to Drain the Liver)
Middle jiao
Zhi Bai Di Huang Wan (Anemarrhena,

Phellodendron, and Rehmannia Pill)
Lower jiao
With bacterial infections, add Herbal ABX.

With lung infection, combine with Respitrol (Heat) or Pinellia
XPT.
With infection of the ear, nose and throat, add Herbal ENT.
With stomach or duodenal ulcer, combine with GI Care.
With stomach or intestinal infection, combine with GI Care II.
With hypertension, combine with Gastrodia Complex or
Gentiana Complex.
With liver and gallbladder disorders, add Liver DTX.
With re bi (heat painful obstruction), add Flex (Heat).
With unknown swelling or hard lesions, add Resolve (AI).

Clinical Notes
Clinical Notes
Gardenia Complex and Herbal ABX are two

formulas with strong and broad-spectrum heatclearing effects.
Gardenia Complex incorporates numerous antibiotic

herbs for two important reasons.
Gardenia Complex is designed to purge heat in the

organs due to internal imbalances or improper dietary
intake such as excessive spicy or greasy food or
lifestyle (lack of sleep, excessive smoking, etc).
Herbal ABX clears heat and detoxifies, and is best for
infection that is contracted from outside sources, such
as influenza or urinary tract infection.
Therefore, although both formulas clear heat,

their use should still be distinguished.
First, the use of multiple herbs within an herbal formula has been
shown to increase the antibiotic effect more than ten-folds.
Second, isolated use of single ingredients is often ineffective and
increases the risk of development of bacterial and viral
resistance.[i]
Given these two reasons, it is necessary to combine

herbs with appropriate properties to ensure effectiveness
in treating the infection and minimizing the potential risk of
the micro-organisms developing resistance and/or
mutation.
[i] Zhong Yao Xue (Chinese Herbology), 1988; 140:144
Cautions & Contraindications
Case Studies
This formula is contraindicated in patients who have

generalized weakness and deficiency. It is also
contraindicated during pregnancy and nursing.
This herbal formula contains herbs that invigorates blood
circulation, such as Dang Gui (Radix Angelicae Sinensis).
Therefore, patients who are on anticoagulant or
antiplatelet therapies, such as Coumadin (warfarin),
should use this formula with caution, or not at all, as there
may be a higher risk of bleeding and bruising.[i],[ii],[iii]
K.B., a 62-year-old female, presented with

constant daily fever for two weeks. There were no
signs of infection; however, additional symptoms
of slight anger, irritability, thirst, and slight red
eyes were present. Her blood pressure was
132/72 mmHg. Though the fever was of unknown
origin, the TCM diagnosis was Liver Fire.
Gardenia Complex was administered four
capsules three times daily. The fever cleared in
two days and did not return. Her anger and
irritability had also lessened. Submitted by A.I.,
Hilo, Hawaii.
[i] Chan K, Lo AC, Yeung JH, Woo KS. Journal of Pharmacy and Pharmacology 1995 May;47(5):402-6.
[ii] Pharmacotherapy 1999 July;19(7):870-876.
[iii] European Journal of Drug Metabolism and Pharmacokinetics 1995; 20(1):55-60.
Additional Information
LPS Support
Nutrition
Lifestyle Instructions

Systemic lupus erythematosus (SLE)
Traditional Points
Balance Method by Dr. Richard Tan
Master Tungs Points by Dr. Brad Whisnant
Distal Needling Acupuncture by Robert Doane
Ear Acupuncture
Traditional Points
Auricular Medicine by Dr. Li-Chun Huang
Lupus with inflammation in joints, tendons, and

other connective tissues and organs
Lupus with arthritis, mouth sores, skin rash,
facial rash, hair loss, depression, fever,
sunlight sensitivity, extreme fatigue, joint pain,
muscle pain and weakness, anemia, malar
flush, headache, general malaise, and in
severe cases, destruction of vital organs.
Some people may show only a few symptoms,
others may have them all.

LPS Support
Chinese Actions
Clears heat
Eliminates toxins
Nourishes yin, tonifies
blood, and promotes
generation of body
fluids
LPS Support
Western Actions
Inhibits and
suppresses the growth
and multiplications of
cells
Anti-inflammatory
effect to reduce
swelling and
inflammation
Bai Hua She She Cao (Herba Hedyotis)

Ban Zhi Lian (Herba Scutellariae Barbatae)
Chi Shao (Radix Paeoniae Rubrae)
Hong Hua (Flos Carthami)
Hu Zhang (Rhizoma et Radix Polygoni Cuspidati)
Ji Xiang Teng (Caulis Paederiae)
Jin Yin Hua (Flos Lonicerae Japonicae)
Lian Qiao (Fructus Forsythiae)
Mo Han Lian (Herba Ecliptae)
Tao Ren (Semen Persicae)
Xuan Shen (Radix Scrophulariae)
Ye Ju Hua (Flos Chrysanthemi Indici)
Zhi Mu (Rhizoma Anemarrhenae)

Ban Zhi Lian (Herba Scutellariae Barbatae)
Jin Yin Hua (Flos Lonicerae Japonicae)


and Ban Zhi Lian (Herba Scutellariae
Barbatae) inhibit and suppress the growth
and multiplication of cells to address the
autoimmune aspect of lupus.[i],[ii]
Jin Yin Hua (Flos Lonicerae

Japonicae) has demonstrated a
broad spectrum of inhibitory
actions against Staphylococcus
aureus, beta-hemolytic
streptococcus, E. coli, Bacillus
dysenteriae, Vibrio cholerae,
Salmonella typhi, Diplococcus
pneumoniae, Diplococcus
meningitidis, Pseudomonas
aeruginosa, and
Mycobacterium tuberculosis.[i],[ii]
[i] Zhong Yao Xue (Chinese Herbology), 1998; 204

[ii] Ren Min Wei Sheng Chu Ban She (Journal of People's Public Health), 1988; 302
[i] Xin Yi Xue (New Medicine), 1975; 6(3):155

[ii] Jiang Xi Xin Yi Yao (Jiangxi New Medicine and
Herbology); 1960;(1):34

has illustrated a broad
spectrum of inhibitory effects
against Staphylococcus aureus,
Diplococcus pneumoniae,
Bacillus dysenteriae, hemolytic streptococcus, betahemolytic streptococcus,
Neisseria catarrhalis,
Salmonella typhi, E. coli,
Mycobacterium tuberculosis,
Bacillus proteus, Bordetella
pertussis, Corynebacterium
diphtheriae, leptospira, and
some dermatophytes.[i]
Tao Ren (Semen Persicae)

Hong Hua (Flos Carthami)
Tao Ren (Semen Persicae) and Hong Hua (Flos
Carthami) both have anti-inflammatory functions.
Tao Ren (Semen Persicae) exerts its antiinflammatory and antiallergic effects via reduction
of histamine release from mast cells. Hong Hua
(Flos Carthami) exerts its anti-inflammatory
action via induction of heme oxygenase-1
expression.[i]
[i] Shan Xi Xin Yi Yao (New Medicine and Herbology

of Shanxi), 1980; 9(11):51

Di Huang (Radix Rehmanniae) has both
anti-inflammatory and antiallergic effects by
suppressing the expression of cytokines,
chemokines, and adhesion molecules.[ii]
[ii] Sung YY, Yoon T, Jang JY, Park SJ, Kim HK. Topical application of Rehmannia glutinosa extract inhibits mite
allergen-induced atopic dermatitis in NC/Nga mice. Center of Herbal Resources Research, Korea Institute of Oriental
Medicine, Daejeon 305-811, Republic of Korea. J Ethnopharmacol. 2011 Mar 8;134(1):37-44. Epub 2010 Dec 1.
[i] Jun MS, Ha YM, Kim HS, Jang HJ, Kim YM, Lee YS, Kim HJ, Seo HG, Lee JH, Lee SH, Chang KC. Antiinflammatory action of methanol extract of Carthamus tinctorius involves in heme oxygenase-1 induction.
Department of Pharmacology, School of Medicine, and Institute of Health Sciences, Gyeongsang National
University, 92 Chilam-dong, Jinju 660-751, Republic of Korea. J Ethnopharmacol. 2010 Oct 20.

Zhi Mu (Rhizoma Anemarrhenae) showed

significant analgesic and anti-inflammatory
effect for the treatment of osteoarthritis.
The antinociceptive and anti-inflammatory
effect of the herbs were similar or better
than celecoxib in the osteoarthritic animal
models.[i]
[i] Kang M, Jung I, Hur J, Kim SH, Lee JH, Kang JY, Jung KC, Kim KS, Yoo MC, Park DS, Lee JD, Cho YB. The
analgesic and anti-inflammatory effect of WIN-34B, a new herbal formula for osteoarthritis composed of Lonicera
japonica Thunb and Anemarrhena asphodeloides BUNGE in vivo. Central Research Institute, WhanIn Pharm. Co.,
Ltd, Yeongtong-Gu, Suwon-si, Republic of Korea. J Ethnopharmacol. 2010 Sep 15;131(2):485-96. Epub 2010 Jul 17.
With facial or skin rash, combine with Dermatrol (PS).

With arthritis, combine with Flex (Heat) or Flex (CD).
With nerve dysfunction, combine with Flex (NP).
With exterior wind-heat condition, add Lonicera
Complex.
With high fever, add Gardenia Complex.
With thirst, add Nourish (Fluids).
With Kidney yin deficiency manifesting chronic low-grade
fever, flushed cheeks, body pain, purpura, add Nourish.
With Kidney yin deficiency manifesting in organ or tissue
destruction, add Kidney Tonic (Yin).
Clinical Notes
Lupus may develop after taking certain

prescription medications. Symptoms
generally disappear after the drug is
discontinued. According to New England
Journal of Medicine, up to 10% of lupus
cases are related to drug reactions.
Therefore, drugs that are most likely to
cause lupus should be avoided, such as:
The main emphasis of this formula is to use

herbs to clear heat, eliminate toxins, and control
the autoimmune and inflammatory conditions of
lupus. Therefore, it contains many bitter and cold
herbs, which may consume qi and yin. If the
patient shows more signs and symptoms of such
deficiencies, additional herbs and formulas
should be given to strengthen the underlying
constitutions. See Supplementary Formula
section for details.
Apresoline (hydralazine), Procan

(procainamide), isoniazid and birth control pills.
Systemic lupus erythematosus (SLE) is an

autoimmune disorder. In theory, qi tonic herbs that
stimulate the immune system should be used with
caution. However, in clinical practice, these herbs may
still be indicated based on differential diagnosis.
Huang Qi (Radix Astragali):
Nutrition

stimulates cellular and humoral immunity, increases lymphocytes

and macrophages, promotes secretion of interferons.
Use only at a low dosage and only with addition of heat-clearing
and yin-nourishing herbs.
Ren Shen (Radix et Rhizoma Ginseng) and Xi Yang Shen

(Radix Panacis Quinquefolii)
stimulates cellular and humoral immunity, activates production of
antinuclear antibodies
Traditional Points
Ear Acupuncture
Traditional Points

Nourish
Fu Ling (Poria)
Gou Qi Zi (Fructus Lycii)
Huang Bo (Cortex Phellodendri Chinensis)
Ju Hua (Flos Chrysanthemi)
Shan Yao (Rhizoma Dioscoreae)
Shu Di Huang (Radix Rehmanniae Praeparata)
Nourish (Fluids)
Flex (MLT)
Bai He (Bulbus Lilii)

Bei Sha Shen (Radix Glehniae)
Da Zao (Fructus Jujubae)
Geng Mi (Semen Oryzae)
Mai Dong (Radix Ophiopogonis)
Nan Sha Shen (Radix Adenophorae)
Tian Dong (Radix Asparagi)
Xi Yang Shen (Radix Panacis Quinquefolii)
Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae
Praeparata cum Melle)
Bai Shao (Radix Paeoniae Alba)

Chu Shi Zi (Fructus Broussonetiae)
Chuan Niu Xi (Radix Cyathulae)
Dang Gui (Radix Angelicae Sinensis)
Dang Shen (Radix Codonopsis)
He Shou Wu (Radix Polygoni Multiflori)
Qian Nian Jian (Rhizoma Homalomenae)
Wu Jia Pi (Cortex Acanthopanacis)
Xu Duan (Radix Dipsaci)
Nourish
Nourish
Menopause: hot flashes, night sweats, fluctuation of body

temperature
Eyes and ears: blurry vision, dizziness, general visual
disturbance, fatigue of the eyes, optic nerve atrophy, mild
cases of glaucoma, and macular degeneration
Kidneys: chronic nephritis, nephrotic syndrome, chronic
renal failure
Bladder: frequent urination, urinary incontinence
Liver: chronic hepatitis
Pancreas: diabetes mellitus
Skin: dryness with lack of elasticity of the skin throughout
the body
Fu Ling (Poria)
Ju Hua (Flos Chrysanthemi)
Shan Yao (Rhizoma Dioscoreae)
Shu Di Huang (Radix Rehmanniae Praeparata)

Nourish
Effect on Kidney
Liu Wei Di Huang Wan (Six-Ingredient Pill

with Rehmannia)
Zhi Bai Di Huang Wan (Anemarrhena,
Phellodendron, and Rehmannia Pill)
Qi Ju Di Huang Wan (Lycium Fruit,
Chrysanthemum, and Rehmannia Pill).
Liu Wei Di Huang Wan (Six-Ingredient Pill with

Rehmannia) has been shown to increase blood
perfusion to the kidneys, improve kidney
functions, and reduced protein and uric acid in
the urine.[i] Clinically, it has been used effectively
to treat 6 patients with edema and proteinuria due
to nephrotic syndrome,[ii] 12 patients with chronic
renal failure,[iii] and 30 patients with nephrotic
syndrome.[iv]
[i] Zhong Yi Fang Ji Xian Dai Yan Jiu (Modern Study of Medical Formulae in Traditional Chinese Medicine)
1997;710.
[ii] Zhe Jiang Zhong Yi Za Zhi (Zhejiang Journal of Chinese Medicine) 1988;6:244.
[iii] Shi Yong Zhong Yi Nei Ke Za Zhi (Journal of Practical Chinese Internal Medicine) 1993;3:142.
[iv] Shi Yong Zhong Yi Za Zhi (Journal of Practical Chinese Medicine) 1995;6:10.
Effect on Liver
Effect on Pancreas
Liu Wei Di Huang Wan (Six-Ingredient Pill with

Rehmannia) illustrates hepatoprotective effect to
protect the liver against damages induced by
such substances as carbon tetrachloride,
thioacetamide, and prednisolone.[i]
Clinically, Liu Wei Di Huang Wan (Six-Ingredient
Pill with Rehmannia) has been used effectively to
treat 65 patients with chronic hepatitis.[ii]
Clinically, herbs in this formula, such as Gou Qi

Zi (Fructus Lycii), Shan Yao (Rhizoma
Dioscoreae), Shan Zhu Yu (Fructus Corni) and
Zhi Mu (Rhizoma Anemarrhenae), have been
used successfully to treat adult-onset
diabetes,[i],[ii] and non-insulin dependant
diabetes,[iii],[iv] and diabetes with
complications.[v]
[i] Zhong Guo Yao Ke Da Xue Xue Bao (Journal of University of Chinese Herbology) 1989;6:951.
[ii] Nei Meng Gu Zhong Yi Yao (Traditional Chinese Medicine and Medicinals of Inner Mongolia) 1998;1:4.
[i] Yun Nan Yi Yao (Yunan Medicine and Herbology) 1983;3:181.

[ii] Hu Nan Zhong Yi Za Zhi (Hunan Journal of Chinese Medicine) 1997;6:7.
[iii] He Bei Zhong Yi (Hebei Chinese Medicine) 1999;11:35.
[iv] Hu Bei Zhong Yi Za Zhi (Hubei Journal of Chinese Medicine) 1992;2:20.
[v] Shang Hai Zhong Yi Yao Za Zhi (Shanghai Journal of Chinese Medicine and Herbology) 1991;10:23.
Herbal DTX
Herbal DTX
Chemical poisoning (i.e., insecticide, pesticide, herbicide,

artificial hormones and preservatives, chemical
compounds, chemical solvents, plastics, cleaning
products, pollutants, detergents, paint thinner, nail polish
remover, new carpet fibers and any other products that
may contain toxic fumes or fragrance)
Heavy metal poisoning (i.e., arsenic, lead, mercury) in
water, food and the environment
Air pollution (i.e., gas exhaust, fumes, perfumes, air
freshener, burned plastic, and other airborne toxins)
Food poisoning (i.e., tetrodotoxin, snake, and
mushrooms)
Chronic use and accumulation of drugs and their
metabolites
Chinese Actions
Clears heat and
eliminates toxins
Expels toxins
through urine and
stool
Nourishes yin
Tonifies Kidney and
Heart
Western Actions
General detoxification effect to treat
chronic exposure to and
accumulation of unwanted
substances, such as toxic
chemicals, herbicides and
pesticides, allergens, heavy metals,
drugs, and other industrial pollutants
and contaminants
Hepatoprotective effect to protect
the liver
Nephroprotective effect to protects
the kidneys

Herbal DTX
Fang Feng (Radix Saposhnikoviae)

Gan Cao (Radix et Rhizoma Glycyrrhizae)
Lu Dou (Semen Phaseoli Radiati)
Toxic foods and plants [i],[ii]
food poisoning (tetrodotoxin, snake, and mushrooms) [iii]
[iv]
Mushroom poisoning [v]
Pesticide poisoning [vi]
Drug poisoning (chloral hydrate, urethane, cocaine,
picrotoxin, caffeine, pilocarpine, nicotine, barbiturates,
mercury and lead) [vii]
Heavy metals [viii]
Bai Mao Gen (Rhizoma Imperatae)

Da Huang (Radix et Rhizoma Rhei)
Dan Shen (Radix et Rhizoma Salviae
Miltiorrhizae)
Fang Feng (Radix Saposhnikoviae)
Gan Cao (Radix et Rhizoma Glycyrrhizae)
Lu Dou (Semen Phaseoli Radiati)
Heavy metal poisoning
In one report, 278 patients were treated for

arsenic poisoning with an herbal decoction twice
daily consisting of Fang Feng (Radix
Saposhnikoviae), Lu Dou (Semen Phaseoli
Radiati), Gan Cao (Radix et Rhizoma
Glycyrrhizae) and sugar. At the end of the 28-day
treatment, 155 patients (55.76%) reported a
significant improvement in subjective signs and
symptoms, with normal levels of arsenic found
through urinalysis.[i]
For liver damage or hepatitis due to poisoning, or to

enhance the immediate effect, add Liver DTX.
For kidney damage or nephritis due to poisoning, add
Kidney DTX.
For mild nasal congestion and post-nasal drip, add
Magnolia Clear Sinus.
For severe nasal obstruction with yellow and sticky
discharge, add Pueraria Clear Sinus.
For difficulty breathing and feeling of chest tightness, add
Respitrol (Heat) or Respitrol (Deficient).
For unknown causes or strange symptoms of blood
stagnation, add Circulation (SJ).
[i] Shang Hai Zhong Yi Yao Za Zhi (Shanghai Journal of Chinese Medicine and Herbology), 1964; 8:22
[ii] Fu Jian Zhong Yi Yao (Fujian Chinese Medicine and Herbology), 1965; 4:44
[iii] Xin Zhong Yi (New Chinese Medicine), 1985; 2:34
[iv] Zhong Yao Tong Bao (Journal of Chinese Herbology), 1986; 11(10):55
[v] Xin Zhong Yi (New Chinese Medicine), 1978; 1:36
[vi] Zhe Jiang Zhong Yi Za Zhi (Zhejiang Journal of Chinese Medicine), 1965; 7:7
[vii] Zhong Yao Tong Bao (Journal of Chinese Herbology), 1986; 11(10):54
[viii] Xin Yi Xue (New Medicine), 1973; 7:6
[i] Xin Yi Xue (New Medicine), 1973; 7:6
Clinical Notes
Because of its effect to eliminate the accumulation of

toxins and enhance the functions of the liver and kidney,
Herbal DTX is a good formula for individuals who have
hypersensitivity to certain toxins, chemicals, and
environmental factors. Herbal DTX contains herbs that
will enhance the bodys natural ability to break down and
eliminate the buildup of toxins in the body. Herbal DTX is
a gentle formula that gradually and continuously remove
toxins from the body. It should be taken persistently for 6
to 12 months for optimal effect.
This formula is not recommended for the

following conditions:
Patients with an acute overdose or severe poisoning
should be treated in an emergency room or urgent
care center. Call 911 and send the patient to the
nearest emergency room immediately.
Patients with hematuria (blood in the urine) should be
treated with extreme caution because this symptom
may indicate the possibility of significant damage to the
kidney.
Patients who are disorientated or having a
seizure/epilepsy/convulsion associated with poisoning
should consult their medical doctor immediately.

The following warning statement is required by

the State of California: This product contains Da
Huang (Radix et Rhizoma Rhei). Read and follow
directions carefully. Do not use if you have or
develop diarrhea, loose stools, or abdominal pain
because Da Huang (Radix et Rhizoma Rhei) may
worsen these conditions and be harmful to your
health. Consult your physician if you have
frequent diarrhea or if you are pregnant, nursing,
taking medication, or have a medical condition.
This herbal formula contains herbs that

invigorates blood circulation, such as Dan
Shen (Radix et Rhizoma Salviae
Miltiorrhizae). Therefore, patients who are
on anticoagulant or antiplatelet therapies,
such as Coumadin (warfarin), should use
this formula with caution, or not at all, as
there may be a higher risk of bleeding and
bruising.[i]
Case Studies
Case Studies
Herbal DTX has been used with great

success in China for treatment of drug
overdose (sedatives and hypnotics),
accidental ingestion of rat poison, and other
adverse reactions. This formula has been
used with excellent results by itself, in
combination with drug treatment, or
following gastric lavage. Submitted by
W.C., Shanxi, China.
W.G, 23-year old male presented with toxicity

due to recreational drugs. TCM diagnosis was
toxic heat in the Liver as well as throughout the
entire body. For treatment, Liver DTX and
Herbal DTX were prescribed. The patient noticed
a significant detoxification in response to taking
both formulas. In comparison, he had noticed the
Liver DTX working more through the urine and
the Herbal DTX working throughout the entire
body. He was very in-tune with his body and
testified that these formulas were very helpful to
his condition. Submitted by B.S., Niceville,
Florida.
Comparative Analysis
Nutrition

In cases of chronic poisoning (from

chemicals, heavy metals, and various
environmental toxins), there are often many
vague, non-specific, non-diagnostic signs
and symptoms accompanied by normal
laboratory tests. Under these
circumstances, Western medicine struggles
to determine the exact diagnosis and
corresponding treatments.
Traditional Points
Ear Acupuncture
Traditional Points
[i] Chan K, Lo AC, Yeung JH, Woo KS. Journal of Pharmacy and Pharmacology 1995 May;47(5):402-406.

Liver DTX
Liver DTX
Liver detoxification: enhances the normal

metabolic and detoxification functions of
the liver
Liver damage with elevated liver enzymes
Hepatitis with or without jaundice
Liver cirrhosis caused by alcohol, drugs or
other chemicals
Addiction treatment: detoxifies liver from
alcohol, drugs and other chemicals
Chinese Actions
Liver DTX
Wu Wei Zi (Fructus Schisandrae Chinensis)
Studies have shown that administration of Wu

Wei Zi (Fructus Schisandrae Chinensis) is
associated with marked hepatoprotective effect
against various types of drugs and/or chemicalinduced toxicities.[i]
Bai Shao (Radix Paeoniae Alba)

Chai Hu (Radix Bupleuri)
Da Huang (Radix et Rhizoma Rhei)
Fu Ling (Poria)
Ge Hua (Flos Puerariae)
Hu Zhang (Rhizoma et Radix Polygoni Cuspidati)
Huang Qin (Radix Scutellariae)
Ma Bian Cao (Herba Verbenae)
Pu Tao Zi (Semen Vitis Vinifera)
Qing Pi (Pericarpium Citri Reticulatae Viride)
Shui Fei Ji (Fructus Silybi)
Yin Chen (Herba Artemisiae Scopariae)
Yu Jin (Radix Curcumae)
Clears heat and

eliminates toxins
Spreads the Liver qi
Drains dampness
Tonifies deficiency
Western Actions
Enhances the liver function by
increasing the regeneration of liver
cells
Protects the liver from damages
caused by alcohol, drugs or other
chemicals
Treats liver cirrhosis by preventing
and repairing liver damages
Antioxidant effects to neutralize free
radicals and prevent cell damages
Lowers elevated levels of hepatic
enzymes
[i] Zhong Hua Yi Xue Za Zhi (Chinese Journal of Medicine), 1974; (5):275
The mechanisms of hepatoprotective

function of Wu Wei Zi (Fructus Schisandrae
Chinensis) are attributed to alteration of
liver cell-membrane permeability to prevent
the entry of toxic substances, and
increased blood flow to the liver and
increased regeneration of liver cells.[i],[ii]
One study reported 85.3% rate of effectiveness

using 3g of powdered Wu Wei Zi (Fructus
Schisandrae Chinensis) three times daily to treat
102 cases of non-icteric infectious hepatitis.
Furthermore, one study reported that oral
ingestion of Wu Wei Zi (Fructus Schisandrae
Chinensis) in honey pills effectively lowered liver
enzymes in 67 of 80 patients with chronic
hepatitis.[i]
[i] Nagai, H. et al. Planta Medica. 55(1):13-17. 1989

[ii] Takeda, S. et al. Nippon Yakurigaku Zasshi. 88(4):321-30. 1986
[i] Zhong Yao Lin Chuan Xin Yong (New Clinical Applications of Chinese Medicine), 2001; 103

10
An herbal formula with Wu Wei Zi (Fructus

Schisandrae Chinensis) was used with a
97% rate of effectiveness (33 out of 34
patients) in treatment of chronic hepatitis.[i]
The use of Shui Fei Ji (Fructus Silybi) can

be traced back over 2,000 years to a Greek
reference when Pliny the Elder (A.D. 23-79)
first noted it had an excellent effect to
carry off bile.[i]
[i] Shan Xi Zhong Yi (Shanxi Chinese Medicine), 1988; 3:106
[i] Foster, S. Milk Thistle-Silybum Marianum, Botanical Series No. 305, Am. Botanical Council,
Austin TX 1991; 3-7
Today, Shui Fei Ji (Fructus Silybi) is well

documented for having both
hepatoprotective and nephroprotective
against Tylenol (acetaminophen)-induced
liver and kidney toxicities.[i]
Silymarin, one active compound from Shui

Fei Ji (Fructus Silybi), protects the liver by
changing the outer liver cell membrane and
preventing the entrance of toxins into the
liver cells.5,[i]
[i] Gopi KS, Reddy AG, Jyothi K, Kumar BA. Acetaminophen-induced Hepato- and Nephrotoxicity and Amelioration
by Silymarin and Terminalia chebula in Rats. Department of Pharmacology and Toxicology, College of Veterinary
Science, Hyderabad - 500030, Andhra Pradesh, India. Toxicol Int. 2010 Jul;17(2):64-6.
[i] Floersheim, GL. Medical Toxicology; 2:1. 1987
Clinical Notes
For heavy metal, chemical or environmental poisoning,

add Herbal DTX.
For compromised kidney function, use Kidney DTX.
For cholecystitis or gallstones with elevated liver
enzymes, combine with Dissolve GS.
Gentiana Complex may be combined with Liver DTX for
a synergistic effect to treat hepatic disorders.
For fatty liver, add Cholisma (ES).
With jaundice, add Yin Chen Hao Tang (Artemisia
Scoparia Decoction).
For dark complexion and blood stagnation, add
Circulation (SJ).
Elevation of liver enzymes is common in hepatitis. Though

Western medicine has treatments for lowering liver
enzymes, the results are sometimes unsatisfactory,
especially in chronic hepatitis B. Therefore, herbs that
clear heat, remove damp, strengthen the Spleen and
regulate the Liver are used to normalize liver enzyme
levels. In addition, small dosages of blood-activating and
stasis-removing herbs can be used together for their
synergistic effect. Patients should continue to take herbs
for a period of time after liver enzyme levels return to
normal to prevent rebound increase of liver enzymes.

11
Clinical Notes
Clinical Notes
Lab exams are extremely useful in

diagnosis, treatment and prognosis
assessment for patients with liver
dysfunction. Understanding the implications
of laboratory tests empowers health care
practitioners to effectively treat hepatic and
gallbladder disorders.
Liver cirrhosis is a common complication of

chronic hepatitis infection. To reduce the risk of
developing cirrhosis of the liver in chronic
hepatitis, use large dosages of Dan Shen (Radix
et Rhizoma Salviae Miltiorrhizae) with regular
dosages of Hong Hua (Flos Carthami). Addition
of Bie Jia (Carapax Trionycis) to the herbal
formula will further reduce the risk of developing
liver cirrhosis.
Liver DTX is contraindicated during pregnancy

and nursing. It should be used with caution in
cases of qi and yang deficiencies.
Do not use this formula to treat acute liver failure
such conditions must be sent to the emergency
room for immediate medical care.
The following warning statement is required by

the State of California: This product contains Da
Huang (Radix et Rhizoma Rhei). Read and follow
directions carefully. Do not use if you have or
develop diarrhea, loose stools, or abdominal pain
because Da Huang (Radix et Rhizoma Rhei) may
worsen these conditions and be harmful to your
health. Consult your physician if you have
frequent diarrhea or if you are pregnant, nursing,
taking medication, or have a medical condition.
Decrease the dosage to two capsules twice a day
if there is loose stool after taking the herbs.
Case Studies
Case Studies
A 41-year-old male complained of occasional

bouts of irritability. He had elevated liver
enzymes, elevated HCT and was positive for
Hepatitis C. The practitioner diagnosed his
condition as damp-heat in the Liver and
Gallbladder. After taking Liver DTX, the liver
enzyme levels tested within normal limits. The
patients medical doctor, after recognizing all
supporting evidence, encouraged the herbal
treatment wholeheartedly. Submitted by P.C.,
Stanwood, Washington.
A 36-year-old female patient presented with severe hangover

from excessive alcohol consumption. Clinical signs and
symptoms included nausea, vomiting, anorexia, frontal
headache, diarrhea, and extreme weakness and fatigue. Her
tongue was pale and flabby, with a moist, greasy tongue
coating. Her face was pale and puffy, with dark, sunken eyes.
The Western diagnosis was acute alcohol intoxication; the
TCM diagnosis was damp-heat in the Liver and Gallbladder,
with qi deficiency. Liver DTX was prescribed at four capsules
every four to six hours for one day. Within two hours after
taking the first dose, the patient reported that she felt 98%
improvement, and said that she had regained her strength and
appetite. She stated that her headache, nausea, vomiting and
diarrhea had all diminished. She took the second dose, ate a
large meal, and recovered from alcohol intoxication. Submitted
by C.L., Chino Hills, California.

12
Nutrition

Liver diseases, such as hepatitis and liver

cirrhosis, are serious and very complicated
diseases. In Western medicine, these conditions
are usually treated with interferon. These drugs,
however, have limited success, but are extremely
expensive and create significant number of
serious side effects, including dizziness,
confusion, coma, arrhythmia, heart failure,
leukopenia, thrombocytopenia, and many others.
In severe and life threatening cases, such as liver
cirrhosis and liver cancer, surgery may be
perform.
Traditional Points
Ear Acupuncture
Traditional Points
Kidney DTX
Chronic nephritic syndrome (nephritis,
glomerulonephritis)
Chronic nephrotic syndrome (nephropathy)
Chronic kidney disease with such signs and
symptoms as proteinuria, edema, soreness of the
lower back, fatigue, emaciation, flabby tongue,
greasy tongue coating, deep, thready or wiry
pulse
Note: This formula is not recommended for acute
kidney disorders.
Kidney DTX
Chinese Actions
Dispels dampness
Tonifies Kidney yin
Tonifies qi
Western Actions
Nephroprotective benefit to
restore the normal filtration and
excretion functions of the
kidney
Nephroprotective effect to
reduce the presence of protein
and blood in the urine
Antifibrosis activity to improve
ischemic microvasculature and
attenuate interstitial fibrosis
Diuretic effect to increase urine
output and eliminate water
accumulation
Kidney DTX
Huang Qi (Radix Astragali)
Huang Qi (Radix Astragali) has a

remarkable effect to treat kidney-related
disorders, such as proteinuria, nephritis,
nephropathy and glomerulonephritis.
Bai Mao Gen (Rhizoma Imperatae)

Du Zhong (Cortex Eucommiae)
Fu Ling (Poria)
Jin Ying Zi (Fructus Rosae Laevigatae)
Lu Xian Cao (Herba Pyrolae)
Mu Li (Concha Ostreae)
Shi Wei (Folium Pyrrosiae)

13
Pharmacologically, Huang Qi (Radix Astragali)

exerts the nephroprotective effect to improve
glomerular hyperfiltration state, and relieve
pathological changes of early diabetic
nephropathy.[i] Administration of Huang Qi (Radix
Astragali) is associated with numerous benefits in
patients with nephropathy by improving BUN,
SCr, CCr and urine protein).[ii]
Clinically, use of Huang Qi (Radix

Astragali) twice daily for 15 to 90 days was
effective in treating 16 out of 20 patients
with nephritis. Most patients also reported
symptomatic improvement as well as a
decrease of protein in the urine.[i]
[i] Hei Long Jiang Zhong Yi Yao (Heilongjiang Chinese Medicine and Herbology), 1982; 1:39
[i] Zhang J, Xie X, Li C, Fu P. Systematic review of the renal protective effect of Astragalus membranaceus (root) on
diabetic nephropathy in animal models. Department of Nephrology, West China Hospital of Sichuan University,
Chengdu 610041, China. J Ethnopharmacol. 2009 Nov 12;126(2):189-96. Epub 2009 Sep 6.
[ii] Li M, Wang W, Xue J, Gu Y, Lin S. Meta-analysis of the clinical value of Astragalus membranaceus in diabetic
nephropathy. Division of Nephrology, Huashan Hospital, Fudan University, Shanghai, China. J Ethnopharmacol.
2010 Oct 13.
Clinical Notes
For accumulation of environmental pollutant, chemical

compounds, and other toxins in the body, add Herbal
DTX.
For edema and water accumulation, add Herbal DRX.
For unknown cause of symptoms with blood stagnation in
patients with excess condition, add Circulation (SJ).
For dry mouth, deficiency heat symptoms, tinnitus or
dizziness, add Nourish or Nourish (Fluids).
For high blood pressure, add Gastrodia Complex.
For fever, headache, and nausea, add Herbal ABX.
With compromised liver function, add Liver DTX.
To effectively treat kidney disorder, it is extremely

important to identify and eliminate the cause(s). It is
important to make sure disease conditions that are known
to increase the risk and acceleration of kidney disorders
are well controlled, such as diabetes and lupus.
Furthermore, certain drugs, toxins and heavy metals are
known to cause kidney damage, and must be avoided,
such as certain antibiotics, analgesics, and antiepileptics.
Examples of environmental toxins include chemical
solvents, biological agents, herbicides and pesticides.
Examples of heavy metals include lead and cadmium.
Avoidance of such factors will significantly improve both
short- and long-term prognosis.
Clinical Notes
Clinical Notes
Though the use of herbs can treat kidney

disorders and restore the normal kidney
functions, this formula is not recommended
for acute renal diseases.
Kidney DTX is not suitable for acute
nephritis. Such conditions should be
referred to a medical doctor for immediate
treatment.
It is prudent to monitor progress objectively

with urine analysis. Such laboratory tests
will confirm the effectiveness of the
treatment and assist in the long-term
treatment strategy.

14
Case Studies
Case Studies
C.P., a 63- year-old female, presented with multiple symptoms

including low energy, pain located in the areas of the elbow,
hip, back, and neck. Additional symptoms included the face
and other parts of the body being puffy. Objective findings were
BUN level of 53.0 mg/dL, creatinine level of 2.6 mg/dL, and
calcium level of 12 mg/dL. The practitioner diagnosed this
condition as Kidney yin deficiency with dampness, along with
Kidney failure at stage three. She was prescribed Kidney DTX
and was advised to change her diet to a low protein diet. After
four months of taking the herbs, her BUN levels became
normal, the creatinine levels dropped but were still slightly high,
and the calcium levels became normal. The Western doctors
involved with treating this patient were amazed at the change
in values of BUN and creatinine as a result of the herbs. They
had commented that they had never seen this happen before.
Submitted by T. S. Tehachapi, California.
L.T., 64-year old female presented with the beginning of

kidney declination due to long term taking of both her antiinflammatories and high blood pressure medications for
twenty years. Blood pressure was 130/80 mmHg and her
heart beat was 72 beats per minute. TCM diagnosis was
Kidney and Liver yin deficiencies; the Western diagnosis
was kidney failure (beginning stage). Kidney DTX was
prescribed and directed to take for 9 months. After going
and seeing a Western doctor and being offered minimal
help with a negative outlook, the patient lived an
additional three years, which had been more than the
Western doctor had predicted. Submitted by J.L., San
Diego, California.
Nutrition

Kidney diseases, such as chronic nephritic

syndrome, chronic nephrotic syndromes and
kidney failure, are serious and extremely
complicated diseases. There are many potential
causes of kidney diseases, and therefore,
treatments vary depending on the exact etiology
and prognosis. If the conditions continue to
deteriorate, kidney dialysis, and eventually kidney
transplant may become necessary. Kidney
dialysis and transplant are generally considered
to be the last options, but they do prolong life and
offer additional hope.
Traditional Points
Ear Acupuncture
Traditional Points
To read articles by todays speaker, watch

online videos, or to see his/her complete
seminar/webinar schedule for this year, please
visit www.elotus.org
More information on the classic single herbs mentioned in

this seminar/webinar can be found in the
Chinese Medical Herbology and Pharmacology
More information on the classic formulas can be found in
the Chinese Herbal Formulas and Applications
Collection formulas can be found in the eLotus
Clinical Manual of Oriental Medicine
All the above texts are available through www.elotus.org

15
Herbs mentioned in this seminar/webinar, are

available through our sponsor Evergreen
Herbs & Medical Supplies. Please contact
them for a catalog and see how they can help
your practice.
This webinar is sponsored by:
Evergreen Herbs & Medical Supplies

Toll-free Tel: 866-473-3697
Website: www.evherbs.com
Email: sales@evherbs.com

16
Evergreen Herbs is not just an Herbal company, we are an

environmentally friendly, health conscious contributor to the healthcare community at large. Evergreen was founded by Dr. John Chen
and Tina Chen, siblings and coauthors of the Chinese Medical
Herbology and Pharmacology, and the Chinese Herbal Formulas
and Applications books.
Evergreen is a family business that is run by professionals like you
who care about Chinese medicine. And as a family business, we
have the well-being and satisfaction of our customers at the top
of our list. We care about the quality of our herbs, because we
care about our consumers, and have your best interest at heart.
Our goal is to support you in improving your clinical skills, and
enhancing the well-being of your patients.
To learn more about Evergreen Herbs and our products, please

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Intro to Herb-Drug Interactions for the

Collection Formulas, Part II

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Clinical Manual of Oriental Medicine, 2 edition

L.Ac., O.M.D., Pharm.D., Ph.D.

Pharm.D., Ph.D., O.M.D., L.Ac.

Lotus Institute Of Integrative Medicine

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Tel: (626) 780-7182 Fax: (626) 609-2929

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Wind, cold, heat, damp, etc.

ying (nutritive) level

Xue (blood) level

Pure red cell aplasia

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Any excess conditions characterized by

Zhi Zi (Fructus Gardeniae)

Bian Xu (Herba Polygoni

Long Dan (Radix et Rhizoma

[i] Hwang SM, Lee YJ, Yoon JJ, Lee SM,

Bai Hu Tang (White Tiger Decoction)

Long Dan Xie Gan Tang (Gentiana

Zhi Bai Di Huang Wan (Anemarrhena,

With bacterial infections, add Herbal ABX.

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Gardenia Complex and Herbal ABX are two

Gardenia Complex incorporates numerous antibiotic

Gardenia Complex is designed to purge heat in the

Therefore, although both formulas clear heat,

Given these two reasons, it is necessary to combine

[i] Zhong Yao Xue (Chinese Herbology), 1988; 140:144

Cautions & Contraindications

This formula is contraindicated in patients who have

K.B., a 62-year-old female, presented with

Systemic lupus erythematosus (SLE)

Lupus with inflammation in joints, tendons, and

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Bai Hua She She Cao (Herba Hedyotis)

Bai Hua She She Cao (Herba Hedyotis)

Jin Yin Hua (Flos Lonicerae Japonicae)

Bai Hua She She Cao (Herba Hedyotis)

Jin Yin Hua (Flos Lonicerae

[i] Zhong Yao Xue (Chinese Herbology), 1998; 204

[i] Xin Yi Xue (New Medicine), 1975; 6(3):155

Lian Qiao (Fructus Forsythiae)